Advertisement

Lethal Midline Granuloma

Chapter
  • 85 Downloads
Part of the Medical Radiology book series (MEDRAD)

Abstract

Polymorphic reticulosis/lymphomatoid granulomatosis complex is the preferred term for lethal midline granuloma. Lethal midline granuloma includes a spectrum of etiologic possibilities, including bacterial, fungal, neoplastic, and unknown origins. When lethal midline granuloma is localized to the upper airways it is termed polymorphic reticulosis. It may produce erosion of the upper airway and face. When localized, it responds to radiotherapy. Differentiation from malignant lymphoma, bacterial infection, fungal infection and Wegener’s granulomatosis is essential for proper management.

Keywords

Hypertrophic Scar Triamcinolone Acetonide Lymphoid Hyperplasia Lymphomatoid Granulomatosis Lethal Midline Granuloma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Smalley SR, Cupps RE, Anderson JA, Ilstrup DM, McDonald TJ, Weiland LH and DeRemee RD (1988) Polymorphic reticulosis limited to the upper aerodigestive tract - natural history and radiotherapeutic considerations. Int J Radiat Oncol Bio! Phys 15 :599–605.CrossRefGoogle Scholar
  2. 2.
    Robinson ACR, Fraser I, Bailey D and O’Halloran MJ (1984) Idiopathic midline destructive disease - case report and review of the literature. Postgrad Med J 60 :471–473.PubMedCrossRefGoogle Scholar
  3. 3.
    Halperin EC, Dosoretz DE, Goodman M and Wang CC (1982) Radiotherapy of polymorphic reticulosis. Br J Radio! 55 : 645–649.CrossRefGoogle Scholar
  4. 4.
    DeRemar RA, Weiland LH and McDonald TJ (1980) Respiratory vasculitis. Mayo Clin Prac 55 :492–498.Google Scholar
  5. 5.
    Fauci AS, Johnson RE and Wolff SM (1976) Radiation therapy of midline granuloma. Ann Int Med 84 :140–147.PubMedGoogle Scholar
  6. 6.
    Schechter SL, Bole GG and Walker SE (1976) Midline granuloma and Wegener’s granulomatosis: clinical and therapeutic considerations. J Rhemato1 3: 241–250.Google Scholar
  7. 7.
    Harrison DFN (1974) Non-healing granulomata of the upper respiratory tract. Br Med J 4 : 205–209.PubMedCrossRefGoogle Scholar
  8. 8.
    Friedman I (1971) The changing pattern of granuloma of the upper respiratory tract. J Laryngol & Ostol 85 :631–682.Google Scholar
  9. 9.
    Jarrett JE and Lehman RH (1971) Lethal midline granuloma. A review of the literature. Rocky Mt Med J 68 :40–45.PubMedGoogle Scholar
  10. 10.
    Kassel SH, Echevarria RA and Guzzo FP (1969) Midline malignant reticulosis (so-called lethal midline granuloma). Cancer 23 :920–935.PubMedCrossRefGoogle Scholar
  11. 11.
    Eichel BS and Mabery TE (1968) The enigma of the lethal midline granuloma. Laryngoscope 78 :1367–1386.PubMedCrossRefGoogle Scholar
  12. 12.
    Friedman I (1964) Midline granuloma. Proc R Soc Med 57 :289–297.Google Scholar
  13. 13.
    Feder BGH, Shramek JH and Ikeda TS (1962) Large field radiotherapy in lethal midline granuloma. Radiology 81 :293–299.Google Scholar
  14. 14.
    Wildermuth O (1962) Lethal midline granuloma. Radiology 78 :269–271.PubMedGoogle Scholar
  15. 15.
    Merrill MD (1961) Roentgen therapy in Wegener’s granulomatosis. A case report. Am J Roentg Rad Ther & Nucl Med 85 :96–98.Google Scholar
  16. 16.
    Dickson RJ (1960) Radiotherapy of lethal midline granuloma. J Chronic Disease 12 :417–427.CrossRefGoogle Scholar
  17. 17.
    Blatt IM, Seltzer HS, Rubin P, Furstenberg AC, Maxwell JH and Schull WJ (1959) Fatal granulomatosis of the respiratory tract. Arch Otolaryngo1 70 : 707–757.CrossRefGoogle Scholar
  18. 18.
    Ellis M (1957) Malignant granuloma of the nose. Ann Otol Rhinol & Laryngol 66 :1002–1008.Google Scholar
  19. 19.
    Ellis M (1955) Malignant granuloma of the nose. Br Med J 1 : 1251–1253.PubMedCrossRefGoogle Scholar
  20. 20.
    Glass EJG (1955) Malignant granuloma. J Laryngol & Otol 69 :315–320.Google Scholar
  21. 1.
    Austin-Seymour MM, Donaldson SS, Egbert PR, McDougall IR and Kriss JP (1985) Radiotherapy of lymphoid diseases of the orbit. Int J Rad Oncol Biol Phys 11 :371–379.CrossRefGoogle Scholar
  22. 2.
    Meyers L and Hakami N (1985) Pseudotumor of hemophilia in the orbit. Am J of Hematology 19 :99–104.CrossRefGoogle Scholar
  23. 3.
    Olson LE, Wilson JF and Cox JD (1985) Cutaneous lym phoid hyperplasia: Results of radiation therapy. Radiology 155 :507–509.PubMedGoogle Scholar
  24. 4.
    Jereb B, Lee H, Jakobiec FA and Kutcher J (1984) Radiation therapy of conjunctival and orbital lymphoid tumors. Int J Radiation Oncol Biol Phys 10 :1013–1019.CrossRefGoogle Scholar
  25. 5.
    Sergott RC, Gaser JS and Charyulu K (1981) Radiotherapy for idiopathic inflammatory orbital pseudotumor: Indications and results. Arch Ophthalmol 99 :853–856.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  1. 1.The Johns Hopkins HospitalBaltimoreUSA
  2. 2.School of MedicineStanford UniversityStanfordUSA

Personalised recommendations