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Urtikaria und Nahrungsmittelallergien bzw. -intoleranzen

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Therapie der Hautkrankheiten

Zusammenfassung

Urtikarielle Gewebsreaktionen sind vorwiegend Folge einer IgE-mediierten (sog. „bridging“) histaminabhängigen Vasodilatation, die von einer Erhöhung der Gefäßpermeabilität in der Haut begleitet ist und sich klinisch mit Quaddelbildurig (Ödem) und Juckreiz manifestiert. Im Bereich der Weichteile und der hautnahen Schleimhäute kann es zu massiven Schwellungen kommen. Solche Reaktionen können einmalig akut auftreten und nach wenigen Tagen verschwinden (akute Urtikaria) oder auch über mehrere Jahre persistieren bzw. immer wieder Rückfälle zeigen (chronisch-rezidivierende Urtikaria). Die auslösende Ursache ist sehr unterschiedlich oder bleibt oft ungeklärt. Doch sehr häufig spielen oral eingenommene Noxen, z. B. Nahrungsmittelallergene aber auch Medikamente, eine wichtige Rolle.

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Literatur

  • Abdel-Naser MB, Gollnick H, Orfanos CE (1993) Aquagenic pruritus as a presenting symptom of polycythemia vera. Dermatology 187: 130–133

    Article  PubMed  CAS  Google Scholar 

  • Arendt C, Bernheim I (1989) Double-blind comparison of maintenance of chronic idiopathic urticaria by cetirizine and terfenadine. Curr Res 46: 724–734

    Google Scholar 

  • Asad SI, Kemeny DM, Youlten LJF, Frankland AW, Lessow MH (1984) Effect of aspirin in „aspirin sensitive“ patients. Br Med J 288: 745–748

    Article  CAS  Google Scholar 

  • August PJ, O’Driscoll J (1989) Urticaria successfully treated by desensitization with grass pollen extract. Br J Dermatol 120: 409–410

    Article  PubMed  CAS  Google Scholar 

  • Berchtold E, Maibach R, Muller U (1992) Reduction of side effects from rush-immunotherapy with honey bee venom by pretreatment with terfenadine. Clin Exp Allergy 22: 59–65

    Article  PubMed  CAS  Google Scholar 

  • Bernhard JD, Jaenicke K, Momtaz TK, Parrish JA (1984) Ultraviolet A phototherapy in the prophylaxis of solar urticaria. J Am Acad Dermatol 10: 29–33

    Article  PubMed  CAS  Google Scholar 

  • Bielory L, Lee SS, Holland CL, Jaker M (1992) Long-acting ACE inhibitor-induced angioedema. Allergy Proc 13: 85–87

    Article  PubMed  CAS  Google Scholar 

  • Birgerson L (1991) Tranexamic acid in the treatment of hereditary angioedema (letter). Am J Med 91: 102

    Article  PubMed  CAS  Google Scholar 

  • Bressler RB, Sowell K, Huston DP (1989) Therapy of chronic idiopathic urticaria with nifedipine: Demonstration of beneficial effect in a double-blinded, placebo-controlled, crossover trial. J Allergy Clin Immunol 83: 756–763

    Article  PubMed  CAS  Google Scholar 

  • Canonica GW, Pesce G, Ruffoni S et al. (1992) Cetirizine does not influence the immune response. Ann Allergy 68 (3): 251–254

    PubMed  CAS  Google Scholar 

  • Casale TB, Sampson HA, Hanifin J et al. (1988) Guide to physical urticarias. J Allergy Clin Immunol 82: 758–763

    Article  PubMed  CAS  Google Scholar 

  • Champion RH, Highet AS (1982) Investigation and management of chronic urticaria and angio oedema. Clin Exp Dermatol 7: 291–300

    Article  PubMed  CAS  Google Scholar 

  • Cicardi M, Bergamaschini L, Cugno M, Hack E, Agostoni G, Agostoni A (1991) Long-term treatment of hereditary angioedema with attenuated androgens: a survey of a 13-year experience. J Allergy Clin Immunol 87: 768–773

    Article  PubMed  CAS  Google Scholar 

  • Cirardi M, Bergamaschini L, Marasini B, Boccasini G, Tucci A, Agostoni A (1982) Hereditary angioedema: an appraisal of 104 cases. Am J med Sci 284: 2–9

    Article  Google Scholar 

  • Cox NH, Higgins EM, Farr PM (1989) Terfenadine inhibits itch and weal but not abnormal erythema in physical urticarias. J Am Acad Dermatol 2: 586–587

