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Skin Diseases Due to Physical and Chemical Causes

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Dermatology

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Abstract

The skin responds to acute and chronic mechanical damage in different ways. In acute mechanical skin irritation, such as from friction, there is cleavage between the dermis and epidermis and blisters form. In the thick skin of palms and soles, the cleavage may be in the epidermis from shear stress. Chronic or intermittent irritations of lower intensity induce epidermopoiesis with acanthosis and hyperkeratosis, and thereby epidermal thickening. Also, the melanocyte system can be stimulated to melanopoiesis by mechanical skin irritation. When the skin reacts excessively to mechanical injury, congenital disorders such as hereditary epidermolysis or cutis hyperelastica (Ehlers-Danlos syndrome) must be considered.

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Authors and Affiliations

  1. Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Frauenlobstrasse 9-11, 8000, München 2, Federal Republic of Germany

    Professor Dr. med., Dr. med. h.c. mult. Otto Braun-Falco

  2. Hautklinik der Heinrich-Heine-Universität, Moorenstrasse 5, 4000, Düsseldorf, Federal Republic of Germany

    Professor Dr. med. Gerd Plewig

  3. Klinik für Dermatologie und Venerologie, Medizinischen Universität zu Lübeck, Ratzeburger Allee 160, 2400, Lübeck 1, Federal Republic of Germany

    Professor Dr. med. Helmut H. Wolff

  4. Dermatology — Dermatopathology, Mayo Clinic, Mayo Medical School, 200 First Street SW, 55905, Rochester, MN, USA

    Professor Richard K. Winkelmann MD

Authors
  1. Professor Dr. med., Dr. med. h.c. mult. Otto Braun-Falco
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  2. Professor Dr. med. Gerd Plewig
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  3. Professor Dr. med. Helmut H. Wolff
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  4. Professor Richard K. Winkelmann MD
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© 1991 Springer-Verlag Berlin Heidelberg

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Braun-Falco, O., Plewig, G., Wolff, H.H., Winkelmann, R.K. (1991). Skin Diseases Due to Physical and Chemical Causes. In: Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00181-3_13

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  • DOI: https://doi.org/10.1007/978-3-662-00181-3_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-00183-7

  • Online ISBN: 978-3-662-00181-3

  • eBook Packages: Springer Book Archive

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