Bowen’s Disease

Part of the Medical Radiology book series (MEDRAD)


Bowens’ disease is often described as an intraepithelial carcinoma. There are so many methods of treating the disease that in our reference out of 125 verified lesions, only 19 were treated with grenz rays. We conclude that alternate methods of therapy are the treatment methods of choice. Fifty-three percent of radiation oncologists would not treat Bowen’s disease according to the national survey.


Adenoid Cystic Carcinoma Osmic Acid Bronchial Carcinoid Calcific Tendinitis Persistent Synovitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Blank AA and Schnyder VW (1985) Soft x-ray therapy in Bowen’s disease and erythroplasia of Queyrat. Dermatologica 171: 89–94.PubMedCrossRefGoogle Scholar
  2. 2.
    Stevens DM, Kopf AW, Gladstein A and Bart RS (1977) Treatment of Bowen’s disease with grenz rays. Int J Dermatol 16: 329–339.PubMedCrossRefGoogle Scholar
  3. 3.
    Scoma JA and Levy El (1975) Bowen’s disease of the anus: Report of two cases. Dis Colon & Rectum 18: 137–140.CrossRefGoogle Scholar
  4. 4.
    Hausmen JE (1974) Cryotherapy for treatment of intra-oral leukoplakia and the morbus Bowen. Minerva Medica 65: 3715–3717.Google Scholar
  5. 5.
    Mikhail GR (1974) Bowen’s disease and squamous cell carcinoma of the nail bed. Arch Derm 110: 267–270.PubMedCrossRefGoogle Scholar
  6. 6.
    Wagers LT, Shapiro L and Kroll JJ (1973) Bowen’s disease of the hand. Arch Derm 107: 745–746.PubMedCrossRefGoogle Scholar
  7. 7.
    Sharma K and Majumdar M (1972) Invasive Bowen’s disease. Med J Aust 1: 376–377.PubMedGoogle Scholar
  8. 8.
    Bensaude A and Parturier-Albot M (1971) Anal localization of Bowen’s disease. Proc Roy Soc Med 64: 1190–1191.PubMedGoogle Scholar
  9. 9.
    Lloyd KM (1970) Multicentric pigmented Bowen’s disease of the groin. Arch Denn 101: 48–51.CrossRefGoogle Scholar
  10. 10.
    Yaffee HS (1970) Renal vasculitis and Bowen’s disease. Arch Derm 101: 372–373.PubMedCrossRefGoogle Scholar
  11. 11.
    Fulton JE, Caeter DM and Hurley HJ (1968) Treatment of Bowen’s disease with topical 5-fluorouracil under occlusion. Arch Derm 97: 178–180.PubMedCrossRefGoogle Scholar
  12. 12.
    Janson GT, Dillaha CJ and Honecutt WM (1967) Bowenoid conditions of the skin: Treatment with topical 5-fluorouracil. Southern Med J 60: 185–188.CrossRefGoogle Scholar
  13. 13.
    Edwards M (1965) Bowen’s disease: A case report. Dis Colon & Rectum 8: 297–299.CrossRefGoogle Scholar
  14. 14.
    Michaelides P and Hyman AB (1964) Bowen’s disease of the palm. Report of a case. Dermatologica 128: 239–244.PubMedCrossRefGoogle Scholar
  15. 15.
    Graham JH and Helwig EB (1959) Bowen’s disease and its relationship to systemic cancer. Arch Derm 80: 133–159.CrossRefGoogle Scholar
  16. 1.
    Boedker A and Hald A (1982) A method for selective endobronchial and endotracheal irradiation. J Thorac Cardiovasc Surg 84: 59–61.PubMedGoogle Scholar
  17. 2.
    Aberg T, Blondal T, Nou E, et al (1981) The choice of operation for bronchial carcinoids. Ann Thorac Surg 1: 19–22.CrossRefGoogle Scholar
  18. 3.
    Price JC Lt Col, Percarpio B, Murphy PW, et al (1979) Recurrent adenoid cystic carcinoma of the trachea: Intra-luminal radiotherapy. Otolaryngol Head Neck Surg 5: 614–623.Google Scholar
  19. 4.
    Rowe LD and Jafek BW (1979) Bronchial adenoma: A malignant misnomer. The Laryngoscope 12: 1991–1999.Google Scholar
  20. 5.
    deGruneck JM and Naef AP (1977) Adenomas bronchiques. Schweiz Med Worchenschr 107: 259–266.Google Scholar
  21. 6.
