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Kombination von Muskelrelaxanzien mit Opioiden, Benzodiazepinen und Lachgas

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Klinik der Muskelrelaxation

Zusammenfassung

Kombinationen von nichtdepolarisierenden Muskelrelaxanzien mit Opioiden sind in vielen klinischen Studien im Hinblick auf ihre Kreislaufwirksamkeit und Pharmakodynamik untersucht worden. Sogenannte„high dose”-Opioidnarkosen oder auch etwas geringere Opioiddosierungen unter Zusatz von Benzodiazepinen kommen wegen ihrer günstigen hämodynamischen Wirkung vor allem bei Patienten mit sehr schlechter Herzfunktion zum Einsatz. Gerade bei diesen Patienten gewährleisten die Opioide Fentanyl und Sufentanil die beste Kreislaufstabilität. Vergleicht man Kombinationen aus Fentanyl oder Sufentanil mit Pancuronium, Vecuronium oder Atracurium, so zeigen sich Unterschiede vor allem im Verhalten der Herzfrequenz nach Verabreichen der Intubationsdosis bei der Narkoseeinleitung.

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Authors and Affiliations

  1. Medizinische Hochschule Hannover, Deutschland

    Frau. Dr. H. Müller & D. Schaps

  2. Herz-und Kreislaufklinik Bevensen Anaesthesiologie, Römstedter Str. 25, D-29549, Bad Bevensen, Deutschland

    Frau. Dr. H. Müller

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  1. Frau. Dr. H. Müller
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  2. D. Schaps
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Editors and Affiliations

  1. Zentrum Anästhesiologie, Medizinischen Hochschule Hannover, Konstanty-Gutschow-Str. 8, D-30625, Hannover, Deutschland

    Erich Kirchner (o. Prof. für Anästhesiologie) (o. Prof. für Anästhesiologie)

  2. ltd. Oberarzt am Zentrum Anästhesiologie, Medizinischen Hochschule Hannover, Konstanty-Gutschow-Str. 8, D-30625, Hannover, Deutschland

    Wolfgang Seitz (apl. Professor für Anästhesiologie) (apl. Professor für Anästhesiologie)

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© 1994 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt

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Müller, H., Schaps, D. (1994). Kombination von Muskelrelaxanzien mit Opioiden, Benzodiazepinen und Lachgas. In: Kirchner, E., Seitz, W. (eds) Klinik der Muskelrelaxation. Steinkopff. https://doi.org/10.1007/978-3-642-95977-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-95977-6_5

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-95978-3

  • Online ISBN: 978-3-642-95977-6

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