Advertisement

Malnutrition and Disorders of Intestinal Malabsorption

  • M. S. R. Hutt
  • H. Spencer
Part of the Spezielle pathologische Anatomie book series (SPEZIELLE, volume 8)

Abstract

The commonest form of malnutrition in the tropics is protein calorie malnutrition (P.C.M.) of childhood. The spectrum of clinical features associated with this type of malnutrition is characterised at one extreme by mar asmus which results from a gross deficiency of calories and, at the other extreme, by kwashiorkor which results from a primary deficiency of protein. Many variants are present within this spectrum depending on the ratio of deficiency of protein and calories and also on other factors such as the inorganic and vitamin content of the diet. In describing the aetiology of these conditions it will be necessary to refer to the more pure states, but it must be evident that in all cases the deficiencies involve to some extent both protein and calorie deficiency.

Keywords

Coeliac Disease Malabsorption Syndrome Childhood Malnutrition Tropical Sprue Intestinal Malabsorption 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

Childhood Malnutrition

  1. Adams, E. B., Scragg, J. N., Naidoo, B. T., Liljestrand, S. K., Cockram, V. I.: Observations on the aetiology and treatment of anaemia in kwashiorkor. Brit. med. J. 3, 451 (1967) .PubMedCrossRefGoogle Scholar
  2. Allen, D. M., Dean, R. F. A.: The anaemia of kwashiorkor in Uganda. Trans. roy. Soc. trop. Med. Hyg. 59, 326 (1965) .PubMedCrossRefGoogle Scholar
  3. Arroyave, G., Wilson, D.: Urinary excretion of creatinine of children under different nutritional conditions. Amer. J. clin. Nutr. 9, 170 (1961) .PubMedGoogle Scholar
  4. Cook, G. C., Lee, F. D.: The jejunum after kwashiorkor. Lancet 1966 II, 1263.CrossRefGoogle Scholar
  5. Edington, G. M., Gilles, H. M.: Pathology in the tropics. London: Edward Arnold 1969.Google Scholar
  6. Hutt, M. S. R.: Some aspects of liver disease in Ugandan Africans. Trans. roy. Soc. trop. Med. Hyg. 65, 273 (1971) .PubMedCrossRefGoogle Scholar
  7. Jelliffe, D. B.: The assessment of the nutritional status of the community (with special reference to field surveys in developing regions of the world) . Wld Hlth Org. Monogr. Ser. 53 (1966) .Google Scholar
  8. Jelliffe, E. F., Jelliffe, D. B.: The arm circumference as a public health index of proteincalorie malnutrition of early childhood. J. trop. Pediat. 15 (Monogr. No. 8), 179 (1969) .CrossRefGoogle Scholar
  9. Morley, D. C.: Severe measles in the tropics. Brit. med. J. I, 297 (1969) .CrossRefGoogle Scholar
  10. Mugerwa, T.: The lymphoreticular system in kwashiorkor. J. Path. 105, 105 (1971a).PubMedCrossRefGoogle Scholar
  11. Mugerwa, J.: M.D.Thesis, University of East Africa (1971b).Google Scholar
  12. Owor, R.: Pathological features of chronic pancreatic disease in Uganda. E. Afr. med. J. 47, 604 (1970).Google Scholar
  13. Stanfield, J. P., Hutt, M. S. R., Tunnicliffe, R.: Intestinal biopsy in kwashiorkor. Lancet 1965 II, 519.CrossRefGoogle Scholar
  14. Templeton, A. C.: Generalised herpes simplex in malnourished children. J. clin. Path. 23, 24 (1970) .PubMedCrossRefGoogle Scholar
  15. Trowell, H. C., Davies, J. N. P., Dean, R. F. A.: Kwashiorkor. London: Edward Arnold 1954.Google Scholar
  16. Vint, F. W.: Post-mortem findings in the natives of Kenya. E. Afr. med. J. 13, 332 (1937) .Google Scholar
  17. Watts, T.: Thymus weights in malnourished children. J. trop. Pediat. 15, 155 (1969) .PubMedCrossRefGoogle Scholar
  18. Whitehead, R. G.: Rapid determination of some plasma aminoacids in sub-clinical kwashiorkor. Lancet 1964 I, 250.CrossRefGoogle Scholar
  19. Whitehead, R. G.: Hydroxyproline creatinine ratio as an index of nutritional status and rate of growth. Lancet 1965 II, 567.CrossRefGoogle Scholar
  20. Whitehead, R. G.: Biochemical tests for assessing subclinical nutritional deficiency. Clin. Pediat. 6, 516 (1968) .CrossRefGoogle Scholar
  21. Wld Hlth Org. Expert Committee on Medical Assessment of nutritional status. Techn. Rep. Ser. 258 (1963) .Google Scholar