    Marks C and Marks M (1977) Bronchial adenoma. Chest 3: 376–380.CrossRefGoogle Scholar
  22. 7.
    Goldstraw P, Lamb D, McCormack RJM and Walbaum PR (1976) The malignancy of bronchial adenoma. J Thorac Cardiovasc Surg 72: 309.PubMedGoogle Scholar
  23. 8.
    Simpson JA, Smith F, Mutz LR and Hodge AJ (1974) Bronchial adenoma: A review of 26 cases. Aust & New Zealand J Surg 44: 10–116.Google Scholar
  24. 9.
    Walker C (1974) Bilateral choroidal metastases from “adenoma: of bronchus.” Br J Opth 58: 625–629.CrossRefGoogle Scholar
  25. 10.
    Burchart F and Axelsson C (1972) Bronchial adenomas. Thorax 27: 442–449.CrossRefGoogle Scholar
  26. 11.
    Tolis GA, Fry WA, Head L and Shields TW (1972) Bronchial adenomas. Surg Gynec & Obstet 134: 605–610.Google Scholar
  27. 12.
    Turnbull AD, Huvos AG, Doodner JT and Beattie, EJ (1972) The malignant potential of bronchial adenoma. Ann Thoracic Surg 14: 453–464.CrossRefGoogle Scholar
  28. 13.
    Meffert WG and Lindskog GE (1970) Bronchial adenoma. J Thoracic and Cardiovasc Surg 59: 588–602.Google Scholar
  29. 14.
    O’Grady WP, McDivitt RW, Holman CW and Moore SW (1970) Bronchial adenomas. Arch Surg 101: 558–561.PubMedCrossRefGoogle Scholar
  30. 15.
    Smith RA (1969) Bronchial carcinoid tumors. Thorax 24: 43–50.PubMedCrossRefGoogle Scholar
  31. 16.
    Donahue JK, Weichert RF and Ochsner JL (1968) Bronchial adenoma. Ann Surg 167: 873–885.PubMedCrossRefGoogle Scholar
  32. 17.
    Baldwin JN and Grimes OF (1967) Bronchial adenomas. Surg Gynec Obstet 124: 813–818.PubMedGoogle Scholar
  33. 18.
    Brindley Jr GV and Bannet JD (1967) Bronchial adenoma and the carcinoid syndrome. Ann Surg 165: 670–680.PubMedCrossRefGoogle Scholar
  34. 19.
    Batson JF, Gale JW and Hickey RC (1966) Bronchial adenomata. Arch Surg 92: 623–630.PubMedCrossRefGoogle Scholar
  35. 20.
    Reichle FA and Rosemond GP (1966) Mucoepidermoid tumors of the bronchus. J Thoracic and Cardiovas Surg 51: 443–448.Google Scholar
  36. 21.
    Bower G (1965) Bronchial adenoma. Am Rev Resp Dis 92: 558–563.PubMedGoogle Scholar
  37. 22.
    Markel SF and Abell MR (1964) Adenocystic basal cell carcinoma of the trachea. J Thoracic & Cardiovas Surg 48: 211–225.Google Scholar
  38. 23.
    Markel SF, Abell MR, Haight C and French AJ (1964) Neoplasms of bronchus commonly designated as adenomas. Cancer 17: 590–608.PubMedCrossRefGoogle Scholar
  39. 24.
    Wilkins EW, Darling RC, Soitter L and Sniften RC (1963) A continuing clinical survey of adenomas of the trachea and bronchus in a general hospital. J Thoracic & Cardiovasc Surg 46: 279–291.Google Scholar
  40. 25.
    Zellos S (1962) Bronchial adenoma. Thorax 17: 61–68.PubMedCrossRefGoogle Scholar
  41. 26.
    Goodner JT, Berg JW and Watson WL (1961) The nonbenign nature of bronchial carcinoids and cylindromas. Cancer 14: 539–546.PubMedCrossRefGoogle Scholar
  42. 27.
    Weisel W, Lepley Jr D and Watson RR (1961) Respiratory tract adenomas: A ten year survey. Ann Surg 154: 898–902.PubMedGoogle Scholar
  43. 28.
    Weiss L and Ingram M (1961) Adenomatoid bronchial tumors. Cancer 14: 161–178.PubMedCrossRefGoogle Scholar
  44. 29.
    Payne WS, Ellis FH, Woolner LB and Moersch HJ (1959) The surgical treatment of cylindroma (adenoid cystic carcinoma) and mucoepidermoid tumors of the bronchus. J Thorac Cardiovasc Surg 38: 709.PubMedGoogle Scholar
  45. 30.
