Radiation-Induced Squamous Cell Carcinoma, Lung of Rodents
Squamous cell carcinomas usually appear as spherical or multilobulated nodules with circumscribed borders (Fig. 165). They may be solitary or, on occasion, several may be found in one lung. Solitary nodules may achieve a relatively large size and occupy much of the thorax. There is no predilection for any one lung lobe. They are found in the parenchyma and are rarely oriented around major airways.
KeywordsAdenocarcinoma Adenoma Uranium Polycyclic Aromatic Hydrocarbon Radionuclide
Unable to display preview. Download preview PDF.
- Annals of the ICRP (1980) Biological effects of inhaled radionuclides. Pergamon, New YorkGoogle Scholar
- Kennedy AR, Little JB (1978) Radiation carcinogenesis in the respiratory tract. In: Harris CC (ed) Pathogenesis and therapy of lung cancer. Dekker, New YorkGoogle Scholar
- La Fuma J, Nenot JC, Morin M, Masse R, Metivier H, Nolibe D, Skupinski W (1974) Respiratory carcinogenesis in rats after inhalation of radioactive aerosols of actinides and lanthanides in various physiochemical forms. In: Karbe E, Park JF (eds) Experimental lung cancer: carcinogenesis and bioassays. Springer, Berlin Heidelberg New YorkGoogle Scholar
- Masse R (1980) Histogenesis of lung tumors induced in rats by inhalation of alpha emitters: an overview. In: Sanders CL, Cross FT, Dagle GE, Mahaffey JA (eds) Pulmonary toxicology of respirable particles. DOE symposium series, 53 CONF-791002. National Technical Information Service, SpringfieldGoogle Scholar
- Sanders CL, Dagle GE (1974) Studies of pulmonary carcinogenesis in rodents following inhalation of transuranic compounds. In: Karbe E, Park JF (eds) Experimental lung cancer: carcinogenesis and bioassays. Springer, Berlin Heidelberg New YorkGoogle Scholar