Nutritional Siderosis

  1. Banwell, J. G., Hutt, M. S. R., Leonard, P. J., Blackman, V., Connor, D. H., Marsden, P. D., Campbell, J.: Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa. Gut 8, 388 (1967) .PubMedCrossRefGoogle Scholar
  2. Bradlow, B. A., Dunn, J. A., Higginson, J.: The effect of cirrhosis on iron storage. Amer. J. Path. 39, 221 (1961) .PubMedGoogle Scholar
  3. Charlton, R. W., Bothwell, T. H.: Hemochromatosis: dietary and genetic aspects. Progr. Hemat. 5, 298 (1966) .Google Scholar
  4. Dodu, S. R. A.: Diabetes and haemosiderosis - haemochromatosis — in Ghana. Trans. roy. Soc. trop. Med. Hyg. 52, 425 (1958) .PubMedCrossRefGoogle Scholar
  5. Edington, G. M.: Nutritional siderosis in Ghana. Cent. Afr. J. Med. 5, 186 (1959) .PubMedGoogle Scholar
  6. Gillman, J., Gillman, T.: Perspectives in human malnutrition. New York: Grune and Stratton 1951.Google Scholar
  7. Gillman, T., Canham, P. A. S., Hathorn, M.: Experimental nutritional siderosis. Lancet 1958 II, 557.CrossRefGoogle Scholar
  8. Gillman, T., Hathorn, M., Canham, P. A. S.: Experimental dietary siderosis. Amer. J. Path 35, 349 (1959) .PubMedGoogle Scholar
  9. Haddock, D. R.: Bantu siderosis in Tanzania. E. Afr. med. J. 42, 67 (1965).Google Scholar
  10. Higginson, J., Gerritsen, T., Walker, A. R. P.: Siderosis in the Bantu of Southern Africa. Amer. J. Path. 29, 779 (1953) .PubMedGoogle Scholar
  11. Hutt, M. S. R.: Some aspects of liver disease in Ugandan Africans. Trans. roy. Soc. trop. Med. Hyg. 65, 273 (1971) .PubMedCrossRefGoogle Scholar
  12. Lowenthal, M. N., Hamilton, P. J. S., Hutt, M. S. R., Wilks, N. E.: Big. spleen disease in Zambia. Cent. Afr. J. Med. 12, 99 (1966) .Google Scholar
  13. Macdonald, R. A.: Primary hemochromatosis: inherited or acquired? Progr. Hemat. 5, 324 (1966) .Google Scholar
  14. Owor, R.: M.D. Thesis, University of East Africa 1971.Google Scholar
  15. Seftel, H. C., Isaacson, C., Bothwell, T. H.: The relationship between siderosis and diabetes in the Bantu. S. Afr. med. J. 25, 89 (1960) .Google Scholar
  16. Wainwright, J.: Siderosis in the African. S. Afr. J. Lab. clin. Med. 1, 1 (1957) .Google Scholar

