Frühbehandlung der leichten Hypertonie

  • Klaus O. Stumpe

Zusammenfassung

Geringgradige Blutdruckerhöhungen werden relativ häufig und in allen Altersgruppen beobachtet. Eine einheitlich anerkannte Definition der sog. leichten Hypertension fehlt, ebenso wie die Beantwortung der Frage, bis zu welchem Blutdruckwert eine Behandlung nicht erforderlich ist. Theoretisch müßte die Entscheidung zur Therapie durch die Höhe desjenigen Blutdruckwertes bestimmt werden, der das Risiko einer sog. Exzeßmorbidität und -mortahtät zu einem zukünftigen Zeitpunkt in sich birgt.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Ames RP, Hih P (1976) Increase in serum lipids during treatment of hypertension with chlorthalidone. Lancet 1:721–723PubMedCrossRefGoogle Scholar
  2. 2.
    Bagdade JD, Albers JJ (1977) High densitiy lipoproteins with chronic hemodialysis and renal transplants. N Engl J Med 296:1436–1439PubMedCrossRefGoogle Scholar
  3. 3.
    Baumgartner G, Glück Z, Weidmann P, Peheim E, Flammer J (1978) Increased ratio between serum beta- and alpha-lipoproteins during diuretic therapy. Kidney Int. 14:480–486Google Scholar
  4. 4.
    Davidson C, Thadani U, Singleton W, Taylor SH (1976) Comparison of beta-blocking drugs during chronic treatment. Br Med J III: 7–9CrossRefGoogle Scholar
  5. 5.
    Department of Pubhc Health, State of California (1968) Alameda County blood pressure study, BerkeleyGoogle Scholar
  6. 6.
    Dyer AR, Stamler J, Shekelle R, Schoenberger JA, Farinaro E (1977) Hypertension in the elderly. Med Clin North Am 61:513–529PubMedGoogle Scholar
  7. 7.
    Freis ED (1976) Salt, volume and the prevention of hypertension. Circulation 53:589–595PubMedGoogle Scholar
  8. 8.
    Gordon T, Castelh WP, Hjortland MC, Kannel WB, Dawber TR (1977) High density lipoprotein as protective factor against coronary heart disease. The Framingham study. Am J Med 62:707–714PubMedCrossRefGoogle Scholar
  9. 9.
    Hansson L, Werkö H (1977) Beta-adrenergic blockade in hypertension. Am Heart J 93:394–404PubMedCrossRefGoogle Scholar
  10. 10.
    Julius S (1977) Borderline hypertension. An overview. Med Clin North Am 61:495–510PubMedGoogle Scholar
  11. 11.
    Kannel WB, Schwartz MJ, McNamara PM (1969) Blood pressure and risk of coronary heart disease: The Framingham study. Dis Chest 56: 43–52PubMedCrossRefGoogle Scholar
  12. 12.
    Lambert DMD (1976) Effect of propranolol in patients with angina. Postgrad Med J (Suppl 4) 52:57–60Google Scholar
  13. 13.
    Levy RL, White PD, Stroud WD (1945) Transient tachycardia: Prognostic significance alone and in association with transient hypertension. JAMA 129:585–588CrossRefGoogle Scholar
  14. 14.
    MacKenzie LF, Shepherd P (1937) The significance of past hypertension in applicants later presenting normal average blood pressures. Proc Assoc Life Insur Med Dir Am 24:157–178Google Scholar
  15. 15.
    Mathisen HS, Loken H, Brox D (1965) The prognosis in essential hypertension. Scand J Clin Lab Invest (Suppl 84) 17:257–261Google Scholar
  16. 16.
    Metropolitan Life Insurance Company (1961) Blood pressure: insurance experience and its im- phcations. Metropohtan Life Insurance Co., New YorkGoogle Scholar
  17. 17.
    Morgan T, Gillies A. Morgan G, Adam W, Wilson M, Carney S (1978) Hypertension treated by sah restriction. Lancet 1:227–230PubMedCrossRefGoogle Scholar
  18. 18.
    National high blood pressure education program (1973) Report of Task Force 1-Data Base. DHEW Pubhcation no (NIH) 74:593Google Scholar
  19. 19.
    Overiack A, Stumpe KO (1978) Antihypertensiver Effekt einer fixen Beta-Rezeptorenblocker- Diuretikum-Kombination bei täglich einmaliger Applikation. Med Weh 29:1517–1520Google Scholar
  20. 20.
    Priddle W, Liu S, Breithaupt D (1968) Amelioration of high blood pressure in the elderly. J Am Geriatr Soc, 16:887–892PubMedGoogle Scholar
  21. 21.
    Reisin E, Abei R, Modan M, Silverberg DS, Eha- hou H, Modan B (1978) Effect of weight loss without salt restriction on the reduction of blood pressure in overweight hypertensive patients. N Engl J Med 298:1–6PubMedCrossRefGoogle Scholar
  22. 22.
    Shanks RG (1976) The properties of beta-adre- noceptor antagonists. Postgrad Med J 52:14–20PubMedCrossRefGoogle Scholar
  23. 23.
    Stamler J, Berkson DM, Dyer A, Lepper MH, Lindberg HA (1975) Relationship of multiple variables to blood pressure-findings from four Chicago epidemiological studies. In: Paul O (ed) Epidemiology and control of hypertension. Symposia Specialists, Stratton Intercontinental, New York, p 307Google Scholar
  24. 24.
    Stamler J, Lindberg HA, Berkson DM (1958) Epidemiological analysis of hypertension and hypertensive disease in the labor force of a Chicago utility company. Proc Coun High Blood Press Res 7:23–52Google Scholar
  25. 25.
    Stewart IMG (1976) Compared incidence of first myocardial infarction in hypertensive patients under treatment containing propranolol or excluding beta-receptor blockade. Clin Sci Mol Med 51:509s-511sGoogle Scholar
  26. 26.
    Stumpe KO, Kolloch RE (1977) Beta-blocking agents in the treatment of hypertension. Compr Ther 3:55–65PubMedGoogle Scholar
  27. 27.
    Stumpe KO, Kolloch RE, Vetter H, Gramann W, Krück F (1976) Acute and long-term studies of the mechanism of action of beta-blocking drugs in lowering blood pressure. Am J Med 60:853–865PubMedCrossRefGoogle Scholar
  28. 28.
    Thomas CB, Ross DC, Higgenbottom CQ (1964) Precursors of hypertension and coronary disease among healthy medical students. Discriminant function analysis II using parental history as the criterion. Bull Johns Hopkins Hosp 115:245PubMedGoogle Scholar
  29. 29.
    Veterans Administration Cooperative Study Group on Antihypertensive Agents (1970) Effects of treatment on morbidity in hypertension. 11: Results in patients with diastolic blood pressures averaging 90 through 114 mm Hg. JAMA 213:1143–1152CrossRefGoogle Scholar
  30. 30.
    Waal-Manning HJ (1976) Hypertension: Which beta-blocker? Drugs 12:412–441PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • Klaus O. Stumpe

There are no affiliations available

Personalised recommendations