Immunosuppression, Lupus Nephritis, Multiple Sclerosis, and Organ Transplantation

Part of the Medical Radiology book series (MEDRAD)


The current use of Total Lymphoid Irradiation (TLI) as immunosuppressive therapy for non-malignant diseases is experimental and has been utilized (1) in preparation for allogeneic organ transplantation (i.e., kidney, pancreas, etc.; 26% of radiation oncologists in the national survey would not treat), (2) in the treatment of autoimmune diseases (i.e., rheumatoid arthritis, systemic lupus erythematosus, etc.; 94% of radiation oncologists in the national survey would not treat), and (3) in the treatment of neurological disorders considered to have an immune-mediated pathogenesis (i.e., multiple sclerosis, chronic demyelinating polyneuropathy, etc.; 93% of radiation oncologists in our national survey would not treat).


Multiple Sclerosis Lupus Nephritis Acute Rejection Total Body Irradiation Subacute Thyroiditis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  1. 1.The Johns Hopkins HospitalBaltimoreUSA
  2. 2.School of MedicineStanford UniversityStanfordUSA

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