Familie der Picornaviren (Enteroviren- und Rhinoviren-Gruppe)

  • Ernest Jawetz
  • Joseph L. Melnick
  • Edward A. Adelberg

Zusammenfassung

Die Picornaviridae sind kleine, Äther-resistente Viren, die RNS als Genom besitzen. Ihre als Einzelstrang vorliegende Nucleinsäure besitzt ein Molekulargewicht von 2−2,8 × 106 und macht etwa 30% der Partikelmasse aus. Das Nucleocapsid besitzt eine kubische Symmetrie, eine Hüllmembran, essentielle Lipide und Kohlenhydrate fehlen; der Durchmesser beträgt 20–30 nm. Die Virusreifung findet im Cytoplasma der Zelle statt. Zu dieser Famiüe gehören 2 Genera: Enterovirus und Rhinovirus.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Boucher, D. W., Notkins, A. L.: Virus-induced diabetes mellitus. 1. Hyperglycemia and hypoinsulinemia in mice infected with encephalomycarditis virus. J. exp. Med. 137, 1226 (1973).PubMedCrossRefGoogle Scholar
  2. Craighead, J. F.: The role of viruses in the pathogenesis of pancreatic disease and diabetes mellitus. Progr. med. Virol, 19, 161 (1975).Google Scholar
  3. Hamory, B. H., et al.: Human responses to two decavalent rhinovirus vaccines. J. infect. Dis. 132, 623 (1975).PubMedCrossRefGoogle Scholar
  4. Hamre, D.: Rhinoviruses. Monogr. Virol, Vol 1, 1968.Google Scholar
  5. Harris, T. J. R., Brown, F.: Correlation of polypeptide composition with antigenic variation in the swine vesicular disease and coxsackie B5 viruses. Nature 258, 758 (1975).PubMedCrossRefGoogle Scholar
  6. Hierholzer, J. C., Hilliard, K. A., Fsposito, J. J.: Serosurvey for „acute hemorrhagic conjunctivitis“ virus (enterovirus 70) antibodies in the southeastern United States, whh review of the literature and some epidemiologic implications. Amer. J. Epidemiol. 102, 533 (1975).Google Scholar
  7. Lerner, A. M., Wilson. F. M.: Virus myocardiopathy. Progr. med. Virol, 15, 63 (1973).Google Scholar
  8. Lundquist, R. E., Ehrenfeld, F., Maizel, J. V., jr.: Isolation of a viral polypeptide associated with poliovirus RNA polymerase. Proc. nat. Acad. Sci. (Wash.) 71, 4773 (1974).CrossRefGoogle Scholar
  9. Melnick, J. L., Wenner, H. A.: Enteroviruses. In: Diagnostic Procedures for Viral and Rickettsial Infecdons, 4th Ed., p. 529–602. American Public Health Association 1969.Google Scholar
  10. Melnick, J. L., et al.: Picornaviridae. Intervirology 4, 303 (1974).CrossRefGoogle Scholar
  11. Miller, D. A., et al.: Human chromosome 19 carries a poliovirus receptor gene. Cell 1, 167 (1974).CrossRefGoogle Scholar
  12. Mirkovic, R. R., et al.: Enterovirus type 70: The etiologic agent of pandemic acute hemorrhagic conjunctivitis. Bull. WHO 49, 341 (1973).PubMedGoogle Scholar
  13. Ogra, P. L., Karzon, D. T.: Formation and function of poliovirus antibody in different tissues. Progr. med. Virol. 13, 156 (1971).Google Scholar
  14. Rossen, R. D., Kasel, J. A., Couch, R. B.: The secretory immune system: Its relation to respiratory viral infecdon. Progr. med. Virol. 13, 194 (1971).Google Scholar
  15. Schmidt, N. J., Magoffin, R. L., Lennette, E. H.: Association of group B coxsackieviruses with cases of pericarditis, myocarditis, or pleurodynia by demonstration of immunoglobulin M antibody. Infect. Immunol. 8, 341 (1973).Google Scholar
  16. Spector, D. M., Baltimore, D.: The molecular biology of poliovirus. Sci. Amer. 232, 25 (May 1975).PubMedCrossRefGoogle Scholar
  17. Taber, L. H., et al.: Rapid diagnosis of enterovirus meningids by immunoduorescent staining of CSF leukocytes. Intervirology 1, 127 (1973).PubMedCrossRefGoogle Scholar
  18. Wyatt, H. v.: Pohomyelitis in hypogammaglobuhnemics. J. infect. Dis. 128, 802 (1973)PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1977

Authors and Affiliations

  • Ernest Jawetz
    • 1
  • Joseph L. Melnick
    • 2
  • Edward A. Adelberg
    • 3
  1. 1.Department of MicrobiologyUniversity of California School of MedicineSan FranciscoUSA
  2. 2.Baylor University College of MedicineHoustonUSA
  3. 3.Department of MicrobiologyYale University School of MedicineNew HavenUSA

Personalised recommendations