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Adenoma and Carcinoma, Pars Distalis, Rat

  • Chapter
Endocrine System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Pituitary neoplasms vary greatly in size, from single or multiple microscopic foci to large masses that replace the whole gland, markedly enlarging it up to a diameter of 20 mm and a weight of 350 mg or more (Kovacs et al. 1977; Fig. 125). The tumors are generally well defined, spherical, circumscribed, soft, friable, and smooth, but they may have an irregular nodular surface and they are not encapsulated. Either they are solid, or they contain cavernous vessels with hemorrhages and congestion (Andersson 1969). The tumors are separated from the brain, but a few tumors invade the adjacent brain and meninges. Large tumors protrude from the sella and produce compression atrophy of the adjacent brain parenchyma (Wolfe et al. 1938; Ross et al. 1970; Kovacs et al. 1977). The cut surface is light brown to dark red depending on the vascularity of the neoplasm.

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Authors
  1. William W. Carlton
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  2. Christian L. Gries
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Editor information

Editors and Affiliations

  1. New England Regional Primate Research Center, Emeritus Harvard Medical School, One Pine Hill Drive, 01772, Southborough, MA, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology) (Professor of Comparative Pathology)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, West Germany

    Ulrich Mohr

  3. New England Regional Primate Research Center, Harvard Medical School, 01772, Southborough, MA, USA

    Ronald Duncan Hunt D.V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology)

  4. Ohio State University, 43210, Columbus, OH, USA

    Charles C. Capen D.V.M., Ph.D. (Professor of Pathobiology and Endocrinology) (Professor of Pathobiology and Endocrinology)

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© 1983 Springer-Verlag Berlin Heidelberg

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Carlton, W.W., Gries, C.L. (1983). Adenoma and Carcinoma, Pars Distalis, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D., Capen, C.C. (eds) Endocrine System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96720-7_29

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  • DOI: https://doi.org/10.1007/978-3-642-96720-7_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-96722-1

  • Online ISBN: 978-3-642-96720-7

  • eBook Packages: Springer Book Archive

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