Desmoid-Aggressive Fibromatosis

Part of the Medical Radiology book series (MEDRAD)


Following surgical excision alone, local recurrences occur in 27–57 percent of cases of desmoid — aggressive fibromatosis. Radiation therapy in doses of 5000–6000 rad decreases local recurrence rates. Normal tissue tolerance may be limiting for the total dose of external beam radiation; therefore either post-operative brachytherapy or brachytherapy following external beam may be used. Regression rates may occur from eight months to two years following treatment. Desmoid — aggressive fibromatosis may occur in association with Gardner’s syndrome and pregnancy. A seventy percent local control rate has been reported with external radiation. In the national survey eighty-two percent of radiation oncologists would treat desmoid — aggressive fibromatosis.


Desmoid Tumor Cystic Hygroma Aggressive Fibromatosis Normal Tissue Tolerance Roentgen Therapy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  1. 1.The Johns Hopkins HospitalBaltimoreUSA
  2. 2.School of MedicineStanford UniversityStanfordUSA

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