Abstract
The institution of extracorporeal circulatory support in the pediatric population has been limited due to the scarcity of suitable devices. Although the successful use of miniaturized intra-aortic balloon pumps in children has been reported occasionally (23, 34), providing intra-aortic balloon pump support in this cohort has been hampered by difficulties associated with inserting cannulas into small vessels and synchronizing the device to a rapid heart rate. Its efficacy has further been questioned in small children because of increased aortic compliance. Over the last decade circulatory support in pediatric surgery has most commonly been provided through extracorporeal membrane oxygenation (ECMO)(14, 17, 25, 36). The capability of ECMO to provide biventricular as well as respiratory support may be beneficial in maintaining circulation in children, especially those with congenital heart defects. Some recent reports have described the successful use of a centrifugal ventricular assist device (VAD) in children for cardiogenic shock after cardiac surgery (6, 15), for donor heart failure, and as a bridge to cardiac transplantation (26). However, the impossibility of mobilizing the patient, generating a pulseless flow, and the short durability of the components are critical disadvantages for long-term support with ECMO or centrifugal VADs.
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Dalton H, Siewers R, Fuhrman B, del Nido P, Tompson A, Shaver M, Dowhy M (1993) Extracorporeal membrane oxygenation for cardiac rescue in children with severe myocardial dysfunction. Crit Care Medicine Vol. 21 No 7:1020–1028
del Nido PJ, Dalton HJ, Thompson AE, Siewers RD (1992) Extracorporeal membrane oxygenation rescue in children during cardiac arrest after cardiac surgery. Circulation 86 suppl II:300–304
del Nido PJ, Armitage JM, Fricker FJ, Shaver M, Cipriani L, Dayal G, Park SC, Siewers RD (1994) Extracorporeal membrane oxygenation support as a bridge to pediatric heart transplantation. Circulation 90[part 2]: II-66–69
Delius R, Bove E, Meliones J, Custer J, Moler F, Crowly D, Amirikia A, Behrendt D, Bartlett R (1992) Use of extracorporeal life support in patients with congenital heart disease. Crit Care Med 20:1216–1222
Farrar DJ, Hill JD (1994) Recovery of major organ function in patients awaiting heart transplantation with Thoratec Ventricular Assist Device. J Heart Lung Transplant 13:1125–1132
Ferrazzi P, Glauber M, Di Domenico A, Fiocchi R, Mamprin F, Gamba A, Crupi G, Cossolini M, Parenzan L (1991) Assisted circulation for myocardial recovery after repair of congenital heart disease. Eur J Cardio-thorac Surg 5:419–424
Frazier OH, Bricker JT, Macris MP, Cooley DA (1989) Use of a left ventricular assist device as a bridge to transplantation in a pediatric patient. Tex Heart Inst J 16:46–50
Friedel N, Viazis P, Schiessler A, Warnecke H, Hennig E, Trittin A, Böttner W, Hetzer R (1992) Recovery of end-organ failure during mechanical circulatory support. Eur J Cardiothorac Surg 6: 519–523
Galantowicz ME, Stolar CJH (1991) Extracorporeal membrane oxygenation for perioperative support in pediatric heart transplantation. J Thorac Cardiovasc Surg 102: 148–152
Heiss KF, Petit B, Hirschl RB, Cilley RC, Chapman R, Barlett RH (1987) Renal Insufficiency and volume overload in neonatal ECMO managed by continuous ultrafiltration. Trans Am Soc Artif Intern Organs 23:557–560
Heney D, Brocklebank JT, Wilson N (1989) Continuous arteriovenous haemofiltration in the newlyborn with acute renal failure and congenital heart disease. Nephrol Dial Transplant 4:870–876
Hennig E, Bücherl ES (1989) The “Berlin artificial heart” system. In: D’Alessandro LC (ed) Heart Surgery, C.E.S.I., Rome, pp 167–179
Hunkeler N, Canter, Donze A, Sray T (1992) Extracorporeal life support in cyanotic congenital Heart Disease Before Cardiovascular Operation. Am J Cardiol 69:790–793
Kanter KR, Pennington DG, Weber TR, Zambie MA, Braun P, Martychenko V (1987) Extracorporeal membrane oxygenation for postoperative cardiac support in children. J Thorac Cardiovasc Surg 93:27–35
Karl TR, Sano S, Horton S, Mee RBB (1991) Centrifugal pump left heart assist in pediatric cardiac operations. J Thorac Cardiovasc Surg 102:624–630
Karl TR (1994) Extracorporeal circulatory support in infants and children. Seminars in Thorac and Cardiovasc Surg 6:154–160
