Paper 9: microRNA in non-melanoma skin cancer

  • Michael Sand
Chapter

Abstract

MicroRNAs (miRNAs) are 17- to 23-nucleotide (nt), short, non-coding RNA molecules that are capable of regulating gene expression at a posttranscriptional level. Encoded within both exons and introns, they play a pivotal role in a variety of physiologic cellular functions and diseases, including cancer. Approximately 30%–60% of all human genes are affected by miRNA regulation, and our understanding of their role as both tumor suppressors and oncogenes in a variety of different cancers is gradually evolving. In this mini-review, we summarize the current knowledge on the role of miRNAs in non-melanoma skin cancer (NMSC). All the differentially expressed miRNAs in NMSC have been compiled in table 12-1.

Keywords

Estrogen Adenocarcinoma Oncol Nucleoside Diphosphate 

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Copyright information

© Springer Fachmedien Wiesbaden 2016

Authors and Affiliations

  • Michael Sand
    • 1
  1. 1.BochumGermany

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