Zusammenfassung
Zum Verständnis der Pharmakoptherapie bei Herzinsuffizienz sei an zwei hämodynamische Besonderheiten des insuffizienten linken Ventrikels erinnert:
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Die Ventrikelfunktionskurve verläuft abnorm: sie ist abgeflacht, erreicht ihr Maximum bei höheren Füllungsdrücken und fällt bei weiterer Steigerung des Füllungsdruckes möglicherweise wieder ab.
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Die Förderleistung des Herzens hängt in starkem Maße vom peripheren Gefäßwiderstand ab.
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Schuster, H.P. (1993). Vasodilatatoren und positiv-inotrope Pharmaka. In: Benzer, H., Burchardi, H., Larsen, R., Suter, P.M. (eds) Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97183-9_32
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