Squamous Cell Carcinoma, Nasal Mucosa, Rat
Clinically, squamous cell carcinomas, as well as all other malignant neoplasms of the nasal cavity, are invasive tumors that protrude dorsally or laterally from the nasal cavity (Fig. 84). Frequently, the epidermis overlying the tumor is ulcerated and necrotic. Often, during the early stages of tumor growth, a unilateral nasoocular discharge is observed; this can be associated with tumor growth and interference with nasolacrimal drainage. Once the tumor has penetrated the nasal or maxillary bones, its growth is rapid. Moribund rats exhibit marked dyspnea and emaciation.
KeywordsFormaldehyde Lignin Luminal Pyrene Neuroblastoma
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