Synopsis
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1.
Eine Therapie mit Lithiumsalzen wurde bei verschiedenen neurologischen Erkrankungen erprobt.
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2.
Die prophylaktische Wirksamkeit von Lithium bei episodischem und chronischem Cluster-Kopfschmerz wurde in zahlreichen offenen Studien eindrucksvoll belegt. Doppelblinduntersuchungen stehen noch aus.
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3.
Bei der Migräne ist eine Behandlung mit Lithium möglicherweise erfolgversprechend, wenn die Erkrankung eine zyklische Verlaufsform („cyclical migraine“) aufweist.
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4.
Eine Wirksamkeit von Lithium bei anderen neurologischen Störungen (Morbus Menière, Epilepsie, Chorea Huntington, Morbus Parkinson, Spätdyskinesien, periodische Hypersomnie, Gilles-de-la-Tourette-Syndrom, Torticollis spasticus, hypokaliämisehe, periodische Lähmung) konnte bislang nicht nachgewiesen werden.
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5.
Bei symptomatischen affektiven Psychosen, die im Rahmen einer neurologischen Erkrankung auftreten, wurden Therapieerfolge mit Lithium beschrieben.
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Schölderle, M., Greil, W. (1986). Lithium in der Neurologie. In: Müller-Oerlinghausen, B., Greil, W. (eds) Die Lithiumtherapie Nutzen, Risiken, Alternativen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96935-5_21
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DOI: https://doi.org/10.1007/978-3-642-96935-5_21
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