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Strahlentherapie pp 1080-1332 | Cite as

Maligne Systemerkrankungen

  • K. Musshoff
  • H. Schmitz
  • H. Stein
  • U. Quast

Zusammenfassung

Unter dem Begriff der malignen Lymphome werden alle Neoplasien des lymphoretikulären Systems zusammengefaßt. Schon frühzeitig wurde durch die Arbeiten von Hodgkin (1832), Sternberg (1898) und Reed (1902) die maligne Lymphogranulomatose (Lgr) oder die Hodgkin-Erkrankung [Hodgkin’s disease (HD), Hodgkin-Lymphome (HL), Morbus Hodgkin (MH)] als eigene Krankheitsgruppe aus der vielgestaltigen Gesamtgruppe der malignen Lymphome abgegrenzt. Sie ist durch das Vorhandensein charakteristischer einkerniger Riesenzellen, der Hodgkin- (H-) und mehrkernigen Sternberg-Reed-(SR-)Zellen gekennzeichnet. In unserem Lande macht sie, bei unterschiedlicher Verteilung in anderen Ländern, etwa ein Drittel der malignen Lymphome aus.

Literatur

  1. Abbrederis K, Michlmayr G, Schmalz]. F, Huber H, Braunsteiner H (1973) Akute myelogene Leukämie des Erwachsenen. Dtsch Med Wschr 98: 1743CrossRefGoogle Scholar
  2. Abdou NL, Alavi JB, Abdou NI (1976) Human bone marrow lymphocytes B and T cells precursors and subpopulations. Blood 47: 423–429PubMedGoogle Scholar
  3. Adamson JW, Fialkow PJ, Murphy S, Prchal JF, Steinmann L (1976) Polycythemia vera: Stem-cell and probable clonal origin of the disease. N Engl J Med 295: 913–916Google Scholar
  4. Aget H (1982) Dosimetry of total body irradiation. J Eur Radiother 3: 183–190Google Scholar
  5. Airlie House Warrenton, Virginia (1975) Invitational workshop for the planning of retrospective and prospective studies to delineate optimal classifications of the non-Hodgkin’s lymphomas, September 4–5Google Scholar
  6. Aisenberg AC, Linggood RM, Lew RA (1979) The changing face of Hodgkin’s disease. Am J Med 67: 921–928PubMedCrossRefGoogle Scholar
  7. Aletti P (1982) Summary of the discussion on lung shielding. J Eur Radiother 3: 255–256Google Scholar
  8. Anderson V, Sorensen SF, Killmann SA (1968) Traitement de la leucémie lymphoide chronique par l’irradiation extracorporelle du sang. Nouv rev franç Hémet 8: 709Google Scholar
  9. Andersen V, Weeke E, Killmann SA (1974) Extracorporal irradiation of the blood: clinical applications. Strahlenther 148: 603–613Google Scholar
  10. Anderson JR, Wilson JF, Jenkin RDT, Meadows AT, Kersey J, Chilcote RR, Coccia P, Exelby Ph, Kushner J, Siegel S, Hammond D (1983) Childhood non-Hodgkin’s lymphoma. The results of a randomized therapeutic trial comparing a 4-drug regimen (COMP) with a 10-drug regimen (LSA2–L2). N Engl J Med 308, No. 10: 559PubMedCrossRefGoogle Scholar
  11. Anderson RE, Ishida K (1964) Malignant lymphoma in survivors of the atomic bomb in Hiroshima. Ann Intern Med 61: 853–862PubMedGoogle Scholar
  12. Anderson T, DeVita VT Jr, Simon RM, Beard CW, Canellos GP, Garvin AJ, Young RC (1982) Malignant lymphoma II. Prognostic factors and response to treatment of 473 patients at the National Cancer Institute. Cancer 50: 2708–2721PubMedCrossRefGoogle Scholar
  13. Andrews JR (1968) The radiobiology of human cancer radiotherapy. Saunders, PhiladelphiaGoogle Scholar
  14. Andrews JR (1978) The radiobiology of human radiotherapy. University Park Press, BaltimoreGoogle Scholar
  15. Annest LS, Anderson RP, Li W, Hafermann MD (1983) Coronary artery disease following mediastiel radiation therapy. I. Thorax Cardiovasc Surg 85: 257–263Google Scholar
  16. Applefeld MM, Wiernik PH (1983) Cardiac disease after radiation therapy for Hodgkin’s disease: analysis of 48 patients. Am J Cardiol 51: 1679–1681PubMedCrossRefGoogle Scholar
  17. Applefeld MM, Cole JF, Pollock SH, Sutton FT, Slawson RS, Singleton RT, Wiernik PH (1981 a) The late appearence of chronic pericardial disease in patients treated by radiotherapy for Hodgkin’s disease. Ann Intern Med 94: 338–341Google Scholar
  18. Applefeld MM, Slawson RG, Hall-Craigs M, Green DC, Singleton RT, Wiernik PH (1981 b) Delayed pericardial disease after radiotherapy. Am J Cardiol 47: 210–213Google Scholar
  19. Applefeld MM, Slawson RG, Spicer KM, Singleton RT, Wesley MN, Wiernik PH (1982) Longterm cardiovascular evaluation of patients with Hodgkin’s disease treated by thoracic mantle radiation therapy. Cancer Treatm Rep 66: 1003–1013Google Scholar
  20. Armitage JO, Burn CP (1977) Remission maintenance of adult acute lymphoblastic leukemia. Med Pediatr Oncol 3: 53PubMedCrossRefGoogle Scholar
  21. Aroesty JM, Furth FW (1962) Infection and chronic lymphocytic leukemia. A review of 61 cases. NY State J Med 62: 1946Google Scholar
  22. Audebert AA, Cussae A, Krulik M, Lecomte D, Lab JP, Berton JL, Graisely B, Debray J (1982) Etude des coronaropathies post-radiqués. Une observation. Ann Med Intern (Paris) 133: 269–271Google Scholar
  23. Aur RJA, Hustu HO, Verzosa MS, Wood A, Simone JV (1973) Comparison of two methods of preventing central nervous system leukemia. Blood 42: 1349Google Scholar
  24. Azar HA, Potter M (1973) Multiple myeloma and related disorders, vol I. Harper & Row, Hagerstown Md.Google Scholar
  25. Baccarani M, Corbelli G, Tura S and the Italian cooperative study group on chronic myeloid leukemia (1981) Early splenectomy and polychemotherapy versus polychemotherapy alone in chronic myeloid leukemia. Leukemia Res 5: 149–157CrossRefGoogle Scholar
  26. Bagley CM, DeVita VT Jr, Berard CW, Candlos GP (1972) Advanced lymphosarcoma: Intensive cyclical combination chemotherapy with cyclophosphamide, vincristine and prednisone. Ann Intern Med 76: 227–234Google Scholar
  27. Bagshaw MA, Eltringham JR (1968) Observations on the electron beam therapy of mycosis fungoides. Front Radiat Ther Onc 2: 163–182Google Scholar
  28. Baisogolow GD, Shishkin JP, Afanasova NV, Ozoline NG, Khmeivskaia ZI (1983) Early and late changes in the lungs following irradiation of the mediastinum (based on studies of patients with lymphogranulomatosis). Med Radiol (Mosk) 28: 22–31Google Scholar
  29. Bamberg M, Beelen DW, Mahmoud HK, Molls M, Schaefer UW (1986) The incidence of interstitial pneumonities: Comparison of total body irradiation schedules for allogenic bone marrow transplantation. Review. Strahlenther 162: 218–222Google Scholar
  30. Banfi A (1984) Persönliche MitteilungGoogle Scholar
  31. Banfi A, Bonadonna G, Carnevali G, Oldini C, Salvini E (1968) Preferential sites of involvement and spread in malignant lymphomas. Eur J Cancer 4: 319–324PubMedGoogle Scholar
  32. Banfi A, Bonadonna G, Ricci SB, Milani F, Molinari R, Monfardini S, Zucali R (1972) Malignant lymphomas of Waldeyer’s ring: natural history and survival after radiotherapy. Br Med J 111: 140–143CrossRefGoogle Scholar
  33. Barcos MP, Lukes RJ (1975) Malignant lymphoma of convoluted lymphocytes: A new entintity of possible T-cell type. In: Sinks LF, Godden JO (eds) Conflicts in childhood cancer. An evaluation of current management, vol IV. Liss, New York, pp 147–178Google Scholar
  34. Barrett A (1982 a) Total body irradiation before bone marrow transplantation. A review. Clin Radiol 33: 131–135Google Scholar
  35. Barrett A (1982 b) Clinical aspects of total body irradiation. J Eur Radiother 3:159–164Google Scholar
  36. Barrett A (1983) Systemic radiotherapy. In: Steel GG, Adams GE, Peckham MJ (eds) The biological basis of radiotherapy. Elsevier, Amsterdam New York Oxford, pp 249–259Google Scholar
  37. Barrett A, Depledge MH, Powles RL (1983) Interstitial pneumonitis following bone marrow transplantation after low dose rate total body irradiation. Int J Radiat Oncol Biol Phys 9: 1029–1033PubMedCrossRefGoogle Scholar
  38. Bartels H (1980) Prognose der malignen Lymphome der Keimzentren. Habilitationsschrift, Lübeck, zit. bei Lennert and SteinGoogle Scholar
  39. Bartels H (1983) Zur Prognose des primären Milzbefalls beim centroblastisch/centrozytischen malignen Lymphom. Onkologie 6: 229Google Scholar
  40. Bartels H, Burger A, Common H, Donhuijsen-Ant R, Graubner M, Grupp HJ, Huhn D, Leopold H, Nowicki L, Nürnberger R, Rühl U, Waldner R (Kieler Lymphomgruppe) (1979) Klinik and Prognose des centroblastisch-centrocytischen Lymphoms and des centroblastischen Lymphoms. In: Stacher A, Höcker P (Hrsg) Lymphknotentumoren, Pathophysiologie, Klinik and Therapie. Urban & Schwarzenberg, München, S 211–217Google Scholar
  41. Bartels H, Schneider B, Feller AC (1984) Klinik and Therapie des anaplastischen T-Zonen Lymphoms. Dtsch Med Wschr 109: 1112–1116PubMedCrossRefGoogle Scholar
  42. Bartels H, Stein H, Lennert K (1982) Clinical features and prognosis of morphologic subtypes of germinal center cell lymphoma. Verh Dtsch Krebs Ges 3: 585Google Scholar
  43. Bartl R, Frisch B, Burkhardt R, Hoffmann-Fezer G, Demmler K, Sund M (1982) Assessment of marrow trephine in relation to staging in chronic lymphocytic leukemia. Br J Haematol 51: 1–15PubMedCrossRefGoogle Scholar
  44. Bartl R, Frisch B, Hill W, Burkhardt R, Sommerfeld W, Sund M (1983) Bone marrow histology in hairy cell leukemia: identification on subtypes and their prognostic significance. Am J Clin Path 79: 531–545PubMedGoogle Scholar
  45. Bartl R, Frisch B, Burkhardt R, Jäger K, Pappenberger R, Hoffmann-Fezer G (1984) Lymphoproliferations in the bone marrow: identification and evolution, classification and staging. J Clin Path 37: 233–254PubMedCrossRefGoogle Scholar
  46. Bataille R (1982) Localized plasmocytomas. Clin Haemat 11: 113–122PubMedGoogle Scholar
  47. Beard MEJ, Fairley GH (1974) Acute leukemia in adults. Sem Hemat 11: 5Google Scholar
  48. Bearman RM, Pangalis GA, Rappaport H (1979) Acute (malignant) myelosclerosis. Cancer 43: 279–293PubMedCrossRefGoogle Scholar
  49. Becker N, Frentzel-Beyme R, Wagner G (1984) Krebsatlas der Bundesrepublik Deutschland, 2. Aufl. Springer, Berlin Heidelberg New YorkGoogle Scholar
  50. Benjamin D, Magrath IT, Douglas EC, Corash LM (1983) Derivation of lymphoma cell lines from microscopically normal bone marrow in patients with undifferentiated lymphomas. Evidence of occult bone marrow involvement. Blood 61: 1017–1019Google Scholar
  51. Bennett JM (1983) Controversies in the management of lymphomas. Nijhoff, Boston The Hague Dordrecht Lancaster, pp 1–302CrossRefGoogle Scholar
  52. Bennett MH, Millet YL (1969) Nodular sclerotic lymphosarcoma. A possible new clinico-pathological entity. Clin Radiol 20: 339–343Google Scholar
  53. Bennett MH, Tu A, Vaughan Hudson B (1981) Analysis of grade I Hodgkin’s disease (BNLI report No. 6). Clin Radiol 32: 491–498PubMedCrossRefGoogle Scholar
  54. Bennett MH, Farrer-Brown G, Henry K, Jelliffe AM (1974) Classification of non-Hodgkin’s lymphomas. Lancet II: 405–406Google Scholar
  55. Bennett MH, Mac Lennan KA, Easterling MJ, Vaughan Hudson B, Vaughan Hudson G, Jeliffe AM (1983) The prognostic significance of cellular subtypes in nodular sclersing Hodgkin’s disease: an analysis of 271 non laparotomised cases. Clin Radiol 34: 497–501PubMedCrossRefGoogle Scholar
  56. Bennett MH, Mac Lennan KA, Easterling MJ, Vaughan Hudson B, Vaughan Hudson G, Jelliffe AM (1985) Analysis of histological subtypes in Hodgkin’s disease in relation to prognosis and survival. In: Quaglino D, Hayhos FGI (eds) The cytobiology of leukaemias and lymphomas. Raven Press, New York, pp 15–32Google Scholar
  57. Berard CW, Cossman J, Jaffe ES (1980) Malignant lymphomas as tumours of the immune system. Br J Cancer 42: 1–20PubMedCrossRefGoogle Scholar
  58. Berard CW, Thomas LB, Axtell LM, Kruse M, Newell G, Kagan R (1971) The relationship of histopathological subtype to clinical stage of Hodgkin’s disease at diagnosis. Cancer Res 31: 1776–1785Google Scholar
  59. Bergsagel DE (1971) Total body irradiation in myelomatosis. Br Med J 11: 325CrossRefGoogle Scholar
  60. Berk PD, Goldberg JD, Silverstein MN, Weinfeld A, Donovan PB, Ellis JT, Landaw SA, Laszlo J, Najean Y, Pisciotta AV, Wasserman LR (1981) Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy. N Engl J Med 304: 441–447PubMedCrossRefGoogle Scholar
  61. Bernasconi C, Castelli G, Brusamolino E, Pagnucco G, Isernia P (1981) Clinico-pathological study on 215 cases of non-Hodgkin lymphomas (NHLs), defined according to the Kiel classification. Int Conf on Malignant Lymphoma, Lugano, Abstract T 3Google Scholar
  62. Berndt H, Hendel V (1984) Zur Inzidenz an malignen Lymphomen mit Leukämien in der DDR. Z Ges Inn Med 39: 73–76PubMedGoogle Scholar
  63. Beyer D, Peters PE (1980) Real time ultrasonography. An effective screening method for abdominal and pelvic lymphadenopathy. Lymphology 13: 142Google Scholar
  64. Beyer D, Lorenz R, Mödder N, Steinbrich W (1985) Diagnostik des extranodalen Befalls bei Non-Hodgkin-Lymphom im Abdominal-und Retroperitonealraum mit Sonographie und Computertomographie. Radiol 25: 206–212Google Scholar
  65. Biermann JM, Siegel E, French FE, Simonian K (1965) Analysis of the outcome of cell pregnancies in a community: Kanai pregnancy study. Am J Obst Gynec 91: 37–45Google Scholar
  66. Billroth T (1871) Multiple Lymphome. Erfolgreiche Behandlung mit Arsenik. Wien Med Wschr 21: 1065Google Scholar
  67. Binet JL, Leporrier M, Dighiero G, Charron D, D’Athis PH, Vaugier G, Merle Beral H, Natali JC, Raphael M, Nizet B, Follezou JY (1977) A clinical staging system for chronic lymphocytic leukemia. Cancer 40: 855–864PubMedCrossRefGoogle Scholar
  68. Binet JL, Auquier A, Dighiero G, Chastang C, Piquet H, Goasguen J, Vauguier G, Potron G, Colona P, Oberling F, Thomas M, Tchernia G, Jacquillat D, Boivin P, Lesty C, Duault MT, Mont Conduit M, Belabbes S, Gremy F (1981 a) A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 48: 198–206Google Scholar
  69. Binet JL, Catovsky D, Chandra P, Dighiero G, Montserrat E, Rai KR, Sawitsky A ( 1981 b) Chronic lymphocytic leukaemia: Proposals for a revised prognostic staging system. Report from the International Workshop on CLL. Br J Haemat 48: 365–367Google Scholar
  70. Bishop JM (1985) Viral oncogenes. Cell 42: 23–38PubMedCrossRefGoogle Scholar
  71. Bishop YMM, Sienberg SE, Holland PW (1975) Discrete Multi Variate Analysis: Theory and practice. MIT Press, Cambridge MAGoogle Scholar
  72. Bitran JD, Kinzie J, Sweet DL, Variokojis D, Griem ML, Golomb HM, Miller JB, Noetzel N, Ultmann JE (1977) Survival of patients with localized histiocytic lymphoma. Cancer 39: 342–346PubMedCrossRefGoogle Scholar
  73. Blick M, Barlogie B, Hagemeister F, Cabanillas F, Osborne B, Butler J, Lewin T, Eckles NE (1983) Cytometry of malignant lymphoma: comparison with histopathology and prognostic implications AACR Abstr No. 500: 127Google Scholar
  74. Bloomfield CD, McKenna RW, Brunning RD (1976) Significance of haematological parameters in the non-Hodgkin’s malignant lymphomas. Br J Haemat 32: 41–46CrossRefGoogle Scholar
  75. Bodensteiner DC, Skikne B (1982) Central nervous system involvement in mycosis fungoides. Diagnosis, treatment and literature review. Cancer (Philad) 50: 1181–1184Google Scholar
  76. Bofill M, Janossy G, Janossa M, Burford GD et al. (1985) Human B cell development. II. Sub-populations in the human fetus. J Immunol 134: 1531–1538Google Scholar
  77. Boggs DR, Sofferman SA, Wintrobe MM, Cartwrigth GE (1966) Factors influencing the duration of survival of patients with chronic lymphocytic leukemia. Am J Med 40: 243–254PubMedCrossRefGoogle Scholar
  78. Boivin JF, Hutchison GB (1982) Coronary heart disease mortality after irradiation for Hodgkin’s disease. Cancer 49: 2470–2475PubMedCrossRefGoogle Scholar
  79. Bonadonna G, Lattuada A, Monfardini S, Bajetta E, Buzzoni R, Canetta R, Valagussa P, Banfi A (1982) The role of combined radiotherapy and chemotherapy in the primary management of non-Hodgkin’s lymphomas. In: Rosenberg SA, Kaplan HS (eds) Malignant lymphomas, etiology-immunology, pathology, treatment. Academic Press, New York London, pp 537–551Google Scholar
  80. Bonadonna G, Santoro A (1982) Evolution in the treatment strategy of Hodgkin’s disease. Advances Cancer Research 36. Academic Press Inc, New YorkGoogle Scholar
  81. Bonadonna G, Zucali R, Monfardini S, De Lena M, Uslenghi C (1975) Combination chemotherapy of Hodgkin’s Disease with Adriamycin, Bleomycin, Vinblastine and Imidazole Carboxamide versus MOPP. Cancer 36: 252–259Google Scholar
  82. Bonadonna G, Viviani S, Bonfante V, Valagussa P, Santoro A (1984) Alternating chemotherapy with MOPP/ABVD in Hodgkin’s disease: updated results. ASCO Abstr C 994Google Scholar
  83. Bousser J, Bilski-Pasquier G, Blane C (1967) Vergleichende Untersuchungen zur Behandlung der chronischen myeloischen Leukämie mit Röntgenstrahlen and Myleran. Deutscher Röntgenkongreß 1966 Sonderband zur Strahlentherapie, Teil B: 271–275Google Scholar
  84. Branehög I, Ridell B, Swolin B, Weinfeld A (1975) Megakryocyte quantifications in relation to thrombokinetics in primary thrombocythaemia and allied diseases. Scand J Haemat 15: 231–332Google Scholar
  85. Braun-Falco O, Kresbach H, Burg G, Kerl H (1982) German-Austrian cutaneous lymphoma cooperative study group. In: Goos M, Christophers E (eds) Lymphoproliferative diseases of the skin. Springer, Berlin Heidelberg New York, pp 256–259CrossRefGoogle Scholar
  86. Bremer K, Brittinger G (1980) Maligne Lymphome I Histologische Klassifikation, Stadieneinteilung and Prinzipien der Therapie bei Morbus Hodgkin and non-Hodgkin Lymphomen. Intern Welt 3: 180–186Google Scholar
  87. Bremer K, Bartels H, Brittinger G, Burger A, Dühmke E, Gunzer U, König E, Stacher A, Theml H, Waldner R ( Kiel Lymphoma Group ) (1977) ClinicalGoogle Scholar
  88. of non-Hodgkin’s lymphomas (NHL). In: Seno S, Takaku F, Inno S (eds) Topics in haematology. Int Congr Ser Excerpta Media. Amsterdam, pp 352–355Google Scholar
  89. Brescia MJ, Cimino JE, Appel K, Huntrich BJ (1966) New Engl J Med 275: 20–89CrossRefGoogle Scholar
  90. Brill NE, Baehr G, Rosenthal N (1925) Generalized giant lymph follicle hyperplasia of lymph-nodes and spleen. A hitherto undescribed type. J Am Med Assoc 84: 668Google Scholar
  91. Brittinger G, Bartels H, Bremer K, Dühmke E, Gunzer U, König E, Stein H (Kieler Lymphomgruppe) (1976) Klinik der malignen Non-Hodgkin-Lymphome entsprechend der Kiel-Klassifikation: Centrocytisches Lymphom, centroblastisch-centrocytisches Lymphom, lymphoblastisches Lymphom, immuno-blastisches Lymphom. In: Löffler H (Hrsg) Maligne Lymphome und monoklonale Gammapathien, Bd XVIII: Hämatologie und Bluttransfusion. Lehmann, München, S 211–223Google Scholar
  92. Brittinger G, Bartels H, Bremer K, Burger A, Dühmke E, Gunzer U, König E, Stacher A, Stein H, Theml H, Waldner R (Kieler Lymphomgruppe) (1977) Retrospektive Untersuchungen zur klinischen Bedeutung der Kiel-Klassifikation der malignen Non-Hodgkin-Lymphome. Strahlenther 153: 222–228Google Scholar
  93. Brittinger G, Bartels H, Burger A, Dühmke E, Fülle HH, Gunzer U, Heinz R, Huhn D, Löhr GW, Musshoff K, Nowicki L, Pfoch M, Pralle H, Schmalhorst U (Kieler Lymphomgruppe) (1979) Grundlagen und bisherige Ergebnisse der prospektiven Studie der Kieler Lymphomgruppe über Non-Hodgkin-Lymphome. In: Stacher A, Höcker P (Hrsg) Lymphknotentumoren, Pathophysiologie, Klinik und Therapie. Urban & Schwarzenberg, München, S 193–200Google Scholar
  94. Brittinger G, Bartels H, Common H, Dühmke E, Engelhard M, Fülle HH, Gunzer U, Gyenes T, Heinz R, König E, Meusers P, Pralle H, Theml H, Zwingers T, Musshoff K, Stacher A, Brücher H, Herrmann F, Ludwig WD, Pribilla W, Burger-Schüler A, Löhr GW, Gremmel H, Oertel J, Gerhartz H, Koeppen KM, Boll I, Huhn D, Binder T, Schoengen A, Nowicki L, Pees HW, Scheurlen PG, Leopold H, Wannenmacher M, Schmidt M, Löffler H, Michlmayr G, Thiel E, Zettel R, Rühl U, Wilke HJ, Schwarze EW, Stein H, Feller AC, Lennert K (Kieler Lymphomgruppe) (1968) Klinische und prognostische Relevanz der Kiel-Klassifikation der Non-Hodgkin-Lymphome. Oncology 9: 118–125Google Scholar
  95. Brittinger G, Schmalhorst U, Bartels H, Fülle HH, Gerhartz H, Gremmel G, Grisar T, Grupp HJ, Gunzer U, Huhn D, Koeppen KM, Kubanek B, Leopold H, Löffler H, Löhr GW, Nowicki L, Rühl U, Schmidt M, Stacher A, Theml H, Lennert K (Kiel Lymphoma Study Group) (1981) Principles and present status of a prospective multicenter study on the clinical relevance of the Kiel classification. Blut 43: 155–166CrossRefGoogle Scholar
