Advertisement

Rhesusinkompatibilität und nicht immunologischer Hydrops fetalis

  • Manfred Hansmann
  • Bernhard-Joachim Hackelöer
  • Alfons Staudach
Chapter
  • 16 Downloads

Zusammenfassung

Die Rh-Inkompatibilität als geburtshilfliches Problem kann als gutes Beispiel dafür gelten, wie durch interdisziplinäre Zusammenarbeit von Spezialisten — in diesem Fall von Geburtshelfern, Pädiatern und Serologen — ein komplettes Krankheitsgeschehen aufgeklärt und (mit der notwendigen Einschränkung) auch beherrscht werden kann. Innerhalb von 30 Jahren wurde die Pathogenese erkannt, es gelang, ausreichend sichere diagnostische Methoden zu entwickeln und wirksame therapeutische Maßnahmen zu finden.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Asensio SH, Figueroa-Longo JG, Pelegrina IA (1966) Intrauterine exchange transfusion. Am J Obstet Gynecol 95:1128Google Scholar
  2. Berkowitz RL, Hobbins JC (1981) Intrauterine transfusion utilizing ultrasound. Obstet Gynecol 57: 33PubMedGoogle Scholar
  3. Bierme SJ, Blanc M, Abbal M, Fournie A (1979) Oral Rh-treatment for severely immunised mothers. Lancet I: 604CrossRefGoogle Scholar
  4. Bowman JM (1975) Rh erythroblastosis 1975. Semin Hematol 12:189PubMedGoogle Scholar
  5. Bowman JM (1978) The management of Rh-isoimmunization. Obstet Gynecol 52:1PubMedGoogle Scholar
  6. Bowman JM (1984) Rhesus haemolytic disease. In: Wald N (ed) Antenatal and neonatal screening. Oxford University Press, Oxford New York Tokyo, p 314Google Scholar
  7. Bowman JM, Manning FA (1983) Intrauterine fetal transfusions: Winnipeg 1982. Obstet Gynecol 61:203PubMedGoogle Scholar
  8. Charles AG, Blumenthal LS (1982) Promethazine hydrochloride therapy in severely Rh-sensitesed pregnancies Obstet Gynecol 60: 627Google Scholar
  9. Clewell WH, Dunne MG, Johnson ML, Bowes WA (1981) Fetal transfusion with real time ultrasound guidance. Obstet Gynecol 57: 516PubMedGoogle Scholar
  10. Cooperberg PL, Carpenter CW (1977) Ultrasound as an aid in intrauterine transfusion. Am J Obstet Gynecol 128: 239PubMedGoogle Scholar
  11. De Vore GR, Donnerstein RL, Kleinman CS, Platt LD, Hobbins JC (1982) Fetal echocardiography. II. The diagnosis and significance of a pericardial effusion in the fetus using real-time-directed M-mode ultrasound. Am J Obstet Gynecol 144: 693Google Scholar
  12. Dewhurst CJ, Beazly JM, Campbell S (1972) Assessment of fetal maturity and dysmaturity. Am J Obstet Gynecol 113: 141PubMedGoogle Scholar
  13. Finn R, Clarke CA, Donohoe WTA, Connel RB, Sheppard PM, Lehane D, Kulke W (1961) Experimental studies on the prevention of Rh hemolytic disease. Br Med J 1:1486PubMedCrossRefGoogle Scholar
  14. Freda VJ, Adamsons K (1964) Exchange transfusion in utero. Am J Obstet Gynecol 89: 817PubMedGoogle Scholar
  15. Freda VJ, Gorman JG, Pollack W (1964) Successful prevention of experimental Rh sensitization in man with an anti-Rh gamma 2 — globulin antibody preparation: A preliminary report. Transfusion 4: 26PubMedCrossRefGoogle Scholar
  16. Frigoletto FD, Umansky I, Birnholz J, Acker D, Easterday CL, Harris GBC, Griscom NT (1981) Intrauterinefetal transfusion in 365 fetuses during fifteen years. Am J Obstet Gynecol 139: 781PubMedGoogle Scholar
  17. Hamilton EG (1977) Intrauterine transfusion. Safeguard or penil? Obstet Gynecol 50: 255PubMedGoogle Scholar
  18. Hansmann M, Lang N (1972) Intrauterine Transfusion unter Ultraschallkontrolle. Klin Wochenschr 50:930PubMedCrossRefGoogle Scholar
