Interrelation of the Nervous and Endocrine Factors in Regulation of Melanocytes

  • A. A. Voitkevich


In recent years, interest in the neurohumoral control of the hypophyseal pars intermedia has greatly increased. It has been provoked by signs of differentiation of intermedin participation in metabolic processes and in animal pigment reactions. Reaction of the pigment cell is, as a rule, a final phase in a number of metabolic processes which have a hormonal conditionality. Many authors consider the neurohormonal control of both pigment production and skin colour to be a result of common genesis of the melanoblasts and nervous cells. Occurrence of MSH in the hypothalamic corticotrophin-releasing factor and intimate chemical interference of MSH and ACTH show that the hormonal principles of the pars intermedia take part in numerous adaptation reactions which are realized by the hypothalamus-hypophysis-adrenal cortex system.


Pituitary Gland Hypertonic Saline Pigment Cell Median Eminence Skin Hyperpigmentation 
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© Springer-Verlag Berlin · Heidelberg 1966

Authors and Affiliations

  • A. A. Voitkevich
    • 1
  1. 1.Laboratory of Neuroendocrinology, Institute of Medical RadiologyAcademy of Medical SciencesObninskUSSR

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