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Squamous Cell Carcinoma, Nasal Mucosa, Rat

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Respiratory System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Clinically, squamous cell carcinomas, as well as all other malignant neoplasms of the nasal cavity, are invasive tumors that protrude dorsally or laterally from the nasal cavity (Fig. 84). Frequently, the epidermis overlying the tumor is ulcerated and necrotic. Often, during the early stages of tumor growth, a unilateral nasoocular discharge is observed; this can be associated with tumor growth and interference with nasolacrimal drainage. Once the tumor has penetrated the nasal or maxillary bones, its growth is rapid. Moribund rats exhibit marked dyspnea and emaciation.

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Authors
  1. William D. Kerns
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Editors and Affiliations

  1. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, 01772, Southborough, MA, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) & Ronald Duncan Hunt D.V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology, Emeritus) &  (Professor of Comparative Pathology)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, Federal Republic of Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1985 Springer-Verlag Berlin Heidelberg

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Kerns, W.D. (1985). Squamous Cell Carcinoma, Nasal Mucosa, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Respiratory System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96846-4_7

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  • DOI: https://doi.org/10.1007/978-3-642-96846-4_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-96848-8

  • Online ISBN: 978-3-642-96846-4

  • eBook Packages: Springer Book Archive

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