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Experimental Carcinogenesis of Exocrine Pancreas: Animal Models, Neoplasms, and Current Understanding of Pathogenesis

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Digestive System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

The induction of neoplasms of the exocrine pancreas by chemical carcinogens has been achieved in several rodent species (Table 12). These have been the focus of research in a number of laboratories and have collectively contributed significantly to our understanding of pancreatic carcinogenesis. Although three rodent models have been identified, namely the rat, guinea pig, and Syrian golden hamster, the majority of research has been done with the rat and hamster. However, in an effort to be complete, all three models will be considered in this manuscript.

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Authors
  1. Dante G. Scarpelli
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  2. M. Sambasiva Rao
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  3. Janardan K. Reddy
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Editor information

Editors and Affiliations

  1. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA, 01772, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) & Ronald Duncan Hunt D.V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology, Emeritus) &  (Professor of Comparative Pathology)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, Federal Republic of Germany

    Ulrich Mohr M. D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1985 Springer-Verlag Berlin Heidelberg

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Scarpelli, D.G., Rao, M.S., Reddy, J.K. (1985). Experimental Carcinogenesis of Exocrine Pancreas: Animal Models, Neoplasms, and Current Understanding of Pathogenesis. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Digestive System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96910-2_40

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  • DOI: https://doi.org/10.1007/978-3-642-96910-2_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-96912-6

  • Online ISBN: 978-3-642-96910-2

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