    Vieta, JO and Maier HC (1957) The treatment of adenoid cystic carcinoma (cylindroma) of the respiratory tract by surgery and radiation therapy. Dis Chest 31: 493–511.PubMedGoogle Scholar
  46. 31.
    Ricketts MM, Price T and Thomas M (1955) Choroidal metastasis of bronchial adenoma. Am J Opth 39: 33–36.Google Scholar
  47. 32.
    Muller H, Quoted R, Engelbreth-Holm J (1945) Benign bronchial adenomas, Acta Chir Scand 90: 383.Google Scholar
  48. 1.
    Milone FP and Copeland MM (1961) Calcific tendinitis of the shoulder joint. Am J Roent Rad Ther Nucl Med 85: 901–913.Google Scholar
  49. 2.
    Amer O, Lindvall N and Rieger A (1958) Calcific tendinitis (tendinitis calcarea) of the shoulder joint. Acta Chir Scand 114: 319–331.Google Scholar
  50. 3.
    Schoss M and Otto TG (1955) Roentgen therapy of sub-deltoid tendinitis and bursitis. Missouri Med 52: 855–863.Google Scholar
  51. 4.
    King JC and Mahaffey CK (1953) Bursitis and peritendinitis: the diagnosis and treatment. South Med J 56: 469–474.CrossRefGoogle Scholar
  52. 5.
    Garber RL (1952) Some observations on roentgen therapy of bursitis and peritendinitis calcarea of the shoulder. Ohio State Med J 48: 918–919.Google Scholar
  53. 6.
    Kratzman EA and Frankel RS (1952) Roentgen therapy of peritendinitis calcarea of the shoulder. Radiology 59: 826–830.PubMedGoogle Scholar
  54. 7.
    Mann LS (1952) Treatment of subdeltoid bursitis with roentgen therapy. J Int Coll Surg 18: 385–388.PubMedGoogle Scholar
  55. 8.
    Plenk HP (1952) Calcifying tendinitis of the shoulder. Radiology 59: 384–389.PubMedGoogle Scholar
  56. 9.
    Steen OT and McCullough JAL (1951) Supraspinatus tendinitis. Am J Roent Rad Ther Nucl Med 65: 245–254.Google Scholar
  57. 10.
    Witt CM and Titterington PF (1951) Roentgen therapy in bursitis of the shoulder. J Missouri Med Assoc 48: 870–873.Google Scholar
  58. 11.
    O’Brien FW (1950) Roentgen therapy and the relief of pain. Radiology 54: 1–9.PubMedGoogle Scholar
  59. 12.
    Lattomus WW and Hunter LM (1949) Roentgen therapy of subdeltoid bursitis. Delaware State Med J 21: 115–117.Google Scholar
  60. 13.
    Hodges FM and Boyer RA (1948) Roentgen therapy of bursitis. Virginia Med Monthly 75: 547–549.PubMedGoogle Scholar
  61. 14.
    Allen ML (1947) X-ray therapy in the treatment of para-arthritis of the shoulder. Rocky Mountain Med J 44: 621–625.PubMedGoogle Scholar
  62. 15.
    Gelber U (1947) X-ray therapy of arthritis and bursitis. Medical Record 160: 344–350.PubMedGoogle Scholar
  63. 16.
    Pohle EA and Morton JA (1947) Roentgen therapy in arthritis, bursitis, and allied conditions. Radiology 49: 19–25.PubMedGoogle Scholar
  64. 17.
    Young BR (1947) The roentgen treatment of bursitis of the shoulder. Am J Roent Rad Ther Nucl Med 56: 626–630Google Scholar
  65. 18.
    Klein I (1946) Treatment of peritendinitis calcarea of the shoulder joint by roentgen irradiation. Am J Roent Rad Ther Nucl Med 56: 366–375.Google Scholar
  66. 19.
    Nobre MOR and de Araujo Cintra RR (1944) Radiotherapy in Duplay’s disease. Am J Roent Rad Ther Nucl Med 52: 415–422.Google Scholar
  67. 20.
    Baird LW (1941) Roentgen irradiation of calcareous deposits about the shoulder. Radiology 37: 316–324.Google Scholar
  68. 21.
    Klein I and Klemes IS (1941) Treatment of peritendinitis calcarea in the shoulder joint. Radiology 37: 325–330.Google Scholar
  69. 22.