  96. Brittinger G, Bartels H, Common H, Dühmke E, Fülle HH, Gunzer U, Gyenes T, Heinz R, König E, Meusers P, Paukstat M, Pralle H, Theml H, Lennert K, Schwarze EW, Köpcke W, Zwingers T, Musshoff K, Stacher A, Brücher H, Pribilla W, Löhr GW, Oertel J, Boll I, Huhn D, Binder T, Nowicki L, Scheurlen PG, Leopold H, Schmidt M, Löffler H, Michlmayr G, Thiel E (Kieler Lymphomgruppe) (1983) Klinik, Prognose und internistische Therapie der Non-Hodgkin-Lymphome von hohem Malignitätsgrad. Verh Dtsch Ges Inn Med 89: 337–352Google Scholar
  97. Brittinger G, Bartels H, Common H, Dühmke E, Fülle HH, Gunzer U, Gyenes T, Heinz R, König E, Meusers P, Paukstat P, Pralle H, Theml H, Köpcke W, Thieme C, Zwingers T, Musshoff K, Stacher A, Brücher H, Herrmann F, Ludwig WD, Pribilla W, Burger-Schüller A, Löhr GW, Gremmel H, Oertel H, Gerhartz H, Koeppen KM, Boll I, Huhn D, Binder T, Schoengen A, Nowicki L, Pees HW, Scheurlen PG, Leopold H, Wannenmacher M, Schmidt M, Löffler H, Michlmayr G, Thiel E, Zettel R, Rühl U, Wilke HJ, Schwarze EW, Stein H, Feller AC, Lennert K (1984) Clinical and prognostic relevance of the Kiel classification of non-Hodgkin lymphomas. Results of a prospective multicenter study by the Kiel lymphoma study group. Hematol Oncol 2: 269–306Google Scholar
  98. Brittinger G, Meusers P, Musshoff K in Zusammenarbeit mit Gyenes T (1985) Non-HodgkinLymphome und Plasmozytom. In: Gross R, Schmidt CG (Hrsg) Klinische Onkologie. Thieme, Stuttgart New York, pp 41. 1–81Google Scholar
  99. Brix R, Dühmke E, Gremmel H, Hebbinghaus D, Jensen M (1984) Optimierung der Dosisverteilung bei der Ganzkörperbestrahlung durch Kompensatoren. Strahlenther 160: 108–113Google Scholar
  100. Brodsky I, Fuscaldo KE, Kahn SB, Conroy JF (1979) Myeloproliferative disorders: II CML: Clonal evolution and its role in management. Leukemia Res 3: 379–393Google Scholar
  101. Broerse JJ, Dutreix A (eds) (1982) Meeting of Leiden: Physical aspects of total body irradiation. J Eur Radiother 3: 157–264Google Scholar
  102. Brogadir S, Fialk M, Coleman M et al. (1978) Morbidity of staging laparotomy in Hodgkin’s disease. Am J Med 64: 429–433PubMedCrossRefGoogle Scholar
  103. Brunning RD, Bloomfield CD, McKenna RW, Peterson L (1975) Bilateral trephine bone mar- row biopsies in lymphoma and other neoplastic diseases. Ann Intern Med 82: 365–366PubMedGoogle Scholar
  104. Brusamolino E, Magrini U, Canevari A, Castelli G, Morra E, Pagnucco G, Isernia P, Bernasconi C (1983) Low-grade malignancy non-Hodgkin’s lymphomas: prognostic relevance of their clinicopathologic heterogeneity. Tumori 69: 331–338PubMedGoogle Scholar
  105. Büchner SA, Obrecht JP ( 1982 a) Mycosis fungoides. In: Schwiegk H (ed) Handbuch der inneren Medizin, Bd II/7. Springer, Berlin Heidelberg New York, pp 502–517Google Scholar
  106. Büchner SA, Obrecht JP ( 1982 b) Sezary-Syndrom. In: Schwiegk H (ed) Handbuch der inneren Medizin, Bd 1I/7. Springer, Berlin Heidelberg New York, S 517–530Google Scholar
  107. Bunn PA Jr, Fishman AB, Glatstein E (1982) Staging and treatment of the cutaneous T cell lymphomas (mycosis fungoides and the Sezary syndrome) at the National Cancer Institute (USA). In: Goos M, Christophers E (eds) Lymphoproliferative diseases of the skin. Springer, Berlin Heidelberg New York, pp 270–282Google Scholar
  108. Bunn PA Jr, Lamberg SI (1979) Report of the committee on staging and classification of cutaneous T-cell lymphomas. Cancer Treatm Rep 63: 725–728Google Scholar
  109. Bunn PA Jr, Hubermann MS, Whang-Peng J, Schechter GP, Guccion JG, Matthews MJ, Gaz-dar AF, Dunnick NR, Fischmann AB, Ihde DC, Cohen MH, Fossieck B, Minna JD (1980) Prospective staging evaluation of patients with cutaneous T-cell lymphomas. Demonstration of a high frequency of extracutaneous dissemination. Ann Intern Med 93: 223–230Google Scholar
  110. Burkhardt R (1970) Farbatlas der klinischen Histopathologie von Knochenmark and Knochen. Springer, Berlin Heidelberg New York, S 67–76Google Scholar
  111. Burkhardt R, Kronseder A (1977) Megakaryozytäre Myelose. — Ursache der „idiopathischen“ Thrombozythämie. Fortschr Med 95: 1261–1266PubMedGoogle Scholar
  112. Burns RJ, Bar-Shlomo BZ, Druck MN, Herman JG, Gilbert BW, Perrault DJ, McLaughlin PR (1983) Detection of radiation cardiomyopathy by gated radionuclide angiography. Am J Med 74: 297–302PubMedCrossRefGoogle Scholar
  113. Burrichter H, Heit W, Schaadt M et al. (1983) Production of colony stimulating factors by Hodgkin cell lines. In: Int J Cancer 31: 269–274Google Scholar
  114. Butcher EC, Jalkanen S, Herron L, Bargatze R (1984) Approaches to understanding the role of normal lymphocyte homing mechanisms in the spread of human lymphoid neoplasms. In: Ford RJ, Fuller LM, Hagemeister FB (eds) UT MD Anderson Clinical Conference on Cancer 27. Raven Press, New York, pp 191–199Google Scholar
  115. Butler JJ (1971) Relationship of histological findings to survival in Hodgkin’s disease. Cancer Res 31: 1770–1775PubMedGoogle Scholar
  116. Butler JJ (1983) The Lukes-Butler classification of Hodgkin’s disease revisited. In: Bennett JM (ed) Controversies in the management of lymphomas. Nijhoff, Boston, pp 1–18CrossRefGoogle Scholar
  117. Byhardt RW, Brace K, Wiernik PM (1975) Role of splenic irradiation in chronic lymphocytic leukemia. Cancer 35: 1622–1625Google Scholar
  118. Cabanillas F (1985) Chemotherapy as definitive treatment of stage I—II large cell and diffuse mixed lymphomas. Hematol Oncol 3: 25–31PubMedCrossRefGoogle Scholar
  119. Cabanillas F, Burgess MA, Bodey GP, Freireich EJ (1983) Sequential chemotherapy and late intensification for malignant lymphomas of aggressive histologic type. Am J Med 74: 382–388PubMedCrossRefGoogle Scholar
  120. Cabanillas F, Hagemeister FB, Bodey GP, Freireich EJ (1982) An effective regimen for patients with lymphoma who have relapsed after initial combination chemotherapy. Blood 60: 693–697PubMedGoogle Scholar
  121. Cadman EC, Copicci RL, Bertino JR (1977) Acute non-lymphatic leukemia: A delayed complication of Hodgkin’s disease therapy: analysis of 109 cases. Cancer 40: 1280–1296PubMedCrossRefGoogle Scholar
  122. Callender GR (1934) Tumors and tumor-like conditions of the lymphocyte, the myelocyte, the erythrocyte and reticulum cell. Am J Path 10: 443PubMedGoogle Scholar
  123. Canellos GP, Young RC, DeVita VT (1972) Combination chemotherapy for advanced Hodg- kin’s disease in relaps following extensive radiotherapy. Clin Pharmacol Ther 13: 750–754Google Scholar
  124. Carbone A, Santoro A, Pilotti S, Rilke F (1978) Bone marrow patterns and clinical staging in chronic lymphocytic leukemia. Lancet 1: 606PubMedCrossRefGoogle Scholar
  125. Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M (1971) Report of the committee on Hodgkin’s disease staging classification. Conference on staging in Hodgkin’s disease. Ann Arbor, April 26–28, Cancer Res 31: 1860–1861PubMedGoogle Scholar
  126. Carmel RJ, Kaplan HS (1976) Mantle irradiation in Hodgkin’s disease. An analysis of technique, tumor eradication and complications. Cancer 37: 2813–2825Google Scholar
  127. Castellino RA (1982) Imaging techniques for staging abdominal Hodgkin’s disease. Cancer Treatm Rep 66: 697–700Google Scholar
  128. Castellino RA, Marglin SI (1979) Lymphographic accuracy in consecutive previously untreated patients with Hodgkin’s disease and non-Hodgkin’s lymphoma. 7th Int Congress of Lymphology, Florence, ProceedingGoogle Scholar
  129. Castellino RA, Marglin SI (1982) Progress in clinical radiology. Imaging of abdominal and pelvic lymph nodes lymphography or computed tomography. Invest Radiol 17: 433–443Google Scholar
  130. Castellino RA, Dunnick NR, Goffinet DR, Rosenberg SR, Kaplan HS (1983) Predictive value of lymphography for sites of subdiaphragmatic disease encountered at staging laparotomy in newly diagnosted Hodgkin’s disease and non-Hodgkin’s lymphoma. J Clin Oncol 1: 532–536PubMedGoogle Scholar
  131. Catovsky D (1977) Hairy-cell leukaemia and prolymphocytic leukaemia. Clin Haemat 6: 245–268PubMedGoogle Scholar
  132. Catovsky D, Lauria F, Matutes E, Foa R, Mantovani V, Tura S, Galton DAG (1981) Increase in Ty lymphocyte in B cell chronic lymphocytic leukemia. II. Correlation with clinical stage and findings in B-prolymphocytic leukemia. Br J Haematol 47: 539–544Google Scholar
  133. Chabner BA, Johnson RE, DeVita VT, Canellos GP, Hubbard SP, Johnson SK, Young RC (1977) Sequential staging in non-Hodgkin’s lymphoma. Cancer Treatm Rep 61: 993–997Google Scholar
  134. Charron D, Dighiero G, Raphael M, Binet JL (1977) Bone marrow patterns and clinical staging in chronic lymphocytic leukemia. Lancet 11: 819CrossRefGoogle Scholar
  135. Cheever MA, Feter A, Greenberg PD, Appelbaum F, Armitage JO, Buckner CD, Sale GE, Storb R, Witherspoon RP, Thomas ED (1982) Treatment of hairy-cell leukemia with chemoradiotherapy and identical-twin bone-marrow transplantation. N Engl J Med 307: 479–481PubMedCrossRefGoogle Scholar
  136. Chen MG, Prosnitz LR, Gonzales-Serva A, Fischer DB (1979) Results of radiotherapy in control of stage I and II non-Hodgkin’s lymphoma. Cancer 43: 1245–1254PubMedCrossRefGoogle Scholar
  137. Chorazzi N, Fu SM, Ghodiat M, Kunkel HG, Rai K, Gee T (1979) T-cell helper defect in patients with chronic lymphocytic leukemia. J Immunol 122: 1087–1090Google Scholar
  138. Christensson B (1983) Studies on non-Hodgkin’s lymphomas: Immunological and flow-cyto- fluorometric DNA-analysis in relation to morphology and prognosis. Thesis, StockholmGoogle Scholar
  139. Chu A, Berger CL, Lynfield Y, Esseesse I, Edelson RL (1982) Pathogenesis of cutaneous T cell lymphoma. In: Christophers GME (ed) Lymphoproliferative diseases of the skin. Springer, Berlin Heidelberg New York, pp 57–64CrossRefGoogle Scholar
  140. Cionini L, Bastiani P, Biti GP, Mungai V, Ponticelli P, Lollo SD (1985) Waldeyer’s ring involvement in Hodgkin disease. Radiother Oncol 3: 299–302PubMedCrossRefGoogle Scholar
  141. Clarkson B, Ellis S, Little C, Gee T, Arlin Z, Mertelsmann R, Andreeff M, Kempin S, Koziner B, Chaganti R, Jhanwar S, McKenzie S, Cirrincione C, Gaynor J (1985) Acute lymphoblastic leukemia in adults. Seminars in Oncology 12: 160–179PubMedGoogle Scholar
  142. Clarkson BD, Dowling MD, Gee TS, Cunningham IB, Burchenal JH (1976) Treatment of acute leukemia in adults. Cancer 36: 775CrossRefGoogle Scholar
  143. Cleary ML, Sklar J (1984) Lymphoproliferative disorders in cardiac transplant recipients are multiclonal lymphoma. Lancet 11: 489–493CrossRefGoogle Scholar
  144. Clemmesen J (1965) Statistical studies in malignant neoplasmas I. Review and results. Munksgaard, Copenhagen, pp 453–455Google Scholar
  145. Cloutier RJ, O’Faghludha E, Comas FV (eds) (1967) Meeting of Oak Ridge 1967. Conference on dosimetry of total body irradiation by external photon beams. Oak Ridge Associated Universities, Conf — 670219, Health and Safety (TLD-4500)Google Scholar
  146. Colby TV (1983) Pitfalls in the diagnosis and classification of Hodgkin’s disease: surgical pathology and classification for the 1980’s — is the Lukes-Butler classification still relevant? In: Bennett JH (eds) Controversies in the management of lymphomas. Nijhoff, Boston, pp 19–53CrossRefGoogle Scholar
  147. Cole P, Mac Mahon B, Aisenberg A (1968) Mortality from Hodgkin’s disease in the United States. Evidence for the multiple-aetiology hypothesis. Lancet 11: 1371–1376Google Scholar
  148. Coleman CN, Burke JS, Varghese A, Rosenberg SA, Kaplan HS (1982) Secondary leukemia and non-Hodgkin’s lymphoma in patients treated for Hodgkin’s disease. In: Rosenberg SA, Kaplan HS (eds) Malignant lymphomas: etiology, immunology, pathology, treatment. Academic Press, New York, pp 259–267Google Scholar
  149. Coleman CN, McDougall IR, Dailey MO, Ager P, Bush S, Kaplan HS (1982) Functional hyposplenia after splenic irradiation for Hodgkin’s disease. Ann Intern Med 96: 44–47PubMedGoogle Scholar
  150. Coller BS, Chabner BA, Gralnick HR (1977) Frequencies and patterns of bone marrow involvement in non-Hodgkin’s lymphomas. Observations on the value of bilateral biopsies. Am J Hemat 3: 105–119PubMedGoogle Scholar
  151. Coltman CA Jr, Dixon DO (1982) Second malignancies complicating Hodgkin’s disease: a southwest oncology group 10-year follow-up. Cancer Treatm Rep 66: 1023–1033Google Scholar
  152. Conrad FG (1973) Survival in chronic granulocytic leukemia. Arch Intern Med 131: 684–685PubMedCrossRefGoogle Scholar
  153. Cosset JM, Henry-Amar M, Carde D, Clarke D, Le Bourgeois JP, Tubiana M (1984) The prognostic significance of large mediastinal masses in the treatment of Hodgkin’s disease. The experience of the Institut Gustave-Roussy. Hematol Oncol 2: 33–43Google Scholar
  154. Costa A, Bonadonna G, Villa E, Valagussa P, Silvestrini R (1981) Labelling index as a prognostic marker in non-Hodgkin’s lymphoma. J Natl. Cancer Inst 60: 1–5Google Scholar
  155. Cox DR (1970) Analysis of binary data. Methuen, LondonGoogle Scholar
  156. Cox DR (1972) Regression model and life tables. J R Stat Soc 34: 187–220Google Scholar
  157. Cox JD (1978) Central lymphatic irradiation to low dose advanced nodular lymphoreticular tumors (non-Hodgkin’s lymphoma). Radiol 126: 767–772Google Scholar
  158. Cox JD (1985) Persönliche MitteilungGoogle Scholar
  159. Cox JD, Koehl RH, Turner WM, King FM (1974) Irradiation in the local control of malignant lymphoreticular tumors (non-Hodgkin’s malignant lymphoma). Radiol 112: 179–185Google Scholar
  160. Cronkite EP, Chanana AD, Schnappauf H (1965) Extracorporal irradiation of blood and lymph in animals: its effect on homografts and lymphoma. N Engl J Med 272: 456–461PubMedCrossRefGoogle Scholar
  161. Cronkite EP, Jansen CR, Cottier H, Rai K, Sipe CR (1964) Lymphocytic production measured by extracorporal irradiation, cannulation and labeling techniques. Ann NY Acad Sci 113: 566–577PubMedCrossRefGoogle Scholar
  162. Crowther D (1981) New approaches in the management of patients with non-Hodgkin-Lymphoma of high-grade pathology. Br J Cancer 43: 417–435PubMedCrossRefGoogle Scholar
  163. Cunningham I, Gee T, Dowling M, Chaganti R, Bailey R, Hopfan S, Bowden L, Turnbull A, Knapper W, Clarkson B (1979) Results of treatment of Phl + chronic myelogenous leukemia with an intensive treatment regimen (L-5 protocol). Blood 53: 375–395PubMedGoogle Scholar
  164. Cunningham JR (1962) Tissue inhomogeneity corrections in photon-beam treatment planning. In: Orton CG (ed) Progress in medical radiation physics, vol 1. Plenum Press, New York London, pp 103–132Google Scholar
  165. Curran RC, Jones EL (1978) Hodgkin’s disease: an immuno-histochemical and histological study. J Pathol 115: 45–50Google Scholar
  166. D’Angio GJ (1983) Meeting of Orlando (1982) Symposium on magna-field irradiation: rationale, technique, results. Int J Radiat Oncol Biol Phys 9: 1905–1973Google Scholar
  167. Dancot H (1967) Über die Heilungsaussichten bei Lymphosarkomen und Retikulosarkomen durch Bestrahlung (Ergebnisse einer Untersuchung bei 395 Fällen). Deutscher RöntgenkongreB 1966, Teil B, Strahlenbehandlung und Strahlenbiologie. Sonderbände zur Strahlenther 64: 283Google Scholar
  168. Dancot H, Feremans W (1974) The curability of lympho-and reticulosarcomas. In: Musshoff K (ed) Recent results in cancer research, vol 46. Springer, Berlin Heidelberg New York, pp 201–205Google Scholar
  169. De The (1982) Epidemiology of Epstein-Barr virus and associated diseases. In: Roizman B (ed) The Herpes viruses. Plenum Press, New YorkGoogle Scholar
  170. De Vita VT (1973) Combined drug treatment of Hodgkin’s disease — Remission induction, remission duration and survival — an appraisal. Natl Cancer Inst Monogr 36: 373–379Google Scholar
  171. De Vita VT (1973) Lymphocyte reactivity in Hodgkin’s disease: a lymphocyte civil war. N Engl J Med 289: 801–802CrossRefGoogle Scholar
  172. De Vita VT (1977) Summary of symposium. Cancer Treatm Rep 61: 1223–1227Google Scholar
  173. De Vita VT (1981) The consequences of the chemotherapy of Hodgkin’s disease. The 10th David A. Karnofsky Memorial Lecture. Cancer 47: 1–13CrossRefGoogle Scholar
  174. De Vita VT, Hellman S (1982) Hodgkin’s disease and the non-Hodgkin’s lymphomas. In: De Vita VT, Hellman S, Rosenberg StA (eds) Cancer: principles and practice of oncology. Lippincott, Philadelphia, pp 1331–1401Google Scholar
  175. De Vita VT, Canellos CP, Chabner B, Schein P, Hubbard SP, Young RC (1975) Advanced diffuse histiocytic lymphoma, a potentially curable disease. Results with combination chemotherapy. Lancet I: 248–250Google Scholar
  176. De Vita VT, Simon RM, Hubbard SM, Young RC, Berard CW, Moxly JH, Frei III E, Carbone PP, Canellos GP (1980) Curability of advanced Hodgkin’s disease with chemotherapy. Ann Intern Med 92: 587–595Google Scholar
  177. De Vroome H (1982) Summary of the discussion of multiple parallel beams, biological problems and hot spots in critical organs. J Eur Radiother 3: 251Google Scholar
  178. Deeg HJ, Flournoy N, Sullivan KM, Sheehan K, Buckner D, Sanders JE, Storb R, Witherspoon RP, Thomas ED (1984) Cataracts after total body irradiation and marrow transplantation: a sparing effect of dose fractionation. Int J Radiat Oncol Biol Phys 10: 957–964PubMedCrossRefGoogle Scholar
  179. Del Regato JA (1973) Total body irradiation in the treatment of chronique lymphogenous leukemias (Janeway Lecture). Am J Roentgenol 120: 504–520Google Scholar
  180. Delbrück H, Wetter O, Schmidt CG, Weichert HC, Schmitt G (1977) Die Meningosis neoplastica und ihre Prophylaxe bei malignen Non-Hodgkin-Lymphomen. Dtsch Med Wschr 102: 14461451Google Scholar
  181. Delbrück H, Weichert HC, Schmitt G, Firusian N, Wetter 0 (1978) Der Zusammenhang zwischen Prognose und Kieler Klassifikation der malignen Non-Hodgkin-Lymphome. Klin Wschr 56: 539–543Google Scholar
  182. Desser RK, Golomb HM, Ultmann JE, Ferguson DJ, Moran EM, Griem ML, Vardiman J, Miller B, Oetzel N, Sweet D, Kinzie JJ, Blough R (1977) Prognostic classification of Hodgkin disease in pathologic stage III, based on anatomic considerations. Blood 49: 883–893PubMedGoogle Scholar
  183. Diamond LW, Braylan RC (1980) Flow analysis of DNA content and cell size in non-Hodgkin’s lymphoma. Cancer Res 40: 703–712PubMedGoogle Scholar
  184. Diamond LW, Nathwani BN, Rappaport H (1982) Flow cytometry in diagnosis and classification of malignant lymphoma and leukemia. Cancer 50: 1122–1135PubMedCrossRefGoogle Scholar
  185. Diehl V, Kirchner HH, Schaadt M, Fonatsch C, Stein H, Gerdes J, Boie C (1981) Hodgkin’s disease: establishment and characterization of four in vitro cell lines. J Cancer Res Clin On-col 101: 111–124CrossRefGoogle Scholar
  186. Diehl V, Burrichter H, Schaadt M, Kirchner HH, Fonatsch Chr, Stein H, Gerdes J, Heit W, Ziegler A (1983) Hodgkin’s cell lines: characteristics and possible pathogenetic implications. Hematol Oncol 1: 139–147PubMedCrossRefGoogle Scholar
  187. Doll R, Payne P, Waterhouse J (1966) Cancer incidence in five continents. A technical report. Int Union Against Cancer. Springer, BerlinGoogle Scholar
  188. Donaldson SS, Kaplan HS (1982) A survey of pediatric Hodgkin’s disease at Stanford University: Results of therapy and quality of survival. In: Rosenberg SA, Kaplan HS (eds) Malignant lymphomas: Etiology, Immunology, Pathology, Treatment. New York: Academic Press:571–950Google Scholar
  189. Donaldson SS, Kun LE (1983) Magna-field irradiation: a note of caution. Int J Radiat Oncol Biol Phys 9: 1973–1974PubMedGoogle Scholar
  190. Dorfman RF (1971) Relationship of histology to site in Hodgkin’s disease. Cancer Res 31: 1786–1793PubMedGoogle Scholar
  191. Dorfman RF (1974) Classification of non-Hodgkin’s lymphomas. Lancet 1:1295–1296 Dorfman RF (1977) Pathology of the non-Hodgkin’s lymphomas: new classifications. Cancer Treatm Rep 61: 945–951Google Scholar
  192. Dorfman RF, Colby TV (1982) The pathologist’s role in the management of patients with Hodgkin’s disease. Cancer Treatm Rep 66: 675–680Google Scholar
  193. Dühmke E (1976) Zur klinischen Relevanz der histologischen Differenzierungen maligner NonHodgkin-Lymphome nach der „Kiel-Klassifikation“. Eine retrospektive Studie entsprechender Korrelationen bei 228 Fällen aus Schleswig-Holstein. Strahlenther 152: 129–139Google Scholar
  194. Dühmke E (1985) Diskussionsbeitrag auf dem Deutsch-Österreichischen Hämatologenkongreß 1985, WienGoogle Scholar
  195. 1304.
