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Experimental Xenotransplantation Between Closely Related Primate Species

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Xenotransplantation

Abstract

The current success of clinical solid organ transplantation has resulted in a shortage of suitable donors; this is particularly true for intrathoracic organs. This shortage has prompted many to consider the use of nonhuman organs for transplantation in man. In order to minimize the vigorous immunological responses that have been observed in experimental xenotransplantation, investigators have studied transplantation between phylogenetically closely related animal models. This has resulted in an increased understanding of the mechanisms of rejection and has also led to the development of models in which immunomodulative strategies are tested prior to their use in human allotransplantation.

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Authors
  1. J. A. Sanchez
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  2. R. E. Michler
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  3. E. A. Rose
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  4. D. K. C. Cooper
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Editor information

Editors and Affiliations

  1. Baptist Medical Center, Oklahoma Transplantation Institute, 3300 N. W. Expressway, 73112, Oklahoma City, OK, USA

    D. K. C. Cooper M. D. Ph. D.

  2. Department of Nephrology, Odense University Hospital, DK-5000, Odense, Denmark

    Ejvind Kemp M. D.

  3. Department of Surgery, Columbia-Presbyterian Medical Center, 622 West 168th Street, 10032, New York, NY, USA

    Keith Reemtsma M. D.

  4. Department of Surgery, Addenbrooke’s Hospital, Hills Road, CB2 2QQ, Cambridge, UK

    D. J. G. White Ph. D., MRC Path.

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© 1991 Springer-Verlag Berlin Heidelberg

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Sanchez, J.A., Michler, R.E., Rose, E.A., Cooper, D.K.C. (1991). Experimental Xenotransplantation Between Closely Related Primate Species. In: Cooper, D.K.C., Kemp, E., Reemtsma, K., White, D.J.G. (eds) Xenotransplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97323-9_22

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  • DOI: https://doi.org/10.1007/978-3-642-97323-9_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-97325-3

  • Online ISBN: 978-3-642-97323-9

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