    Pendergrass EP and Hodes PJ (1941) Roentgen irradiation in the treatment of inflammations. Am J Roent Rad Ther Nucl Med 45: 74–106.Google Scholar
  70. 23.
    Weinberg TB (1940) Arthritis and para-arthritis treated with the roentgen ray. Am J Roent Rad Ther Nucl Med 43: 416–424.Google Scholar
  71. 1.
    Anttinen J and Oka M (1975) Intra-articular triamcinolone hexacetonide and osmic acid in persistent synovitis of the knee. Scand J Rheum 4: 125–128.PubMedCrossRefGoogle Scholar
  72. 2.
    Bowen BM, Darracott J, Garnett ES and Tomlinson RH (1975) Yttrium 90 citrate colloid for radioisotope synovectomy. Am J Hosp Pharm 32: 1027–1030.PubMedGoogle Scholar
  73. 3.
    Gumpel JM, Beer TC, Crawley JCW and Farran HEA (1975) Yttrium 90 in persistent synovitis of the knee - a single centre comparison. The retention and extra-articular spread of four 90Y radiocolloids. Br J Rad 48: 377–381.CrossRefGoogle Scholar
  74. 4.
    Gumpel JM and Roles NC (1975) A controlled trial of intra-articular radiocolloids versus surgical synovectomy in persistent synovitis. Lancet 1: 488–489.PubMedCrossRefGoogle Scholar
  75. 5.
    Nissila A (1975) Osmic acid treatment for rheumatoid synovitis. Ann Clin Res 7: 202–204.Google Scholar
  76. 6.
    Oka M (1975) Radiation synovectomy of the rheumatoid knee with Yttrium 90. Ann Clin Res 7: 205–210.PubMedGoogle Scholar
  77. 7.
    Gumpel JM (1974) The role of radiocolloids in the treatment of arthritis. Rheum & Rehab 13: 1–9.CrossRefGoogle Scholar
  78. 8.
    Gumpel JM, Farran HEA and Williams ED (1974) Use of Yttrium 90 in persistent synovitis of the knee. II. Direct comparison of yttrium colloid resin and yttrium citrate. Ann Rheum Dis 33: 126–128.PubMedCrossRefGoogle Scholar
  79. 9.
    Pilgaard S, Kolind-Sorensen V and Munck J (1974) Synovectomy of the knee. Acta Orth Scand 45: 241–244CrossRefGoogle Scholar
  80. 10.
    Ansell BM (1973) Early studies of 198 Au in the treatment of synovitis of the knee. Ann Rheum Dis 32: Supple 1.Google Scholar
  81. 11.
    Bridgman JJ, Bruckner F, Eisen V, Tucker A and Bleehen NM (1973) Irradiation of the synovium in the treatment of rheumatoid arthritis. Qrtly J Med 42: 357–367.Google Scholar
  82. 12.
    Gumpel JM, Williams ED and Glass HI (1973) Use of yttrium 90 in persistent synovitis of the knee. I.Rentention in the knee and spread in body after injection. Ann Rheum Dis 32: 223–227.PubMedCrossRefGoogle Scholar
  83. 13.
    Ingrand J (1973) Characteristics of radioisotopes for intra-articular therapy. Ann Rheum Dis 32: Suppl 3–9.PubMedCrossRefGoogle Scholar
  84. 14.
    Jalava S (1973) Irradiation synovectomy: clinical study of 67 knee effusions intra-articularly irradiated with 90 Y resin. Curr Ther Res 15: 395–401.PubMedGoogle Scholar
  85. 15.
    Stevenson AC (1973) Chromosomal damage in human lymphocytes from radioisotope therapy. Ann Rheum Dis 32: Suppl 19–22.PubMedCrossRefGoogle Scholar
  86. 16.
    Stevenson AC, Bedford J, Dolphin GW, Purrott RF, Lloyd DC, Hill AGS, Hill HFH, Gumpel JM, Williams D, Scott JT, Tamsey NW, Bruckner FE and Fearn CBD (1973) Cytogenetic and scanning study of patients receiving intra-articular injections of gold 198 and yttrium 90. Ann Rheum Dis 32: 112–123.PubMedCrossRefGoogle Scholar
  87. 17.
    Winston MA, Bluestone R, Cracchiolo A and Bland WH (1973) Radioisotope synovectomy with P 32 chromic phosphate kinetic studies. J Nuc Med 14: 886–889.Google Scholar
  88. 18.
