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Ontogenetic Effects

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Cholinesterases and Anticholinesterase Agents

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 15))

Abstract

Cholinesterases (ChE’s), enzymes intimately concerned with synaptic transmission as well as with motor activity (“overt behavior”), teleologically should appear in phylogenesis and in ontogenesis at the first occurrence of transmission and of behavioral events. Pertinent results were described and discussed in Chapter 5; while they bear out the general importance of ChE’s and particularly of acetylcholinesterase (AChE) for rapidly occurring functions, their coupling with specific phylo- or ontogenetic steps could not be successfully pinpointed in many cases; moreover, it was found expedient to suggest that these enzymes may also play a part in processes other than transmission.

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Authors
  1. Alexander G. Karczmar
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Editors and Affiliations

  1. Department of Pharmacology, Schools of Medicine, University of Pennsylvania, Philadelphia 4, Pa., USA

    George B. Koelle Ph.D., M.D. (Professor and Chairman) (Professor and Chairman)

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© 1963 Springer-Verlag Berlin Heidelberg

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Karczmar, A.G. (1963). Ontogenetic Effects. In: Koelle, G.B. (eds) Cholinesterases and Anticholinesterase Agents. Handbook of Experimental Pharmacology, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-99875-1_17

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  • DOI: https://doi.org/10.1007/978-3-642-99875-1_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-99877-5

  • Online ISBN: 978-3-642-99875-1

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