Abstract
MicroRNAs (miRNAs) are 17- to 23-nucleotide (nt), short, non-coding RNA molecules that are capable of regulating gene expression at a posttranscriptional level. Encoded within both exons and introns, they play a pivotal role in a variety of physiologic cellular functions and diseases, including cancer. Approximately 30%–60% of all human genes are affected by miRNA regulation, and our understanding of their role as both tumor suppressors and oncogenes in a variety of different cancers is gradually evolving. In this mini-review, we summarize the current knowledge on the role of miRNAs in non-melanoma skin cancer (NMSC). All the differentially expressed miRNAs in NMSC have been compiled in table 12-1.
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© 2016 Springer Fachmedien Wiesbaden
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Sand, M. (2016). Paper 9: microRNA in non-melanoma skin cancer. In: MicroRNAs in malignant tumors of the skin. Springer, Wiesbaden. https://doi.org/10.1007/978-3-658-12794-7_13
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DOI: https://doi.org/10.1007/978-3-658-12794-7_13
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Publisher Name: Springer, Wiesbaden
Print ISBN: 978-3-658-12793-0
Online ISBN: 978-3-658-12794-7
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