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General Fundamentals

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Contrast Media in Practice

Abstract

In diagnostic imaging, a distinction is made between negative X-ray (air, O2,CO2), positive X-ray (barium BaSO4; iodine, I), paramagnetic, and ultraso-nographic contrast media (CM). Barium sulphate (BaSO4) had already been used in 1896 for investigations on peristalsis, but it was forgotten again once the study was concluded. It was only about a decade later that BaSO4, “newly” developed by the pharmacist and final-year medical student Fritz Munk, was introduced into X-ray investigations of the gastrointestinal tract as the so-called Rieder meal (barium mixed with gruel). It has been able to maintain its predominant position up to the present day, albeit with certain modifications such as taste corrigents and changes in density and particle size, though occasionally it is replaced by tri-iodinated ionic or nonionic X-ray CM, which are used, for example, in suspected fistulae, ileus, or for an array of purposes in children.

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Maurer, H.J. et al. (1993). General Fundamentals. In: Dawson, P., Clauß, W. (eds) Contrast Media in Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97530-1_1

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