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Kombination der internistischen Tumortherapie mit Chirurgie und Strahlentherapie

  • R. Hünig
  • W. Müller
  • G. A. Nagel

Zusammenfassung

Auf den Therapiegrundsatz

Tumor lokalisiert — Therapie lokalisiert

Tumor generalisiert — Therapie systemisch

wird an mehreren Stellen dieses Buches nachdrücklich hingewiesen. Diesem Grundsatz nun aber dem Buchstaben nach zu handeln, hieße auf wesentliche Fortschritte der heutigen differenzierten Tumortherapie verzichten. Weil maligne Tumoren mit medikamentöser Behandlung allein nur ausnahmsweise heilbar sind, sollte stets nach wirksamen Supplementärmaßnahmen Ausschau gehalten werden; die größten Erfolge der Systemtherapie werden nicht mit ihr allein, sondern in ihrer Kombination mit chirurgischen und strahlentherapeutischen Maßnahmen erzielt. Eine gute Onkologie ist heute interdisziplinär organisiert.

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Literatur

  1. ADAMS, G.E., FOWLER, J.F., DISCHE, S., THOMLINSON, R.H.: Hypoxie cell sensitisers in radiotherapy. Lancet 1976I, 186–188CrossRefGoogle Scholar
  2. ANDREWS, J.R.: Combined cancer radiotherapy and chemotherapy: The relevance of cell population kinetics and pharmacodynamics. Cancer Chemother. Rep. Part 1, 53, 313 (1969)PubMedGoogle Scholar
  3. BRUNNER, K.W., MARTHALER, T., MÜLLER, W.: Unfavourable effects of long term adjuvant chemotherapy with endoxan in radically operated bronchogenic carcinoma. Europ. J. Cancer 7, 285 (1971)CrossRefGoogle Scholar
  4. CAVALIERE, R.: Regional hyperthermia by perfusion. In: Internations symposium on cancer therapy by hyperthermia and radiation. Washington, D.C., April 28–30, 1975Google Scholar
  5. CAVALIERE, R., CIOCATTO, E.C. et. al.: Selective heat sensitivity of cancer cells. Cancer 20, 1351–1381 (1967)PubMedCrossRefGoogle Scholar
  6. CHURCHILL-DAVIDSON, I.: Hyperbaric oxygen and radiotherapy: Clinical experiences. In: Frontiers of radiation therapy and oncology, vol. 1. VAETH, J.M. (ed.), p. 156. Basel-New York: Karger 1968Google Scholar
  7. DENEKAMP, J., HARRIS, S.R.: Tests of two electron-affinic radiosensitizers in vivo using regrowth of an experimental carcinoma. Radiat. Res. 61, 191–203 (1975)PubMedCrossRefGoogle Scholar
  8. DUNCAN, W., NIAS, A.H.W.: Clinical radiobiology. Edinburgh-London-New York: Churchill Livingstone 1977Google Scholar
  9. ELKIND, M.M., KANO, E., SAKAMOTO, K.: Drug-radiation damage interaction and its relevance to radiosensitization in mammalian cells. In: Radiation protection and sensitization. MOROSON, H.L., QUINTILIANI, M. (eds.), p. 195. London: Taylor & Francis 1970Google Scholar
  10. FARBER, S.: Clinical and biological studies with actinomycins. In: Ciba foundation symposium on amino acids and peptides with antimetabolic activity. WOLSTENHOLME, G.E.W., O’CONNOR, C.M. (eds.), p. 138. Boston: Little, Brown & Co. 1958Google Scholar
  11. FLETCHER, G.H.: Textbook of radiotherapy. 2nd Ed. Philadelphia: Lea & Febiger 1973Google Scholar
  12. GRAY, A.J., DISCHE, S., ADAMS, G.E., FLOCKHART, I.R., FOSTER, J.L.: Clinical testing of the radiosensitiser Ro-07-0582. I. Dose tolerance, serum and tumour concentrations. Clin. Radiol. 27, 151–157 (1976)PubMedCrossRefGoogle Scholar
  13. HALL, R.R., SCHADE, R.O.K., SWINNEY, J.: Effects of hyperthermia on bladder cancer. Brit. med. J. 1974II, 593–594CrossRefGoogle Scholar
  14. HARBERS, E.: Experimentelle Untersuchungen über das Zusammenwirken von Chemotherapeutika und Röntgenstrahlen. Strahlentherapie Sonderbd. 57, Krebsforschung und Krebsbekämpfung 5, 182 (1964)Google Scholar
  15. HASHINO, T., SANO, K.: Radiosensitization of malignant brain tumours with bromourdine (thymidine analogue). Acta radiol. Ther. 8, 15–26 (1969)Google Scholar
  16. KARRER, K.: Importance of dose schedules in adjuvant chemotherapy. Cancer Chemother. Rep. Part 1, 56, 35 (1972)Google Scholar
  17. KRAMER, S. (chairman): Research plan for radiation oncology. Cancer Suppl. 37 (1976)Google Scholar
  18. LETT, J.T., ADLER, H. (eds.): Advances in radiation biology, vol. 6. New York-San Francisco-London: Academic Press 1976Google Scholar
  19. PETTIGREW, R.T.: Cancer therapy by whole body heating. In: International symposium on cancer therapy by hyperthermia and radiation. Washington, D.C., April 28–30, 1975Google Scholar
  20. ROSSI-FANELLI, A., CAVALIERE, R., MONDOVI, B., MORICCA, G. (eds.): Selective heat sensitivity of cancer cells. In: Recent results in cancer research, vol. 59. Berlin-Heidelberg-New York: Springer 1977Google Scholar
  21. RUBIN, PH., GREEN, J.: Solitary metastases. Springfield/Ill.: Thomas 1968Google Scholar
  22. THOMLINSON, R.H.: Changes in oxygenation in tumours in relation to irradiation. In: Frontiers of radiation therapy and oncology, vol. 3. VAETH, J.M. (ed.), p. 109. Basel-New York: Karger 1968Google Scholar
  23. TURNBULL, A.D., POOL, J.L., ARTHUR, K., GOLBEY, R.B.: The role of radiotherapy and chemotherapy in the surgical management of pulmonary metastases. Am. J. Roentgenol. 114, 99 (1972)Google Scholar
  24. VAETH, J.M. (ed.): Frontiers of radiation therapy and oncology, vol. 4: The interrelationship of chemotherapeutic agents and radiation therapy in the treatment of cancer. Basel-New York: Karger 1969Google Scholar
  25. VERMUND, H.: Enhancement of radiation effects by chemotherapy. Acta radiol. (Stockh.), Suppl. 311 (1971)Google Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1979

Authors and Affiliations

  • R. Hünig
  • W. Müller
  • G. A. Nagel

There are no affiliations available

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