    Hazelman BL (1972) The painful stiff shoulder. Rheum Phys Med 11: 413–421.CrossRefGoogle Scholar
  89. 19.
    Ranawat CS, Ecker ML and Straub LR (1972) Synovectomy and debridement of the knee in rheumatoid arthritis (a study of 60 knees). Arth & Rheum 15: 571–581.CrossRefGoogle Scholar
  90. 20.
    Oka M, Rekonen A, Ruotsi A and Seppala O (1971) Intra-articular injection of Y-90 resin colloid in the treatment of rheumatoid knee joint effusions. Acta Rheum Scan 17: 148–160.Google Scholar
  91. 21.
    Goldie I, Rosengren B, Moberg E and Hedlin E (1970) Evaluation of radiation treatment of painful conditions of the locomotor system. A double blind study. Acta Rad (Ther) 9: 311–322.CrossRefGoogle Scholar
  92. 22.
    Graham R, Ramsey NW and Scott JT (1970) Radioactive colloidal gold in chronic knee effusions with Baker’s cyst formation. Ann Rheum Dis 29: 159–163.CrossRefGoogle Scholar
  93. 23.
    Prichard HL, Bridgman JF and Bleehen NM (1970) An investigation of radioactive yttrium (90Y) for the treatment of chronic knee effusions. Br J Rad 43: 466–470.CrossRefGoogle Scholar
  94. 24.
    Topp JR and Cross EG (1970) The treatment of persistent knee effusions with intra-articular radioactive gold: Preliminary report. Canad Med Ass J 102: 709–714.PubMedGoogle Scholar
  95. 25.
    Ahlberg A, Mikulowski P and Odelberg-Johnson 0 (1969) Intra-articular injection of radioactive gold in treatment of chronic synovial effusion in the knee. Acta Rheum Scand 15: 81–89.PubMedGoogle Scholar
  96. 26.
    Greens S, Clayton ML, Leidholt JD, Smyth CJ and Bartholomew BA (1969) Synovectomy and debridement of the knee in rheumatoid arthritis. J Bone & Joint Surg Am 51: 626–642.Google Scholar
  97. 27.
    Makin M and Robin GC (1968) Radioactive colloidal gold in the treatment of chronic synovial effusions. Proc Roy Soc Med 61: 908–910.PubMedGoogle Scholar
  98. 28.
    Fine PH, Faner PA, Albrecht M and Jacox RF (1967) Intra-articular radioactive gold (198Au) in the treatment of rheumatoid synovitis of the knee. Arth Rheum 10: 278Google Scholar
  99. 29.
    Johnson PM and Christian CC (1967) Colloidal chromic phosphate P32 for treatment of chronic synovial effusions. J Nuc Med 8: 274Google Scholar
  100. 30.
    Virkkunen M, Krusius FE and Heiskanen T (1967) Experiences of intra-articular administration of radioactive gold. Acta Rheum Scand 13: 81–91.PubMedGoogle Scholar
  101. 31.
    Lippincott SW (1966) Radiation therapy in the treatment of bursitis. Del Med J 10: 318–320.Google Scholar
  102. 32.
    Stevens J and Whitefield GA (1966) Synovectomy of the knee in rheumatoid arthritis. Ann Rheum Dis 25: 214–219.PubMedGoogle Scholar
  103. 33.
    Makin M and Robin GC (1964) Chronic synovial effusions treated with intra-articular radioactive gold. DAMA 188: 725–728.Google Scholar
  104. 34.
    Ansell BM, Crook A, Mallard JR and Bywaters EGL (1963) Evaluation of intra-articular colloidal gold Au 98 in the treatment of persistent knee effusions. Ann Rheum Dis 22: 435–439.PubMedCrossRefGoogle Scholar
  105. 35.
    Hurri L, Sievers K and Oka M (1963) Intra-articular osmic acid in rheumatoid arthritis. Acta Rheum Scand 9: 20–27.PubMedCrossRefGoogle Scholar
  106. 1.
    Valtonen EJ, Liling HG and Malmio K (1975) The value of roentgen irradiation in the treatment of painful degenerative and inflammatory musculoskeletal conditions. Scand J Rheumatol 4: 247–249.PubMedCrossRefGoogle Scholar
  107. 2.
    Plenk HP (1952) Calcifying tendinitis of the shoulder. Radiology 59: 384–389.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  1. 1.The Johns Hopkins HospitalBaltimoreUSA
  2. 2.School of MedicineStanford UniversityStanfordUSA

Personalised recommendations