Acne pp 58-107 | Cite as

The Dynamics of Primary Comedo Formation

  • Gerd Plewig
  • Albert M. Kligman

Abstract

Two tactics have been of inestimable value for observing anatomical changes of the evolving disease: These are (1) serial sectioning and (2) biopsying apparently uninvolved areas of acne-bearing skin. Without the latter the earliest changes would not have been seen. Without serial sections many changes would have remained concealed; one section of the same specimen may look normal while elsewhere there may be startling alterations. Asymmetry is quite characteristic of acne lesions.

Keywords

Agar Hexagonal Thymidine Acne Extractor 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1975

Authors and Affiliations

  • Gerd Plewig
    • 1
  • Albert M. Kligman
    • 2
  1. 1.Department of DermatologyUniversity of MunichMunich 2Germany
  2. 2.School of Medicine, Duhring LaboratoriesUniversity of PennsylvaniaPhiladelphiaUSA

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