Klein MD, Shaheen KW, Whittlesy GC, Pinsky WW, Arciniegas E (1990) Extracorporeal membrane oxygenation for the circulatory support after repair of congenital heart disease. J Thorac Cardiovasc Surg 100:498–505
Klein MD, Withlesey GC (1994) Extracorporeal membrane oxygenation. Pediatric Clinics of North America. Vol. 41 No 2:365–384
Loebe M, Weng Y, Hennig E, Alexi-Meskishvili V, Uhlemann F, Schiessler A, Lange PE, Kopitz M, Hetzer R (1995) Mechanische Kreislaufunterstützung bei Kindern und Jugendlichen mit pulsatilem und non-pulsatilem Fluß. Z. Herz-, Thorax-, Gefäßchirur 9:85–93
Matsuda H, Taenaka Y, Obkubo N, Ohtani M, Nishigaki K, Ohtake S, Miura T, Taenaka N, Takano H, Hirose H, Kawashima Y (1988) Use of a paracorporeal pneumatic ventricular assist device for postoperative cardiogenic shock in two children with complex cardiac lesions. Artif Organs 12:423–430
Pavie A, Muneretto C, Aupart M, Rabago G, Leger P, Tedy G, Bors V, Gandjbakhch I, Cabrol C (1991) Prognostic indices of survival in patients supported with temporary devices (TAH, VAD). International Journal of Artificial Organs 14(5): 280–285
Pennington DG, Kanter KR, McBride LR, Kaiser GC, Earner HE, Miller LW, Naunheim KS, Fiore AC, Willman V (1988) Seven years’ experience with the Pierce-Donachy ventricular assist device. J Thorac Cardiovasc Surg 96:901–911
Pollock JC, Charlton MC, Williams WG, Edmonds JF, Trusler GA (1980) Intraaortic balloon pumping in children. Ann Thorac Surg 29:522–528
Robinson TM, Kickler TS, Walker LK, Ness P, Bell W (1993) Effect of extracorporeal membrane oxygenation on platelets in newborns. Crit Care Med 21:1029–1034
Rogers AJ, Trento A, Siewers RD, Griffith BP, Hardesty RL, Pahl E, Beerman LB, Fricker FJ, Fischer DR (1989) Extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock in children. Ann Thorac Surg 47:903–906
Scheinin SA, Radovancevic B, Parnis SM, Ott DA, Ericker JT, Twobin JA, Abou-Awdi NL, Frazier OH (1994) Mechanical circulatory support in children. Eur J Cardio-thorac Surg 8:537–540
Schiessler A, Friedel N, Weng Y, Heinz U, Hummel M, Hetzer R (1994) Mechanical circulatory support and heart transplantation. ASAIO J 40:M476-M481
Schneider E, Cronin J, Van Marter L, Maller E, Truog R, Jacobson M, Kevy S (1991) A prospective analysis of cholestasis in infants supported with extracorporeal membrane oxygenation. Journal of Pediatric Gastroenterology & Nutrition 13(3):285–289
Steinhorn R, Isham-Schopf B, Smith C, Green T (1989) Hemolysis during long-term extracorporeal membrane oxygenation. J Pediatr 115:625–630
Stolar CJH, Delosh T, Bartlett RH (1993) Extracorporeal Life Support Organization Registry Report. ASAIO J 39:976–979
Suddaby E, O’Brien A (1993) ECMO in cardiac support in children. Heart Lung 22:401–407
Taenaka N, Takano H, Noda H, Kinoshita M, Tatsumi E, Yagura A, Sekii H, Sasaki E, Akutsu T (1989) Experimental evaluation and clinical application of a pediatric ventricular assist device. ASAIO Trans 35:606–608
Ungerleider R (1994) Current application of neonatal ECMO. Presented at the 14th Annual San Diego Cardiothoracic surgery symposium. San Diego, USA. P. 119–130
Veasy LG, Blalock RC, Orth JL, Boucek MM (1983) Intra-aortic balloon pumping in infants and children. Circulation 68:1095–1100
Warnecke H, Berdjis F, Hennig E, Lange P, Schmitt D, Hummel M, Hetzer R (1991) Mechanical left ventricular support as a bridge to cardiac transplantation in childhood. Eur J Cardiothorac Surg 5:330–333
Weinhous L, Canter C, Noetzel M, McAlister W, Spray TL (1989) Extracorporeal membrane oxygenation for circulatory support after repair of congenital heart defects. Ann Thorac Surg 48:206–212
Zwischenberger J, Cox C (1992) ECMO in the management of cardiac failure. ASAIO Journal 38:751–753
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© 1997 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt
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Alexi-Meskishvili, V. et al. (1997). Extracorporeal circulatory support in pediatric cardiac patients — The Berlin Experience. In: Hetzer, R., Hennig, E., Loebe, M. (eds) Mechanical Circulatory Support. Steinkopff. https://doi.org/10.1007/978-3-642-95984-4_4
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DOI: https://doi.org/10.1007/978-3-642-95984-4_4
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