    K. MusshoffGoogle Scholar
  196. Dühmke E, Quäck J (1977) Retrospektive Analyse von malignen Non-Hodgkin-Lymphomerkrankungen der Radiologischen Klinik der Universität Kiel von 1969–1975. Strahlenther 153: 229–231Google Scholar
  197. Dühmke E, Schwarze EW (1981) Therapie der malignen Lymphome des Oropharinx. HNO 29: 302–307PubMedGoogle Scholar
  198. Dühmke E, Brix F, Hebbinghaus D, Jensen M, Schmitz N, Wendhausen H (1985) Fraktionierte homogene Ganzkörperbestrahlung vor Knochenmarktransplantation. Strahlenther 161: 134–139Google Scholar
  199. Durkowsky J, Krajci M (1972) Complications after radiation treatment in Hodgkin’s disease. Neoplasma 19: 227–233Google Scholar
  200. Dutreix A, Broerse JJ (1982) Summary of round table discussion on physical aspects of total body irradiation. J Eur Radiother 3: 262–264Google Scholar
  201. Dutreix J (1984) Toward a biological basis for treatment planning. 8th Conf Comp Rad Therapy, Toronto (1984) IEEE: 4–10Google Scholar
  202. Dutreix J, Gluckmann E, Brule JM (1982) Biological problems of total body irradiation. J Eur Radiother 3: 165–173Google Scholar
  203. Easson EC, Russel MH (1963) The cure of Hodgkin’s disease. Br Med J 1: 1704–1707PubMedCrossRefGoogle Scholar
  204. Edelson RL (1975) Cutaneous T cell lymphomas, perspective (NIH Conference). Ann Intern Med 83: 568Google Scholar
  205. Ekelund H, Kulander S, Källen B (1970) Major and minor malformations in newborns and infants up to one year of age. Acta Radiat Scand 59: 297–302CrossRefGoogle Scholar
  206. Eiff AW von (1986) Die Güterabwägung in Diagnostik und Therapie. Renovatio (im Druck) Ellermann U, Bang 0 (1908) Experimentelle Leukämie bei Hühnern. Zbl Bakt 46: 595–609Google Scholar
  207. Endrizzi L, Fiorentino MV, Sarvagno L, Segall R, Pappagallo GL, Fosser V (1982) Serum lactate dehydrogenase ( LDH) as a prognostic index for non-Hodgkin’s lymphoma. Eur J Cancer Clin Oncol 18: 945–949Google Scholar
  208. Engel St (1926) Die Topographie der bronchialen Lymphknoten. Klin Wschr (Berlin) 5: 1136CrossRefGoogle Scholar
  209. Epstein EH Jr, Levin DL, Croft JD, Lutzner MA (1972) Mycosis fungoides, survival, prognostic features, response to therapy and autopsy findings. Medicine 15: 61–72CrossRefGoogle Scholar
  210. Evans RG (1983) Radiobiological considerations in magna-field irradiation. Int J Radiat Oncol Biol Phys 9: 1907–1911PubMedGoogle Scholar
  211. Faget GB (1979) Mechanisms of lymphocyte activation. The role of suppressor cells in the proliferative response of chronic lymphatic leukemia lymphocytes. J Clin Invest 63: 67–74CrossRefGoogle Scholar
  212. Fagraeus A (1948) Antibody production in relation to the development of plasma cells. In vivo and in vitro experiments. Acta med stand Suppl 204: 1–122Google Scholar
  213. Falk LA, Wolfe LG, Deinhard F (1971) Oncogenesis of Herpes virus saimiri in marmosets. Fed Proc 30: 514Google Scholar
  214. Farber LR, Prosnitz LR, Cadman DC (et al.) (1980) Curative potential of combined modality therapy for advanced Hodgkin’s disease. Cancer 46: 1509–1517Google Scholar
  215. Farhangi M, Ossermann EF (1973) The treatment of multiple myelomy. Sem Hematol 10: 149–161Google Scholar
  216. Fefer A, Cheever MA, Boyd C, Ramberg R, Appelbaum FR, Kaplan HG, Greenberg PD, Buckner CD, Sanders J, Storb R, Thomas ED (1981) Clinical and cytogenetic complete remission (CR) in 12 CML patients after chemotherapy and identical twin bone marrow transplantation. Proc Am Ass Cancer Res & Am Soc Clin Oncol 22:492, Abstr 622Google Scholar
  217. Ferraris AM, Giuntini P, Gaetani GF (1979) Serum lactic dehydrogenase as a prognostic tool for non-Hodgkin lymphomas. Blood 54: 928–932PubMedGoogle Scholar
  218. Fialkow PJ (1979) Use of glucose-6-phosphate dehydrogenase markers to study human myeloproliferative disorders. In: Neth R, Gallo RC, Hofschneider PH, Mannweiler K (eds) Modern trends in human leukemia, vol III. Springer, Berlin Heidelberg New York, pp 53–58CrossRefGoogle Scholar
  219. Fialkow PJ, Denman AM, Singer J, Jacobson RJ, Lowenthal MN (1978) Human myeloproliferative disorders: clonal origin in pluripotent stem cells. In: Clarkson B (ed) Differentiation of normal and neoplastic hematopoietic cells. Cold Spring Harbor Laboratory, Cold Spring Harbor, pp 131–144Google Scholar
  220. Fialkow PJ, Jacobson RJ, Singer JW, Sacher RA, McGuffin RW, Neefe JR (1980) Philadelphia chromosome (Ph’)-negative chronic myelogenous leukemia (CML): a clonal disease with origin in a multipotent stem cell. Blood 56: 70–73PubMedGoogle Scholar
  221. Fischer R, Krüger G (1981) Probleme der histologischen Klassifizierung und Differentialdiagnose des Morbus Hodgkin. Internist 22: 255–263PubMedGoogle Scholar
  222. Fisher RI, DeVita VT Jr, Hubbard SM, Longo DL, Wesley R, Chabner BA, Young RC (1983) Diffuse aggressive lymphomas: increased survival after alternating flexible sequences of Pro-MACE and MOPP chemotherapy. Ann Intern Med 98: 304–309PubMedGoogle Scholar
  223. Foucar K, McKenna RW, Frizzera G, Brunning RD (1979) Incidence and patterns of bone marrow and blood involvement by lymphoma in relationship to the Lukes-Collins classification. Blood 54: 1417–1422PubMedGoogle Scholar
  224. Fransilla KO, Kalima TV, Voutilainen A (1967) Histological classification of Hodgkin’s disease. Cancer (Philad) 20: 1594–1601CrossRefGoogle Scholar
  225. Freeman AI, Weinberg VE, Brecher ML, Jones R, Glicksman A (1982) Comparison of intermediate dose methotrexate (IDM) with cranial irradiation (CRT) in acute lymphocytic leukemia (ALL). Am Soc Clin Oncol 1:130 AbstrGoogle Scholar
  226. Freeman HL, Weinstein WM, Shnitka TK, Piercey JRA, Wensel RH (1977) Primary abdominal lymphoma. Presenting manifestation of celiac sprue or complicating dermatitis herpetiformis. Am J Med 63: 585–594Google Scholar
  227. Freeman JE, Johnston PGB, Voke JM (1973) Somnolence after prophylactic cranial irradiation in children with acute lymphoblastic leukaemia. Br Med J IV: 523Google Scholar
  228. Frei E, Luce JK, Gamble JF, Coltman CA, Constanzi JJ, Talley RW, Monto RW, Wilson HE, Hewlett JS, Delaney FC, Gehan EA (1973) Combination chemotherapy in advanced Hodgkin’s disease. Ann Intern Med 79: 376–382PubMedGoogle Scholar
  229. Frei III E, Freireich EJ (1965) Progress and perspectives in the chemotherapy of acute leukemia. Adv Chemother 2: 269PubMedGoogle Scholar
  230. Frei III E, Sallan SE (1978) Acute lymphoblastic leukemia: treatment. Cancer 42: 828–838PubMedCrossRefGoogle Scholar
  231. Freund M, Ostendorf P, Gärtner VH, Waller HD (1983) CNS manifestations in non-Hodgkin lymphomas ( NHL ). Klin Wschr 61: 903–909Google Scholar
  232. Friedmann G, Beyer D (1985) Diagnostische Probleme beim Rezidiv der Lymphogranulomatose. Strahlenther 161: 203–207Google Scholar
  233. Friedmann G, Peters PE, Beyer D (1981) Rationelle Diagnostik der Lymphogranulomatose durch gestuften Einsatz bildgebender Verfahren. Internist 22: 270–277PubMedGoogle Scholar
  234. Fülle HH (1977) Induktions-und Erhaltungstherapie der akuten myeloischen Leukämie des Erwachsenen durch sequentiale Anwendung zytostatischer Therapie-Kombinationen. Med Klin 72: 642PubMedGoogle Scholar
  235. Fülle HH, Bartels H, Brittinger G, Common H, Dühmke E, Gunzer U, Heinz R, König E, Meusers P, Paukstat M, Pralle H, Theml H, Lennert K, Schwarze EW, Köpcke W, Zwingers T, Musshoff K, Stacher A, Brücher H, Oertel J, Pees HW (für die Kieler Lymphomgruppe) (1984) Das T-Zonen-Lymphom. In: Diehl V, Sack H (Hrsg) Diagnostik und Therapie der Non-Hodgkin-Lymphome. Aktuelle Onkologie, Bd XII. Zuckschwerdt, München, S 121-126Google Scholar
  236. Fuks Z, Bagshaw MA (1971) Total-skin electron treatment of mycosis fungoides. Radiology 100: 145–150PubMedGoogle Scholar
  237. Fuks Z, Bagshaw MA, Farber EM (1973) Prognostic signs and the management of the mycosis fungoides. Cancer 32: 1385–1395PubMedCrossRefGoogle Scholar
  238. Fuks Z, Glatstein E, Kaplan HS (1975) Patterns of presentation and relapse in the non-Hodgkin’s lymphomata. Br J Cancer 31, Suppl I1: 286–297Google Scholar
  239. Fuks Z, Strober S, Bobrove AM, Sasazuki T, McMichael A, Kaplan HS (1976) Long terms effects of radiation on T and B lymphocytes in peripheral blood patients with Hodgkin’s disease. J Clin Invest 58: 803–814PubMedCrossRefGoogle Scholar
  240. Fuller LM, Gamble JF, Butler JJ (1971) Influence of specific histology and clinical presentation on prognosis in localized Hodgkin’s disease treated with intensive large volume radiotherapy. J Radiol 98: 641–654Google Scholar
  241. Fuller LM, Hagemeister FB, Cunha M da (1983) Treatment of laparotomy-staged I and II Hodgkin’s disease. In: Ford RJ, Fuller LM, Hagemeister FB (eds) UT MD Anderson Clinical Conference on Cancer 27. Raven Press, New York, pp 71–82Google Scholar
  242. Fuller LM, Madoc-Jones H, Hagemeister FB et al. (1980) Further follow-up of results of treatment in 90 laparotomy-negative stage I and II Hodgkin’s disease patients: significance of mediastinal and non-mediastinal presentations. Int J Rad Oncol Biol Phys 6: 799–808CrossRefGoogle Scholar
  243. Fuller LM, Madoc-Jones H, Gamble JF, Butler JJ, Sullivan MP, Fernandez CH, Gehan EA (1977) New assessment of the prognostic significance of histopathology in Hodgkin’s disease for laparotomy negative stage I and II patients. Cancer 39: 2174–2182PubMedCrossRefGoogle Scholar
  244. Fuller LM, Gamble JF, Valasquez WS, Rodgers RW, Butler JJ, Worth LB, Martin RG, Gehan EA, Shullenberger CC (1980) Evaluation of the significance of prognostic factors in stage III Hodgkin’s disease treated with MOPP and radiotherapy. Cancer 45: 1352–1364PubMedCrossRefGoogle Scholar
  245. Gahrton G, Lindsten J, Zech L (1973) Origin of the Philadelphia chromosome: tracing of chro- mosome 22 to parents of patients with chronic myelocytic leukemia. Exp Cell Res 70: 246CrossRefGoogle Scholar
  246. Galton DAG (1982) The chronic leukaemias. In: Hardisty RM, Weatherall DJ (eds) Blood and its disorders, 2nd ed. Blackwell, Oxford, pp 877–917Google Scholar
  247. Galton DAG, Goldman JM, Wiltshaw E, Catovsky D, Henry K, Goldenberg GJ (1974) Prolymphocytic leukaemia. Br J Haemat 27: 7–23CrossRefGoogle Scholar
  248. Galvin JM (1983) Calculation and prescription of dose for total body irradiation. Int J Radiat Oncol Biol Phys 9: 1919–1924PubMedGoogle Scholar
  249. Galvin JM, D’Angio GJ (eds) (1980) Meeting of Montreal (1979) Children’s Cancer Study Group, the radiation therapy committee: the physics and clinical aspects of total body irradiation used for bone marrow transplantation. Int J Radiat Oncol Biol Phys 6: 743–787Google Scholar
  250. Garrett JV, Scarffe JH, Newton RK (1979) Abnormal peripheral blood lymphocytes and bone marrow infiltration in non-Hodgkin’s lymphoma. Br J Haemat 42: 41–50CrossRefGoogle Scholar
  251. Garwicz S, Landberg T, Lindgberg L-G, Akerman M (1978) Clinicopathological correlations in the Kiel classification of non-Hodgkin’s lymphomata in children. Scand J Haemat 20: 171–180PubMedCrossRefGoogle Scholar
  252. Garwin AJ, Spicer SS, Parmley RT, Munster AM (1974) Immunohistochemical demonstration of IgG in Read-Sternberg-and other cells in Hodgkin’s disease. J Exp Med 139: 1077–1083CrossRefGoogle Scholar
  253. Georgi A (1979) Classification of non-Hodgkin lymphomas from biopsies of the bone marrow with special emphasis to their spread. In: Canonico A, Estevez O, Chacon R, Barg, S (eds) Advances in Medical Oncology, Research and Education, vol VII. Pergamon, Oxford, pp 179–188Google Scholar
  254. Georgii A (1983) Histopathologie und Klinik der chronischen, myeloproliferativen Erkrankungen. Verh Dtsch Ges Pathol 67: 214–234PubMedGoogle Scholar
  255. Georgii A (1985) Chronische myeloproliferative Erkrankungen. In: Gross R, Schmidt CG (Hrsg) Klinische Onkologie. Thieme, Stuttgart New York, S 13. 1–20Google Scholar
  256. Georgii A, Vykoupil KF (1972) Pathologische Anatomie der megakaryocytären Myelose. In: Gross R, van de Loo J (Hrsg) Leukämie. Springer, Berlin Heidelberg New York, S 25–28Google Scholar
  257. Georgii A, Vykoupil KF, Thiele J (1980) Chronic megakaryocytic granulocytic myelosis–CMGM–A subtype of chronic myeloid leukemia. Virchows Arch A 389: 253–268Google Scholar
  258. Georgii A, Vykoupil KF, Thiele J (1984) Classification of chronic myeloproliferative disease by bone marrow biopsies. Hematological and cytogenetic findings and clinical course. Bibl Haemat 50: 41–56Google Scholar
  259. Georgii A, Vykoupil KF, Thiele J (1984) Histopathology of bone marrow and clinical findings in chronic myeloproliferative disease. In: Lennert K, Hübner K (eds) Pathology of the bone marrow. Fischer, Stuttgart, pp 147–169Google Scholar
  260. Gérard-Marchant R, Hamlin I, Lennert K, Rilke F, Stansfeld AG, van Unnik JAM (1974) Classification of non-Hodgkin’s lymphomas. Lancet 11: 406–408Google Scholar
  261. Gerdes J, Schwab U, Lemke H, Stein H (1983) Production of a mouse monoclonal antibody reaktive with a human antigen associated with cell proliferation. Int J Cancer 31: 13PubMedCrossRefGoogle Scholar
  262. Gerdes J, Dallenbach F, Lennert K, Lemke H, Stein H (1984) Proliferation rates in malignant non-Hodgkin’s lymphomas as determined in situ with the monoclonal antibody Ki-67. Hematol Oncol 2: 365–371PubMedGoogle Scholar
  263. Gilbert R (1939) Radiotherapy in Hodgkin’s disease (malignant granulomatosis): anatomic andGoogle Scholar
  264. clinical foundations; governing principles; results. Am J Roentgenol 41:198–241Google Scholar
  265. Gilbert R, Babaiantz L (1931) Notre méthode de roentgenthéraphie de la lymphogranulomatose ( Hodgkin); résultats éloignés. Acta Radiol (Stockh) 12: 523–529Google Scholar
  266. Gilchrest BA, Parrish JA, Tanenbaum L, Haynes HA, Fitzpatrick ThB (1976) Oral methoxalen photochemotherapy of mycosis fungoides. Cancer 38: 683–689PubMedCrossRefGoogle Scholar
  267. Glaeser L (1986) Influence of lung tissue on the dose distribution of high energy photon beams, review. Strahlenther 162: 266–270Google Scholar
  268. Glasgow GP (1982) The dosimetry of fixed, single source hemibody and total body irradiators. Med Phys 9: 311–323PubMedCrossRefGoogle Scholar
  269. Glatstein E, Guernsey IM, Rosenberg SA, Kaplan HS (1969) The value of laparotomy and splenectomy in the staging of Hodgkin’s disease. Cancer (Philad) 24: 709–718CrossRefGoogle Scholar
  270. Glatstein E, Fuchs E, Goffinet DR, Kaplan HS (1976) Non-Hodgkin’s lymphoma of stage IIIGoogle Scholar
  271. extent. Is total lymphoid irradiation appropriate treatment? Cancer 37: 2806–2812Google Scholar
  272. Glatstein E, Donaldson SS, Rosenberg SA, Kaplan HS (1977) Combined modality therapy in malignant lymphomas. Cancer Treatm Rep 61: 1199–1207Google Scholar
  273. Glatstein E, Portlock C, Rosenberg SA, Kaplan HS (1977) Combined modality treatment in the malignant lymphomas. In: Salmon SE, Jones SE (eds) Adjuvant therapy of cancer. North-Holland Publishing Co., Amsterdam, pp 545–548Google Scholar
  274. Glimelius B, Hagberg H, Sundström C (1983) Morphological classification of non-Hodgkin malignant lymphoma. II. Comparison between Rappaport’s classification and the Kiel classification. Scand J Haemat 30: 13–24Google Scholar
  275. Glimelius B, Sundström C (1983) Morphological classification of non-Hodgkin’s lymphoma. I. Retrospective analysis using the Kiel classification. Acta Radiol 21: 289–297Google Scholar
  276. Gluckmann E, Barrett AJ (1980) European results of bone marrow transplantation. Blut 41: 154–157Google Scholar
  277. Goffinet DR, Castellino RA, Kim H, Dorfman RF, Fuks Z, Rosenberg SA, Nelson T, Kaplan HS (1973) Staging laparatomy in unselected previously untreated patients with non-Hodgkin’s lymphomas. Cancer (Philad) 32: 672–691CrossRefGoogle Scholar
  278. Goffinet DR, Glatstein E, Funks Z, Kaplan HS (1976) Abdominal irradiation in non-Hodgkin’s lymphomas. Cancer 37: 2797–2806PubMedCrossRefGoogle Scholar
  279. Golde DW (1982) Therapy of hairy-cell leukemia. N Engl J Med 307: 495–496PubMedCrossRefGoogle Scholar
  280. Goldie JH, Coldman AJ (1979) A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate. Cancer Treatm Rep 63: 1727–1733Google Scholar
  281. Goldin A, Vendetti JM, Humphreys SR, Mantel N (1956) Influence of the concentration of leukemia inoculum on the effectiveness. Science 123: 840PubMedCrossRefGoogle Scholar
  282. Goldin A, Vendetti JM, Humphreys SR, Mantel N (1958) Quantitative evaluation of the chemo-Google Scholar
  283. therapy agents against advanced leukemia in mice. J Natl Cancer Inst 21:495–511Google Scholar
  284. Goldin A, Sandberg S, Henderson ES, Newman JW, Frei III E, Holland JF (1971) The chemotherapy of human and animal acute leukemia. Cancer Chemother Rep 55: 309PubMedGoogle Scholar
  285. Goldin A et al. (1956) J Natl Cancer Inst 17: 203PubMedGoogle Scholar
  286. Gospodarowicz MK, Bush RS, Brown TC, Chua T (1984) Prognostic factors in nodular lymphomas. Int J Radiat Oncol Biol Phys 10: 489–497PubMedCrossRefGoogle Scholar
  287. Gospodarowicz MK, Sutcliffe S, Bush RS, Brown TC (1984) Patterns of disease in extranodal non-Hodgkin’s lymphoma - indirect evidence supporting “homing”. In: Proc Second Intern Conf Malignant Lymphoma. Current Status and Prospects, Lugano. Nijhoff, Den HaagGoogle Scholar
  288. Gough J (1970) Hodgkin’s disease, a correlation of histopathology with survival. Int J Cancer 5: 273–281PubMedCrossRefGoogle Scholar
  289. Graeves MF (1983) Immunobiology of lymphoid malignancy. In: Neth R, Gallo RC, Graeves MF, Moore MAS, Winkler K (eds) Modern trends in human leukemia. V. Hematology and blood transfusion, vol XXVIII. Springer, Berlin Heidelberg New York, pp 3–10Google Scholar
  290. Gray JL, Jacobs A, Bloc M (1974) Bone marrow and peripheral blood lymphocytosis in the prognostic of chronic lymphocytic leukemia. Cancer 33: 1669–1778CrossRefGoogle Scholar
  291. Gronowitz JS, Hagberg H, Källander CFR, Simonsson B (1983) The use of serum deoxythymidine kinase as a prognostic marker, and in the monitoring of patients with non-Hodgkin’s lymphoma. Br J Cancer 47: 487–495PubMedCrossRefGoogle Scholar
  292. Grosch-Wörner J, Langermann HJ, Brämswig J, Henze G, Odenwald E, Ritter J, Schellong G, Riehm H (1983) Behandlungsergebnisse mit Kindern mit akuter lymphoblastischer Leukämie nach isoliertem Knochenmarkrezidiv. (Nicht veröffentlichtes Manuskript)Google Scholar
  293. Gross R, Hirschmann WD (1985) Akute Leukämien In• Gross R, Schmidt CG (Hrsg) Klinische Onkologie. Thieme, Stuttgart New York, S 42. 1–37Google Scholar
  294. Gross R, Schulten HK, Zach J (1968) Die Leukämie der Erwachsenen. Eine klinisch-statistische Übersicht anhand von 1200 Fällen. Internist 9: 476–483Google Scholar
  295. Grozea PN, Jones SE, McKelvey EM, Coltman CA Jr, Fisher R, Haskins CL (1979) Combination chemotherapy for mycosis fungoides: a southwest oncology group study. Cancer Treatm Rep 63: 647–653Google Scholar
  296. Gruenwald HW, Rosner F (1982) Acute myeloid leukemia following treatment of Hodgkin’s disease: a review. Cancer 50: 676–683CrossRefGoogle Scholar
  297. Günther C, Helbig W, Puschel W, Hofmann F-A (1982) Zum Stellenwert der Beckenkamm-Histobiopsie bei der Diagnostik maligner Lymphominfiltrate im Knochenmark. Z Ges Inn Med 37: 445–453PubMedGoogle Scholar
  298. Gunzer U, Bartels H, Burger A, Common H, Dabag S, Fülle HH, Huhn D, Leopold H, Löffler H, Nowicki K, Vogt W, Waldner R (Kieler Lymphomgruppe) (1979) Klinik und Prognose des lymphoblastischen Lymphoms. In: Stacher A, Höcker P (Hrsg) Lymphknotentumoren, Pathophysiologie, Klinik und Therapie. Urban & Schwarzenberg, München, S 229–233Google Scholar
  299. Gupta S, Good RA (1977) Subpopulations of human T lymphocytes. II. Effects of thymopoietin, corticosteroids and irradiation. Cell Immunol 34: 10–18Google Scholar
  300. Gupta S, Good RA (1979) Subpopulations of human T lymphocytes. III. Distribution and quantitation in peripheral blood, cord blood, tonsils, bone marrow, thymus lymph nodes and spleen. Cell Immunol 36: 263–276Google Scholar
  301. Habeshaw JA, Lister TA, Stansfeld AG, Greaves MF (1983) Correlation of transferrin receptor expression with histological class and outcome in non-Hodgkin lymphoma. Lancet 1: 498–501PubMedCrossRefGoogle Scholar
  302. Hagberg H, Glimelius B, Sundstrom C (1982) Radiation therapy of non-Hodgkin’s lymphomas stages I and II. Acta Radiologica 21: 145–150CrossRefGoogle Scholar
  303. Hagberg H, Killander A, Simonsson B (1983 a) Serum ß2-microglobulin in malignant lymphoma. Cancer (Philad) 51: 2220–2225Google Scholar
  304. Hagberg H, Siegbahn A (1983 b) Prognostic value of serum lactic dehydrogenase in non-Hodgkin’s lymphoma. Scand J Haemat 31: 49–56Google Scholar
  305. Hagemeister FB, Fuller LM, Velesquez WS, Sullivan JA, North L, Butler JJ, Johnston DA, Shullenberger CC (1982) Stage I and II Hodgkin’s disease: involved-field radiotherapy versus extended field radiotherapy versus involved-field radiotherapy followed by six cycles of MOPP. Cancer Treatm Rep 66: 789–798Google Scholar
  306. Hall EJ (1978) Radiobiology for the radiologist. Harper & Row, Hagertown MDGoogle Scholar
  307. Hamburger A, Salmon SE (1977) Primary bioassay of human myeloma stem cells. J Clin Invest 60: 846–854PubMedCrossRefGoogle Scholar
  308. Han T, Stutzmann K (1967) Mode of spread in patients with localized malignant lymphoma. Arch Intern Med 120: 1–7PubMedCrossRefGoogle Scholar
  309. Hansmann ML, Kaiserling E (1981) Electron-microscopic aspects of Hodgkin’s disease. Clin Oncol 101: 135–148Google Scholar
  310. Hansmann ML, Zwingers T, Böske A, Löffler H, Lennert K (1984) Clinical features of nodular paragranuloma ( Hodgkin’s disease, lymphocytic predominance type, nodular ). J Cancer Res Clin Oncol 108: 321–330Google Scholar
  311. Hartwich G, König HJ, von Roemeling R (1982) Therapiemöglichkeiten bei gastrointestinalen Lymphomen. In: Scheurlen PG, Pees HW (Hrsg) Aktuelle Therapie bösartiger Blutkrankheiten. Springer, Berlin Heidelberg New York, S 241–243Google Scholar
  312. Heckemann R (1983) Sonographische Tumordiagnostik im Retroperitoneum. Therapiewoche 33: 123–137Google Scholar
