Abstract
Enlarged islets of Langerhans may be visible grossly as clear, hyperemic, or hemorrhagic nodules 1–2 mm in diameter, embedded in opaque, gray acinar tissue.
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References
Carpenter AM, Gerritsen GC, Dulin WE, Lazarow A (1967) Islet and beta cell volumes in diabetic Chinese hamsters and their nondiabetic siblings. Diabetologia 3: 92–96
Conn JW (1958) Prediabetic state in man: definition, interpretation and implications. Diabetes 7: 347–357
Fajans SS, Floyd JC, Thiffault CA, Knopf RF, Harrison TS, Conn JW (1968) Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man. Ann NY Acad Sci 150: 261–280
Frenkel JK (1960) Pancreatic islet cell hyperplasia in hamsters treated with cortisone and chlorothiazide (Diuril). Fed Proc 19: 160
Frenkel JK (1972) Dissecting aneurysms of the aorta, and pancreatic islet cell hyperplasia with diabetes in corticosteroidand chlorothiazide-treated hamsters. Prog Exp Tumor Res 16: 300–324
Goldner MG, Zarowitz H, Akgun S (1960) Hyperglycemia and glycosuria due to thiazide derivatives administered in diabetes mellitus. N Engl J Med 262: 403–405
Hausberger FX, Ramsay AJ (1953) Steroid diabetes in guinea pigs: Effects of cortisone administration on blood and urinary glucose, nitrogen excretion, fat deposition, and islets of Langerhans. Endocrinology 53: 423–435
Kahn CR, Goldfine ID, Neville DM Jr, DeMeyts P (1978) Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone. Endocrinology 103: 1054–1066
Lazarus SS, Bencosme SA (1955) Alterations of pancreas during cortisone diabetes in rabbit. Proc Soc Exp Biol Med 89: 114–118
Meier H, Yerganian GA (1959) Spontaneous hereditary diabetes mellitus in Chinese hamster (Cricetulus griseus). I. Pathological findings. Proc Soc Exp Biol Med 100: 810–815
Potter EL, Seckel HPG, Stryker WA (1941) Hypertrophy and hyperplasia of the islets of Langerhans of the fetus and of the newborn infant. Arch Pathol 31: 467–482
Runyan JW Jr (1962) Influence of thiazide diuretics on carbohydrate metabolism in patients with mild diabetes. N Engl J Med 267: 541–543
Staquet MJ, Nabwangu J, Wolff F (1965) The effect of thiazides on the blood sugar of alloxanized and suballoxanized rats. Metabolism 14: 1307–1310
Tabachnick IIA, Gulbenkian A (1968) Mechanism of diazoxide hyperglycemia in animals. Ann NY Acad Sci 150: 204–218
Tornita T, Visser P, Friesen S, Doull V (to be published) Cortisone induced islet cell hyperplasia in hamsters.
Visser PA, Pierce GE, Tornita T, Friesen SR (1979) Stimulation of pancreatic islet hypertrophy and beta cell hyperplasia in Syrian hamsters. Surg Forum 30: 310–311
Volk BW, Lazarus SS (1963) Ultramicroscopic studies of rabbit pancreas during cortisone treatment. Diabetes 12: 162–173
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© 1983 Springer-Verlag Berlin Heidelberg
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Frenkel, J.K. (1983). Pancreatic Islet-Cell Hyperplasia, Golden Hamster. In: Jones, T.C., Mohr, U., Hunt, R.D., Capen, C.C. (eds) Endocrine System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96720-7_62
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DOI: https://doi.org/10.1007/978-3-642-96720-7_62
Publisher Name: Springer, Berlin, Heidelberg
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