Abstract
The gross appearance of a squamous cell carcinoma in the tongue of a rat is seen in Fig. 231 and may be compared with a normal rat tongue (Fig. 232). These tumors typically occur on the dorsal posterior aspect of the base of the tongue where the semilunar groove surrounds the vallate papilla. They appear as firm, usually white, papillary or fungiform masses. These masses can partially or totally occlude the lumen of the oral cavity and oropharynx and prevent ingestion of food. Smaller lesions may be present as papillary projections from the mucosal surface.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Greene EC (1963) Anatomy of the rat, Transactions of the American Philosophical Society, vol 27. Hafner, New York
Hebel R, Stromberg MW (1976) Anatomy of the laboratory rat. Williams and Wilkins, Baltimore
Hollander CF, van Rijssel TG (1963) Experimental production of intramandibular carcinoma in mice by mechanical damage. JNCI 30: 337–359
Keyes DG, Kociba RJ, Schwetz RW, Wade CE, Dittenber DA, Quinn T, Gorzinski SJ, Hermann EA, Momany JJ, Schwetz BA (1980) Results of a two-year toxicity and oncogenic study of rats ingesting diets containing dibromoneopentyl glycol (FR-1138). J Combustion Toxicol 7:76–98
Kociba RJ, Frauson LO, Humiston CG, Norris JM, Wade CE, Lisowe RW, Quast JF, Jersey GC, Jewett GL (1975) Results of a two year dietary feeding study with decabromodiphenyl oxide (DBDPO) in rats. J Combustion Toxicol 2: 267–285
Kociba RJ, Keyes DG, Jersey GC, Ballard JJ, Dittenber DA, Quast JF, Wade CE, Humiston CG, Schwetz BA (1977) Results of a two-year chronic toxicity study with hexachlorobutadiene in rats. Am Ind Hyg Assoc J 38: 589–602
Kociba RJ, Keyes DG, Beyer JE, Carreon RM, Wade CE, Dittenber DA, Kalnins RP, Frauson LE, Park CN, Barnard SD, Hummel RA, Humiston CG (1978) Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats. Toxicol Appl Pharmacol 46:279–303
Kociba RJ, Keyes DG, Lisowe RW, Kalnins RP, Dittenber DA, Wade CE, Gorzinski SJ, Mahle NH, Schwetz BA (1979) Results of a two-year chronic toxicity and oncogenic study of rats ingesting diets containing 2,4,5,-trichlorophenoxyacetic acid (2,4,5-T). Food Cosmet Toxicol 17: 205–221
van Rijssel TG, Mühlbock O (1955) Intramandibular tumors in mice. JNCI 16: 659–689
Weichert CK (ed) (1958) Organ systems in vertebrates. In: Anatomy of chordates. McGraw-Hill, New York
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kociba, R.J., Keyes, D.G. (1985). Squamous Cell Carcinoma, Tongue, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Digestive System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96910-2_44
Download citation
DOI: https://doi.org/10.1007/978-3-642-96910-2_44
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-96912-6
Online ISBN: 978-3-642-96910-2
eBook Packages: Springer Book Archive