    Article  Google Scholar 

  • Czarnetzki BM, Breetholt KH, Traupe H (1986) Evidence that water acts as a carrier for an epidermal antigen in auagenic urticaria. J Am Acad Dermatol 15: 623–627

    Article  PubMed  CAS  Google Scholar 

  • Diffey BL, Farr PM (1988) Treatment of solar urticaria with terfenadine 5: 25–29

    CAS  Google Scholar 

  • Diller G, Orfanos CE (1983) Behandlung der idiopathischen Urticaria mit H1 + H2 Antagonisten: Ergebnisse einer Crossover-Doppelblind-Langzeitstudie. Z Hautkr 58: 785–793

    PubMed  CAS  Google Scholar 

  • Donaldson VH, Hess EV, McAdams M (1977) Lupus erythematosus-like disease in three unrelated women with hereditary angioneurotic edema. Ann Intern Med 86: 312–313

    PubMed  CAS  Google Scholar 

  • Duschet P, Leyen P, Schwarz T, Hocker P, Greiter J, Gschnait F (1987) Solar urticaria effective treatment by plasmapheresis. Clin Exp Dermatol 12: 185–188

    Article  PubMed  CAS  Google Scholar 

  • Duschet P, Schwarz T, Gschnait F (1989) Plasmapherese bei Lichturtikaria. Ein rationales Therapiekonzept in Fällen mit nachgewiesenem Serumfaktor. Hautarzt 40: 553–555

    PubMed  CAS  Google Scholar 

  • Eichelberg D (1988) Desensibilisierung („Hardening“) der Wärme-Urticaria. Z Hautkr 63: 385–386

    PubMed  CAS  Google Scholar 

  • Farnam J, Grant JA, Guernsey BG, Jorrizzo JL, Petrusa ER (1984) Successful treatment of chronic idiopathic urticaria and angioedema with cimetidine alone. J Allergy Clin Immunol 73: 842–845

    Article  PubMed  CAS  Google Scholar 

  • Ferguson I, MacDonald KJS, Kenicer KJA (1985) Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria. Br J Clin Pharmacol 20: 639–641

    PubMed  CAS  Google Scholar 

  • Fradin MS, Ellis CN, Goldfarb MT, Voorhees JJ (1991) Oral cyclosporine for severe chronic idiopathic urti-caria and angioedema. J Am Acad Dermatol 25: 1065–1067

    Article  PubMed  CAS  Google Scholar 

  • Fredriksson T, Hersle K, Hjorth N et al. (1986) Terfenadine in chronic urticaria: A comparison with clemastine and placebo. Cutis 35: 128–130

    Google Scholar 

  • Göhring HD, Späth P (1992) Erfahrungen in der Therapie des hereditären Angioödems. Dermatol Monatsschr 178: 116–120

    Google Scholar 

  • Grattan CEH, Francis DM, Slater NGP et al. (1992) Plasmapheresis for severe unremitting, chronic urti-caria. Lancet 339: 1078–1080

    Article  PubMed  CAS  Google Scholar 

  • Grassegger A, Greil R, Feichtinger J, Fritsch P, Hintner H (1990) Urtikarielle Vaskulitis als Symptom des Muckle-Wells-Syndroms? Hautarzt 42: 116–119

    Google Scholar 

  • Greaves M, Lawlor F (1991) Angioedema: manifestations and management. J Am Acad Dermatol 25: 155–161

    Article  PubMed  CAS  Google Scholar 

  • Greene SP, Reed CE, Schroeter AL (1985) Double-blind crossover study comparing doxepin with diphenhydramine for the treatment of chronic urti-caria. J Am Acad Dermatol 12: 669–675

    Article  PubMed  CAS  Google Scholar 

  • Grzelewska-Rzymowska I, Roznlecki J, Szmidt M (1988) Aspirin „desensitization“ in patients with aspirin-induced urticaria and angioedema. Allergol Immunopathol (Madr) 16: 305–308

    CAS  Google Scholar 

  • Häberle M (1987) Salicylate und biogene Amine — natürliche Inhaltsstoffe von Nahrungsmitteln als Auslöser von Pseudoallergien. Ernährungs-Umschau 34: 287–296

    Google Scholar 

  • Harto A, Sendagorta E, Ledo A (1985) Doxepin in the treatment of chronic urticaria. Dermatologica 170: 90–93