  313. Hedges MJ, Homey S (1978) The effects of X-rays and neutrons on lymphocyte death and transformation. Int J Radiat Biol 33: 291–300CrossRefGoogle Scholar
  314. Heinz R, Stacher A, Pralle H, Theml H, Brunswicker F, Burkert M, Common H, Fülle HH, Grisar T, Grüneisen A, Herrmann F, Leopold H, Liffers R, Meusers P, Nowicki L, Nürnberger R, Rengshausen H, Rühl U, Schoengen A, Schmidt M, Wirthmüller R, Schwarze EW, Brittinger G (Kiel Lymphoma Study Group) (1981) Lymphoplasmacytic/lymphoplasmocytoid lymphoma: a clinical entity distinct from chronic lymphocytic leukaemia? Blut 43: 183–192CrossRefGoogle Scholar
  315. Helbron D, Brittinger G, Lennert K (1979) T-Zonen-Lymphom - Klinisches Bild, Therapie und Prognose. Blut 39: 117–131Google Scholar
  316. Hellman S, Rosenthal DS, Molonney WC, Chaffry JT (1975) The treatment of non-Hodgkin’s lymphoma. Cancer 36: 804–808PubMedCrossRefGoogle Scholar
  317. Hellman S, Chaffrey JT, Rosenthal DS, Molonay WC, Canellos GP, Skarin AT (1977) The place of radiation therapy in the treatment of non-Hodgkin’s lymphomas. Cancer 39: 843–851PubMedCrossRefGoogle Scholar
  318. Hellman S, Mauch P, Goodman RL, Rosenthal DS, Molonney WC (1978) The place of radiation therapy in the treatment of Hodgkin’s disease. Cancer 42: 971–978PubMedCrossRefGoogle Scholar
  319. Henze G, Langermann HJ, Gadner H, Schllong G, Welte K, Riehm H (1981) Ergebnisse der Studie BFM 76/79 zur Behandlung der akuten lymphoblastischen Leukämie bei Kindern und Jugendlichen. Klin Pädiatr 193: 28CrossRefGoogle Scholar
  320. Heumann R, Panahon AM, Barcos MP, Walsh D, Stutzman L (1980) Gastrointestinal involvement in non-Hodgkin’s lymphoma. Cancer 46: 215–222CrossRefGoogle Scholar
  321. Hersey P, Wotherspoon J, Reid J, Gunz FW (1980) Hypogamma globulinemia associated with abnormalities of both B and T lymphocytes in patients with chronic lymphatic leukemia. Clin Exp Immunol 39: 698–707PubMedGoogle Scholar
  322. Herzog P (1983) Retroperitoneale Lymphknoten. In: Braun, Günther, Schwerk (Hrsg) Ultraschalldiagnostik. Ecomed, Landsberg/Lech, III-1. 6Google Scholar
  323. Hewer TF (1937) Megakaryocytic myelosis with osteosclerosis. J Path Bact 45: 383–390CrossRefGoogle Scholar
  324. Hirschmann WD, Gerecke D, Hellriegel KP, Voigtmann R, Borberg H, Gauwerky C, Glöckner W, Gross R (1978) Behandlungsresultate akuter Leukosen des Erwachsenen: Erstremissionsrate, Remissionsdauer, Remissionserhaltung. Prognose des Rezidivs. Verh Dtsch Ges Inn Med 84: 151Google Scholar
  325. Hoagland HC, Silverstein MN (1978) Primary thrombocythemia in the young patients. Mayo Clin Proc 53: 578–580PubMedGoogle Scholar
  326. Hodgkin T (1832) On some morbid appearances of the absorbent gland and spleen. Med-Chir Trans 17: 68–114PubMedGoogle Scholar
  327. Hoelzer D, Thiel E, Löffler H, Bodenstein H, Plaumann L, Büchner Th, Urbanitz D, Koch P, Heimpel H, Engelhard R, Müller U, Wendt FC, Sodomann H, Rühl H, Herrmann F, Ka-both W, Dietzfelbinger H, Pralle H, Lunscken Ch, Hellriegel KP, Spors S, Nowrousian MR, Fischer J, Fülle HH, Mitrou P, Pfreundschuh M, Görg Ch, Emmerich B, Queisser W, Meyer P, Labedzki L, Essers U, König H, Mainzer K, Herrmann R, Messerer D, Zwingers Th (1983) Patientenrekrutierung und Ergebnisse einer Vorphasenstudie zur Therapie der akuten lymphatischen Leukämie und der akuten undifferenzierten Leukämie des Erwachsenen. Onkol 6: 170–174CrossRefGoogle Scholar
  328. Hoelzer D, Thiel E, Löffler H, Bodenstein H, Plaumann L, Büchner Th, Urbanitz D, Koch P, Ganser A, Engelhardt R, Müller U, Wendt FC, Sodomann H, Rühl H, Herrmann F, Kaboth W, Voswinckel P, Pralle H, Lunscken Ch, Gerecke D, Kress M, Nowrousian MR, Burkert M, Fülle HH, Mitrou P, Ho AD, Görg Ch, Emmerich B, Queisser W, Meyer P, Vaupel HA, König H, Braumann D, Herrmann R, v. Paleske A, Messerer D, Zwingers Th ( 1984 a) Risikoadaptierte Therapie der akuten lymphatischen (ALL) und der akuten undifferenzierten Leukämie (AUL) des Erwachsenen. Verh Dtsch KrebsGes 5:843–846. Fischer, Stuttgart New YorkGoogle Scholar
  329. Hoelzer D, Thiel E, Löffler H, Bodenstein H, Plaumann L, Büchner T, Urbanitz D, Koch P, Heimpel H, Engelhardt R, Müller U, Wendt FC, Sodomann H, Rühl H, Herrmann F, Ka-both W, Dietzfelbinger H, Pralle H, Lunscken C, Hellriegel KP, Spors S, Nowrousian RM, Fischer J, Fülle H, Mitrou PS, Pfreundschuh M, Görg Ch, Emmerich B, Queisser W, Meyer P, Labedzki L, Essers U, König H, Mainzer K, Herrmann R, Messerer D, Zwingers T (1984b) Intensified therapy in acute lymphoblastic and acute undifferentiated leukemia in adults. Blood 64: 38–47PubMedGoogle Scholar
  330. Hönigsmann H, Brenner W, Rauschmeier W, Konrad K, Wolff K (1984) Photochemotherapy for cutaneous T cell lymphoma. A follow-up study. J Am Acad Derm 10: 238–245Google Scholar
  331. Hoppe RT (1980) Radiation therapy in the treatment of Hodgkin’s disease. Semin Oncol 7: 144–154PubMedGoogle Scholar
  332. Hoppe RT (1983) The definite management of limited and intermediate stages of Hodgkin’s disease with radiotherapy alone. In. Bennett JM (ed) Controversies in the management of lymphomas. Nijhoff, Boston The Hague Dordrecht Lancaster, pp 129–150Google Scholar
  333. Hoppe RT, Fuks Z, Bagshaw MA (1977) The rationale for curative radiotherapy in mycosis fungoides. Int J Radiat Oncol Biol Phys 2: 843–851PubMedCrossRefGoogle Scholar
  334. Hoppe RT, Cox RS, Fuks Z, Price NM, Bagshaw MA, Farber EM (1979) Electron-beam therapy for mycosis fungoides: the Stanford University experience. Cancer Treatm Rep 63: 691–700Google Scholar
  335. Hoppe RT, Coleman CN, Kaplan HS et al. (1980) Hodgkin’s disease, pathologic stage I—II. The prognostic importance of initial sites of disease and extent of mediastinal involvement. Proc Am Assoc Cancer Res and ASCO 21: 471Google Scholar
  336. Hoppe RT, Rosenberg SA, Kaplan HS, Cox RS (1980) Prognostic factors in pathological stage III A Hodgkin’s disease. Cancer 46: 1240–1246PubMedCrossRefGoogle Scholar
  337. Hoppe RT, Cox RS, Rosenberg SA, Kaplan HS (1982) Prognostic factors in pathologic stage III Hodgkin’s disease. Cancer Treatm Rep 66: 743–749Google Scholar
  338. Horiuchi J, Okuyama T, Matsubara S, Shibuya H, Suzuki S, Kamiyama R (1982) Extranodal non-Hodgkin’s lymphoma in the head and neck. Acta Radiol Oncol 21: 393–399PubMedCrossRefGoogle Scholar
  339. Horiuchi J, Okuyama T, Matsubara S, Shibuya H, Suzuki S, Kamiyama R (1982) Extranodal non-Hodgkin’s lymphoma in the head and neck. Acta Radiol Oncol 21: 393–399PubMedCrossRefGoogle Scholar
  340. Horning SJ, Rosenberg SA (1984) The natural history of initial untreated low-grade non-Hodgkin’s lymphomas. N Engl J Med 311: 1471–1475PubMedCrossRefGoogle Scholar
  341. Horning SJ, Hoppe RT, Kaplan HS, Rosenberg SA (1981) Female reproductive potential after treatment for Hodgkin’s disease. N Engl J Med 304: 1377–1382PubMedCrossRefGoogle Scholar
  342. Horwich A, Laston D, Nogueira-Costa R, Liew H, Colman M, Peckham MJ (1986) An analysis of prognostic factors in early stage Hodgkin’s disease. Radiotherapy and Oncology 7: 95–106PubMedCrossRefGoogle Scholar
  343. Horwich A, Peckham M (1983) “Bad risk” non-Hodgkin’s lymphoma. Seminars Hematol 20:35–56Google Scholar
  344. Hossfeld DK (1985) Chronische myeloische Leukämie. In: Gross R, Schmidt CG (Hrsg) Klinische Onkologie. Thieme, Stuttgart New York, S 43. 1–18Google Scholar
  345. Huber H, Gattringer C, Thaler J, Peschel Ch (1985) Immunzytologische Diagnose Leukämien und Lymphomen: Monoclonale Antikörper in der Differentialdiagnose hämatologischer Neoplasien. Behring Inst Mitt 78: 83–117Google Scholar
  346. Hübener KH (1985 a) Strahlentherapie der Lymphogranulomatose. Strahlenther 161:208–215Google Scholar
  347. Hübener KH (1985 b) Persönliche MitteilungGoogle Scholar
  348. Hübener KH, Ahlemann LM (1984) Grolle Mantelfelder-Indikation, Technik, Verträglichkeit und Nebenwirkungen. Strahlenther 160: 366–372Google Scholar
  349. Hunt RD, Melendez LV, King NW, Gilmore CE, Daniel MD, Williamson ME, Jones TC (1970) Morphology of a disease with features of malignant lymphoma in maromsets and owl monkeys inoculated with Herpesvirus saimiri. J Nat Cancer Inst 44: 447–453PubMedGoogle Scholar
  350. Hustu HO, Aur RJA, Verzosa MS, Simone JV, Pinkel D (1973) Prevention of central nervous system leukemia by irradiation. Cancer 32: 585–597PubMedCrossRefGoogle Scholar
  351. Hutchinson GB (1976) Survival and complications of radiotherapy following involved and extended field radiotherapy of Hodgkin’s disease stage I and II. A collaborative study. Cancer 38: 288–305CrossRefGoogle Scholar
  352. Jackson H, Parker F (1944) Hodgkin’s disease. II Pathology. N Engl J Med 231: 35–44Google Scholar
  353. Jacquillat C, Auclerc G, Weil M, Auclerc MF, Maval J (1983) Leucemies aigues et tumeurs solides dans l’evolution de la maladie de Hodgkin. Bull Cancer (Paris) 70: 61–66Google Scholar
  354. Jaffe JP, Bosch A, Raich PC (1979) Sequential hemibody radiotherapy in advanced multiple myeloma. Cancer 43: 124–128PubMedCrossRefGoogle Scholar
  355. Jamshidi K, Ansari KA, Windschitl HE, Swaim WR (1973) Primary thrombocythemia. Geniatrics 28: 121–133Google Scholar
  356. Jansen J, Hermans J (Collaborative Study Group) (1981) Splenectomy in hairy cell leukemia: a retrospective multicenter analysis. Cancer 47: 2066–2076CrossRefGoogle Scholar
  357. Janssen JTP, De Pauw BE, Holdrinet RSG (1984) Treatment of hairy-cell leukaemia with recombinant human a-interferon. Lancet L•1025–1026Google Scholar
  358. Jeliffe AM, Thomson AD (1955) The prognosis in Hodgkin’s disease. Br J Cancer 9: 21–36CrossRefGoogle Scholar
  359. Dellinger K (1983) Maligne Lymphome und Leukämien im Zentralnervensystem. Verh Dtsch Ges Pathol 67: 556–573Google Scholar
  360. Jenkin RDT, Anderson JR, Chilcote RR, Coccia PF, Exelby PR, Kersey JH, Kushner JH, Meadows AT, Siegel SE, Sposto R, Wilson JF, Hammond GD (1984) The treatment of localized non-Hodgkin’s lymphoma in children: a report from the children’s cancer study group. J Clin Oncol 2: 88–97PubMedGoogle Scholar
  361. Jereb B, Tann Ch, Bretsky S, He S, Exelby P (1984) Involved field ( IF) irradiation with or without chemotherapy in the management of children with Hodgkin’s disease. Med Pediat Oncol 12: 325–332Google Scholar
  362. Johnson RE (1973) Total nodal irradiation. J Am Med Ass 223: 59–61CrossRefGoogle Scholar
  363. Johnson RE (1979) Treatment of chronic lymphocytic leukemia by total body irradiation alone and combined with chemotherapy. Int J Radiat Oncol Biol Phys 5: 159–164PubMedGoogle Scholar
  364. Johnson RE, Glover MK, Marshall SK (1971) Results of radiation therapy and implications for the clinical staging of Hodgkin’s disease. Cancer Res 31: 1834–1837PubMedGoogle Scholar
  365. Johnson RE, Rühl U (1976) Treatment of chronic lymphocytic leukemia with emphasis on total body irradiation. Int J Radiat Oncol Biol Phys 1: 387–397PubMedCrossRefGoogle Scholar
  366. Johnson RE, Rühl U, Brereton H (1975) Radiation therapy of malignant lymphomas: Rationale techniques, results. Proceedings of the XI. International Cancer Congress, Florence 1974. Excerpta Medica Intern Congr Ser 354: 374–379Google Scholar
  367. Johnson RE, Thomas LB, Chretien P (1970) Correlation between clinicohistologic staging and extranodal relapse in Hodgkin’s disease. Cancer 25: 1071–1075PubMedCrossRefGoogle Scholar
  368. Johnson RE, Rühl U, Johnson SK, Glover M (1976) Split-course radiotherapy of Hodgkin’s disease. Cancer 37: 1713–1717PubMedCrossRefGoogle Scholar
  369. Jones SE (1974) Clinical features and course of the non-Hodgkin’s lymphomas. Clin Haemat 3: 131–160Google Scholar
  370. Jones SE, Goddon J (eds) (1977) Proceedings of the Conference on non-Hodgkin’s Lymphomas. September 30 to October 2, 1976, San Francisco, California. Cancer Treatm Rep 61: 935–1227Google Scholar
  371. Jones SE, Rosenberg SA, Kaplan HS (1972) Non-Hodgkin’s lymphomas. I. Bone marrow involvement. Cancer (Philad) 29: 945–960Google Scholar
  372. Jones SE, Fuks ZM, Bull M, Kadin ME, Dorfman RF, Kaplan HS, Rosenberg SA, Kim H (1973) Non-Hodgkin’s lymphomas. IV. Clinicopathologic correlation in 405 cases. Cancer 31: 806–823PubMedCrossRefGoogle Scholar
  373. Kadin ME (1983) The Reed-Sternberg cell: biological and clinical significance. In: Bennett JM (ed) Controversies in the management of lymphomas. Nijhoff, Boston, pp 55–90CrossRefGoogle Scholar
  374. Kadin ME, Stites DP, Levy R, Warnke R (1978) Exogenous immunoglobulin and the macrophage origin of Reed-Sternberg-cells in Hodgkin’s disease. N Engl J Med 299: 1208–1214PubMedCrossRefGoogle Scholar
  375. Kahler O (1889) Zur Symptomatologie des multiplen Myeloms. Beobachtung von Albumosurie. Prag Med Wschr 14: 45–49Google Scholar
  376. Kajita A, Hirokawa K (1973) An autopsy case of aleukemic megakaryocytosis. Acta Path Jpn 23: 421Google Scholar
  377. Kaplan HS (1962) The radical radiotherapy of regionally localized Hodgkin’s disease. Radiol 78: 533–561Google Scholar
  378. Kaplan HS (1965) Radiotherapeutic management of the malignant lymphomas. Med Rec Ann 58: 43–46Google Scholar
  379. Kaplan HS (1966) Evidence for a tumoricidal dose level in the radiotherapy of Hodgkin’s disease. Cancer Res 26: 1221–1224PubMedGoogle Scholar
  380. Kaplan HS (1968) Prognostic significance of the relapse free intervall after radiotherapy in Hodgkin’s disease. Cancer (Philad) 22: 1131–1136CrossRefGoogle Scholar
  381. Kaplan HS (1970) On the natural history, treatment and prognosis of Hodgkin’s disease. The Harvey lectures, Series 64:215–259. Academic Press, New YorkGoogle Scholar
  382. Kaplan HS (1972) Hodgkin’s disease, 2nd ed. Harvard University Press, Cambridge MA 1980 Kaplan HS (1980) Hodgkin’s disease: unfolding concepts concerning its nature, management and prognosis. Cancer 45:2439–2474Google Scholar
  383. Kaplan HS (1981) Hodgkin’s disease: Biology, treatment, prognosis. Blood 57: 813PubMedGoogle Scholar
  384. Kaplan HS, Bagshaw MA (1968) Radiation hepatits: possible preventation by combined isotopic and external therapy. Radiol 91: 1214–1220Google Scholar
  385. Kaplan HS, Gartner S (1977) „Sternberg-Reed“ giant cells of Hodgkin’s disease: cultivation in vitro, hetero transplantation and characterization as neoplastic macrophages. Int J Cancer 19: 511–525Google Scholar
  386. Kaplan HS, Rosenberg SA ( 1966 a) La radiothérapie segmentaire de la maladie de Hodgkin. Pre- mier results de deux essais thérapeutique controlés. Nouv rev franç hématol 6: 121–133Google Scholar
  387. Kaplan HS, Rosenberg SA (1966 b) Extended-field radiotherapy in advanced Hodgkin’s disease: Short-term results of 2 randomized clinical trials. Cancer Res 26: 1268–1276Google Scholar
  388. Kaplan HS, Dorfman RF, Nelsen TS, Rosenberg SA (1973) Staging laparotomy and splenectomy in Hodgkin’s disease: analysis of indications and patterns of involvement in 285 consecutive unselected patients. Natl Cancer Inst Monogr 36: 291–301PubMedGoogle Scholar
  389. Kaplan HS, Dorfman RF, Nelsen TS, Rosenberg SA (1974) Staging laparotomy and splenectomy in Hodgkin’s disease. Analysis of indication and patterns of involvement in 285 consecutive unselected cases. In: Musshoff K (ed) Recent results in cancer research, vol 46. Springer, Berlin Heidelberg New York, pp 118–122Google Scholar
  390. Kay NE, Howe RB, Douglas SD (1982) Effect of therapy on T cell subpopulation in patients with chronic lymphocytic leukemia. Leuk Res 6: 345–348PubMedCrossRefGoogle Scholar
  391. Kay NE, Johnson JD, Stanek R, Douglas SD (1977) T cell subpopulation in chronic lymphocytic leukemia: abnormalities in distribution and in vitro maturation. Blood 54: 540–544Google Scholar
  392. Keane TJ, Van Dyk J, Rider WD (1981) Idiopathic interstitial pneumonia following marrow transplantation: The relationship with total body irradiation. Int J Radiat Oncol Biol Phys 7: 1365–1370Google Scholar
  393. Keller AR, Kaplan HS, Lukes RJ, Rappaport H (1968) Correlation of histopathology with other prognostic indicators in Hodgkin’s disease. Cancer (Philad) 22: 487–499CrossRefGoogle Scholar
  394. Kemp IW, Stein GJ, Heasman MA (1980) Myeloid leukemia in Scotland. Lancet 1: 732–733CrossRefGoogle Scholar
  395. Khan FM, Williamson JF, Sewchand W, Kim TH (1980) Basic data for dosage calculation and compensation. Int J Radiat Oncol Biol Phys 6: 745–751PubMedCrossRefGoogle Scholar
  396. Kim TH, Khan FM, Galvin JM (1980) A report of the work party: Comparison of total body irradiation techniques for bone marrow transplantation. Int J Radiat Oncol Biol Phys 6: 779784Google Scholar
  397. Kim TH, Rybka WB, Lehnert S, Podgorsak EB, Freeman CR (1985) Interstitial pneumonitis following total body irradiation for bone marrow transplantation using two different dose rates. Int J Radiat Oncol Biol Phys 11: 1285–1291PubMedCrossRefGoogle Scholar
  398. Kleihauer E (1978) Hämatologie. Springer, Berlin Heidelberg New York, S 338–356CrossRefGoogle Scholar
  399. Klein HO, Mathe G, Hayat M (1977) Treatment by radiophosphorus versus busulfan in polycythaemia vera. Rec Res Cancer Res 62: 104Google Scholar
  400. Klein U, Reindl (1981) Abdominal lymph node alteration in diseases of the lympho-reticular system. In: Weissleder H, Bartos V, Clodius L, Mâlek P (eds) Progress in lymphology, Proc. VIIth Int Congr Lymphology, Florence 1979. Avicenum, pp 330–332Google Scholar
  401. Koehler PR (1978) Lymphography vs CT of lymphomas (Letter to the editor). AJR 131:1116 König E, Meusers P, Brittinger G (1979) Efficacy of doxorubicin in prolymphocytic leukaemia. Br J Haemat 42: 487–488Google Scholar
  402. Koppenfels RV (1971) Klinische Erfahrungen im Plasmozytom unter besonderer Berücksichtigung der Röntgendiagnostik und Strahlentherapie. Strahlenther 142: 276–285Google Scholar
  403. Korst DR, Clatanoff DV, Schilling RF (1956) On myelofibrosis. Arch Intern Med 97: 169CrossRefGoogle Scholar
  404. Kortmann C, Burrichter H, Monner D, Jahn G et al. (1984) Interleukin-1-like activity consitutively generated by Hodgkin derived cell lines. I Measurement in a human lymphocyte Costimulator assay. Immunobiol 166: 318–333Google Scholar
  405. Kritorian JG, Burke JS, Rosenberg SA, Kaplan HS (1979) Occurrence of non-Hodgkin’s lymphoma after therapy for Hodgkin’s disease. N Engl J Med 300: 452–458CrossRefGoogle Scholar
  406. Krüger GFR (1983/1984) „New Working Formulation“ für Non-Hodgkin-Lymphome: Eine klinisch-pathologische Korrelation. In: Diehl V, Sack H (Hrsg) Aktuelle Onkologie 12. Diagnostik und Therapie der Non-Hodgkin-Lymphome. Zuckschwerdt, München Bern Wien, pp 9–16Google Scholar
  407. Krüger GRF, Grisar T, Lennert K, Schwarze EW, Brittinger G (Kiel Lymphoma Study Group) Histopathological correlation of the Kiel with the original Rappaport classification of malignant non-Hodgkin’s lymphomas. Blut 43: 167–181Google Scholar
  408. Kubagawa H, Vogler LB, Capra JD, Conrad ME, Lawton AR, Cooper MD (1979) Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B cell differentiation. J Exp Med 150: 792–807Google Scholar
  409. Kubik S (1974) The anatomy of the lymphatic system. In: Musshoff K (ed) Recent results in cancer research, vol 46. Springer, Berlin Heidelberg New York, pp 233–239Google Scholar
  410. Kundrat H (1893) Über Lympho-Sarkomatosis. Wien Klin Wschr 6: 211, 234–239Google Scholar
  411. Kundrat H (1893) Über Lympho-Sarkomatosis. Wien Klin Wschr 6: 211, 234–239Google Scholar
  412. Kvaloy S, Godal T, Marton PF, Steen H, Brennhovd IO, Abrahamsen AF (1981) Spontaneous (3H)-thymidine uptake in histological subgroups of human B-cell lymphomas. Scand J Haematol 26: 221–234PubMedCrossRefGoogle Scholar
  413. Kwan DK, Norman A (1977) Radiosensitivity of human lymphocyte and thymocytes. Radiat Res 69: 143–151PubMedCrossRefGoogle Scholar
  414. Lackner K, Brecht G, Janson R, Scherholz K, Lützeler A, Thurn P (1980) Wertigkeit der Computertomographie bei der Stadieneinteilung primärer Lymphknotenneoplasien. Fortschr Röntgenstr 132: 21–30CrossRefGoogle Scholar
  415. Laeger KKR (1977) Entstehung und Ausbreitung der Hodgkin’schen Erkrankung nach Strahlentherapie. Inaugural Dissertation, Freiburg im Br.Google Scholar
  416. Lam WV, Lindskoug BA, Order SE, Grant DG (1979) The dosimetry of 60-Co total body irradiation. Int J Radiat Oncol Biol Phys 5: 905–911PubMedGoogle Scholar
  417. Lamberg SJ, Bunn PA Jr (eds) (1979) Proceedings of the workshop on cutaneous T cell lymphomas (mycosis fungoides and Sézary syndroms). Cancer Treatm Rep 63: 561Google Scholar
  418. Lamberg SJ, Green SB, Byar DP, Block JB, Clendenning WE, Douglas MC, Epstein EH Jr, Fuks ZY, Golitz LE, Lorincz AL, McBurney EI, Michel B, Roenigk HH Jr, van Scott EJ, Vonderheid EC (1984) Clinical staging for cutaneous T-cell lymphoma. Ann Intern Med 100: 187–192PubMedGoogle Scholar
  419. Lampert F (1977) Kombinations-Chemotherapie und Hirnschädelbestrahlung bei 530 Kindern mit akuter lymphoblastischer Leukämie. Dtsch Med Wschr 102: 917PubMedCrossRefGoogle Scholar
  420. Lampert F, Henze G, Langermann HJ, Schellong G, Gadner H, Riehm HJ (1984) Acute lymphoblastic leukemia: Current status of therapy in children. Rec Res Cancer Res 93: 159–181Google Scholar
  421. Landbeck G, Winkler K (1977) Die Klinik der malignen Non-Hodgkin-Lymphome im Kindesalter. Verh Dtsch Ges Path 61: 404Google Scholar
  422. Landbeck G, Winkler K (1979) Maligne Non-Hodgkin-Lymphome im Kindesalter. In: Stacher A, Höcker P (Hrsg) Lymphknotentumoren, Pathophysiologie, Klinik und Therapie. Urban & Schwarzenberg, München, S 234–239Google Scholar
  423. Landbeck G, Gaedicke G, Winkler K, Stein H (1976) Besonderheiten der malignen Lymphome im Kindesalter. In: Löffler H (ed) Maligne Lymphome und monoklonale Gammopathien, Bd XVIII: Hämatologie und Bluttransfusion. Lehmann, München, S 225–235Google Scholar
  424. Landberg T (1974) Radiosensitivity problems in mantle treatment of Hodgkin’s disease. In: Lopez GJ, Monmati J, Berry RH, Hopewell JW (eds) Proc. XIII. Intern Congress of Radiology, Madrid, October 15–20, 1973. Radiol 2: 115–116. Excerpta Medica, AmsterdamGoogle Scholar
