Zusammenfassung
Hemmung der DNS- und RNS-Synthese durch Erzeugung von Querverbindungen zwischen den Nukleinsäurefäden. Im Unterschied zu den anderen alkylierenden Substanzen besitzen die Nitrosoharnstoffe die besondere Eigenschaft, die Blut-Hirn-Schranke passieren zu können.
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© 1982 Springer-Verlag Berlin Heidelberg
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Fölsch, U.R., Junge, U. (1982). Zytostatika. In: Medikamentöse Therapie in der Gastroenterologie. Kliniktaschenbücher. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96689-7_35
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DOI: https://doi.org/10.1007/978-3-642-96689-7_35
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