Skip to main content
Book cover

Dermatology pp 697–708Cite as

Pustular Diseases

  • Chapter

Abstract

One unusual feature of the skin is its tendency to form sterile pustules. Nondermatologists have often been taught to equate pus with infection and find the nonchalance of dermatologists’ approach to pus puzzling. While many bacterial, viral, and fungal infections in the skin are indeed pustular, there are also many patients who present with sterile pustules. The prototypical pustular disease is psoriasis. Presumably, a number of noninfectious triggers can also produce the appropriate cytokines for eliciting a pustular response in the skin. In this chapter, we will discuss the idiopathic pustular diseases, dividing them as shown in Table 16.1 into acral and generalized conditions while also distinguishing between the childhood and adult forms.

Table 16.1 Idiopathic pustular diseases

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Bibliography

Infantile Acropustulosis

  • Dromy R, Raz A, Metzker A (1991) Infantile acropustulosis. Pediatr Dermatol 8: 284–287

    Article  PubMed  CAS  Google Scholar 

  • Kahn G, Rywlin AM (1979) Acropustulosis of infancy. Arch Dermatol 115: 831–833

    Article  PubMed  CAS  Google Scholar 

  • Mancini AJ, Frieden IJ, Palier AS (1998) Infantile acropustulosis revisited: history of scabies and response to topical corticosteroids. Pediatr Dermatol 15: 337–341

    Article  PubMed  CAS  Google Scholar 

  • Newton JA, Salisbury J, Mardsen A et al. (1986) Acropustulosis of infancy. Br J Dermatol 115: 735–739

    Article  PubMed  CAS  Google Scholar 

  • Van Praag MC, Van Rooij RW, Folkers E et al. (1997) Diagnosis and treatment of pustular disorders in the neonate. Pediatr Dermatol 14: 131–143

    Article  PubMed  Google Scholar 

  • Vignon-Pennamen MD, Wallach D (1986) Infantile acropustulosis. A clinicopathologic study of six cases. Arch Dermatol 122: 1155–1160

    Article  PubMed  CAS  Google Scholar 

Parakeratosis Pustulosa

  • Hjorth N, Thomsen K (1967) Parakeratosis pustulosa. Br J Dermatol 79: 527–532

    Article  PubMed  CAS  Google Scholar 

  • Sabouraud R (1931) Les parakératoses microbiènnes du bouts des doigts. Ann Dermatol Syphil 11: 206

    Google Scholar 

  • Tosti A, Peluso AM, Zucchelli V et al. (1998) Clinical findings and long-term follow-up of 20 cases of parakeratosis pustulosa. Pediatr Dermatol 15: 259–263

    Article  PubMed  CAS  Google Scholar 

Acrodermatitis Continua Suppurativa

  • Behrens S, von Kobyletzki G, Hoffmann K et al. (1997) PUVA-Bad-Photochemotherapie bei Acrodermatitis continua suppurativa Hallopeau. Hautarzt 48: 824–827

    Article  PubMed  CAS  Google Scholar 

  • Hallopeau M (1890) Sur une asphyxie locale des extremities avec polydactylite suppurative chronique et pouseés epheméres dermatitae pustuleuse disséminée et symetrique. Bull Soc Fr Dermatol Syph 1: 39–45

    Google Scholar 

  • Kuijpers AL, van Dooren-Grebe RJ, van de Kerkhof PC (1996) Acrodermatitis continua of Hallopeau: response to combined treatment with acitretin and calcipotriol ointment. Dermatology 192: 357–359

    Article  PubMed  CAS  Google Scholar 

  • Pearson LH, Allen BS, Smith JG Jr (1984) Acrodermatitis continua of Hallopeau: treatment with etretinate and review of relapsing pustular eruptions of the hands and feet. J Am Acad Dermatol 11: 755–762

    Article  PubMed  CAS  Google Scholar 

  • Piraccini BM, Fanti PA, Morelli R et al. (1994) Hallopeau’s acrodermatitis continua of the nail apparatus: a clinical and pathological study of 20 patients. Acta Derm Venereol (Stockh) 74: 65–67