  425. Landberg T, Forslo H (1970) Radiosensitivity of mediastinal lymphomas in Hodgkin’s disease treated with split-course radiotherapy. Acta Radiol Ther Phys Biol 9: 177–189PubMedGoogle Scholar
  426. Landberg T, Larsson LE (1969) Hodgkin’s disease. Retrospective clinicopathologic study in 149 patients. Acta Radiol (Stockh) 8: 390–414Google Scholar
  427. Lang W, Kienzle S, Diehl V (1980) Proliferation kinetics of malignant non-Hodgkin’s lymphomas related to histopathology of lymph node biopsies. Virchows Arch A Path Anat Histol 389: 397–407CrossRefGoogle Scholar
  428. Langermann HJ, Henze G, Wulf M, Riehm HJ (1982) Abschätzung der Tumorzellmasse bei der akuten lymphoblastischen Leukämie im Kindesalter: prognostische Bedeutung und praktische Anwendung. Klin Pädiat 194: 209–213CrossRefGoogle Scholar
  429. Laurence J, Coleman M, Allen SL, Silver RT, Pasmantier M (1982) Combination chemotherapy of advanced diffuse histiocytic lymphoma with the six-drug COP-BLAM regimen. Ann Intern Med 97: 190–197PubMedGoogle Scholar
  430. Lauwers L, Dancot H (1966) Rélation entre le degré d’activité de la maladie de Hodgkin au cours des cinq premières années et le devenir des malades survivant a cinq ans. Nouv rev franç hématol 6: 98–101Google Scholar
  431. Law IP, Blom J (1977) Adult acute leukemia: Frequency of central nervous system involvement in long term survivors. Cancer 40: 1304–1306Google Scholar
  432. Lawrence JH (1955) Polycythaemia, physiology, diagnosis and treatment based on 303 cases. Grune & Stratton, New YorkGoogle Scholar
  433. Lee CK, Bloomfield CD, Goldman AI et al. (1980) Prognostic significance of mediastinal in- volvement in Hodgkin’s disease treated with curative radiotherapy. Cancer 46: 2403–2409PubMedCrossRefGoogle Scholar
  434. Lee LA, Fritz KA, Golitz L, Fritz TJ, Weston WL (1982) Second cutaneous malignancies in patients with mycosis fungoides treated with topical nitrogen mustard. J Am Acad Dermatol 7: 590–598PubMedCrossRefGoogle Scholar
  435. Lehnert S (1985) Response of the lung to intermittent irradiation: the importance of average versus instantaneous dose rate. Int J Radiat Oncol Biol Phys 11: 2183–2184PubMedCrossRefGoogle Scholar
  436. Leibfried H, Kerssenfischer V, Fiss N, Werner S (1975) Prognost. Untersuchung. Medizin Technik, BaselGoogle Scholar
  437. Lennert K (1967) Classification of malignant lymphomas (European Concept). In: Rüttimann A (ed) Progress in lymphology. Thieme, Stuttgart, pp 103–109Google Scholar
  438. Lennert K (1973) Pathologisch-histologische Klassifizierung der malignen Lymphome, Pathophysiologie, Klinik, Chemo-und Immuntherapie. In: Stacher A (Hrsg): Leukämien und maligne Lymphome. Urban & Schwarzenberg, München Berlin Wien, S 181–194Google Scholar
  439. Lennert K (1976) Klassifikation und Morphologie der Non-Hodgkin-Lymphome. In: Löffler H (Hrsg) Maligne Lymphome und monoklonale Gammopathien. Hämatologie und Bluttransfusion, Bd 18. Lehmann, München, S 145–150Google Scholar
  440. Lennert K (1977) Klassifikation der Non-Hodgkin-Lymphome im Kindesalter. Klin Pädiat 189/ 1: 7Google Scholar
  441. Lennert K (1984) Zur Kiel-Klassifikation der malignen Lymphome. In: Diehl V, Sack H (Hrsg) Aktuelle Onkologie 12. Diagnostik und Therapie der Non-Hodgkin-Lymphome. Zuckschwerdt, München Bern Wien, S 3–8Google Scholar
  442. Lennert K (1985) Lymphoproliferative Erkrankungen. In: Gross R, Schmidt CG (Hrsg) Klinische Onkologie. Thieme, Stuttgart New York, S 13. 20–34Google Scholar
  443. Lennert K, Collins RD, Lukes RJ (1983) Concordance of the Kiel and Lukes-Collins classification of non-Hodgkin’s lymphomas. Histopathol 7: 549–559CrossRefGoogle Scholar
  444. Lennert K, Mohri N (1974) Histologische Klassifizierung und Vorkommen des M. Hodgkin. Internist 15: 57–65Google Scholar
  445. Lennert K, Stein H (1981) Histopathologie der Non-Hodgkin-Lymphome (nach der Kiel-Klassifikation). Springer, Berlin Heidelberg New YorkGoogle Scholar
  446. Lennert K, Stein H, Kaiserling E (1975 a) Cytological and functional criteria for the classification of malignant lymphoma. Brit J Cancer 31, Suppl II, pp 29–43Google Scholar
  447. Lennert K, Mohri N, Stein H, Kaiserling E ( 1975 b) The histopathology of malignant lymphoma. Br J Haemat, Suppl 31: 193–203Google Scholar
  448. Lennert K, Mohri N, Stein H, Kaiserling E, Müller-Hermelink HK (1978) Malignant lymphomas other than Hodgkin’s disease: histology, cytology, ultrastructure, immunology. In: Uehlinger E (eds) Handbuch der speziellen pathologischen Anatomie und Histologie, Bd I/ 3B. Springer, Berlin Heidelberg New YorkGoogle Scholar
  449. Lennert K, Kikuchi M, Sato E, Suchi T, Stansfeld AG, Feller AC, Hansmann M-L, Müller-Hermelink HK, Gödde-Salz E (1985) HTLV-positive und -negative T-cell-lymphomas. Morphological and immunohistochemical differences between European and HTLV-positive Japanese T-cell lymphomas. Int J Cancer 35: 65–72Google Scholar
  450. Leonard RCF, Cuzick J, MacLennan ICM, Vanhegan RI, Mackie PH, McCormick CV, and the Oxford Lymphoma Group (1983) Prognostic factors in non-Hodgkin’s lymphoma: the importance of symptomatic stage as an adjunct to the Kiel histopathological classification. Br J Cancer 47: 91–102CrossRefGoogle Scholar
  451. Leonard RCF, Cuzick J, MacLennan ICM, Vanhegan RI, Mackie PH, McCormick CV, and the Oxford Lymphoma Group (1983) Prognostic factors in non-Hodgkin’s lymphoma: the importance of symptomatic stage as an adjunct to the Kiel histopathological classification. Br J Cancer 47: 91–102CrossRefGoogle Scholar
  452. Lesser M, Chang JC, Yoo OH, Roswit B (1983) Bronchioalveolar carcinoma arising in areas previously irradiated for Hodgkin’s disease. South Med J 76: 689–691PubMedCrossRefGoogle Scholar
  453. Levi JA, Wiernik PH (1975) Management of mycosis fungoides: current status and future prospects. Medicine 54: 73–88PubMedCrossRefGoogle Scholar
  454. Levi JA, Wiernik PH ( 1977 a) Limited extranodal Hodgkin’s disease. Unfavourable prognosis and therapeutic implications. Am J Med 63: 365–372Google Scholar
  455. Levi JA, Wiernik PH (1977 b) The therapeutic implications of splenic involvement in stage IIIA Hodgkin’s disease. Cancer 39: 2158–2165Google Scholar
  456. Levi JA, Peter H, Wiernik PH, O’Connell J (1977) Patterns of relapse in stages I, II and IIIA Hodgkin’s disease: influence of initial therapy and implications for the future. Int J Radiat Oncol Biol Phys 2: 853–862PubMedCrossRefGoogle Scholar
  457. Levine AM (1980) Clinical manifestations of T-cell lymphomas. In: van den Tweel JG, Taylor CR, Bosman FT (eds) Malignant lymphoproliferative diseases. Boerhaave series, vol XVII. Leiden University Press, Boston, pp 331–339Google Scholar
  458. Levine AM, Forman SJ, Meyer PR, Koehler SC, Liebman H, Paganini-Hill A, Pockros A, Lukes RJ, Feinstein DI (1983) Successful therapy of convoluted T-lymphoblastic lymphoma in the adult. Blood 61: 92–98PubMedGoogle Scholar
  459. Levitt SH, Lee CKK (1983) Radical radiation therapy in the treatment of laparotomy staged Hodgkin’s disease patients. In: Amendola BE, Amendola MA (eds) Recent trends in radiation oncology and related fields. Elsevier, Amsterdam, pp 21–38Google Scholar
  460. Levitt SH, Bloomfield CD, Frizzera G, Lee CKK (1980) Curative radiotherapy for localized diffuse histiocytic lymphoma. Cancer Treat Rep 64: 175–177PubMedGoogle Scholar
  461. Levitt SH, Lee CKK, Bloomfield CD, Frizzera (1985) The role of radiation therapy in the early treatment of early stage large cell lymphoma. Hematol Oncol 3: 33–37Google Scholar
  462. Levy R, Kaplan HS (1974) Impaired lymphocyte function in untreated Hodgkin’s disease. N Engl J Med 290: 181–186PubMedCrossRefGoogle Scholar
  463. Lewis EB (1963) Leukemia, multiple myeloma and aplastic anemia in American radiologists. Science 142: 1492–1494PubMedCrossRefGoogle Scholar
  464. Lewis SM, Szur L (1963) Malignant myelosclerosis. Br Med J I1: 472–477Google Scholar
  465. Lewitt SH, Bloomfield CD, Lee CKK, Nesbit ME, McKenna RW (1976) Extended field radiotherapy in non-Hodgkin’s lymphoma. Radiology 118: 457–459Google Scholar
  466. Li FP, Corkery J, Canellos G, Neitlich HW (1981) Breast cancer after Hodgkin’s disease in two sisters. Cancer 47: 200–202PubMedCrossRefGoogle Scholar
  467. Liew KH, Easton D, Horwich A, Barret A, Peckham MJ (1984) Bulky mediastinal Hodgkin’s disease management and prognosis. Hematol Oncol 2: 45–59PubMedGoogle Scholar
  468. Lindeboom GA (1938) Über die sog. aleukämische megakaryozytäre Myelose. Acta Med Scand 95: 388–414CrossRefGoogle Scholar
  469. Lindh J, Lenner P, Roos G (1984) Monoclonal B cells in peripheral blood in non-Hodgkin’s lymphoma. Correlation with clinical features and DNA content. Scand J Haemat 32: 5–11Google Scholar
  470. Lipshitz HI, Cohen MA (1982) Radiation induced osteochondromas. Radiology 142: 643–647Google Scholar
  471. Lipton A, Lee BJ (1971) Prognosis of stage I lymphosarcoma and reticulum cell sarcoma. N Engl J Med 284: 230–233PubMedCrossRefGoogle Scholar
  472. Lister TA, Malpas JS (1983) The lymphomas–current management. Postgrad Med J 59: 219–228PubMedCrossRefGoogle Scholar
  473. Longo DL, DeVita VT Jr, Glatstein E, Matis LA, Fisher RI, Young RC (1984) Watch and wait versus aggressive combined modality therapy for advanced favourable prognosis non-Hodgkin’s lymphomas. Second Intern. Conf. Malignant Lymphoma, Lugano, June 13–16, 1984Google Scholar
  474. Lopez-Cardozo B, Hagenbeek A (1985) Interstitial pneumonitis following bone marrow transplantation: pathogenesis and therapeutic considerations. Int J Cancer Clin Oncol 21: 48–51Google Scholar
  475. Lukes RJ (1972) The pathological manifestations of Hodgkin’s disease. Z Krebsforsch 78: 129–136CrossRefGoogle Scholar
  476. Lukes RJ, Butler JJ (1966) The pathology and nomenclature of Hodgkin’s disease. Cancer Res 26: 1063–1081PubMedGoogle Scholar
  477. Lukes RJ, Collins RD ( 1974 a) Functional approach to the classification of malignant lymphoma. In: Musshoff K (ed) Recent results in cancer research, vol 46. Springer, Berlin Heidelberg New York, pp 19–30Google Scholar
  478. Lukes RJ, Collins RD (1974 b) Immunologic characterisation of human malignant lymphomas. Cancer 34 (Suppl):1488–1503Google Scholar
  479. Lukes RJ, Taylor CR, Parker JW (1982) Immunological surface marker studies in the histopathological diagnosis of non-Hodgkin’s lymphomas based on multiparameter studies of 790 cases. In: Rosenberg SA, Kaplan HS (eds) Malignant lymphomas: etiology, immunology, pathology, treatment. Academic Press, New York, pp 309–350Google Scholar
  480. Lukes RJ, Tindle BH, Parker JW (1969) Reed-Sternberg like cells in infectious mononucleosis. Lancet 11: 1003–1004CrossRefGoogle Scholar
  481. Lukes RJ, Craver LF, Hall TC, Rappaport H, Rubin P (1966) Report of the nomenclature cornittee. Cancer Res 26: 1311Google Scholar
  482. Lutzner M, Edelson R, Schein P, Green I, Kirkpatrick C, Ahmed A (1975) Cutaneous T-cell lymphomas: the Sézary syndrome, mycosis fungoides, and related disorders. Ann Intern Med 83: 534–552PubMedGoogle Scholar
  483. Mackintosh FR, Colby TV, Podolsky WJ, Burke JS, Hoppe RT, Rosenfelt FP, Rosenberg SA, Kaplan HS (1982) Central nervous system involvement in non-Hodgkin’s lymphoma: An analysis of 105 cases. Cancer (Philad) 49: 586–595CrossRefGoogle Scholar
  484. MacMahon B (1957) Epidemiological evidence on the nature of Hodgkin’s disease. Cancer (Philad) 10: 1045–1054CrossRefGoogle Scholar
  485. MacMahon B (1966) Epidemiology of Hodgkin’s disease. Cancer Res 26: 1189–2000PubMedGoogle Scholar
  486. Magrath IT (1984) Burkitt’s lymphoma: clinical aspects and treatment. In: Molander DW (ed) Disease of the lymphatic system. Diagnosis and therapy. Springer, Berlin Heidelberg New York, pp 103–139CrossRefGoogle Scholar
  487. Magrath IT, Janus C, Edwards BK, Spiegel R, Jaffe ES, Berard CW, Miliauskas J, Morris K, Barnwell R (1984) An effective therapy for both undifferentiated (including Burkitt’s) lymphomas and lymphoblastic lymphomas in children and young adults. Blood 63: 1102–1111PubMedGoogle Scholar
  488. Manohaven A, Schonell M (1980) Radiation pneumonia complicating adjuvant cytotoxic chemotherapy. Austr NZ J Med 10: 218–220CrossRefGoogle Scholar
  489. Marinello G, Marrie AM, le Bourgois JP (1982) Measurement and calculation of lung dose in total body irradiations performed with cobalt-60. J Eur Radiother 3: 174–182Google Scholar
  490. Markowitz MH, Mouradian JA, Moore A (1984) Acute and chronic lymphocytic leukemia. In: Molander DW (ed) Diseases of the lymphatic system. Diagnosis and therapy. Springer, Berlin Heidelberg New York, pp 51–70CrossRefGoogle Scholar
  491. Marx JL (1985) More progress on the HTLV-family. Science 227: 156–157PubMedCrossRefGoogle Scholar
  492. Mary-Rabine L, Waleffe A, Kulbertus HE (1980) Severe conduction disturbances and ventrikular arrhythmias complicating mediastinal irradiation for Hodgkin’s disease: a case report. PACE 3: 612–617PubMedCrossRefGoogle Scholar
  493. Mason DY (1982) The paraproteinaemias. In: Hardisty RM, Weatherall DJ (eds) Blood and its disorders, 2nd ed. Blackwell, Oxford, pp 701–750Google Scholar
  494. Mathé G, Rappaport H, O’Conor GT, Torloni H (1976) Histological and cytological typing of neoplastic diseases of haematopoietic and lymphoid tissues. Intern Histological Classification of Tumors, No. 14. World Health Organization, GenevaGoogle Scholar
  495. Mauch P, Goodman R, Hellman S (1978) The significance of mediastinal involvement in early stage Hodgkin’s disease. Cancer 42: 1039–1045PubMedCrossRefGoogle Scholar
  496. Mauch P, Gorshein D, Cunningham J, Hellman S (1982) Influence of mediastinal adenopathy on site and frequency of relapse in patients with Hodgkin’s disease. Cancer Treatm Rep 66: 809–817Google Scholar
  497. McElwain TJ, Wrigley PFM, Hunter A et al. (1973) Combination chemotherapy in advanced and recurrent Hodgkin’s disease. Natl Cancer Inst Monogr 36: 495–502Google Scholar
  498. McKelvey EM, Moon TE (1977) Curability of non-Hodgkin’s lymphomas. Cancer Treatm Rep 61: 1185–1190Google Scholar
  499. Medical Research Council’s Working Party for Therapeutic Trials in Leukemia (1968) Chronic granulocytic leukaemia: Comparison of radiotherapy and busulfan therapy. Br Med J 1:2O1–208Google Scholar
  500. Meeting of Paris 1978 (1979) Symposium on total body irradiation for bone marrow transplantation. Pathol Biol 27: 317–380Google Scholar
  501. Meijer CJLM, van der Loo EM, van Vloten WA, van der Velde EA, Scheffler E, Cornelisse CJ (1980) Early diagnosis of mycosis fungoides and Sézary syndrome by morphometric analysis of lymphoid cells in the skin. Cancer 45: 2864–2871PubMedCrossRefGoogle Scholar
  502. Mellstedt H, Killander D, Pettersson D (1977) Bone marrow kinetic studies on three patients with myelomatosis. Indications for malignant proliferation within both the plasma cell and lymphoid cell compartments. Acta Med Scand 202: 413–417Google Scholar
  503. Meugé G, Hoerni B, DeMascarel A, Durand M, Richaud P, Hoerni-Simon G, Chauvergne J, Lagarde C (1978) Non-Hodgkin malignant lymphomas. Clinico-pathologic correlations with the Kiel classification. Eur J Cancer 14: 587–592Google Scholar
  504. Meuret G, Hoffmann G, Gmelin R (1975) Erfahrungen mit der Radiophosphor-Therapie bei Polycythaemia vera. Strahlenther 149: 49–54Google Scholar
  505. Meuret G, Fliedner TM, Schütz W, Ohl N, Afkham J, Obrecht P, Musshoff K (1971) Erfahrungen mit der extrakorporalen Blutbestrahlung bei der Behandlung der chronisch-lymphatischen Leukämie. KIM Wschr 49: 899–904CrossRefGoogle Scholar
  506. Meuret G, Schütz W, Afkham J, Fliedner TM, Obrecht P, Musshoff K (1969) Langzeittherapie der chronisch-lymphotischen Leukämie durch extrakorporale Blutbestrahlung. In: Stacher A (Hrsg) Chemo-und Immuntherapie der Leukosen und malignen Lymphome. Bohmann, Wien, S 247–251Google Scholar
  507. Meuret G, Schütz W, Harris EB, Fliedner TM, Hoelzer D, Afkham J, Obrecht P, Musshoff K, Heinze V, Tourkantonis A (1969) Die Behandlung der chronisch-lymphatischen Leukämie durch extrakorporale Blutbestrahlung unter Verwendung konventioneller Strahlentherapiegeräte. Strahlenther 137: 429–441Google Scholar
  508. Meusers P, König E, Brittinger G (1981) Clinical aspects of non-cutaneous T-lymphomas. Path Res Pract 171: 216–239PubMedCrossRefGoogle Scholar
  509. Meusers P, Bartels H, Brittinger G, Common H, Dühmke E, Fülle HH, Gunzer U, Heinz R, König E, Musshoff K, Pralle H, Schmalhorst U, Theml H, Krüger GRF, Lennert K (Kiel Lymphoma Study Group) (1979) Heterogeneity of diffuse “histiocytic” lymphoma according to the Kiel classification. N Engl J Med 301: 384Google Scholar
  510. Meusers P, Bartels H, Binder T, Common H, Dühmke E, Engelhardt M, Fülle HH, Günzer U, Gyenes T, Havemann K, Heinz R, König E, König HJ, Kuse R, Löffler H, Ludwig WD, Pezzutto A, Pralle H, Schoppe WD, Thernl H, Zurborn KH, Zwingers T, Lennert K, Brittinger G (Kiel Lymphoma Study Group) (1985) Centrocytic lymphoma: clinical features and therapeutic aspects of a non-Hodgkin-lymphoma of intermediate-grade prognosis. Intern. Symp. Recent Approaches to chronic Lymphoproliferative diseases, Prag 4.-6. September, Abstract 83Google Scholar
  511. Meyler TS, Blumberg AL, Purser P (1978) Total skin electron beam therapy in mycosis fungoides. Cancer 42: 1171–1176PubMedCrossRefGoogle Scholar
  512. Micaily B, Vonderheid EC, Brady LW (1983) Combined moderate dose electron beam radiotherapy and topical chemotherapy for cutaneous T-cell lymphoma. Int J Radiat Oncol Biol Phys 9: 475–479PubMedCrossRefGoogle Scholar
  513. Mijnheer RI (1982) Summary of the discussion on delivery of dose to the patient (including beam monitoring). J Eur Radiother 3: 257–258Google Scholar
  514. Mill WB, Griffith R (1980) The role of radiation therapy in the management of plasma cell tumors. Cancer 45: 647–652PubMedCrossRefGoogle Scholar
  515. Miller DD, Waters DD, Dangoisse V, David PR (1983) Symptomatic coronary artery spasm following radiotherapy for Hodgkin’s disease. Chest 83: 284–285PubMedCrossRefGoogle Scholar
  516. Miller TP, Jones SE (1983) Initial chemotherapy for clinical localized lymphomas of unfavourable histologies, stages I and II. Cancer 52: 2300–2307CrossRefGoogle Scholar
  517. Minna JD, Roenigk HH Jr, Glatstein E (1979) Report of the committee on therapy for mycosis fungoides and Sézary syndrome. Cancer Treatm Rep 63: 729–736Google Scholar
  518. Modan B (1971) The polycythaemic disorders. Thomas, Springfield IllGoogle Scholar
  519. Molls M, Budach V, Bamberg M (1986) Total body irradiation: the lung as critical organ. Strahlenther 162: 226–232Google Scholar
  520. Molls M, van Beuningen D (1985) Strahlenbiologische Veränderungen der Lunge. In: Diethelm L, Heuck F, Olsson O, Strnad F (eds) Handbuch der medizinischen Radiologie, Bd XX. Heuck F, Scherer E (red) Strahlengefährdung und Strahlenschutz. Springer, Berlin Heidelberg New York, S 380–402Google Scholar
  521. Monfardini S, Banfi A, Bonadonna G, Rilke F, Milani F, Valagussa P, Lattuada A (1980) Improved five year survival after combined radiotherapy for stage I-II non-Hodgkin’s lymphoma. Int J Radiat Oncol Biol Phys 6: 125–134PubMedCrossRefGoogle Scholar
  522. Moore MR, Jones SE, Bull JM, William LA, Rosenberg SA (1973) MOPP chemotherapy for advanced Hodgkin’s disease–prognostic factors in 81 patients. Cancer 32: 52–60PubMedCrossRefGoogle Scholar
  523. Moretta H, Webb SR, Grossi CE, Lydyard PM, Cooper MD (1977) Functional analysis of two human T-cell subpopulations. Help and suppression of B cell responses by T cells bearing receptors for IgM or IgG. Exp Med 146: 184–200Google Scholar
  524. Moretta L, Mingari MC, Moretta H, Cooper MS (1979) Human T lymphocytes subpopulations: studies on the mechanisms by which T cells bearing Fe receptors for IgG suppress T dependent B cell differentiation induced for pockweed mitogen. J Immunol 122: 984–990PubMedGoogle Scholar
  525. Morris LL, Cassady JR, Jaffe N (1975) Sternal changes following irradiation for childhood Hodgkin’s disease. Radiology 115: 701–705PubMedGoogle Scholar
  526. Moss WT, Brand WN, Battifora H (1973) Radiation oncology. Rationale, technique, results, 4th ed. Mosby, St. LouisGoogle Scholar
  527. Müller-Weihrich S, Henze G, Jobke A, Kornhuber B, Langermann HJ, Lasson U, Ludwig R, Ritter J, Schellong G, Stollmann B, Treuner J, Riehm H (1982) BFM-Studie 1975/1981 zur Behandlung der Non-Hodgkin-Lymphome hoher Malignität bei Kindern und Jugendlichen. Klin Pädiat 194: 219–225CrossRefGoogle Scholar
  528. Müller-Weihrich S, Henze G, Langermann HJ, Riehm H (1983) Therapieergebnisse bei NonHodgkin-Lymphomen im Kindesalter; Therapiestrategie in Abhängigkeit vom zytologischimmunologischen Typ und Ausbreitungsstadium. Verh Dtsch Krebs-Ges 4: 217Google Scholar
  529. Müller-Weihrich S, Beck J, Henze G, Jobke A, Kornhuber B, Lampert F, Ludwig R, Prindull G, Schellong G, Spaar HJ, Stollmann B, Treuner J, Wahlen W, Weinel P, Riehm H (1984) BFM-Studie 1981/1983 zur Behandlung hochmaligner Non-Hodgkin-Lymphome bei Kindern: Ergebnisse einer nach histologisch-immunologischem Typ und Ausbreitungsstadium stratifizierten Therapie. Klin Pädiatr 196: 135–142Google Scholar
  530. Murphy SB (1976) Non-Hodgkin’s lymphomas of childhood. In: Donaldson M, Sendel HG (eds) Trends in childhood cancer. Wiley, New York, pp 31Google Scholar
  531. Murphy SB (1977) Management of childhood non-Hodgkin’s lymphoma. Cancer Treatm Rep 61: 1161–1173Google Scholar
  532. Murphy SB (1980) Classification, staging and end results of treatment of childhood non-Hodgkin’s lymphomas: Dissimilarities from lymphomas in adults. Semin Oncol 7: 332–339PubMedGoogle Scholar
  533. Musshoff K (1969) Der heutige Stand der Lymphogranulomatosebehandlung. Röntgenblätter 22: 1–19Google Scholar
  534. Musshoff K (1970) Therapy and prognosis of two different forms of organ involvement in cases of malignant lymphoma (Hodgkin’s disease, reticulum cell sarcoma, lymphosarcoma) as well as a report about stage division in these diseases. Klin Wschr 48: 673–676PubMedCrossRefGoogle Scholar
