Skip to main content

Pancreatic Islet-Cell Hyperplasia, Golden Hamster

  • Chapter
Book cover Endocrine System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Enlarged islets of Langerhans may be visible grossly as clear, hyperemic, or hemorrhagic nod­ules 1–2 mm in diameter, embedded in opaque, gray acinar tissue.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Carpenter AM, Gerritsen GC, Dulin WE, Lazarow A (1967) Islet and beta cell volumes in diabetic Chinese hamsters and their nondiabetic siblings. Diabetologia 3: 92–96

    Google Scholar 

  • Conn JW (1958) Prediabetic state in man: definition, interpretation and implications. Diabetes 7: 347–357

    PubMed  CAS  Google Scholar 

  • Fajans SS, Floyd JC, Thiffault CA, Knopf RF, Harrison TS, Conn JW (1968) Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man. Ann NY Acad Sci 150: 261–280

    Article  PubMed  CAS  Google Scholar 

  • Frenkel JK (1960) Pancreatic islet cell hyperplasia in hamsters treated with cortisone and chlorothiazide (Diuril). Fed Proc 19: 160

    Google Scholar 

  • Frenkel JK (1972) Dissecting aneurysms of the aorta, and pancreatic islet cell hyperplasia with diabetes in corticosteroidand chlorothiazide-treated hamsters. Prog Exp Tumor Res 16: 300–324

    PubMed  CAS  Google Scholar 

  • Goldner MG, Zarowitz H, Akgun S (1960) Hyperglycemia and glycosuria due to thiazide derivatives administered in diabetes mellitus. N Engl J Med 262: 403–405

    Article  PubMed  CAS  Google Scholar 

  • Hausberger FX, Ramsay AJ (1953) Steroid diabetes in guinea pigs: Effects of cortisone administration on blood and urinary glucose, nitrogen excretion, fat deposition, and islets of Langerhans. Endocrinology 53: 423–435

    Google Scholar 

  • Kahn CR, Goldfine ID, Neville DM Jr, DeMeyts P (1978) Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone. Endocrinology 103: 1054–1066

    Article  PubMed  CAS  Google Scholar 

  • Lazarus SS, Bencosme SA (1955) Alterations of pancreas during cortisone diabetes in rabbit. Proc Soc Exp Biol Med 89: 114–118

    PubMed  CAS  Google Scholar 

  • Meier H, Yerganian GA (1959) Spontaneous hereditary diabetes mellitus in Chinese hamster (Cricetulus griseus). I. Pathological findings. Proc Soc Exp Biol Med 100: 810–815

    Google Scholar 

  • Potter EL, Seckel HPG, Stryker WA (1941) Hypertrophy and hyperplasia of the islets of Langerhans of the fetus and of the newborn infant. Arch Pathol 31: 467–482

    Google Scholar 

  • Runyan JW Jr (1962) Influence of thiazide diuretics on carbohydrate metabolism in patients with mild diabetes. N Engl J Med 267: 541–543

    Article  PubMed  CAS  Google Scholar 

  • Staquet MJ, Nabwangu J, Wolff F (1965) The effect of thiazides on the blood sugar of alloxanized and suballoxanized rats. Metabolism 14: 1307–1310

    Article  PubMed  CAS  Google Scholar 

  • Tabachnick IIA, Gulbenkian A (1968) Mechanism of diazoxide hyperglycemia in animals. Ann NY Acad Sci 150: 204–218

    Article  PubMed  CAS  Google Scholar 

  • Tornita T, Visser P, Friesen S, Doull V (to be published) Cortisone induced islet cell hyperplasia in hamsters.

    Google Scholar 

  • Visser PA, Pierce GE, Tornita T, Friesen SR (1979) Stimulation of pancreatic islet hypertrophy and beta cell hyperplasia in Syrian hamsters. Surg Forum 30: 310–311

    PubMed  CAS  Google Scholar 

  • Volk BW, Lazarus SS (1963) Ultramicroscopic studies of rabbit pancreas during cortisone treatment. Diabetes 12: 162–173

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Frenkel, J.K. (1983). Pancreatic Islet-Cell Hyperplasia, Golden Hamster. In: Jones, T.C., Mohr, U., Hunt, R.D., Capen, C.C. (eds) Endocrine System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96720-7_62

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-96720-7_62

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-96722-1

  • Online ISBN: 978-3-642-96720-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics