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Pathophysiologie von Gallenblase und Gallenwegen

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Chirurgische Gastroenterologie
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Zusammenfassung

Während die Ausscheidung von toxischen Substanzen aus dem Blut in die Galle eine kontinuierliche Gallesekretion durch die Leber erfordert, ist für die Fettresorption im Darm die intermittierende, auf die Nahrungsaufnahme abgestimmte Abgabe von Galle ins Duodenum zweckmäßiger. Die Gallenblase hat die Aufgabe, die von der Leber sezernierte Galle zu speichern, zu konzentrieren und zum geeigneten Zeitpunkt nach den Mahlzeiten ins Duodenum abzugeben. Erstaunlicherweise führt die chirurgische Entfernung der Gallenblase jedoch kaum zu einer Beeinträchtigung der Fettresorption. Wenn auch Beobachtungen über Patienten vorliegen, bei denen nach der Cholecystektomie fettreiche Mahlzeiten zu Steatorrhoe führten [11], so konnten KRONDYL et al. [30] keine Abnahme der duodenalen Gallensäurenkonzentration oder Zunahme der fäcalen Fettausscheidung bei cholecystektomierten Personen nachweisen.

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Paumgartner, G. (1981). Pathophysiologie von Gallenblase und Gallenwegen. In: Allgöwer, M., Harder, F., Hollender, L.F., Peiper, HJ., Siewert, J.R. (eds) Chirurgische Gastroenterologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00618-4_94

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  • DOI: https://doi.org/10.1007/978-3-662-00618-4_94

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