Some Variations in Childhood Cancers Throughout the World

  • J. N. P. Davies
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 13)


Despite the high proportion which children form of the total population of tropical and sub-tropical countries paediatrics was till recent years a very neglected field and when in 1958 BRAS [1] surveyed what was known of childhood neoplasia in such countries it was the most dark and dismal part of this neglected field. Very little information was available; this was not surprising because even in medically advanced countries the subject had attracted little attention till, with the decline in other lethal diseases in childhood, it became a major cause of death. In many countries there has been little decline in the other fatal diseases of childhood. If children with cancer were brought to medical attention they often came late, no effective treatment was available and usually the only purpose of a biopsy was to exclude some more readily treatable condition. If the situation has changed somewhat since 1958 it is because there has been a heightened interest in the geography and epidemiology of cancer [2, 3] and its influencing factors and because it has become evident that, as with adults so with children, there are striking variations in the site and type frequencies of cancer from country to country that almost certainly reflect the effect of environmental influences. Particularly in Africa [4, 5, 6, 7] have cancer surveys been set up in a concerted effort to obtain cancer incidence rates in selected areas and though chiefly concerned with adult cancers these have provided much information about cancer in childhood there and elsewhere [8]. At the same time much interest has been aroused by the curious features of solid lymphomatous tumours in children in Africa [9, 10]. Particular attention will therefore be devoted in this chapter to African experiences.


Malignant Lymphoma Childhood Cancer Childhood Leukemia African Child Granulosa Cell Tumour 
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  • J. N. P. Davies

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