    Article  PubMed  CAS  Google Scholar 

  • Henquet CJM, Martens BPM, van Vloten WA (1992) Cold urticaria: a clinico-therapeutic study in 30 patients with special emphasis on cold desensitization. Eur J Dermatol 2: 75–77

    Google Scholar 

  • Hopfl R, Schwarz S, Fritsch P, Hintner H (1990) Danazol-Langzeittherapie bei hereditärem Angioödem. Dtsch Med Wochenschr 115: 133–138

    Article  PubMed  CAS  Google Scholar 

  • Horio T, Yoshioka A, Okamoto H (1984) Production and inhibition of solar urticaria by visible light exposure. J Am Acad Dermatol 11: 1094–1099

    Article  PubMed  CAS  Google Scholar 

  • Huerter CJ, Bergfeld WF, Wagner WO, Dijkstra JWE (1989) Treatment of chronic idiopathic urticaria with astemizole. Cleve Clin J Med 56: 263–266

    PubMed  CAS  Google Scholar 

  • Husz S, Toth-Kasa I, Kiss M, Dobozy A (1994) Treatment of cold urticaria. Intern J Dermatol 33: 210–213

    CAS  Google Scholar 

  • Ichihashi M, Hasei K, Hayashibe K (1985) Solar urti-caria: Further studies on the role of inhibition spectra. Arch Dermatol 121: 503–507

    Article  PubMed  CAS  Google Scholar 

  • Illig L, Paul E (1983) Nahrungsmittel-bedingte und pseudoallergische Reaktionen an der Haut und Schleimhaut mit besonderer Berücksichtigung der nahrungsmittelbedingten Urtikaria und RAST. Z Hautkr 59: 793–813

    Google Scholar 

  • Israili ZH, Hall WD (1992) Cough and angioneurotic edema associated with angiotensin-converting enzyme inhibitor therapy. A review of the literature and pathophysiology. Ann Intern Med 117: 234–242

    PubMed  CAS  Google Scholar 

  • Johnsson M, Falk ES, Volden G (1987) UVB treatment of factitious urticaria. Photodermatol 4: 302–304

    PubMed  CAS  Google Scholar 

  • Juhlin L, Arendt C (1988) Treatment of chronic urti-caria with cetirizine dihydrochloride, a non-sedative antihistamine. Br J Dermatol 119: 67–72

    Article  PubMed  CAS  Google Scholar 

  • Juhlin L, Malmros-Enander I (1986) Solar urticaria: mechanism and treatment. Photodermatol 3: 164–168

    PubMed  CAS  Google Scholar 

  • Kailasam V, Mathews KP (1987) Controlled clinical assessment of astemizole in the treatment of chronic idiopathic urticaria and angioedema. J Am Acad Dermatol 16: 797–804

    Article  PubMed  CAS  Google Scholar 

  • Kamide R, Niimura M, Ueda H, Imamura S, Yamamoto S, Yoshida H, Kukita A (1989) Clinical evaluation of ketotifen for chronic urticaria: multicenter double-blind comparative study with clemastine. Ann Allergy 62: 322–325

    PubMed  CAS  Google Scholar 

  • Kavanagel GM, Sansom JE, Harrison P et al. (1993) Tranexamic acid (Cyklokapron®) induced fixed drug eruption. Br J Dermatol 128: 229–230

    Article  Google Scholar 

  • Kaur S, Greaves M, Eftekhavi N (1981) Factitious urti-caria (dermographism): Treatment by cimetidine and chlorpheniramine in a randomized double-blind study. Br J Dermatol 104: 185–190

    Article  PubMed  CAS  Google Scholar 

  • Keahey TM, Indrisano J, Kaliner MA (1988) A case study on the induction of clinical tolerance in cold urticaria. J Allergy Clin Immunol 82: 256–261

    Article  PubMed  CAS  Google Scholar 

  • Krause LB, Shuster S (1985) A comparison of astemizole and chlorpheniramine in dermographic urti-caria. Br J Dermatol 112: 447–453

    Article  PubMed  CAS  Google Scholar 

  • Kulczycki A (1986) Aspartame-induced urticaria. Ann Intern Md 104: 207–208

    Google Scholar 

  • Lawlor F, Greaves MW (1990) Die Entwicklung neuer Strategien der Urtikariatherapie als ein Ergebnis klinisch orientierter Forschung. Z Hautkr 65: 17–27