  19. Hansmann M, Paulussen F, Weiß H, Niesen M, Lang N, Plotz E-J (1980) Intrauterine Transfusion unter Real-Time-Ultraschall-Kontrolle. In: Hinselmann M, Anliker M, Meudt R (Hrsg) Ultraschalldiagnostik in der Medizin, Thieme, Stuttgart New York, S 159Google Scholar
  20. Hardyment AF, Salvador HS, Towell ME, Carpenter CW, Jan FE, Tingle AJ (1979) Follow-up of intrauterine transfused surviving children. Am J Obstet Gyne-col 133: 235Google Scholar
  21. Harman CR, Manning FA, Bowman JM, Lange IR (1983) Severe Rh disease — Poor outcome is not inevitable. Am J Obstet Gynecol 145:823PubMedGoogle Scholar
  22. Hauth JC, Brekken AL, Pollack W (1981) Plasmapheresis as am adjunct to management of Rh isoimmunization. Obstet Gynecol 57:132PubMedGoogle Scholar
  23. Hobbins JC, Davis ED, Webster J (1976) A new technique utilizing ultrasound to aid in intrauterine transfusion. J Clin Ultrasound 4:135PubMedCrossRefGoogle Scholar
  24. Holzgreve W, Hansmann M (1984) Erfahrungen mit der „Free hand needle“ — Technik bei 3 21 5 Amniozentesen im II. Trimenon zur pränatalen Diagnostik. Gynäkologe 17: 77PubMedGoogle Scholar
  25. Knobbe T, Meier P, Wenar C, Cordero L (1979) Psychological development of children who received intrauterine transfusion. Am J Obstet Gynecol 133: 877PubMedGoogle Scholar
  26. Kopecky P (1971) Zur Diagnostik und Therapie der Rhesus-Inkompatibilität und Untersuchungen zum fe-talen Bilirubin-Metabolismus. Habilitationsschrift, RWTH AachenGoogle Scholar
  27. Kowalewski S, Kochs G, Kartheiser C, Hansmann M (1981) Untersuchungen zur Spätprognose von Kin-dern mit M. haemolyticus neonatorum (Rh) nach intratuterinen Transfusionen. 77. Tagung der Dtsch Ges Kinderheilk, Düsseldorf, 20.–23.09.1981Google Scholar
  28. Kwi NK, High NK (1974) A simple technique of intrauterine transfusion of fetus in University Hospital. Kuala Lumpur. Med J Malaysia 28: 287PubMedGoogle Scholar
  29. Landsteiner K, Wiener AS (1940) An agglutinable factor in human blood recognized by immune sera for rhesus blood. Proc Soc Exp Biol Med 43: 223Google Scholar
  30. Larkin RM, Knochel JQ, Lee TG (1982) Intrauterine transfusions: New techniques and results. Clin Obstet Gvnecol 25: 303CrossRefGoogle Scholar
  31. Levine P, Stetson R (1939) An unusual cease of intragroup agglutination. JAMA 113:126CrossRefGoogle Scholar
  32. Levine P, Katzin EM, Burnham L (1941) Isoimmunization in pregnancy: its possible bearing on the etiology of erythroblastosis fetalis. JAMA 116:825CrossRefGoogle Scholar
  33. Liley AW (1961) Liquor amnii analysis in the management of pregnancy complicated by rhesus sensitization. Am J Obstet Gynecol 82:1359PubMedGoogle Scholar
  34. Mast H (1969) Morbus haemolyticus neonatorum. Z Geburtshilfe 170 (Beilageheft)Google Scholar
  35. Parkman R, Mosier D, Umansky I, Cochran W, Carpenter CB, Rosen FS (1974) Graft-versus-host disease after intrauterine and exchange transfusions for hemolytic disease of the newborn. N Engl J Med 290:359PubMedCrossRefGoogle Scholar
  36. Peddle LJ, Campbell EM (1968) Radiation to the fetusg in intratuterine transfusion. Am J Obstet Gynecol 100:366PubMedGoogle Scholar
  37. Preisler O, Schneider J (1964) Versuche der Sensibilisierung Rh-negativen Frauen durch antikörperhaltige Seren zu verhindern. Geburtshilfe Frauenheilkd 24:124PubMedGoogle Scholar
  38. Queenan JT, Wyatt RH (1965) Intrauterine transfusion of fetus for severe erythroblastosis fetalis. Am J Obstet Gynecol 92: 375PubMedGoogle Scholar
  39. Queenan JT, Anderson GG, Mead PB (1966) Intrauterine transfusion by the multiple needle technique. JAMA 196: 664PubMedCrossRefGoogle Scholar
  40. Rodeck CH, Nicolaides KH (1984) Anwendung der Fetoskopie bei fetaler Therapie. Gynäkologe 17: 52PubMedGoogle Scholar