  535. Musshoff K (1971) Prognostic and therapeutic implications of staging in extranodal Hodgkin’s disease. Cancer Res 31: 1814–1827PubMedGoogle Scholar
  536. Musshoff K (1972) Grundlagen der Strahlentherapie des Morbus Hodgkin, Indikation und Ergebnisse. Z Krebsforsch 78: 162–191CrossRefGoogle Scholar
  537. Musshoff K (1973) Survival and relapse data in Hodgkin’s disease: Freiburg im Breisgau, 19481969. Natl Cancer Inst Monogr 36: 531–539PubMedGoogle Scholar
  538. Musshoff K (1974) Maligne Lymphome. Ärztliche Praxis 24:1130–1134, 25: 1198–1202Google Scholar
  539. Musshoff K (1975/1976) Die Strahlenbehandlung der Hodgkinschen Erkrankung In: H. Löffler (Hrsg) Maligne Lymphome und monoklonale Gammopathien. Blut, Sonderbd 18: 119–134Google Scholar
  540. Musshoff K (1975/1976) Die Strahlenbehandlung der Non-Hodgkin-Lymphome. In: Löffler H (Hrsg) Maligne Lymphome und monoklonale Gammopathien. Blut, Sonderbd 18: 315–328Google Scholar
  541. Musshoff K (1978) Voraussetzungen und Probleme der adjuvanten Chemotherapie in Verbindung mit der primären Strahlentherapie der Nicht-Hodgkin-Lymphome unter besonderer Berücksichtigung der Histologie. In: Huber H, Senn HJ, Falkensammer M (Hrsg) Adjuvante zytostatische Chemotherapie. Zytostatische Therapie als Rezidivprophylaxe? Hämatologie und Bluttransfusion, Bd XXII. Springer, Berlin Heidelberg New York, S 101–114Google Scholar
  542. Musshoff K (1979) On the problems and the tasks of the clinical non-Hodgkin lymphoma research today. Advances in Medical Oncology, Research and education. In: Crowther DG (ed), vol VII: leukemia and non-Hodgkin-lymphoma. Pergamon Press, Oxford New York Toronto Sidney Paris Frankfurt, pp 153–162Google Scholar
  543. Musshoff K (1979) Die Strahlentherapie der Non-Hodgkin-Lymphome (Indikation und Probleme) In: Stacher A, Höcker P (Hrsg) Lymphknotentumoren, Pathophysiologie, Klinik und Therapie. Urban & Schwarzenberg, München, S 157–165Google Scholar
  544. Musshoff K, Boutis L (1967) Die Frage der Heilbarkeit der Lymphogranulomatose, beurteilt nach den Behandlungsergebnissen der Freiburger Medizinischen Klinik. Verh Dtsch Ges Inn Med 73: 322–329PubMedGoogle Scholar
  545. Musshoff K, Boutis L ( 1969 b) Die Behandlungsergebnisse der malignen Lymphogranulomatose (M. Hodgkin) in Abhängigkeit von individuellen und krankheitsspezifischen Faktoren und der Therapie. Klin Wschr 47: 93–102Google Scholar
  546. Musshoff K, Boutis L ( 1969 a) Beurteilung, Behandlungsgrundsätze und -ergebnise bei der Lymphogranulomatose. Strahlenther, Sonderbd 69: 59–74Google Scholar
  547. Musshoff K, Brücher H (Kiel Lymphoma Study Group) (1981) Diagnostic and therapeutic problems in non-Hodgkin’s lymphomas. Blut 43: 143–154 (Übersicht)Google Scholar
  548. Musshoff K, Schmidt-Vollmer H (1975 a) Prognostic significance of primary site after radiotherapy in non-Hodgkin’s lymphomata. Br J Cancer, Suppl 11, 31: 425–434Google Scholar
  549. Musshoff K, Schmidt-Vollmer H (1975 b) Prognosis of Non-Hodgkin’s lymphomas with special emphasis on staging classification. Z Krebsforsch 83: 323–341Google Scholar
  550. Musshoff K, Schmidt-Vollmer H, Merten D (1971) Reticulum cell sarcoma, an oncologic model for a system of classifying the malignant lymphomas. Eur J Cancer 7: 451–457PubMedGoogle Scholar
  551. Musshoff K, Slanina J (1976, 1980 ) Maligne Systemerkrankungen. In: Scherer E (Hrsg) Strahlentherapie, Radiologische Onkologie. Springer, Berlin Heidelberg New York A. Aufl 1976:705–788, 2. Aufl 1980: 863–968Google Scholar
  552. Musshoff K, Stamm H, Lummel G, Gössel K (1964) Zur Prognose der Lymphogranulomatose. Klinisches Bild und Strahlentherapie. Freiburger Krankengut 1938–1958. Beiträge zur inneren Medizin. Schattauer, Stuttgart, S 549–561Google Scholar
  553. Musshoff K, Boutis L, Obrecht P, Karsch T (1968 a) Die Lebenserwartung bei der chronischen myeloischen Leukaemie in Abhängigkeit von der Therapie. Freiburger Ergebnisse 19451966. Verh Dtsch Ges Inn Med 74: 648–652Google Scholar
  554. Musshoff K, Renemann H, Boutis L, Afkham J ( 1968 b) Die extranoduläre Lymphogranulomatose: Diagnose, Therapie und Prognose bei zwei unterschiedlichen Formen des Organbefalls. Ein Beitrag zur Stadieneinteilung des Morbus Hodgkin. Fortschr Röntgenstr 104: 776–786Google Scholar
  555. Musshoff K, Renemann H, Boutis L, Afkham JA (1968/1970) The differentiation of two different types of stage IV Hodgkin’s disease. Intern Congress of Lymphology Miami, März 1968. In: Viamonte M, Koehler PR, Witte M, Witte Ch (eds) Progress in Lymphology II. Thieme, Stuttgart, pp 272–275Google Scholar
  556. Musshoff K, Boutis L, Obrecht P, Karsch T (1969) Die Lebenserwartung der chronischen myeloischen Leukaemie in Abhängigkeit von individuellen und krankheitsspezifischen Faktoren und der Therapie. Freiburger Ergebnisse 1947–1966. Klin Wschr 47: 179–183PubMedCrossRefGoogle Scholar
  557. Musshoff K, Hartmann C, Niklaus B, Rössner R ( 1974 a) Results of therapy in Hodgkin’s disease. Freiburg i. Br. 1964–1971. In: Musshoff K (ed) Recent results in cancer research, vol 46. Springer, Berlin Heidelberg New York, pp 206–220Google Scholar
  558. Musshoff K, Hartmann CHG, Niklaus B, Rössner R (1974 b) Prognostic value of the survival, remission, and recurrence rate of Hodgkin’s disease following radiation therapy. In: Lopez GH, Bonmati J, Berry RH, Hopewell JW (eds) Radiology. Proc. XIII. Intern. Congress of Radiology, Madrid, October 15–20; 1973. Excerpta Medica, Amsterdam; American Elsevier, New York, pp 7–10Google Scholar
  559. Musshoff K, Hartmann C, Niklaus B, Rössner R (1976) The prognostic significance of first and second remission in Hodgkin’s disease after first and second relapse radiotherapy. Z Krebsforsch 85: 243–270CrossRefGoogle Scholar
  560. Musshoff K, Schmidt-Vollmer H, Lennert K, Sandritter W (1976) Preliminary clinical findings on the Kiel classification of malignant lymphomas. Z Krebsforsch 87: 229–238CrossRefGoogle Scholar
  561. Musshoff K, Stotzingen v. W, Schmidt-Vollmer H, Umbach H (1981) Investigation results of a comparison made between the Kiel and Rappaport classifications of the non-Hodgkin’s lymphomas, together with clinical data. J Cancer Res Clin Oncol 100: 167–204PubMedCrossRefGoogle Scholar
  562. Musshoff K, Weidkuhn V, Bammert J, Felker HU ( 1985 a) Diagnostik und Therapie der Hodgkinschen Erkrankung in Freiburg im Breisgau 1964–1976. 1. Mitteilung: Ergebnisse des Gesamtkollektivs. Strahlenther 161: 581–595Google Scholar
  563. Musshoff K, Weidkuhn V, Bammert J, Felker HU (1985 b) Diagnostik und Therapie der Hodgkinschen Erkrankung in Freiburg im Breisgau 1964–1976. 2. Mitteilung: Ergebnisse der Behandlungsperiode 1971–1976 im Vergleich zur Periode 1964–1971. Strahlenther 161: 596–614Google Scholar
  564. Musumeci R, Damascelli B (1984) Radiologic approach to diseases of the lymph nodes. In: Molander DW (ed) Diseases of the lymphatic system. Diagnosis and therapy. Springer, Berlin Heidelberg New York, pp 245–268CrossRefGoogle Scholar
  565. Nathwani BN (1979) A critical analysis of the classifications of non-Hodgkin’s lymphomas. Cancer 44: 347–384PubMedCrossRefGoogle Scholar
  566. Nathwani BN, Kim H, Rappaport H (1976) Malignant lymphoma, lymphoblastic. Cancer 38: 964–983PubMedCrossRefGoogle Scholar
  567. Nathwani BN, Kim H, Rappaport H, Solomon J, Fox M (1978) Non-Hodgkin’s lymphomas. A clinicopathologic study comparing two classifications. Cancer 41: 303–325Google Scholar
  568. Neely SV, Golomb HM (1982) Tratment of stage IIIA Hodgkin’s disease. Cancer Treat Rep 66: 827–834PubMedGoogle Scholar
  569. Nelson HP (1934) The tracheo-bronchial lymphatic glands. J Anat (London) 66: 228Google Scholar
  570. Neumann CH, Robert NJ, Rosenthal D, Canellos G (1983) Clinical value of ultrasonography for the management of non-Hodgkin lymphoma patients as compared with abdominal computed tomography. J Comput Assist Tomogr 7: 666–669PubMedCrossRefGoogle Scholar
  571. Niemi KM (1979) PUVA treatment in mycosis fungoides. Dermatologica 158: 462–467PubMedCrossRefGoogle Scholar
  572. Nowak S, Caraveo J, Trowbridge AA, Peterson RF, White III RR (1979) Primary lymphomas of the gastrointestinal tract. Sth. Med J 72: 1154–1158Google Scholar
  573. Nowell PC, Finan JB (1978) Cytogenetics of acute and chronic myelofibrosis. Virchows Arch B 29: 45–50Google Scholar
  574. Obrecht JP (1982) Klinik der malignen Lymphome. In: Schwiegk H (Hrsg) Handbuch der inneren Medizin, Bd 1I/7. Springer, Berlin Heidelberg New York, pp 159–672Google Scholar
  575. O’Connor NTJ, Wainscoat JS, Stein H, Feller AC et al. Monoclonal T-cell proliferations in angioimmunoblastic lymphadenopathy. In: J Clin Pathol (im Druck)Google Scholar
  576. Ojeda VJ, Lee MA, Walters MNI, Vaughan RJ (1983) Primary malignant lymphomas of the brain. A clinicopathological study of five cases. Med J Aust 2: 146–150Google Scholar
  577. Olmer J, Gabriel B, Bove J (1967) Zur Behandlung der chronischen myeloischen Leukaemie. Dtsch RöntgenkongreB 1966, Teil B, S 276–277Google Scholar
  578. Orton CG, Herskovic A (1984) A proposal for uniform introduction of lung corrections. Int J Radiat Oncol Biol Phys 10: 2383–2384PubMedCrossRefGoogle Scholar
  579. Page V, Gardner A, Karzmark CJ (1970c) Patients dosimetry in electron treatment of large superficial lesions. Radiol 94: 635–641Google Scholar
  580. Page V, Gardner A, Karzmark CJ ( 1970 a) Physical and dosimetric aspects of the radiotherapy of malignant lymphomas. The mantle technique. Radiology 96: 609–618Google Scholar
  581. Page V, Gardner A, Karzmark C ( 1970 b) Physical and dosimetric aspects of the radiotherapy of malignant lymphomas. II. The inverted Y-technique. Radiology 96: 619–626Google Scholar
  582. Palos B, Kaplan HS, Karzmark CJ (1971) The use of “thin” lead lung shields to deliver limited whole lung irradiation during mantle field treatment of Hodgkin’s disease. Radiol 101: 441–442Google Scholar
  583. Paltauf R (1896) Lymphosarkom. Ergebnis allg. Path Anat 3: 652Google Scholar
  584. Papa G, Mauro FR, Anselmo AP, Cimino G, Alimena G, Amadori S, D’Arcangelo E, Giannarelli D, Bosi A, Bellesi G et al. (1984) Acute leukaemia in patients treated for Hodgkin’s disease. Br J Haematol 58: 43–52PubMedCrossRefGoogle Scholar
  585. Papadimitriou CS, Schwarze EW (1983) Extramedullary non-gastrointestinal plasmocytoma. Path Res Pract 176: 306–312PubMedCrossRefGoogle Scholar
  586. Papillon J (1974) The curability of Hodgkin’s disease. In: Musshoff K (ed) Diagnostic and therapy of malignant lymphoma. Springer, Berlin Heidelberg New York, pp 195–200Google Scholar
  587. Papillon J, Croizat P, Revol L, Chassard JL, Ferroldi J, Contamin A, Dutou L (1966 b) Les survie de plus de 10 ans dans la maladie de Hodgkin. Nouv rév franç hématol 6: 79–83Google Scholar
  588. Papillon J, Croizat P, Revol L, Chassard JL, Chassard E, Contamin A (1966 a) Le prognostic de la maladie de Hodgkin. J de radiol et d’électrol 47: 381–390Google Scholar
  589. Parlier Y, Gorin NC, Najman A, Stachowiak, Duhamel G (1982) Combination chemotherapy with cyclophosphamide, vincristine, prednisone and the contribution of adriamycin in the treatment of adult non-Hodgkin’s lymphomas. Cancer (Philad.) 50: 401–409CrossRefGoogle Scholar
  590. Parrish JA, Fitzpatrick TB, Tanenbaum L, Pathak MA (1974) Photochemotherapy of psoriasis with oral methoxsalen and long-wave ultraviolet light. New Engl J Med 291: 1207–1211PubMedCrossRefGoogle Scholar
  591. Paryani S, Hoppe RT, Burke JS, Sneet P, Dawly D, Cox RS, Rosenberg SA, Kaplan HS (1983)Google Scholar
  592. Extralymphatic involvement in diffuse non-Hodgkin’s lymphoma. J Clin Oncol 1:682–688Google Scholar
  593. Patel SP, Holtermann OA (1983) Mycosis fungoides: an overview. J Surg Oncol 22: 221–227PubMedCrossRefGoogle Scholar
  594. Paule B, Cosset JM (1984) La radiothérapie splénique comme alternative thérapeutique dans la leucémie lymphoide chronique. Bull Cancer 71: 72–73Google Scholar
  595. Paule B, Cosset JM, Le Bourgois JP (1985) The possible role of radiotherapy in chronic lymphocytic leukaemia: A critical review. Radiotherapy and Oncology 4: 45–54Google Scholar
  596. Peckham MJ (1973) Lung involvement in Hodgkin’s disease. In: Smithers Sir David (ed) Hodgkin’s disease. Churchill Livingstone, Edinburgh London, pp 118–127Google Scholar
  597. Peckham MJ (ed) (1975) Non-Hodgkin’s lymphomata, Symposium held at the Royal Institution, London, October 1973: Br J Cancer 31, Suppl 11: 1–511Google Scholar
  598. Peckham MJ, Ford HT, McElwain JT, Harmer CL, Atkinson K, Austin DE (1975) The results of radiotherapy for Hodgkin’s disease. Br J Cancer 32: 391–400PubMedCrossRefGoogle Scholar
  599. Pemsel HK, Jacobs C, Hess F, Kalbfleisch H (1978) Die Allgemeinsymptomatik bei der Hodgkinschen Erkrankung in ihrer Zuordnung zu anderen prognostischen Kriterien. Strahlenther 154: 758–765Google Scholar
  600. Peters LJ, Withers HR, CundiffJH, Dicke KA (1979) Radiobiological considerations in the use of total-body irradiation for bone-marrow transplantation. Radiol 131: 243–247Google Scholar
  601. Peters MV (1950) A study of survivals in Hodgkin’s disease treated radiologically. Am J Roentgenol 63: 299–311Google Scholar
  602. Peters MV (1966) Long term results of radical radiotherapy of Hodgkin’s disease. Cancer Res 26: 12–53Google Scholar
  603. Peters MV, Hasselback R, Brown TC (1968) The natural history of the lymphomas related to the clinical classification. In: Zararonetis CJD (ed) Proc. Intern. Conf. Leukemia-Lymphoma. Lea & Febiger, Philadelphia, pp 357–370Google Scholar
  604. Peters MV, Middlemiss KCH (1958) Study of Hodgkin’s disease treated by irradiation. Am J Roentgenol 79: 114–121Google Scholar
  605. Peters MV, Bush RS, Brown TC, Reid J (1975) The place of radiotherapy in the control of non-Hodgkin’s lymphomata. Br J Cancer 31, Suppl. 11: 386–401Google Scholar
  606. Pichler E, Jürgenssen OA, Radaszkiewicz T, Reinartz G, Mutz I, Urban Chr, Krepler P, Schmidmeier W, Becker H, Kundi M (1982) Results of LSA2–L2 therapy in 26 children with non-Hodgkin’s lymphoma. Cancer 50: 2240CrossRefGoogle Scholar
  607. Pinkel D (1971) Five-year follow-up of “total therapy” of childhood lymphocytic leukemia. J Am Med Ass 216: 648CrossRefGoogle Scholar
  608. Pinkel D (1976) Treatment of acute leukemia. Pediat Clin N Am 23: 117PubMedGoogle Scholar
  609. Pinkel D, Johnson W, Aur RJA (1975) Non-Hodgkin’s lymphoma in children. Br J Cancer 31, Suppl. 11: 298–323Google Scholar
  610. Pinkel D, Simone J, Hustu HO, Aur RJA (1972) Nine years experience with “total therapy” of childhood acute lymphocytic leukemia. Pediatrics 50: 246–251PubMedGoogle Scholar
  611. Poppema S (1980) The diversity of immunohistological staining pattern of Sternberg-Read-cells. J Histochem Cytochem 28: 788–791PubMedCrossRefGoogle Scholar
  612. Poppema S, Kaiserling E, Lennert K ( 1979 a) Nodular paragranuloma and progressively transformed germinal centers. Ultrastructural and immunohistologic findings. Virchows Arch (Cell Pathol) 31: 211–225Google Scholar
  613. Poppema S, Kaiserling E, Lennert K ( 1979 b) Hodgkin’s disease with lymphocytic predominance, nodular type (nodular paragranuloma) and progressively transformed germinal centers. A cytohistological study. Histopathology 3: 295–308Google Scholar
  614. Poppema S, Kaiserling E, Lennert K ( 1979 c) Epidemiology of nodular paragranuloma ( Hodgkin’s disease with lymphocytic predominance, nodular ). J Cancer Res Clin Oncol 95: 57–63Google Scholar
  615. Portlock CS, Rosenberg SA (1977) Chemotherapy of the non-Hodgkin’s lymphomas: The Stanford experience. Cancer Treat Rep 61: 1049–1055Google Scholar
  616. Portlock CS, Rosenberg SA (1979) No initial therapy for stage III and IV non-Hodgkin’s lymphomas of favorable histologic types. Ann Int Med 90: 10–13PubMedGoogle Scholar
  617. Portlock CS, Rosenberg SA, Glatstein E, Levy R, Kaplan HS (1977) Failure of initial therapy for stage I, II and III Hodgkin’s disease: salvage management ( Abstr ). Proc Am Soc Clin Oncol 18: 342Google Scholar
  618. Price RA, Jamieson PA (1975) The central nervous system in childhood leukemia. II. Subacute encephalopathy. Cancer 35: 306Google Scholar
  619. Probert JC, Parker BR, Kaplan HS (1973) Growth retardation in children after megavoltage irradiation of the spine. Cancer 32: 634–639PubMedCrossRefGoogle Scholar
  620. Prosnitz LR (1977) The Ann Arbor staging system for Hodgkin’s disease: does E stand for error. Int J Radiat Oncol Biol Phys 2: 1039Google Scholar
  621. Prosnitz LR (1983) The role of combination chemotherapy alone or as adjuvant to radiation therapy in limited stages of Hodgkin’s disease. In: Bennett JM (ed) Controversies in the management of lymphomas. Nijhoff, Boston, pp 151–166CrossRefGoogle Scholar
  622. Prosnitz LR, Curtis AM, Knowlton AH et al. (1980) Supradiaphragmatic Hodgkin’s disease: significance of large mediastinal masses. Int J Radiol Oncol Biol Phys 6: 809–813CrossRefGoogle Scholar
  623. Prosnitz LR, Hellman S, von Essen CF, Kligerman MM (1969) The clinical course of Hodgkin’s disease and other malignant lymphomas treated with radical radiation therapy. Am J Roentgenol 105: 618–628Google Scholar
  624. Prosnitz LR, Farber LR, Fischer JJ, Bertino JR (1973) Low-dose radiation therapy and combination chemotherapy in the treatment of advanced Hodgkin’s disease. Radiol 107: 187–193Google Scholar
  625. Prosnitz LR, Farber LR, Fischer JJ, Bertino JR, Fischer DB (1976) Long term remissions with combined modality therapy for advanced Hodgkin’s disease. Cancer 37: 2826–2833PubMedCrossRefGoogle Scholar
  626. Prosnitz LR, Rafael L, Montalvol BA, Fischer DB, Silberstein AB, Berger DS (1978) Treatment of stage III A Hodgkin’s disease: is radiotherapy alone adequate? Int J Radiat Oncol Biol Phys 4: 781–787PubMedGoogle Scholar
  627. Qasim MM (1981) Half body irradiation in metastatic carcinomas. Clin Radiol 32: 215–219PubMedCrossRefGoogle Scholar
  628. Qazi R, Aisenberg AC, Long JC (1976) The natural history of nodular lymphoma. Cancer 37: 1923–1927PubMedCrossRefGoogle Scholar
  629. Quaglino D, Artusi T, De Pasquale A, Paterlini P, Bonacorsi G (1982) Il paragranuloma nodulare. In: Silingardi V, Artusi T, Frederico M (eds) Il centro germinativo del follicolo linfatico. Pensiero Scientifico, Roma, pp 72–79Google Scholar
  630. Quast U (1982) Summary of the discussion on “in vitro” dosimetry. J Eur Radiother 3: 259–261Google Scholar
  631. Quast U (1985 a) Physical treatment planning of total-body irradiation: Patient translation and beam-zone method. Med Phys 12: 567–574Google Scholar
  632. Quast U (1985 b) Physical treatment planning of high energy photo beams. Review. Med Biol Eng Comp 23:190–191, Suppl 1Google Scholar
  633. Quast U (ed) (1986 a) Meeting of Essen 1985. Physical aspects and problems of total body irradiation. Seminar and workshop of the German Association of Medical Physics, DGMP, Physikalische Aspekte der Ganzkörperbestrahlung. Strahlenther 162: 211–278Google Scholar
  634. Quast U (1986 b) Physical problems of total body irradiation. Strahlenther 162:233–236Google Scholar
  635. Quast U (1986c) Problems of dose modification in total body irradiation. Review. Strahlenther 162: 271–275Google Scholar
  636. Quast U (1986) Physical aspects of dose homogenization. Med Phys 13 (to be published) Quesada JR, Reuben J, Manning JT, Hersh EM, Gutterman JU (1984) Alpha interferon for induction of remission in hairycell leukemia. N Engl J Med 310: 15–18CrossRefGoogle Scholar
  637. Quinton WD, Dillard D, Scribner BH (1962) Trans Am Soc Artif Int Org 8: 236CrossRefGoogle Scholar
  638. Radaszkiewicz T, Dragosics B (1980) Primary lymphomas of the gastrointestinal tract. A clinico-pathologic study of 60 cases. Path Res Pract 169: 353–365PubMedCrossRefGoogle Scholar
  639. Rai KR, Sawitsky A, Cronkite EP, Chanana AD, Levy RN, Pasternack BS (1975) Clinical staging of chronic lymphocytic leukemia. Blood 46: 219–234PubMedGoogle Scholar
  640. Rappaport H (1966) Tumors of the hematopoetic system. Atlas of tumor pathology, sect III, fasc 8. Armed Forces Institute of Pathology, Washington DC, pp 91–156Google Scholar
  641. Rappaport H (1977) Discussion. II: Roundtable discussion of histopathologic classification. Cancer Treatm Rep 61: 1037–1048Google Scholar
  642. Rappaport H (1980) Systemic manifestations of mycosis fungoides. In: van den Tweet JG, Taylor CR, Bosman FT (eds) Malignant lymphoproliferative diseases. Boerhaave Series, vol XVII. Leiden University Press, Boston, pp 369–372Google Scholar
  643. Rappaport H, Strum SB (1970) Vascular invasion in Hodgkin’s disease: its incidence and relationship to the spread of the disease. Cancer (Philad) 25: 1304–1313CrossRefGoogle Scholar
  644. Rappaport H, Thomas LB (1974) Mycosis fungoides: the pathology of extracutaneous involvement. Cancer 34: 1198–1229PubMedCrossRefGoogle Scholar
  645. Rappaport H, Winter WJ, Hicks EB (1956) Follicular lymphoma: a reevaluation of its position in the scheme of malignant lymphomas, based on a survey of 253 cases. Cancer (Philad) 9: 729–821CrossRefGoogle Scholar
  646. Rasmussen S, Dossing M, Walbom-Jorgensen S (1978) Coronary heart disease — a possible risk in megavoltage therapy? Acta Med Scand 203: 237–239PubMedCrossRefGoogle Scholar
  647. Ratkóczy N (1936) Herdvemichtungsdosen in der Röntgentherapie der Lymphogranulomatose. Strahlenther 56: 325–336Google Scholar
  648. Reddy S, Saxena VS, Pelletiere EV, Hendrickson F (1977) Early nodal and extranodal non-Hodgkin’s lymphomas. Cancer 40: 98–104PubMedCrossRefGoogle Scholar
  649. Reed DM (1902) On the pathological changes in Hodgkin’s disease, with special reference to its relation to tuberculosis. Johns Hopkin Hosp Rep 10: 133–196Google Scholar
  650. Renner H (1973) Strahlentherapeutische Aspekte des multiplen Myeloms. Strahlenther 146: 1523Google Scholar
  651. Revol L, Viala JJ, Guyon JM (1975) A propos de la radiothérapie splénique dans la leucémie myéloide; étude comparative avec la chimiothérapie. Nouv rev franç hémat 15: 245–249PubMedGoogle Scholar
