Infections in Children with Malignant Disease
The immunosuppressed child with cancer is constantly at risk for infectious disease. The extent of susceptibility is dependent upon the integrity of the various components of the immune system and the virulence and number of microbes to which the individual is exposed. The type and stage of the malignancy, extent of anticancer and antimicrobial therapy, frequency of exposure to infectious agents, duration of hospitalization and nutritional status of the host determine the risk for infection.
KeywordsSystemic Fungal Infection Streptococcus Viridans Granulocyte Transfusion Adenine Arabinoside Ecthyma Gangrenosum
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- 3.Friedman LE, Brown AE, Miller DR, Armstrong D (1984) Staphylococcus epidermidis septicemia in children with leukemia and lymphoma. Am J Dis Child 136: 715Google Scholar
- 10.Whitley R, Hilty M, Haynes R et al (1981) Vidarabine (vira-A) therapy of chickenpox in immunosuppressed children (abstract 868). Twenty- first international conference on antimicrobial agents and chemotherapy, Chicago, November, 1981Google Scholar
- 18.Valdiviesa M, Cabanillas F, Keating M, Barkley HT, Murphy WK, Burgess MA, Frazier H, Chen T, Bodey GP (1984) Effects of intensive induction chemotherapy for extensive — disease small cell bronchogenic carcinoma in protected environment — prophylactic antibiotic units. Am J Med 76: 405CrossRefGoogle Scholar