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Introduction

  • Gerd Bönner
  • Karl-Heinz Rahn

Abstract

The regulation of systemic blood pressure is based on multiple central and peripheral regulatory mechanisms, among which the vasoactive hormonal systems play a not insignificant part. In the past it was particularly the hormonal systems with an active vasopressor effect such as the renin-angiotensin system, the mineralocorticoids, catecholamines and the antidiuretic hormone that attracted the greatest attention in hypertension research. For a long period an excessive importance was attached to the vasopressor hormones as the essential cause of arterial hypertension, but the importance of vasodepressor hormone systems such as the kallikrein-kinin system and the prostaglandins remained unappreciated for many years, and a deficiency of vasodepressor agents was seldom considered as a pathogenetic factor in the development of hypertension. This is the more surprising since the blood pressure-lowering action of the kallikrein-kinin system (the “F substance”) had been discovered by Frey and Kraut [74] as far back as 1926.

Keywords

Systemic Blood Pressure Seminal Fluid Pathogenetic Factor Induce Platelet Aggregation Uterine Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Gerd Bönner
    • 1
  • Karl-Heinz Rahn
    • 2
  1. 1.Medizinische Universitätsklinik IIStädtische Krankenanstalten MerheimKöln 91Germany
  2. 2.Medizinische PoliklinikUniversität MünsterMünsterGermany

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