  41. Rodeck CH, Holman CA, Karnicki J, Kemp JR, Whitmore DN, Austin MA (1981) Direct intravascular fetal blood transfusion by fetoscopy in severe rhesus isoimmunisation. Lancet I: 625CrossRefGoogle Scholar
  42. Schneider J, Maas DHA (1978) Rhesuserythroblastose. Klin Frauenheilkd III:164/1 (Ergänzung 1978)Google Scholar
  43. Seelen J, Kessel, Hiam V, Eskes T, Leusden H V, Been K, Evers J, Gent D V, Peeters L, Velden W, Zonderland FCD (1966) A new method of exchange transfusion in utero. Am J Obstet Gynecol 95:872PubMedGoogle Scholar
  44. White CA, Goplerud CP, Kisker CT, Stehbens JA, Kitchell M, Taylor JC (1978) Intrauterine fetal transfusion, 1965–1976, with an assessment of the surviving children. Am J Obstet Gynecol 130: 933PubMedGoogle Scholar
  45. Whitfield CR, Thompson W, Armstrong M, Reid McC (1972) Intrauterine fetal transfusion for severe rhesus haemolytic disease. Br J Obstet Gynaecol 79: 931CrossRefGoogle Scholar
  46. Andersen HM, Drew JH, Beischer NA, Hutchison AA, Fortune DW (1983) Non-immune hydrops fetalis: Changing contribution to perinatal mortality. Br J Obstet Gynaecol 90: 636PubMedCrossRefGoogle Scholar
  47. Chervenak FA, Isaacson G, Blakemore KJ, Breg WR, Hobbins JC, Berkowitz RL, Tortora M, Mayden K, Mahoney MJ (1983) Fetal cystic hygroma. Cause and natural history. N Engl J Med 309: 822PubMedCrossRefGoogle Scholar
  48. Clausen U, Hansmann M (1984) Die „Pipettenmethode“ zur schnellen Karyotypisierung bei sonographischen Verdachtskriterien für eine Chromosomenanomalie. Gynäkologe 17: 33Google Scholar
  49. Daffos F, Capella-Pavlovsky M, Forestier F (1983) Fetal blood sampling via the umbilical cord using a needle guided by ultrasound: Report of 66 cases. Prenat Diagn 3:271PubMedCrossRefGoogle Scholar
  50. Davis CL (1982) Diagnosis and management of nonimmune hydrops fetalis. J Reprod Med 27: 594PubMedGoogle Scholar
  51. DeVore GR, Donnerstein RL, Kleinmann CS, Platt LD, Hobbins JC (1982) Fetal echocardiography. II. The diagnosis and significance of a pericardial effusion in the fetus using real-time-directed M-mode ultrasound. Am J Obstet Gynecol 144: 693PubMedGoogle Scholar
  52. DeVore GR, Siassi B, Platt LD (1983) Fetal echocar-diography. III. The diagnosis of cardiac arrhythmias using real-time-directed M-mode ultrasound. Am J Obstet Gynecol 146: 792PubMedGoogle Scholar
  53. Etches PC, Lemons JA (1979) Nonimmune hydrops fetalis: Report of 22 cases including three siblings. Pediatrics 64: 326PubMedGoogle Scholar
  54. Fleischer AC, Killam AP, Boehm FH, Hutchison AA, Jones TB, Shaff MI, Barrett JM, Lindsey AM, James AE (1981) Hydrops fetalis: Sonographic evaluation and clinical implications. Radiology 141:163PubMedGoogle Scholar
  55. Golbus MS (1984) The status of fetoscopy and fetal tissue sampling. Prenat Diann 4: 79CrossRefGoogle Scholar
  56. Hansmann M (1981) Nachweis und Ausschluß fetaler Entwicklungsstörungen mittels Ultraschallscreening und gezielter Untersuchung — ein Mehrstufenkonzept. Ultraschall 2: 206CrossRefGoogle Scholar
  57. Hansmann M, Gembruch U (1984) Symptome und Behandlung möglicher fetaler Herzkrankheiten. 93. Tagung der Nordwestdeutschen Gesellschaft für Gynäkologie und Geburtshilfe. Alete Wissenschaftlicher Dienst, München, S. 56Google Scholar
  58. Hansmann M, Redel DA (1982) Prenatal symptoms and clinical management of heart disease. In: 1er symposium international d’echocardiologie foetale, Strasbourg 1982, p 137Google Scholar
