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The Kiel Classification

  • Karl Lennert
  • Alfred Christian Feller

Abstract

The old simple classification19 used in Germany until the introduction of the Kiel classification differed from the classification recommended by Rappaport,20 which has been widely accepted in Western countries because of its apparent clinical relevance. Since neither the old German classification nor Rappaport’s classification is compatible with the knowledge gained from modern research in immunology, it was clearly necessary to apply the results of this research to neoplasms of lymphocytes and their variants. This required taking three steps: (1) the various cell types of lymphoid tissue (and lymphoid neoplasms) had to be defined by haematological and cytochemical methods; (2) the immunological characteristics (“markers”) of the morphologically identified cells had to be determined; and (3) lymphoma cells had to be morphologically and immunologically matched with their normal counterparts. These investigations led to a new understanding of ML. By taking the criteria of general pathology and haematology and the clinical behaviour of ML into consideration, it was then possible to propose a new classification. The so-called Kiel classification21 (Table 6) is based on that proposition.

Keywords

Germinal Centre Mycosis Fungoides Working Formulation Lymphoblastic Lymphoma Immunoblastic Lymphoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Karl Lennert
    • 1
  • Alfred Christian Feller
    • 2
  1. 1.Zentrum für Pathologie und angewandte KrebsforschungKielGermany
  2. 2.Pathologisches InstitutUniversität Würzburg, LuitpoldkrankenhausWürzburgGermany

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