    PubMed  CAS  Google Scholar 

  • Ledo E (1993) Photodermatosis. Part I: Photobiology, photoimmunology, and idiopathic photodermatoses. Int J Dermatol 32: 387–396

    Article  PubMed  CAS  Google Scholar 

  • Leenutaphong V, Hoelzle E, Plewig G, Grabensee B, Kutkuhn B (1987) Plasmapheresis in solar urticaria. Photodermatol 4: 308–309

    PubMed  CAS  Google Scholar 

  • Leenutaphong V, von Kries R, Hoelzle E, Plewig G (1988) Solar urticaria induced by visible light and inhibited by UVA. Photodermatol 5: 170–174

    PubMed  CAS  Google Scholar 

  • Legrain V, Taieb A, Sage T, Maleville J (1990) Urticaria in infants: a study of forty patients. Pediatr Dermatol 7: 101–107

    Article  PubMed  CAS  Google Scholar 

  • Lindelöf B, Sigurgeirsson B, Wahlgren CF, Eklund G (1990) Chronic urticaria and cancer: an epidemiological study of 1155 patients. Br J Dermatol 123: 453–456

    Article  PubMed  Google Scholar 

  • Logan RA, O’Brien TJ, Greaves MW (1989) The effect of psoralen photochemotherapy ( PUVA) on symptomatic dermographism. Clin Exp Dermatol 14: 25–28

    Article  PubMed  CAS  Google Scholar 

  • Mehregan DR, Hall MJ, Gibson LE (1992) Urticarial vasculitis: a histopathologic and clinical review of 72 cases. J Am Acad Dermatol 26: 441–448

    Article  PubMed  CAS  Google Scholar 

  • Millns JL, Randle HW, Solley GO, Dicken CH (1980) The therapeutic response of urticarial vasculitis to indomethacin. J Am Acad Dermatol 3: 349–355

    Article  PubMed  CAS  Google Scholar 

  • Monroe EW, Cohen SH, Kalbfleisch J, Schulz CI (1981) Combined H1 and H2 antihistamine therapy in chronic urticaria. Arch Dermatol 117: 404–407

    Article  PubMed  CAS  Google Scholar 

  • Neittaanmaki H, Myohanen T, Fraki JE (1984) Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: Usefulness of doxepin. J Am Acad Dermatol 11: 483–489

    Article  PubMed  CAS  Google Scholar 

  • Olafsson JH, Larko O, Roupe G, Granerus G, Bengtsson U (1986) Treatment of chronic urticria with PUVA or UVA plus placebo: a double-blind study. Arch Dermatol Res 278: 228–231

    Article  PubMed  CAS  Google Scholar 

  • Parrish JA, Jaenicke KF, Morison WL, Momtaz K, Shea C (1982) Solar urticaria: Treatment with PUVA and mediator inhibitors. Br J Dermatol 106: 575–580

    Article  PubMed  CAS  Google Scholar 

  • Paul E, Bödeker R (1989) Comparative study of astemizole and terfenadine in the treatment of chronic idiopathic urticaria: a randomized double-blind-study of 40 patients. Ann Allergy 62: 318–320

    PubMed  CAS  Google Scholar 

  • Rajatanavin N, Bernhard JD (1988) Solar urticaria: treatment with terfenadine (letter). J Am Acad Dermatol 18: 574

    Article  PubMed  CAS  Google Scholar 

  • Ring I (1989) Pseudo-allergische Reaktionen durch Nahrungsmittel und Zusatzstoffe. Allergologie 12: 165–168

    Google Scholar 

  • Ring I, Braun-Falco O (1987) Allergie-Diät: Verfahren zur Diagnostik und Therapie von Nahrungsmittelallergien und -Pseudoallergien. Hautarzt 38: 198–205

    PubMed  CAS  Google Scholar 

  • Saihan EM (1981) Ketotifen and terbutaline in urti-caria. Br J Dermatol 104: 205–206

    PubMed  CAS  Google Scholar 

  • Schwegler F, Marsch WC (1992) Doxepin-Therapie bei Kältereflexurtikaria vom Soforttyp. Dermatol Monatsschr 178: 262–263

    Google Scholar 

  • Settipane GA (1984) Adverse reactions to sulfites in drugs and foods. J Amer Acad Dermatol 10: 1077–1080

    Article  CAS  Google Scholar 

  • Sheffer AL, Horan RF (1989) Current concepts of urti-caria and angioedema. Allergy Proc 10: 237–41

