Studies on the Immunosuppressive Activity of L-Asparaginase

  • R. Maral
  • J. C. Guyonnet
  • L. Julou
  • Y. de Ratuld
  • G. H. Werner
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 33)

Abstract

The immunological study of L-asparaginase is of interest for two main reasons: first, this enzyme is immunogenic; this effect may explain the appearance of resistance in mice bearing a leukemia which is sensitive to the drug (Waravdekar and Goldin, 1969) (personal unpublished findings); secondly, L-asparaginase shows immunosuppressive activities in a number of tests.

Keywords

Arthritis Agar Leukemia Dium Asparagine 

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Copyright information

© Springer-Verlag Berlin • Heidelberg 1970

Authors and Affiliations

  • R. Maral
    • 1
  • J. C. Guyonnet
    • 1
  • L. Julou
    • 1
  • Y. de Ratuld
    • 1
  • G. H. Werner
    • 1
  1. 1.Research LaboratoriesSociété des Usines ChimiquesFrance

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