    CAS  Google Scholar 

Palmoplantar Pustulosis

  • Andrews GC, Birkman FW, Kelly RJ (1934) Recalcitrant pustular eruptions of the palms and soles. Arch Dermatol Syphil 29: 548–563

    Article  Google Scholar 

  • Burge SM, Ryan TJ (1985) Acute palmoplantar pustulosis. Br J Dermatol 113: 77–83

    Article  PubMed  CAS  Google Scholar 

  • Eriksson MO, Hagforsen E, Lundin IP et al. (1998) Palmoplantar pustulosis: a clinical and immunohistological study. Br J Dermatol 138: 390–398

    Article  PubMed  CAS  Google Scholar 

  • Lindelöf B, Beitner H (1990) The effect of grenzray therapy on pustulosis palmoplantaris. Acta Dermatol Venereol (Stockh) 70: 529–531

    Google Scholar 

  • Stevens DM, Ackerman BA (1984) On the concept of bacterids (pustular bacterid, Andrews). Am J Dermatopathol 6: 281–286

    Article  PubMed  CAS  Google Scholar 

Erosive Pustular Dermatosis of the Scalp

  • Bieber T, Ruzicka T, Burg G (1987) Erosive pustulöse Dermatitis des Kapillitiums. Hautarzt 38: 687–689

    PubMed  CAS  Google Scholar 

  • Caputo R, Veraldi S (1993) Erosive pustular dermatosis of the scalp. J Am Acad Dermatol 28: 96–98

    Article  PubMed  CAS  Google Scholar 

  • Jacyk WK (1988) Pustular ulcerative dermatosis of the scalp. Br J Dermatol 118: 441–444

    Article  PubMed  CAS  Google Scholar 

  • Pye RJ, Peachey RDG, Burton JL (1979) Erosive pustular dermatosis of the scalp. Br J Dermatol 100: 559–566

    Article  PubMed  CAS  Google Scholar 

  • Watanabe S, Takizawa K, Hashimoto N et al. (1989) Pustular dermatosis of the scalp associated with autoimmune diseases. J Dermatol 16: 383–387

    PubMed  CAS  Google Scholar 

Erythema Toxicum Neonatorum

  • Ferrandiz C, Coroleu W, Ribera M et al. (1992) Sterile transient neonatal pustulosis is a precocious form of erythema toxicum neonatorum. Dermatology 185: 18–22

    Article  PubMed  CAS  Google Scholar 

  • Schwartz RA, Janniger CK (1996) Erythema toxicum neonatorum. Cutis 58: 153–155

    PubMed  CAS  Google Scholar 

Transient Neonatal Pustular Melanosis

  • Hansen LP, Brandrup F, Zori R (1985) Erythema toxicum neonatorum mit Pustulation versus transitonische neonatale pustulöse Melanose. Hautarzt 36: 475–477

    PubMed  CAS  Google Scholar 

  • Ramamurthy RS, Reveri M, Esterly NB et al. (1976) Transient neonatal pustular melanosis. J Pediatr 88: 831–835

    Article  PubMed  CAS  Google Scholar 

  • Wyre HW, Murphy MO (1979) Transient neonatal pustular melanosis. Arch Dermatol 115: 458

    Article  PubMed  Google Scholar 

Transient Cephalic Neonatal Pustulosis

  • Aractingi S, Cadranel S, Reygagne P et al. (1991) Neonatal pustulosis induced by Malassezia furfur. Ann Dermatol Venereol 118: 856–858

    PubMed  CAS  Google Scholar 

  • Bardazzi F, Patrizi A (1997) Transient cephalic neonatal pustulosis. Arch Dermatol 133: 528–530

    Article  PubMed  CAS  Google Scholar 

  • Niamba P, Weill FX, Sarlangue J (1998) Is common neonatal cephalic pustulosis (neonatal acne) triggered by Malassezia sympodialis? Arch Dermatol 134: 995–998

