Skip to main content

The Biochemistry of Hepatic Detoxification

  • Chapter
Artificial Liver Support

Abstract

The biochemistry of hepatic detoxification mechanisms is reviewed, and the application of the enzyme systems which are responsible for such processes in a device for extracorporeal detoxification in liver failure is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aitio A (ed) (1978) Conjugation reactions in drug biotransformation. Elsevier/North-Holland Biomedical, Amsterdam Oxford New York

    Google Scholar 

  • Arias IM, Jakoby WB (eds) (1976) Glutathione, metabolism and function. Raven New York

    Google Scholar 

  • Bonse G, Metzler M (1978) Biotransformationen organischer Fremdsubstanzen. Thieme, Stuttgart

    Google Scholar 

  • De Meio RH (1975) Sulphate activation and transfer. In: Greenber DM (ed) Metabolic pathways. Academic Press, New York, pp 287–358

    Google Scholar 

  • Dutton GJ (ed) (1966) Glucuronic acid, free and combined. Academic Press, New York

    Google Scholar 

  • Dutton GJ, Burchell B (1975) Newer aspects of glucuronidation. In: Bridges JW, Chasseaud LF (eds) Progress in drug metabolism. Wiley Interscience, London, pp 1–70

    Google Scholar 

  • Holloway CJ, Husmann-Holloway S, Brunner G (1979) Enzymatic methylation of alkane thiols. Enzyme 24:307–312

    PubMed  CAS  Google Scholar 

  • Holloway CJ, Husmann-Holloway S, Brunner G (1980) New method for the quantitative assay of the enzymatic hydrolysis of UDPglucuronic acid using analytical capillary isotachophoresis, J Chromatogr 188:235–245

    Article  CAS  Google Scholar 

  • Williams RT (1959) Detoxication mechanisms. Chapman & Hall, London

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Springer Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Holloway, C.J. (1981). The Biochemistry of Hepatic Detoxification. In: Brunner, G., Schmidt, F.W. (eds) Artificial Liver Support. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96629-3_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-96629-3_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-96631-6

  • Online ISBN: 978-3-642-96629-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics