Hyalin is a poorly understood and even poorly defined word. It means “glassy or translucent substance” and has been applied to proteins that are amorphous and stain in such a fashion but lack other distinguishing characteristics. Hyaline is the corresponding adjective. In the skin, a hodgepodge of different materials have been identified. Some authors include amyloid and gouty tophi under hyalins; others specifically exclude these substances. The overproduction of carbohydrate-rich glycoproteins is the usual explanation for their genesis. Several exceedingly rare disorders are traditionally considered “hyalinoses”.
KeywordsHuman Skin Fibroblast Proteus Syndrome Autosomal Recessive Pattern Gouty Tophus Hyaline Material
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- Gruber F, Manestar D, Stasic A et al. (1996) Treatment of lipoid proteinosis with etretinate (letter). Acta Derm Venereol (Stockh) 76: 154–155Google Scholar
- Hofer PA, Larsson PA, Ek B et al. (1974) A clinical and histo-pathological study of twenty-seven cases of Urbach-Wiethe disease. Dermatologic, gastroenterologic, neuro-physiologie, ophthalmologie, and Roentgen-diagnostic aspects, as well as the results of some clinicochemical and histochemical examinations. Acta Pathol Microbiol Scand [A] Suppl 245: 1–87Google Scholar
- Murray J (1873) On three peculiar cases of molluscum fibro-sum in children. Med Chir Trans 38: 235–253Google Scholar
- Wiethe C (1924) Kongenitale, diffuse Hyalinablagerungen in den oberen Luftwegen, familiär auftretend. Z Hals Nasen Ohrenheilkd 10: 359–362Google Scholar