    Article  PubMed  CAS  Google Scholar 

Subcorneal Pustular Dermatosis

  • Bauwens M, De Conick A, Roseeuw D (1999) Subcorneal pustular dermatosis treated with PUVA therapy. A case report and review of the literature. Dermatology 203–205

    Google Scholar 

  • Chimenti S, Ackerman AB (1981) Is subcorneal pustular dermatosis of Sneddon and Wilkinson an entity sui generis? Am J Dermatopathol 3: 363–376

    Article  PubMed  CAS  Google Scholar 

  • Ise S, Ofuji S (1965) Subcorneal pustular dermatosis. A follicular variant? Arch Dermatol 92: 169–171

    Article  Google Scholar 

  • Kasha EE, Epinette WW (1988) Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) in association with a monoclonal IgA-gammopathy: A report and review of the literature. J Am Acad Dermatol 19: 854–858

    Article  PubMed  Google Scholar 

  • Lutz ME, Daoud MS, McEvoy MT et al. (1998) Subcorneal pustular dermatosis: a clinical study of ten patients. Cutis 61: 203–208

    PubMed  CAS  Google Scholar 

  • Sneddon IB, Wilkinson DD (1956) Subcorneal pustular dermatosis. Br J Dermatol 68: 385–394

    Article  PubMed  CAS  Google Scholar 

  • Sneddon IB, Wilkinson DS (1979) Subcorneal pustular dermatosis. Br J Dermatol 100: 61–68

    Article  PubMed  CAS  Google Scholar 

  • Stolz W, Bieber T, Meurer M (1989) Its the atypical neutrophilic dermatosis with subcorneal IgA deposits a variant of pemphigus foliaceus? Br J Dermatol 120: 276–279

    Article  Google Scholar 

Impetigo Herpetiformis

  • Breier-Maly J, Ortel B, Breier F et al. (1999) Generalized pustular psoriasis of pregnancy (impetigo herpetiformis) Dermatology 198: 61–64

    PubMed  CAS  Google Scholar 

  • Hebra F (1872) Über einzelne während der Schwangerschaft, dem Wochenbette, und bei Utermalkrankheiten der Frauen zu beobachtende Hautkrankheiten. Wien Med Wochenschr 48: 1197–1202

    Google Scholar 

  • Kaposi M (1887) Impetigo herpetiformis. Arch Dermatol Syph 19: 273–296

    Google Scholar 

  • Moynihan GD, Ruppe JP (1985) Impetigo herpetiformis and hypoparathyroidism. Arch Dermatol 121: 1330–1331

    Article  PubMed  CAS  Google Scholar 

Acute Generalized Pustulosis

  • Beylot C, Doutre MS, Beylot-Barry M (1996) Acute generalized exanthematous pustulosis. Semin Cut Med Surg 15: 244–249

    Article  CAS  Google Scholar 

  • Braun-Falco O, Luderschmidt C, Maciejewski W et al. (1978) Pustulosis acuta generalisata. Eine ungewöhnliche Erscheinungsform von leukozytoklastischer Vaskulitis. Hautarzt 29: 371–377

    PubMed  CAS  Google Scholar 

  • MacMillan AL (1973) Generalized pustular drug rash. Dermatologica 146: 285–291

    Article  PubMed  CAS  Google Scholar 

  • Roujeau JC, Bioulac-Sage P, Bourseau C et al. (1991) Acute generalized exanthematous pustulosis. Analysis of 60 cases. Arch Dermatol 127: 1333–1338

    Article  PubMed  CAS  Google Scholar 

  • Tan RSH (1974) Acute generalized pustular bacterid. An unusual manifestation of leukocytoclastic vasculitis. Br J Dermatol 91: 209–215

    Article  PubMed  CAS  Google Scholar 

  • Zelickson BD, Muller SA (1991) Generalized pustular psoriasis. A review of 63 cases. Arch Dermatol 127: 1339–1345

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Braun-Falco, O., Plewig, G., Wolff, H.H., Burgdorf, W.H.C. (2000). Pustular Diseases. In: Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97931-6_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-97931-6_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-97933-0

  • Online ISBN: 978-3-642-97931-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics