Disorders of Sexual Differentiation (Intersexuality)

  • A. Prader


Strictly speaking, intersexuality signifies the presence of intersexual external genitalia, i.e. genitalia which are neither definitely male nor definitely female. In the broader sense, however, all disorders of prenatal sexual differentiation belong to intersexuality. The almost incalculable multiplicity of abnormal sexual differentiation can be divided into three major groups:
  1. 1.

    Abnormal gonadal development. This is commonly the result of an abnormal set of chromosomes which in turn frequently leads to abnormal genital development.

  2. 2.

    Abnormal genital development in the presence of normal testes and usually normal male set of chromosomes (male pseudohermaphroditism).



External Genitalia Secondary Sexual Characteristic Gonadal Dysgenesis Fetal Testis Male Pseudohermaphroditism 
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Hereditary Vulviform Perineal Hypopsadia

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Pseudohermaphroditismus femininus

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Transplacentar Virilization

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Psychosexuahty and Assignment of Sex

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Copyright information

© Springer-Verlag Berlin Heidelberg 1974

Authors and Affiliations

  • A. Prader

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