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Liver Xenotransplantation: Clinical Experience and Future Considerations

  • D. V. Cramer
  • L. Sher
  • L. Makowka

Abstract

The use of xenografts in liver transplantation offers several distinct advantages for the treatment of patients with end-stage liver disease and fulminant liver failure. The first is the availabihty of a predictable and ready supply of donor organs. At the present time the most critical element restricting the widespread apphcation of liver transplantation as a therapeutic modality is the shortage of human donor organs. It has been estimated that approximately 20%–25% of patients awaiting liver transplantation die due to lack of an appropriate donor organ. The limited supply of donor organs also has the effect of limiting the size of the potential pool of recipients that may benefit from the procedure. An increased supply of suitable organs will result in a large increase in the number of transplants performed.

Keywords

Donor Organ Biliary Atresia Natural Antibody Acute Hepatic Failure Hyperacute Rejection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • D. V. Cramer
  • L. Sher
  • L. Makowka

There are no affiliations available

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