  652. Revol L, Cordat M, Rouhier D, Clavel M, Jeune R, Guyon JM, Chassard JL, Papillon J (1974) Quelques considération sur la radiothérapie dans la leucémie myéloide chronique. Strahlenther 148: 572–578Google Scholar
  653. Rhyner K, Blättner W, Bauer W, Bollinger A (1979) Die primäre Thrombozythaemie: Klinik, Pathophysiologie und Therapiemöglichkeiten. Schweiz Med Wschr 109: 467–471Google Scholar
  654. Richards JDM, Coates PH, Closs SP, Tobias JS, Joannides T (1983) Case of macroglobulinaemia treated with hemibody irradiation. Lancet 11: 844CrossRefGoogle Scholar
  655. Rider WD, Van Dyk J (1983) Total and partial body irradiation. In: Bleehen NM, Glatstein EGoogle Scholar
  656. Haybittle JL (eds) Radiation therapy treatment planning. Dekker, New York, pp 559–594Google Scholar
  657. Riehm H, Gadner H, Henze G et al. (1980) The Berlin childhood acute lymphoblastic leukemia therapy study, 1970–1976. Am J Pediatr Hematol Oncol 2: 299Google Scholar
  658. Riehm H, Gadner H, Welte K (1977) Die West-Berliner Studie zur Behandlung der akuten lymphoblastischen Leukämie des Kindes — Erfahrungsbericht nach 6 Jahren. KIM Pädiat 189: 89–102Google Scholar
  659. Riehm H, Henze G, Jobke A et al. (1982) BFM study therapy results in childhood acute lymphoblastic leukemia (ALL) and non-Hodgkin’s lymphoma (NHL), a one decade’s experience in 388 patients. In: Pediatric oncology. Excerpta Medica, Amsterdam Oxford Princeton, p 350Google Scholar
  660. Riehm H, Gadner H, Henze G, Kornhuber B, Langermann HJ, Müller-Weihrich St., Schellong G (1983) Acute lymphoblastic leukemia: treatment, results in three BFM studies (1970–1981). In: Murphy ShB, Gilbert JR (eds) Leukemia research: advances in cell biology and treatment. Elsevier, Amsterdam, pp 251–260Google Scholar
  661. Riemann JF, Hoerder U, Rödl W (1983) Gastrointestinale Manifestation maligner Systemerkrankungen. Fortschr Med 101: 315–319PubMedGoogle Scholar
  662. Rodgers RW, Fuller LM, Hagemeister FB, Johnston DA, Sullivan JA, North L, Butler JJ, Velasquez WS, Conrad FG, Shullenberger CC (1981) Reassessment of prognostic factors in stage III A and II B Hodgkin’s disease treated with MOPP and radiotherapy. Cancer 47: 2196–2203PubMedCrossRefGoogle Scholar
  663. Rodriguez V, Cabanillas F, Burgess MA, McKelvey EM, Valdivieso M, Bodey GP (1977) Combination chemotherapy „CHOPP-Bleo“ in advanced (non-Hodgkin) lymphoma. Blood 49: 325–333PubMedGoogle Scholar
  664. Roenigk HH Jr (1979) Photochemotherapy for mycosis fungoides: Long-term follow-up study. Cancer Treatm Rep 63: 669–673Google Scholar
  665. Roos G, Dige U, Lenner P, Lindh J, Johannson H (1985) Prognostic significance of DNA-ana-lysis by cytometry in non-Hodgkin’s lymphoma. Hematological Oncol 3: 233–242CrossRefGoogle Scholar
  666. Rosenberg SA (1966) Report of the Staging Committee of Hodgkin’s disease. Cancer Res 26: 1310Google Scholar
  667. Rosenberg SA (1978) The management of Hodgkin’s disease. N Engl J Med 299: 1246–1247PubMedCrossRefGoogle Scholar
  668. Rosenberg SA (1979) Non-Hodgkin’s lymphoma — Selection of treatment on the basis of histologic type. N Engl J Med 301: 924–928PubMedCrossRefGoogle Scholar
  669. Rosenberg SA (1985) Laparotomy and splenectomy in Hodgkin’s disease: A reappraisal after twenty years. Scand J Haematol 34: 289–292PubMedCrossRefGoogle Scholar
  670. Rosenberg SA, Kaplan HS (1966) Evidence for an orderly progression in the spread of Hodgkin’s disease. Cancer Res 26: 1225–1230PubMedGoogle Scholar
  671. Rosenberg SA, Kaplan HS (1970) Hodgkin’s disease and other malignant lymphomas. Calif Med 113: 23–38PubMedGoogle Scholar
  672. Rosenberg SA, Kaplan HS (1975 b) Clinical trials in the non-Hodgkin’s lymphomata at Stanford University experimental design and preliminary results. Br J Cancer 31, Suppl II: 456–464Google Scholar
  673. Rosenberg SA, Kaplan HS ( 1975 b) The management of stages I, II and III Hodgkin’s disease with combined radiotherapy and chemotherapy. Cancer 35: 55–63Google Scholar
  674. Rosenberg SA, Kaplan HS (1985) The evolution and summary results of the Stanford randomized clinical trials of the management of Hodgkin’s disease: 1962–1984. Int J Radiat Oncol Biol Phys 11: 5–22PubMedCrossRefGoogle Scholar
  675. Rosenberg SA, Moore MR, Bull JM, Jones SE, Kaplan HS (1972) Combination chemotherapy and radiotherapy for Hodgkin’s disease. Cancer 30: 1505–1510PubMedCrossRefGoogle Scholar
  676. Rosenberg SA, Kaplan HS, Hoppe RT, Kushlan P, Horning S (1982) The Stanford randomized trials of the treatment of Hodgkin’s disease: 1967–1980. In: Rosenberg SA, Kaplan HS (eds) Malignant lymphomas: etiology, immunology, pathology, treatment. Academic Press, New York, pp 513–522Google Scholar
  677. Rosenbloom M (1982) Summary of the discussion on homogeneity of dose distribution. J Eur Radiother 3: 252–254Google Scholar
  678. Rosner F, Grunwald H (1975) Hodgkin’s disease and acute leukemia. Am J Med 58: 339–353PubMedCrossRefGoogle Scholar
  679. Roth H, Daum R, Bolkenius M (1982) Partielle Milzresektion und Fibrinklebung — Eine Alternative zur Splenektomie und Autotransplantation. Z Kinderchir 35: 153PubMedGoogle Scholar
  680. Roth J (1982) Summary of the discussion on patient position and beam direction. J Eur Radiother 3: 249–250Google Scholar
  681. Roth J (1984) Ganzkörperbestrahlung. Tagungsbericht der Schweizerischen Gesellschaft für Strahlentherapie und Strahlenphysik. Huber, KerzersGoogle Scholar
  682. Roth J (1986) Physical treatment planning for total-body irradiation. Review. Strahlenther 162: 276–278Google Scholar
  683. Rous P (1911) Transmission of a malignant new growth by means of cell-free filtrate. J Am Med Ass 56: 198–201Google Scholar
  684. Rowland CG (1979) Single fraction half body irradiation therapy. Clin Radiat 30: 1–3CrossRefGoogle Scholar
  685. Rowland CG, Bullimore J, Smith PJB, Roberts JBM (1981) Halfbody irradiation in the treatment of metastatic prostatic carcinoma. Br J Urol 53: 628–629PubMedCrossRefGoogle Scholar
  686. Rowland CG, Garret MJ, Crowley FA (1983) Half body radiation in plasma cell myeloma. Clin Radiol 34: 507–510PubMedCrossRefGoogle Scholar
  687. Rozman C, Hernandez nieto L, Montserrat E, Brugues R (1981) Prognostic significance of bone marrow patterns in chronic lymphocytic leukemia. Br J Haematol 47: 529–537PubMedCrossRefGoogle Scholar
  688. Rubin P (1984) The Franz Buschke Lecture: Late effects of chemotherapy and radiation therapy. A new hypothesis. Int J Radiat Oncol Biol Phys 10: 5–34PubMedGoogle Scholar
  689. Rubin P, Bennett JM, Begg C, Bozdech MJ, Silber R (1981) The comparison of total body irradiation vs chlorambucil and prednisone for remission induction of active chronic lymphocytic leukemia: an ECOG study. I. Total body irradiation-response and toxicity. Int J Radiat Oncol Biol Phys 7: 1623–1632Google Scholar
  690. Rudders RA, Ross ME, DeLellis RA (1978) Primary extranodal lymphoma. Response to treatment and factors influencing prognosis. Cancer 42: 406–416Google Scholar
  691. Russel KJ, Hoppe RT, Colby TV, Burns BF, Cox RS, Kaplan HS (1983) Lymphocytic predominant Hodgkin’s disease: clinical presentation and results of treatment. Radiother Oncol 1: 197–202CrossRefGoogle Scholar
  692. Sack H (1986) Kontrollierte Studie über die Therapie der Non-Hodgkin-Lymphome hoher Malignität des Stadiums I, der niedrig malignen Non-Hodgkin-Lymphome der Stadien I und II und der zentrozytisch-zentralblastischen Lymphome der Stadien I—IIIGoogle Scholar
  693. Salazar OM, Rubin P, Keller B, Scarantino C (1978) Systemic (half body) radiation therapy: response and toxicity. Int J Radiat Oncol Biol Phys 4: 937–950PubMedGoogle Scholar
  694. Saleem A, Johnston RL (1980) Acute lymphoblastic leukemia following Hodgkin’s disease. Ann Clin Lab Sci 10: 100–104PubMedGoogle Scholar
  695. Sallan SE, Weinstein HJ, Nathan DG (1981) The childhood leukemias. J Pediatr 99:676 Salzman JR, Kaplan HS (1971) Effect of prior splenectomy on haematological tolerance during total lymphoid radiotherapy of patients with Hodgkin’s disease. Cancer 27: 471–478Google Scholar
  696. Santoro A, Bonfante V, Bonadonna G, Zuccoli R, Pagnoni AM, Valagussa P, Banfi A (1981) Therapeutic and toxilogic effects of MOPP vs ABVD combined with radiotherapy in Hodgkin’s disease. In: Salman SE, Jones SE (eds) Adjuvant therapy of cancer. III. Grune and Stratton, New York, pp 85–91Google Scholar
  697. Santoro A, Bonadonna G, Bonfante V, Valagussa P (1982) Alternating drug combination in the treatment of advanced Hodgkin’s disease. N Engl J Med 306: 770–775PubMedCrossRefGoogle Scholar
  698. Santoro A, Viviani S, Zucali R, Ragni G, Bonfante V, Valagussa P, Banfi A, Bonadonna G (1984) Comparative results and toxicity of MOPP vs ABVD combined with radiotherapy in PS II B, III (A, B) Hodgkin’s disease. ASCO Abstracts C-872Google Scholar
  699. Schaadt M, Diehl V, Stein H, Fonatsch C, Kirchner HH (1980) Two neoplastic cell lines with unique features derived from Hodgkin’s disease. Int J Cancer 26: 723–731PubMedCrossRefGoogle Scholar
  700. Schaefer UW, Mahmoud HK, Schüning F, Schmidt CG, Becher R, Nowrousian MR, Öhl S, Wetter O, Bamberg M, Alberti W, Schmitt G, Quast U, Scherer E, Haralambie E, Linzenmeier G, Grosse-Wilde H, Kuwert E, Henneberg KB, Luboldt W, Richter HJ, Leder LD, Hantschke D (1984) Knochenmarktransplantationen bei Panmyelopathie und Leukämien. DMW 109: 1909–1913CrossRefGoogle Scholar
  701. Schaefer UW, Mahmoud HH, Beelen DW, Hoffmann W, Becher R, Schmidt CG, Bamberg M, Quast U, Haralambie E, Linzenmeier G, Stollmann B, Grosse-Wilde H, Richter HJ, Hantschke D, Henneberg K, Luboldt W (1986) Bone marrow transplantation in severe aplastic anemia and acute or chronic leukemia. Strahlenther 162: 214–217Google Scholar
  702. Schellong G (1977) Akute Leukämie bei Kindern. Dtsch Ärztebl 75: 757Google Scholar
  703. Schellong G (1985) Kooperative Therapiestudie HD 85 zur Behandlung des Morbus Hodgkin bei Kindern. Deutsche Arbeitsgemeinschaft für Leukämieforschung und -behandlung im Kindesalter e. V.Google Scholar
  704. Schellong G, Waubke AK, Langermann H, Breu B, Kuhne B, Riehen H, Ritter J (1982) Bedeutung klinischer und intraoperativer Befunde für die Voraussage eines Milzbefalls beim Morbus Hodgkin im Kindesalter. Eine retrospektive statistische Analyse bei 154 Patienten der Therapiestudie HD 78. Klin Pädiat 194: 242–258CrossRefGoogle Scholar
  705. Schellong G, Brämswig J, Ludwig R, Gerein V, Jobke A, Jürgens H, Kabisch H, Stollmann B, Weinel P, Gadner H, Schwarze EW, Wannenmacher M (1986 a) Kombinierte Behandlungsstrategie bei über 200 Kindern mit Morbus Hodgkin: Abgestufte Chemotherapie, InvolvedField-Bestrahlung mit erniedrigten Dosen und selektive Splenektomie. Ein Bericht der kooperativen Therapiestudie DAL-HD-82. Klin Pädiat 198: 137–146Google Scholar
  706. Schellong G, Lietzke S, Strauch St, Kuhne B, Schneider B (1986 b) Bedeutung sonographischer, computertomographischer und klinischer Befunde für die Erkennung eines Abdominalbefalls beim Morbus Hodgkin im Kindesalter–Eine retrospektive Analyse bei 145 Patienten der Therapiestudie DAL-HD-82. Klin Pädiat 198: 147–154Google Scholar
  707. Schellong G, Waubke-Landwehr A-K, Langermann H-J, Riehm H-J, Brämswig J, Ritter J, for the Hodgkin’s disease therapy study group DAL-HD-78 (1986 c) Prediction of splenic involvement in children with Hodgkin’s disease. Significance of clinical and intraoperative findings. A retrospective statistical analysis of 154 patients in the german therapy study DAL-HD-78. Cancer 57: 2049–2056Google Scholar
  708. Schmähl D, Habs M (1981) Drug-induced Cancer. IARC MonographieGoogle Scholar
  709. Schmalhorst U, Bartels H, Boll I, Burger-Schüler A, Common H, Fülle HH, Graubner M, Heinz R, Huhn D, Leopold H, Meusers P, Nowicki L, Nürnberger R, Oertel J, Rühl U, Sieber G, Schmidt M, Schoengen A, Strassner A, Schwarze EW, Brittinger G (Kiel Lymphoma Study Group) (1981) Clinical and prognostic heterogeneity of non-Hodgkin lymphomas of high-grade malignancy. Blut 43: 201–211CrossRefGoogle Scholar
  710. Schmauz R, Mugerwa JW, Owor R (1983) Maligne Nicht-Hodgkin-Lymphome im tropischen Afrika. Verh Dtsch Ges Path 67: 655Google Scholar
  711. Schmid U, Gloor F, Schildknecht 0 (1980) Das maligne Nicht-Hodgkin-Lymphom des Magens. Dtsch Med Wschr 105: 1147–1152Google Scholar
  712. Schmidt-Vollmer H, Musshoff K, Lennert K, Sandritter W, Stiefelhagen H (1975) Vorläufige Befunde zur Prognose der Kiel Klassifikation der malignen Non-Hodgkin-Lymphome. Gemeinsame Tagung der Deutschen und der Österreichischen Gesellschaft für Hämatologie, Bad Nauheim 29.9.-1. 10. 1975Google Scholar
  713. Schneider JS, Edwards JE (1979) Irradiation-induced pericarditis. Chest 75: 560–564PubMedCrossRefGoogle Scholar
  714. Schneider RJ, Seibert K, Passe S, Little C, Gee T, Lee III BJ, Mike V, Young CW (1980) Prognostic significance of serum lactate dehydrogenase in malignant lymphoma. Cancer 46: 139–143PubMedCrossRefGoogle Scholar
  715. Schoen D, Bauer R (1968) Ergebnisse der Milzbestrahlung bei 175 Fällen mit chronisch-myeloischer Leukämie. Strahlenther 135: 1–10Google Scholar
  716. Schoen HD (1972) Strahlentherapie der chronischen Leukose. In: Gross R, van de Loo J (Hrsg) Leukämie Springer, Berlin Heidelberg New York, S 595–616Google Scholar
  717. Schoen HD (1972) Strahlentherapie der chronischen Leukose. In: Gross R, van de Loo J (Hrsg) Leukämie Springer, Berlin Heidelberg New York, S 595–616Google Scholar
  718. Schulz U, Malewski N, Alberti W (1985) Prognostische Faktoren bei der Verlaufskontrolle der Lymphogranulomatose: Vergleich zweier Therapietechniken mit Analyse serologischer Parameter. Strahlenther 161: 221–224Google Scholar
  719. Schwab U, Stein H, Gerdes J, Lemke H, Kirchner H, Schaadt M, Diehl V (1982) Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin’s disease and a subset of normal lymphoid cells. Nature 299: 65PubMedCrossRefGoogle Scholar
  720. Schwarze EW (1983) Primär extranodale Non-Hodgkin Lymphome: Ihre Histopathologie, bevorzugte Lokalisation, Häufigkeit und Pathogenese. Symposium der Arbeitsgemeinschaften für Internistische und Radiotherapeutische Onkologie der Deutschen Krebsgesellschaft e. V. Hahnenklee/Harz 10.-12. 2. 1983Google Scholar
  721. Schwarze EW (1986) Non-Hodgkin-Lymphome. Cytologie und Cytochemie. In: Seifert G (Hrsg) Veröffentlichungen aus der Pathologie. Fischer, Stuttgart New York Bd 123: 1–241Google Scholar
  722. Scott EJ van, Kalmanson JD (1973) Complete remissions of mycosis fungoides lymphoma induced by topical nitrogen mustard (HN2), control of delayed hyper sensitivity to HN2 by desensitization and by induction of specific immunologic tolerance. Cancer 32: 18–30PubMedCrossRefGoogle Scholar
  723. Semenzato G, Pezzoto A, Agostini C, Abertin M, Gasporateo G (1981) T lymphocytes subpopulations in chronic lymphocytic leukemia. Cancer 48: 2191–2197PubMedCrossRefGoogle Scholar
  724. Shackney SE, Skramstad KS, Cunningham R, Dugas DJ, Lincoln TL, Lukes RJ (1980) Dual parameter flow cytometry studies in human lymphomas. J Clin Invest 66: 1281–1294PubMedCrossRefGoogle Scholar
  725. Shah I, Lewkow LM, Khilanani U (1983) Correlation of hypercupremia with other acute phase reactants in malignant lymphoma. Cancer 51: 851–854PubMedCrossRefGoogle Scholar
  726. Shank B (1983) Techniques of magna-field irradiation. Int J Radiat Oncol Biol Phys 9: 1925–1931PubMedGoogle Scholar
  727. Shank B, Hopfan S, Kim JH, Chu F, Grossbard E, Kapoor N, Kirkpatrick D, Dinsmore R, Simpson L, Reid A, Chui C, Mohen R, Finegan D, O’Reilly F (1981) Hyperfractionated total body irradiation for bone marrow transplantation: early results in leukemia patients. Int J Radiat Oncol Biol Phys 7: 1109–1115PubMedCrossRefGoogle Scholar
  728. Sharp JC, Joyner MV, Wayne AW, Kemp J, Crofts M, Birch ADJ, McArthur G, Lai S, Stern-dale H, Williams Y (1979) Karyotypic conversion in Ph1-positive chronic myeloid leukaemia with combination chemotherapy. Lancet 1: 1370–1372PubMedCrossRefGoogle Scholar
  729. Sherlock P (1980) The gastrointestinal manifestations and complications of malignant lymphomas. Schweiz Med Wschr 110: 1031–1037PubMedGoogle Scholar
  730. Sickinger K, Musshoff K, Stephan F, Appels A (1965) Resorptionsstudien nach Röntgenbestrahlung des Abdomens bei maligner Lymphogranulomatose unter Verwendung des D-Xylose-Resorptionstests und des J131-Trioleintests. Strahlenther 128: 340–346Google Scholar
  731. Silverstein MN (1976) The evolution into and the treatment of late stage polycythemia vera. Semin Hemat 13: 79–84PubMedGoogle Scholar
  732. Silverstein MN (1983) Primary thrombocythemia. In: Beutler E, Ersley AJ, Lichtmann MA (eds) Hematology. McGraw-Hill, New York, pp 218–221Google Scholar
  733. Silvestrini R, Piazza R, Rilke A (1977) Correlation of cell kinetic findings with morphology of non-Hodgkin’s malignant lymphomas. J Natl Cancer Inst 58: 499–504PubMedGoogle Scholar
  734. Simone JV, Cassady JR, Filler RM (1982) Cancers of childhood. In: De Vita VT Jr, Hellman S, Rosenberg StA (eds) Cancer: principles and practice of oncology. JB Lippincott, Philadelphia Toronto, pp 1254–1330Google Scholar
  735. Simone JV, Aur RJA, Hustu HO, Verzosa M, Pinkel D (1975) Combined modality therapy of acute lymphocytic leukemia. Cancer 35: 25PubMedCrossRefGoogle Scholar
  736. Simone JV, Aur RJA, Hustu HO, Verzosa M (1975) Acute lymphocytic leukemia in children. Cancer 36: 770PubMedCrossRefGoogle Scholar
  737. Simone JV, Aur RJA, Hustu HO, Verzosa MS, Pinkel D (1978) Three to ten years cessation of therapy in children with leukemia. Cancer 42: 839–844PubMedCrossRefGoogle Scholar
  738. Skipper HE, Schabel FM Jr, Wilcox WS (1964) Experimental evaluation of potential anticancer agents. XIII. On the criteria and kinetics associated with “curability” of experimental leukemia. Cancer Chemother Rep 35: 3–111Google Scholar
  739. Slanina J, Musshoff K, Rahner T, Stiasny R (1977) Longterm side effects in irradiated patients with Hodgkin’s disease. Int J Radiation Oncology Biol Phys 2: 1–19Google Scholar
  740. Slanina J, Kuphal K, Riegsinger A (1980) Anwendung des Split-Course-Verfahrens bei der totalnodalen Systembestrahlung der Hodgkinschen Erkrankung. Strahlenther 156: 18–25Google Scholar
  741. Slanina H, Wannenmacher M, Heidemann S (1982) Infektgefährdung durch iatrogene Asplenie. Ein Beitrag zur Indikation der explorativen Laparotomie mit Splenektomie bei Morbus Hodgkin. Strahlenther 158: 395–404Google Scholar
  742. Slanina J, Wannenmacher M, Spratler J (1985) Schwangerschaft und Kindesentwicklung nach Therapie des Morbus Hodgkin. Strahlenther 161: 558–564Google Scholar
  743. Slanina J, Wannenmacher M, Widmaier S (1981) Die Bedeutung einer umfassenden Strahlentherapie für die Prognose des zentroblastisch-zentrozytischen Lymphoms bzw. des großfollikulären Lymphoms Brill-Symmers (Freiburger Ergebnisse 1965–1979). Strahlenther 157: 516523Google Scholar
  744. Slanina J, Fröhlich J, Oehlert W, Hoppe-Seyler P, Neidl K, Wannenmacher M (1985) Endoskopisch-bioptische Befunde bei Oesophagus-, Magen-und Duodenalschleimhaut vor und nach Strahlentherapie bei Morbus Hodgkin. Strahlenther 161: 216–220Google Scholar
  745. Smith BR, Weinberg DS, Robert NJ, Towle M, Luther E, Pinkus GS, Ault KA (1984) Circulating monoclonal B lymphocytes in non-Hodgkin’s lymphoma. N Engl J Med 311: 1476–1481PubMedCrossRefGoogle Scholar
  746. Song CW, Kim TH, Khan FM, Kersey JH, Levitt SH (1981) Radiobiological basis of total body irradiation with different dose rates and fractionation: repair capacity of hemopoietic cells. Int J Radiat Oncol Biol Phys 7: 1695–1701PubMedCrossRefGoogle Scholar
  747. Speck B, Gratwohl A, Osterwalder B, Nissen C (1984) Bone marrow transplantation for chronic myeloid leukemia. Semin Haematol 21: 48–56Google Scholar
  748. Stacher A (1985) Myeloproliferative Syndrome. In: Gross R, Schmidt CG (Hrsg) Klinische Onkologie. Thieme, Stuttgart New York, S 44. 1–9Google Scholar
  749. Stacher A, Waldner R, Theml H (Kieler Lymphomgruppe) (1976) Klinik der malignen NonHodgkin-Lymphome entsprechend der Kieler Klassifikation: Lymphoplasmozytoides Lymphom (LPL) und chronisch lymphatische Leukämie (CLL). In: Löffler H (Hrsg) Maligne Lymphome und monoklonale Gammopathien, Bd XVIII: Hämatologie und Bluttransfusion. Lehmann, München, S 199–209Google Scholar
  750. Stein H (1980) Einteilung, Histologie und Natur der Non-Hodgkin-Lymphome. In: Musshoff K, Slanina J: Maligne Systemerkrankungen. In: Scherer E (Hrsg) Strahlentherapie, 2. Auflage, p 908Google Scholar
  751. Stein H, Bonk A, Tolksdorf G, Lennert K, Rodt H, Gerdes J (1980) Immunhistologic analysis of the organization of normal lymphoid tissue and non-Hodgkin’s lymphomas. J Histochem Cytochem 28: 746–760PubMedCrossRefGoogle Scholar
  752. Stein H (1982) Systematik der Non-Hodgkin-Lymphome. In: Begemann H (Hrsg) Handbuch der Inneren Medizin Blut und Blutkrankheiten, 5. Aufl, II/7. Springer, Berlin Heidelberg New York, S 1–79Google Scholar
  753. Stein H (1983) Immunologie und Morphologie der malignen Lymphome. Verh dtsch Ges Path 67: 1983 (Übersicht)Google Scholar
  754. Stein H, Gerdes J, Mason DY (1982 b) The normal and malignant germinal centre. Clin Haemat 11: 531–560Google Scholar
  755. Stein H, Gerdes J, Schwab U, Lemke H, Mason DY, Ziegler A, Schienle W, Diehl V (1982 a) Identification of Hodgkin and Sternberg-Reed cells as a unique cell type derived from a newly-detected small-cell population. Int J Cancer 30: 445Google Scholar
  756. Stein H, Gerdes J, Schwab U, Lemke H, Diehl V, Mason DY, Bartels H, Ziegler A (1983) Evidence for the detection of the normal counterpart of Hodgkin and Sternberg-Reed cells. Hematol Oncol 1: 21–29PubMedCrossRefGoogle Scholar
  757. Stein H, Gerdes J, Lemke H, Burrichter H, Diehl V, Gatter K, Mason DY (1984a) Hodgkin’s disease and so-called malignant histiocytosis: neoplasmas of a new cell type? Control Oncol 19: 88Google Scholar
  758. Stein H, Lennert K, Feller A, Mason DY (1984b) Immunohstological analysis of human lymphoma: correlation of histiological and immunological categories. Adv Cancer Res 42: 67147Google Scholar
