Zusammenfassung
Die Entwicklung von Hemmstoffen des Angiotensin-I-Konversionsenzyms (ACE/Kininase II) und ihre Einführung in Klinik und Praxis stellen einen Meilenstein in der Ermittlung neuer therapeutischer Wirkprinzipien während der letzten Jahre medizinischer Forschung dar. Dabei ist die Entdeckung dieser Substanzklasse untrennbar verknüpft mit der Erforschung des Renin-Angiotensin-Aldosteron-Systems (RAAS). Tabelle 54.1 zeigt hierzu die wichtigsten historischen Eckdaten.
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Allgeier, J., Hauf, G.F. (1996). ACE-Hemmer. In: Herzkrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97605-6_54
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