  59. Hansmann M, Redel DA, Födisch HJ (1982) Premature obstruction of the foramen ovale detected, treated and reconfirmed by help of ultrasound. In: Burruto F, Hansmann M, Wladimiroff JW (eds) Fetal ultrason-ography: The secret prenatal life. Wiley, Chichester New York 151Google Scholar
  60. Hutchison AA, Drew JH, Yu VYH, Williams ML, Fortune DW, Beischer NA (1982) Nonimmunologic hydrops fetalis: a review of 61 cases. Obstet Gynecol 59: 347PubMedGoogle Scholar
  61. Kleinman CS, Donnerstein RL, DeVore GR, Jaffe CC, Lynch DC, Berkowitz RL, Talner NS, Hobbins JC (1982) Fetal echocardiography for evaluation of in utero congestive heart failure. N Engl J Med 306: 568PubMedCrossRefGoogle Scholar
  62. Kleinman CS, Donnerstein RL, Jaffe CC, DeVore GR, Weinstein EM, Lynch DC, Talner NS, Berkowitz RL, Hobbins JC (1983) Fetal echocardiography. A tool for evaluation of in utero cardiac arrhythmias and monitoring of in utero therapy: Analysis of 71 patients. Am J Cardiol 51:237PubMedCrossRefGoogle Scholar
  63. Macafee CAJ, Fortune DW, Beischer NA (1970) Nonimmunological hydrops fetalis. Br J Obstet Gynaecol 77: 226CrossRefGoogle Scholar
  64. Machin GA (1981) Differential diagnosis of hydrops fetalis. Am J Med Genet 9: 341PubMedCrossRefGoogle Scholar
  65. Maidman JE, Yeager C, Anderson V, Makabali G O, Grady P, Arce J, Tishler DM (1980) Prenatal diag29 nosis and management of nonimmunologic hydrops fetalis. Obstet Gynecol 56: 571PubMedGoogle Scholar
  66. Perlin BM, Pomerance JJ, Schifrin BS (1981) Nonimmunologic hydrops fetalis. Obstet Gynecol 57: 584PubMedGoogle Scholar
  67. Potter EL (1983) Universal edema of the fetus unassociated with erythroblastosis. Am J Obstet Gynecol 46 130Google Scholar
  68. Redel DA, Hansmann M (1981) Fetal obstruction of the foramen ovale detected by two-dimensional doppler echocardiography. In: Rijsterborgh H (ed) Echocardiology. Nijhoff, The Hague Boston London, p 425CrossRefGoogle Scholar
  69. Redel DA, Hansmann M (1982) Prenatal diagnosis and treatment of heart disease. In: 1er symposium international d’echocardiologie foetale, Strasbourg 1982, p 137Google Scholar
  70. Redel DA, Hansmann M (1984) Fetale Echokardiographie — ihre Anwendung in Diagnostik und Therapie. Gynäkologe 17: 41PubMedGoogle Scholar
  71. Rodeck CH, Nicolaides KH (1984) Die Anwendung der Fetoskopie bei fetaler Therapie. Gynäkologe 17: 52PubMedGoogle Scholar
  72. Rudolph A (1974) Congenital diseases of the heart. Year Book Medical Publishers, ChicagoGoogle Scholar
  73. Schwartz SM, Viseskul C, Laxova R, McPherson EW, Gilbert EF (1981) Idiopathic hydrops fetalis. Report of 4 patients including 2 affected sibs. Am J Med Genet 8: 59PubMedCrossRefGoogle Scholar
  74. Senft HH, Födisch HJ, Hansmann M (1982) Hydrops fetalis. Fragen der prä- und postnatalen Diagnostik sowie der Pathogenese. Verh Dtsch Ges Pathol 66:164PubMedGoogle Scholar
  75. Staab D, Schlemminger R, Emons D, Hansmann M, Kowalewski S (1984) Darmperforation als Ursache des fetalen Aszites. INA Bd 47. Kowalewski S (Hrsg) Pädiatrische Intensivmedizin VI. Thieme, Stuttgart New York, S. 86Google Scholar
  76. Turski DM, Shahadi N, Viseskul C, Gilbert E (1978) Non-immunologic hydrops fetalis. Am J Obstet Gynecol 131: 586PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Manfred Hansmann
    • 1
  • Bernhard-Joachim Hackelöer
    • 2
  • Alfons Staudach
    • 3
  1. 1.Abteilung für Pränatale Diagnostik und TherapieUniversitäts-FrauenklinikBonn 1Deutschland
  2. 2.Medizinisches Zentrum für Frauenheilkunde und GeburtshilfePhilipps-UniversitätMarburgDeutschland
  3. 3.LandesfrauenklinikLandeskrankenhaus SalzburgSalzburgÖsterreich

Personalised recommendations