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Experimental Xenotransplantation Between Closely Related Nonprimate Species

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Book cover Xenotransplantation

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Abstract

For almost a century it has been man’s dream to replace diseased organs in end-stage patients by using xenogeneic grafts. Systematic immunological, biochemical, and physiological studies in this context have demonstrated that evolutionary and zoological factors would limit both the supply of suitable organs and the success rate following transplantation. Organs appropriate in size and availabihty are a prerequisite for the successful outcome of clinical xenogeneic organ transplantation. However, not many animal species exist worldwide where the numbers are abundant enough to serve as general organ donors. Only farm animals hke the pig, sheep, goat, and small equine and bovine breeds would be readily available.

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Authors
  1. C. Hammer
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Editor information

Editors and Affiliations

  1. Baptist Medical Center, Oklahoma Transplantation Institute, 3300 N. W. Expressway, 73112, Oklahoma City, OK, USA

    D. K. C. Cooper M. D. Ph. D.

  2. Department of Nephrology, Odense University Hospital, DK-5000, Odense, Denmark

    Ejvind Kemp M. D.

  3. Department of Surgery, Columbia-Presbyterian Medical Center, 622 West 168th Street, 10032, New York, NY, USA

    Keith Reemtsma M. D.

  4. Department of Surgery, Addenbrooke’s Hospital, Hills Road, CB2 2QQ, Cambridge, UK

    D. J. G. White Ph. D., MRC Path.

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© 1991 Springer-Verlag Berlin Heidelberg

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Hammer, C. (1991). Experimental Xenotransplantation Between Closely Related Nonprimate Species. In: Cooper, D.K.C., Kemp, E., Reemtsma, K., White, D.J.G. (eds) Xenotransplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97323-9_21

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  • DOI: https://doi.org/10.1007/978-3-642-97323-9_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-97325-3

  • Online ISBN: 978-3-642-97323-9

  • eBook Packages: Springer Book Archive

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