Abstract
Benign neurofibroma most often occurs in association with von Recklinghausen disease, but may also occur independently. In von Recklinghausen disease sarcomatous changes occur without previous irradiation. Critical location and recurrence are the most common reasons for treatment of benign neurofibroma. Definitive radiation may be used in circumstances such that complete excision is not feasible, or where debulking plus radiation therapy may lead to control, or when excision to any extent is severely limited. High dose radiation therapy is then recommended. The limited literature for this condition is worthy of review prior to considering treatment. The usual proviso for risk-benefit and informed consent should be followed. Seventy-three percent of radiation oncologists in the national survey would not treat neurofibroma.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Tepper JE and Suit HD (1985) The role of radiation therapy in the treatment of sarcoma of soft tissue. Cancer Invest 3: 587–592.
Smalley SR, Rubin J and Leifermann KM (1984) Neurofibrosarcoma and the sign of Leser-Trelat. Ca 34: 295–298.
Greenberg HM, Goebel R, Weichselbaum RR, Greenberger JS, Chaffey JT and Cassady JR (1981) Radiation therapy in the treatment of aggressive fibromatosis. Int J Radiat Oncol Biol Phys 7: 305–310
Suit HD and Russell WO (1975) Radiation therapy of soft tissue sarcoma. Cancer 36: 759–764.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Order, S.E., Donaldson, S.S. (1990). Neurofibroma. In: Radiation Therapy of Benign Diseases. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97160-0_13
Download citation
DOI: https://doi.org/10.1007/978-3-642-97160-0_13
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-97162-4
Online ISBN: 978-3-642-97160-0
eBook Packages: Springer Book Archive