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Microtubule Structures: Centrioles, Basal Bodies, Cilia, Axonemes

  • Chapter
Microtubules

Abstract

Several cell organelles assembled from MT and other proteins perform a great role in cell biology and display a high degree of complexity. The centrioles, basal bodies, cilia and flagella, have a ninefold symmetry which, with few variants, has been maintained in most species. The association of centrioles with mitosis is found in all primitive plants and in all animal cells; its disappearance in most mitoses of higher plants indicates that centrioles are by no means indispensable for cell division, and that their relation with the spindle MT may be mainly a convenient way for the cell to assure their continuity. Centrioles and basal bodies are closely related and similar in their basic structure: the principal function of centrioles may be to form basal bodies, cilia and flagella. However, several instances of de novo formation of centrioles in cells indicate that these structures, contrary to what was thought, have no genetic continuity. This is in contradiction to the idea [106, 144] that centrioles may have a semi-autonomous existence and could possibly represent the persistence of the symbiotic union of a primitive organism devoid of MT and a spirochete-like unicellular.

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Dustin, P. (1978). Microtubule Structures: Centrioles, Basal Bodies, Cilia, Axonemes. In: Microtubules. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96436-7_6

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