Alveolar Lipoproteinosis, Rat

Abstract

The pleural surface of affected rats is quite typical. In initial stages small, white to grayish, round, elevated foci appear on lung surfaces (Fig. 212). If the involvement is minor, these foci can easily be overlooked. If the involvement is more extensive, a tendency toward confluence can be observed. The foci appear to expand and become confluent with greater age. In our test series, two different types of additional changes were observed. In one of these, the lesions were nodular, suggesting tumor (Fig.213). The grayish white foci differed in size and were well separated from each other. In confluent lesions (the second type), single foci were not recognizable (Fig. 214); the affected lung surface was gray and slightly elevated in relief.