    Article  PubMed  CAS  Google Scholar 

  • Shelley WB, Shelley ED (1985) Adrenergic urticaria: A new form of stress-induced hives. Lancet 2: 1031–1033

    Article  PubMed  CAS  Google Scholar 

  • Shertzer CL, Lookingbill DP (1987) Effects of relaxation therapy and hypnotizability in chronic urticaria. Arch Dermatol 123: 913–916

    Article  PubMed  CAS  Google Scholar 

  • Simons FE, Simons KJ, Frith EM (1984) The pharmacokinetics and antihistaminic action of the H1 receptor antagonist hydroxyzine. J Allergy Clin Immunol 73: 69–75

    Article  PubMed  CAS  Google Scholar 

  • Soter NA (1991) Treatment of urticaria and angioedema: low-sedating H1-type antihistamines. J Am Acad Dermatol 24: 1084–1087

    Article  PubMed  CAS  Google Scholar 

  • Stafford CT (1990) Urticaria as a sign of systemic disease. Ann Allergy 64: 264–270

    PubMed  CAS  Google Scholar 

  • Steinman HK, Greaves MW (1985) Aquagenic pruritus. J Am Acad Dermatol 13: 91–96

    Article  PubMed  CAS  Google Scholar 

  • Stephansson E, Koskimies S, Lokki ML (1991) Exercise-induced urticaria and anaphylaxis. Acta Derm Venerol (Stockh) 71: 138–142

    CAS  Google Scholar 

  • Tatnall FM, Gaylarde PM, Sarkany I (1984) Localised heat urticaria and its management. Clin Exp Dermatol 9: 367–374

    Article  PubMed  CAS  Google Scholar 

  • Thormann J, Laurberg G, Zachariae H (1980) Oral sodium cromoglycate in chronic urticaria. Allergy 35: 139–141

    Article  PubMed  CAS  Google Scholar 

  • Twarog FJ (1983) Urticaria in childhood: pathogenesis and management. Pediatr Clin North Am 30: 887–898

    PubMed  CAS  Google Scholar 

  • Ulmer JL, Garvey MJ (1992) Fatal angioedema associated with lisinopril. Ann Pharmacother 26: 1245–1246

    PubMed  CAS  Google Scholar 

  • Veronesi S, Palmerio B, Negosanti M, Tosti A (1983) Urticaria and giardiasis. Dermatologica 166: 42–43

    Article  PubMed  CAS  Google Scholar 

  • Verschave A, Stevens E, Degreef H (1983) Pseudo-allergenfree diet in chronic urticaria. Dermatologica 167: 256–259

    Article  PubMed  CAS  Google Scholar 

  • Wanderer AA (1990) Cold urticaria syndromes: historical background, diagnostic classification, clinical and laboratory characteristics, pathogenesis, and management. J Allergy Clin Immunol 85: 965–981

    Article  PubMed  CAS  Google Scholar 

  • Wantke F, Götz M, Jarisch R (1993) Die histaminfreie Diät. Hautarzt 44: 512–516

    PubMed  CAS  Google Scholar 

  • Warin RP (1989) Clinical observations on delayed pressure urticaria. Br J Dermatol 121: 225–228

    Article  PubMed  CAS  Google Scholar 

  • Werner RJ, Marsch WC (1992) Therapie einer Druckurtikaria vom verzögerten Typ mit Cetirizin. Dermatol Monatsschr 178: 187–190

    Google Scholar 

  • Widmer M, Späth P, Wüthrich B (1989) Hereditäres Angioödem (HAO): Substitutionstherapie mit C1Inhibitor-Konzentrat zur Intervallbehandlung. Allergologie 12: 432–439

    Google Scholar 

  • Wolf C, Pehamberger H, Breyer S, Leiferman KM, Wolff K (1989) Episodic angioedema with eosinophilia. J Am Acad Dermatol 20: 21–27

    Article  PubMed  CAS  Google Scholar 

  • Wüthrich B (1990) Gibt es Nahrungsmittelallergien vom Typ III? Allergologie 13: 371–375

    Google Scholar 

  • Zurlo JJ, Frank MM (1990) The long-term safety of danazol in women with hereditary angioedema. Fertil Steril 54: 64–72

    PubMed  CAS  Google Scholar 

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Orfanos, C.E., Garbe, C. (1995). Urtikaria und Nahrungsmittelallergien bzw. -intoleranzen. In: Therapie der Hautkrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97602-5_15

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