Sprue

  1. Baker, S. T.: Tropical sprue. Brit. med. Bull. 28, 87 (1972) .PubMedGoogle Scholar
  2. Baker, S. J., Ignatius, M., Mathan, V. I., Vaish, S. K., Chako, C. C.: Intestinal biopsy in tropical sprue. In: Ciba Foundation Study Group, No. 14, p. 84. Boston: Little, Brown 1962.Google Scholar
  3. Gorbach, S. L., Mitra, R., Jacobs, B., Banwell, J. G., Chatterjee, B. D., Guha Mazumder, D. N.: Bacterial contamination of the upper small bowel in tropical sprue. Lancet I, 74 (1969) .CrossRefGoogle Scholar
  4. Gray, G. M., Walter, W. M., Jr., Colver, E. H.: Persistent deficiency of intestinal lactase in apparently cured tropical sprue. Gastroenterology 54, 552 (1968) .PubMedGoogle Scholar
  5. O’brien, W., England, M. W. J.: Military tropical sprue from South-East Asia. Brit. med. J. II, 1157 (1966) .CrossRefGoogle Scholar
  6. Sheehy, T. W., Anderson, P. R.: Disaccharidase activity in normal and diseased small bowel. Lancet II, 1 (1965) .CrossRefGoogle Scholar
  7. Swanson, V. L., Thomassen, R. W.: Pathology of the jejunal mucosa in tropical sprue. Amer. J. Path. 46, 511 (1965) .PubMedGoogle Scholar
  8. Wheby, M. S., Swanson, V. L., Bayless, T. M.: Comparison of ileal and jejunal biopsies in tropical sprue. Amer. J. clin. Nutr. 24, 117 (1971) .PubMedGoogle Scholar

Chronic Pancreatic Disease

  1. Banwell, J. G., Hutt, M. S. R., Leonard, P., Blackman, V., Connor, D. W., Marsden, P., Campbell, J.: Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa. Gut. 8, 388 (1967) .PubMedCrossRefGoogle Scholar
  2. Bourgoignie, J., Sonet, J., Dechef, G.: Etude clinique du diabete sucre du Bantou de la region de Leopoldville. Ann. Soc. belge Med. Trop. 42, 261 (1962) .PubMedGoogle Scholar
  3. Geevarghese, P. J., Pitchumoni, E. S.: Pancreatic diabetes in Kerala, India. Proceedings of the World Congress on Diabetes in the Tropics. Bombay, India. Edited by J. C. Patel and N. G. Talwalker, p. 223 (1966) .Google Scholar
  4. Kajubi, S. K., Shaper, A. G., Owor, R.: Chronic Pancreatic Disease. Medicine in a Tropical Environment. Eds. Shaper, A. G., Kibukamusoke, J. W., Hutt, M. S. R. Brit. med. Ass., London 1972.Google Scholar
  5. Kinnear, T. W. G.: The pattern of diabetes mellitus in a Nigerian teaching hospital. East African Medical Journal. 40, 288 (1963f) .PubMedGoogle Scholar
  6. Owor, R.: Pathological features of chronic pancreatic disease in Uganda. East African Medical Journal 47, 604 (1970) .PubMedGoogle Scholar
  7. Owor, R.: Chronic Pancreatic Disease: A common cause of obstructive jaundice. East African Medical Journal 49, 614 (1972).PubMedGoogle Scholar
  8. Parson, W., Macdonald, F., Shaper, A. G.: African diabetics necropsied at Mulago Hospital, Kampala. 1957–1966. East African Medical Journal 45, 89 (1968).PubMedGoogle Scholar
  9. Shaper, A. G.: Observations on the incidence and nature of chronic pancreatic disease in African diabetics in Uganda. Proceedings of the 4th Congress International Diabetes Federation, Geneva. 1, 119 (1961) .Google Scholar
  10. Zuidema, P. J.: Cirrhosis and disseminated calcification of the pancreas in patients with malnutrition. Trop. geog. Med. 11, 70 (1959) .Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1973

Authors and Affiliations

  • M. S. R. Hutt
  • H. Spencer

There are no affiliations available

Personalised recommendations