Abstract
At present, short-term success has been obtained with isolated pancreas islet allografts [1,2]. Clinical success has not been obtained with islet xenografts, although at least one study suggest that the human immune response to islet xenografts may be no stronger than that to allografts in some instances [3]. Recent advances in both islet isolation techniques and suppression of xenogeneic immune reactivity have provided a measure of optimism regarding the future of islet xenografting which was not previously appropriate.
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References
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Thomas, F.T. (1991). Isolated Pancreas Islet Xenografting. In: Cooper, D.K.C., Kemp, E., Reemtsma, K., White, D.J.G. (eds) Xenotransplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97323-9_16
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