Abstract
Following the NIH Consensus Development Conference Statement [1], worldwide interest in liver transplantation has increased dramatically. Recent published figures suggest that about 2000 grafts have been performed in North America [2] and over 1200 in 32 centers in Europe [3], with the current rate probably about 5 per million population in 69 centers in Europe and 9 per million in 66 centers in the USA. Transplant programs have also commenced in Australia [4], and parts of Eastern Europe and South America so that the total world experience may weh have already exceeded 10 000 cases. This huge increase in demand, in the face of a finite supply of human donor organs, is one of the main reasons for a renewed interest in xenografts.
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References
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Wight, D.G.D. (1991). Histopathology of Liver Xenograft Rejection. In: Cooper, D.K.C., Kemp, E., Reemtsma, K., White, D.J.G. (eds) Xenotransplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97323-9_15
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