  759. Stein H, Mason DY ( 1985 a) Immunological analysis of tissue sections in diagnosis of lymphoma. In: Hoffbrand AV (ed) Recent advances in haematology, no 4. Churchill Livingstone, Edinburgh London Melbourne New YorkGoogle Scholar
  760. Stein H, Gerdes J, Lemke H, Mason DY ( 1985 b) Evidences of Sternberg-Reed cells being derived from activated lymphocytes. In: Modern trends in human leukemia. V. Haematol Blood Transfusion 29: 441Google Scholar
  761. Stein H, Mason DY, Gerdes J, O’Connor N, Wainscoat J, Pallesen G, Gatter K, Falini B, Delsol G, Lemke H, Schwarting R, Lennert K (1985 c) The expression of the Hodgkin’s disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 66: 848–858Google Scholar
  762. Stein H, Gerdes J (1986 a) Phänotypische und genotypische Marker bei malignen Lymphomen: ein Beitrag zum zellulären Ursprung des Morbus Hodgkin und der malignen Histiozytose sowie Implikationen für die Klassifikation der T-Zell-und B-Zell-Lymphome. Verh Dtsch Ges Path 70: 127–151Google Scholar
  763. Stein H, Gerdes J (1986 a) Phänotypische und genotypische Marker bei malignen Lymphomen: ein Beitrag zum zellulären Ursprung des Morbus Hodgkin und der malignen Histiozytose sowie Implikationen für die Klassifikation der T-Zell-und B-Zell-Lymphome. Verh Dtsch Ges Path 70: 127–151Google Scholar
  764. Stein H, Gerdes J (1986 a) Phänotypische und genotypische Marker bei malignen Lymphomen: ein Beitrag zum zellulären Ursprung des Morbus Hodgkin und der malignen Histiozytose sowie Implikationen für die Klassifikation der T-Zell-und B-Zell-Lymphome. Verh Dtsch Ges Path 70: 127–151Google Scholar
  765. Stein RS (1978) Mycosis fungoides with pulmonary involvement. Arch Dermatol 114:247–249 Stein RS, Hilborn RM, Flexner M, Bolin M, Stroup St, Reynolds V, Krantz S (1978) Anatomical substages of stage III Hodgkin’s disease, implications for staging, therapy, and experimental design. Cancer 42: 429–436PubMedCrossRefGoogle Scholar
  766. Stein RS, Golomb HM, Diggs CH, Mauch P, Hellman S, Wiernik PH, Ultmann JE, Rosenthal DS (1980) Anatomic substages of stage III-A Hodgkin’s disease. A collaborative study. Ann Intern Med 92: 159–165Google Scholar
  767. Stein RS, Golomb HM, Wiernik PH, Mauch P, Hellman S, Ultmann JE, Rosenthal DA, Flexner JM (1982) Anatomic substages of stage III-A Hodgkin’s disease: a follow-up of a collaborative study. Cancer Treatm Rep 66: 733–742Google Scholar
  768. Stein RS (1983) Chemotherapy for stage III-A Hodgkin’s disease: the proper role. In: Bennett JM (ed) Controversies in the management of lymphomas. Nijhoff, Boston The Hague Dordrecht Lancaster, pp 167–181CrossRefGoogle Scholar
  769. Steinke B, Gärtner HV, Ostendorf P, Waller HD (1984) Klinik und Therapie des malignen Lymphoms vom Burkitt-Typ bei Erwachsenen. Eine Übersicht anhand von 14 Fällen. Tumordiagn Ther 5: 1–6Google Scholar
  770. Sternberg C (1898) Über eine eigenartige unter dem Bilde der Pseudoleukämie verlaufende Tuberkulose des lymphatischen Apparates. Z Heilk 19: 21–90Google Scholar
  771. Steward WP, Todd IDH, Harris M, Jones JM, Blackledge G, Wagstaff J, Anderson H, Wilkinson PM, Crowther C (1984) A multivariate analysis of factors affecting survival in patients with high-grade histology non-Hodgkin’s lymphoma. Eur J Cancer Clin Oncol 20: 881–889PubMedCrossRefGoogle Scholar
  772. Stickle G (1968) Defective development and reproductive wastage in the United States. Am J Obst Gynecol 100: 442–447Google Scholar
  773. Storb R, Thomas ED (1984) Allogenic bone marrow transplantation. Immun Rev 71:77–85 Strauchen JA, Young RC, DeVita VT Jr, Anderson T, Fantone JC, Berard CW (1978) Clinical relevance of the histopathological subclassification of diffuse “histiocytic” lymphoma. N Engl J Med 299: 1382–1387Google Scholar
  774. Streffer Chr (1976) Biologische Grundlagen der Strahlentherapie. In: Scherer E (Hrsg) Strahlentherapie — Radiologische Onkologie. Springer, Berlin Heidelberg New York, S 172–230Google Scholar
  775. Streffer Chr (1986) Biologische Grundlagen der Strahlentherapie. In: Scherer E (Hrsg) Strahlentherapie, 3. Aufl. Springer, Berlin Heidelberg New YorkGoogle Scholar
  776. Streuli R, Maurer R, Graf C, Rhyner K (1983) Non-Hodgkin-Lymphome des Hodens. Schweiz Med Wschr 113: 771–778PubMedGoogle Scholar
  777. Strickstrock KH, Musshoff K, Boutis L (1967) Methode der zusätzlichen prophylaktischen Bestrahlung bei der Lymphogranulomatose. Strahlenther 133: 337–348Google Scholar
  778. Strum SB, Park JK, Rappaport H (1970) Observation of cells resembling Sternberg-Reed cells in conditions other than Hodgkin’s disease. Cancer 26: 176–190PubMedCrossRefGoogle Scholar
  779. Stutzman L, Glidewell O (1973) Multiple chemotherapeutic agents for Hodgkin’s disease—Comparison of three routines — A cooperative study by acute leukemia group B. JAMA 225: 1202–1211PubMedCrossRefGoogle Scholar
  780. Sukiennikow W (1903) Topographische Anatomie der bronchialen und trachealen Lymphdrüsen. Berl Klin Wschr 40:316, 347, 369Google Scholar
  781. Sutcliffe SB, Gospodarowicz MK, Bush RS, Brown ThC, Chua Th, Bean HA, Clark RM, Dembo A, Fitzpatrick PJ, Peters MV (1985) Role of radiation therapy in localized non-Hodgkin’s lymphoma. Radiother Oncol 4: 211–223PubMedCrossRefGoogle Scholar
  782. Sweet DL, Kinzie J, Gaeke ME (1981) Survival of patients with localized diffuse histiocytic lymphoma. Blood 58: 1218–1233PubMedGoogle Scholar
  783. Symmers D (1927) Follicular lymphadenopathy with splenomegaly. A newly recognized disease of the lymphatic system. Arch Pathol 3: 816Google Scholar
  784. Tadros AAM, Tepperman BS, Hryniuk WM, Peters VG, Rosenthal D, Roberts JT, Figueredo AT (1983) Total skin electron irradiation for mycosis fungoides: failure analysis and prognostic factores. Int J Radiat Oncol Biol Phys 9: 1279–1287PubMedCrossRefGoogle Scholar
  785. Takâcsi-Nagy L, Tarkovâcs G, Szende B, Graf F (1978) A clinicopathological study of non-Hodgkin’s lymphomas in terms of the Kiel classification. Folia Haemat 105: 79–92Google Scholar
  786. Taylor C (1976) An immunohistochemical study of follicular lymphome, reticulum cell sarcoma and Hodgkin’s disease. Eur J Cancer 61: 61–75Google Scholar
  787. Tepperman BS, Gospodarowicz MK, Bush RS, Brown TC (1982) Non-Hodgkin’s lymphoma of the testis. Radiol 142: 203–208Google Scholar
  788. Teschendorf W (1927) Über Bestrahlung des ganzen menschlichen Körpers bei Blutkrankheiten. Strahlenther 26: 720–728Google Scholar
  789. Teschendorf W (1953) Die Teleröntgentherapie. Thieme, StuttgartGoogle Scholar
  790. Teschendorf W (1970) Ganzkörper-und Abschnittsbestrahlung beim Menschen. In: Handbuch der medizinischen Radiologie — Encyclopedia of medical radiology. Springer, Berlin Heidelberg New YorkGoogle Scholar
  791. Thar TL, Million RR, Hasner RJ, McKetty HB (1979) Hodgkin’s disease stages I and II. Relationship or recurrence to size of disease, radiation dose, and number of sites involved. Cancer 43: 1101–1105Google Scholar
  792. Theml H, Bartels H, Brittinger G, Common H, Dühmke E, Fülle HH, Gunzer U, Gyenes T, Heinz R, König E, Meusers P, Paukstat M, Pralle H, Lennert K, Feller AC, Köpcke W, Thieme C, Musshoff K, Stacher A, Herrmann F, Burger-Schüler A, Gremmel H, Gerhartz H, Koeppen KM, Huhn D, Schoengen A, Nowicki L, Pees HW, Wannenmacher M, Schmidt M, Michlmayr G, Zettel R, Rühl U (für Kieler Lymphomgruppe) (1983) Klinik, Prognose und internistische Therapie der Non-Hodgkin-Lymphome von niedrigem Malignitätsgrad. Verh Dtsch Ges Inn Med 89: 352–370Google Scholar
  793. Thiel E (1984) Biological and clinical significance of immunological cell markers in leukemia. In: Thiel E, Thierfelder S (eds) Leukemia. Recent developments in diagnosis and therapy. Recent results in cancer research, vol XCIII. Springer, Berlin Heidelberg New York, pp 102–158Google Scholar
  794. Thiele J, Ballard ACh, Georgii A (1977) Freeze-fracture of the normal and pathological megakaryoblastic-granulocytic myelosis. Virchows Arch B 23: 33–51Google Scholar
  795. Thiele J, Ballard ACh, Georgii, Vykoupil KF (1977) Chronic megakaryocytic-granulocytic myelosis — An electron microscopic study. I. Megakaryocytes and thrombocytes. Virchows Arch A 373: 181–211Google Scholar
  796. Thiele J, Ballard ACh, Georgii A, Vykoupil KF (1977) Chronic megakaryocytic-granulocytic myelosis — An electron microscopic study including freeze-fracture. II Granulocytes, erythrocytes, plasma cells and myeloid stroma. Virchows Arch A 375: 129–146Google Scholar
  797. Thomas ED, Buckner CD, Storb R (1976) Total body irradiation in preparation for marrow engraftment. Transplant Proc 4: 591–593Google Scholar
  798. Thomas ED, Buckner CD, Banaji M, Cliff RA, Feser A, Flournoy W, Goodell BW, Hickman RO, Lerner KG, Neiman PE, Sale GE, Sanders JE, Singard J, Stevens M, Storb R, WeidenGoogle Scholar
  799. PL (1977) One hundred patients with acute leukemia treated by chemotherapy, total body irradiation and allogeneic marrow transplantation. Blood 49: 511–533Google Scholar
  800. Thomas ED, Clift RA, Hersman J, Sanders JE, Buckner CD, Fefer A, McCuffin R, Smith JW, Storb R (1982) Marrow transplantation for acute nonlymphoblastic leukemia in first remission using fractionated or single-dose irradiation. Int J Radiat Oncol Biol Phys 8: 817821Google Scholar
  801. Thyss A, Milano G, Caldani C, Lesbats G, Schneider M, Lalanne CM (1982) Polyamines as biological markers in malignant lymphomas. Eur J Cancer Clin Oncol 18: 611–616PubMedCrossRefGoogle Scholar
  802. Tobias JS, Richards JDM, Blackman GM, Joannides T, Trask CWL, Nathan JI (1985) Hemibody irradiation in multiple myeloma. Radiother Oncol 3: 11–16PubMedCrossRefGoogle Scholar
  803. Todd IDH (1965) Treatment of solitary plasmacytoma. Klin Radiol 16: 385–399Google Scholar
  804. Todd IDH (in collaboration with D. Crowther and PM Wilkinson) (1985) Malignant lymphomas (including myeloproliferative disorders) In: Easson EC, Pointon RCS (eds) The radiotherapy of malignant disease. Springer, Berlin Heidelberg New York, pp 347–380Google Scholar
  805. Toetterman KJ, Pesonen E, Siltanen P (1983) Radiation-related chronic heart disease. Chest 83: 875–878CrossRefGoogle Scholar
  806. Torti FL, Portlock CS, Rosenberg SA, Kaplan HS (1981) Extralymphatic Hodgkin’s disease. Prognosis and response to therapy. Am J Med 70: 487–492Google Scholar
  807. Travis EL (1983) The sequence of histological changes in mouse lungs after single dose of X-rays. Int J Radiat Oncol Biol Phys 9: 691–699PubMedCrossRefGoogle Scholar
  808. Trott KR, Holler E, Kolb HJ (1981) Strahlenbiologische Überlegungen zur Weiterentwicklung der Ganzkörperbestrahlung bei der Behandlung akuter Leukämien mit anschließender Knochenmarktransplantation. Strahlenther 157: 537–541Google Scholar
  809. Trott KR, Kummermehr J (1985) What is known about tumour proliferation rates to choose between accelerated fractionation on hyperfractionation. Radiother Oncol 3: 1–9PubMedCrossRefGoogle Scholar
  810. Trousseau (1857) Gaz des hôspitaux, S.577. 1868 übersetzt von Colmann und Niemeyer. Med Klinik des Hotel Dieu in Paris, Bd 3, S 2Google Scholar
  811. Tubiana M (Veranst) (1966) La radiotherapie de la maladie de Hodgkin. Symposium international organisé a Paris, fevrier 1965. J Radiologie [Suppl] 47: 1–176Google Scholar
  812. Tubiana M, Attie E, Flamant R, Gerard-Marchant R, Hayat M (1971) Prognostic factors in 454 cases of Hodgkin’s disease. Cancer Res 31: 1801–1810PubMedGoogle Scholar
  813. Tubiana M, Hayat M, Henry-Amar M, Breur K, Van der Werf-Messing B, Burgers M (1981) Five year results of the E.O.R.T.C. randomized study of splenectomy and splen irradiation in clinical stages I and II of Hodgkin’s disease. Eur J Cancer 17: 355–363Google Scholar
  814. Tubiana M, Henry-Amar M, Burgers M, Van der Werf-Messing B, Hayat M (1984 a) Prognostic significance of erythrocyte sedimentation rate in clinical stages I—II of Hodgkin’s disease. J Clin Oncol 2: 194–200Google Scholar
  815. Tubiana M, Henry-Amar M, Hayat M, Burgers M, Qasim M, Somers R, Sizoo W, van der Schueren E ( 1984 b) The EORTC treatment of early stages of Hodgkin’s disease: The role of radiotherapy. Int J Radiat Oncol Biol Phys 10: 197–210Google Scholar
  816. Tubiana M, Henry-Amar M, Hayat M, Burgers M, Qasim M, Somers R, Sizoo W, van der Schueren E (1984c) Prognostic significance of the number of involved areas in the early stages of Hodgkin’s disease. Cancer 54: 885–894PubMedCrossRefGoogle Scholar
  817. Tubiana M, Henry-Amar M, van der Werf-Messing B, Henry J, Abbatucci J, Burgers M, Hayat M, Somers R, Laugier A, Carde P (1985) A multivariate analysis of prognostic factors in early stage Hodgkin’s disease for the Radiotherapy-Chemotherapy Group of EORTC. Int J Radiat Oncol Biol Phys 11: 23–30PubMedCrossRefGoogle Scholar
  818. Tulinius H (1974) Epidemiology of Hodgkin’s disease. XI Intern. Cancer Congress, Florence, October 20–26, 1974Google Scholar
  819. Unger PF, Auclerc G, Weil M, Jacquillat C (1981) Tumeurs solides apres traitement pour maladie de Hodgkin. Nouv Presse Med 10: 1463–1467PubMedGoogle Scholar
  820. Valagussa P, Santoro A, Fossati Belliani F, Franchi F, Banfi A, Bonadonna G (1982) Absence of treatment-induced second neoplasmas after ABVD in Hodgkin’s disease. Blood 59: 488–494PubMedGoogle Scholar
  821. Valagussa P, Santoro A, Fossati Belliani F, Franchi F, Banfi A, Bonadonna G (1982) Absence of treatment-induced second neoplasmas after ABVD in Hodgkin’s disease. Blood 59: 488–494PubMedGoogle Scholar
  822. Van den Berghe H (1973) The Ph-chromosome: Translocation of chromosome. 9. Lancet I1: 1030–1031CrossRefGoogle Scholar
  823. Van Dyk J (1983) Whole and partial body radiotherapy: physical considerations. In: Wright A, Boyer AL (eds) Advances in radiation therapy treatment planning. Med Phys Monogr 9: 403–426Google Scholar
  824. Van Dyk J (1985) Total and half body photon irradiation: Review of AAPM task group 29 activities and recommendations. Med Biol Eng Comp 23:589–590, Suppl 2Google Scholar
  825. Van Dyk J, Keane TJ, Kan S, Rider WD, Fryer CJH (1981) Radiation pneumonitis following large single dose irradiation: a re-evaluation based on absolute dose to lung. Int J Radiat Oncol Biol Phys 7: 461–467PubMedCrossRefGoogle Scholar
  826. Van Dyk J, Mah K, Keane TJ, Poon PY (1985) Dose response data for acute radiation induced pulmonary damage: preliminary results. Med Biol Eng Comp 23:600–601, Suppl 2Google Scholar
  827. Van Vloten WA (1982) Dutch mycosis fungoides study group. In: Goos M, Christophers E (eds) Lympho-proliferative diseases of the skin. Springer, Berlin Heidelberg New York, pp 260–265CrossRefGoogle Scholar
  828. Vann DC, Makinodan T (1969) In vitro antibody synthesis by diffusion chamber culture of spleen cells. J Immunol 102: 442–450PubMedGoogle Scholar
  829. Velentjas E, Barret A, Mc Elvain et al. (1980) Mediastinal involvement in early stage Hodgkin’s disease. Eur J Cancer 16: 1065–1068PubMedGoogle Scholar
  830. Venditti JM, Goldin A (1964) Chemotherapy of advanced mouse leukemia L 1210: comparison of methotrexated alone and in sequential therapy. Cancer Res 24: 1457–1460PubMedGoogle Scholar
  831. Veronesi U, Musumeci R, Pizzetti F, Gennari L, Bonadonna G (1974) The value of staging laparotomy in non-Hodgkin’s lymphomas. Cancer (Philad) 33: 446–459CrossRefGoogle Scholar
  832. Vezzoni MA, Lucchini R, Giardini R, Raineri M, Murone M, Vezzoni P (1983) Lactate dehydrogenase levels in cellular extracts of human malignant lymphomas. Tumori 69: 279–282PubMedGoogle Scholar
  833. Virchow R (1845) Weisses Blut. Neue Notizen aus dem Gebiet der Natur-und Heilkunde. Froriep’s Neue Notizen 36: 151Google Scholar
  834. Virchow R (1864/1865) Die Krankhaften Geschwülste, vol 2. Hirschwald, BerlinGoogle Scholar
  835. Vogler LB, Crist WM, Bockman DE, Pearl ER, Lawton AR, Cooper MD (1978) Pre-B-cell leukemia. A new phenotype of childhood lymphoblastic leukemia. N England J Med 298: 872–878Google Scholar
  836. Vykoupil KF, Thiele J, Stangel W, Krmpotic E, Georgii A (1980) Polycythemia vera. II. Transgression towards leukemia with special emphasis on histological differential diagnosis, cytogenetics and survival. Virchows Arch A 389: 325–341Google Scholar
  837. Wagstaff J, Steward W, Jones M, Deakin D, Todd I, Wilkinson P, Scarffe JH, Harris M, Crowther D (1986) Factors affecting remission and survival in patients with advanced Hodgkin’s disease treated with MVPP. Hematological Oncology 4: 135–147PubMedCrossRefGoogle Scholar
  838. Waldenström J (1944) Incipient myelomatosis or “essential” hyperglobulinemia with fibrinogenopenia - a new syndrom? Acta Med Scand 117: 216CrossRefGoogle Scholar
  839. Wannenmacher M, Slanina J, Kuphal K, Bruggmoser G (1978) Gegenwärtiger Stand der Großfeldtechnik unter Megavoltbedingungen bei der Strahlentherapie der Hodgkinschen Erkrankung - Grundlagen, Durchführung, Nebenwirkungen. Radiologie 18: 371–387Google Scholar
  840. Wara WM, Phillips TL, Margolis LW, Smith V (1973) Radiation pneumonitis–a new approach to the derivation of time-dose factors. Cancer 32: 547–552PubMedCrossRefGoogle Scholar
  841. Watson PT, Havelda CJ, Sorosky J, Kochenour NK, Schi GS, Gray L jr (1980) Irradiation-induced constrictive pericarditis requiring pericardiectomy during pregnancy. J Rep Med 24: 127–130Google Scholar
  842. Webster EW (1960) Physical considerations in the design of facilities for the uniform whole-body irradiation of man Radiology 75: 19–23Google Scholar
  843. Wehinger H, Slanina J, Jacobi H, Musshoff K, Dietz V, Sauer M, Dilger M (1974) Prophylactic central nervous system therapy with cranial irradiation and intrathecal methotrexate in acute lymphoblastic leukaemia of childhood. Strahlenther 148: 590–598Google Scholar
  844. Weidkuhn V (1984) Befunde und Behandlungsergebnisse des Morbus Hodgkin. Inauguralal dissertation Med. Fakultät Freiburg/Br.Google Scholar
  845. Weiss A (1985) Die zunehmende Bedeutung der Sonographie für die Erfassung von Organma- nifestationen maligner Lymphome. Deutsch-Österreichische Hämatologentagung, WienGoogle Scholar
  846. Werf-Messing B van der (1968) Reticulum cell sarcoma and lymphosarcoma. A retrospective study of potential survival in loco-regional disease. Eur J Cancer 4: 549–557PubMedGoogle Scholar
  847. Weshler Z, Krasnokuki D, Peshin Y, Biran S (1978) Thyroid carcinoma induced by irradiation for Hodgkin’s disease. Report of a case. Acta Radiol Oncol Radiat Phys Biol 17: 383–386Google Scholar
  848. Westling P (1965) Studies on the prognosis in Hodgkin’s disease. Acta Radiol ( Stockh ), Suppl 245Google Scholar
  849. Wintrobe MM (1974) Clinical hematology. Lea & Febiger, PhiladelphiaGoogle Scholar
  850. Wintrobe MM, Lee GR, Boggs DR, Bithell TC, Foerster J, Athens JW, Lukens JN (1981) Lymphomas other than Hodgkin’s disease. In: Clinical hematology. Lea & Febiger, Philadelphia, pp 1681–1725Google Scholar
  851. Wollner N, Exelby PR, Lieberman PH (1979) Non-Hodgkin’s lymphoma in children. A progress report on the original patients treated with the LSA2L2 protocol. Cancer 44: 1990–1999PubMedCrossRefGoogle Scholar
  852. Wollner N, Lieberman P, Exelby P, D’Angio G, Burchenal J, Fang S, Murphy ML (1975) Non-Hodgkin’s lymphoma in children: results of treatment with LSA2 L2 protocol. Br J Cancer 31, Suppl I1: 337–342Google Scholar
  853. Wollner N, Burchenal JH, Lieberman PH, Exelby P, D’Angio G, Murphy ML (1976) Non-Hodgkin’s lymphoma in children. A comparative study of two modalities of therapy. Cancer 37: 123–134Google Scholar
  854. Wollner N, Wachtel AE, Exelby PR, Centore D (1980) Improved prognosis in children with intra-abdominal non-Hodgkin’s lymphoma following LSA2 L2 protocol chemotherapy. Cancer 45: 3034–3039PubMedCrossRefGoogle Scholar
  855. Woodruff RK, Malpas JS, Paxton AM, Lister TA (1978) Plasma cell leukemia (PCL): A report on 15 patients. Blood 52: 839–845PubMedGoogle Scholar
  856. Working Formulation of Non-Hodkin’s Lymphomas for Clinical Usage. The non-Hodgkin’s lymphoma pathologic classification project: National Cancer Institute sponsored study of classifications of non-Hodgkin’s lymphomas (1982) Cancer 49:2112–2135Google Scholar
  857. Worsley A, Cuttner J, Gordon R, Reilly M, Ambinder EP, Conjalka M (1982) Therapeutic leukapheresis in a patient with hairy cell leukemia presenting with a white cell count greater than 5&/µl. Transfusion 22: 308–310PubMedCrossRefGoogle Scholar
  858. Yahahom J, Voss R, Leizerowitz R, Fuks Z, Polliak A (1983) Secondary leukemia following treatment of Hodgkin’s disease: ultrastructural and cytogenetic data in two cases with a review of the literature. Am J Clin Pathol 80: 231–236Google Scholar
  859. Young RC, Chabner BA, Canellos GR, Schein PS, DeVita VT (1973) Maintenance chemotherapy for advanced Hodgkin’s disease in remission. Lancet I: 1339–1343Google Scholar
  860. Young RC, Canellos GP, Chabner BA, DeVita VT (1975) Patterns of relapse after complete remission in Hodgkin’s disease treated with MOPP chemotherapy (Abstr) Proc Am Soc Clin Oncol 16: 249Google Scholar
  861. Young RC, Canellos GP, Chabner BA, Hubbard SM, DeVita VT Jr (1978) Patterns of relapse in advanced Hodgkin’s disease treated with combination chemotherapy. Cancer 42: 10011007Google Scholar
  862. Young RC, Howser DM, Anderson T, Fisher RI, Jaffe E, DeVita VT Jr (1979) Central nervous system complications of non-Hodgkin’s lymphoma. The potential role for prophylactic therapy. Am J Med 66: 435–443Google Scholar
  863. Zagars G, Rubin P (1981) The role of radiation therapy in malignant lymphomas including Hodgkin’s disease. In: Bennett JM (ed) Lymphomas. I. Nijhoff, The Hague Boston London, pp 235–341CrossRefGoogle Scholar
  864. Ziegler K (1911) Die Hodgkin’sche Krankheit. Fischer, JenaGoogle Scholar
  865. Zwaan FE (1979) The role of total body irradiation in preparation for bone marrow transplantation in acute leukemia. A review. Pathol Biol 27: 345–347PubMedGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • K. Musshoff
  • H. Schmitz
  • H. Stein
  • U. Quast

There are no affiliations available

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