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Benign Epilepsy of Childhood with Centro-temporal Spikes

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Genetics of the Epilepsies

Abstract

Benign epilepsy in childhood with centro-temporal EEG spikes, also known as benign rolandic epilepsy, is an epileptic syndrome in which the EEG changes are part of the definition. A series of investigations [1–5, 8, 11–13) have shown that the main features are:

  1. 1.

    Partial seizures with symtoms mainly from the orofacial regions. The seizures may become secondarily generalized.

  2. 2.

    The EEG spikes can often be recorded from large areas of the hemisphere, but have a centro-temporal maximum.

  3. 3.

    Both seizures and EEG changes are related to the level of wakefulness. The seizures often occur shortly after the child has gone to sleep and the spikes increase in frequency during drowsiness and sleep. Sometimes they appear during sleep only.

  4. 4.

    The syndrome is uncommon before 3 years of age and has a maximum incidence between 5 and 10 years. The prognosis is good: In most cases the seizures disappear at puberty. The seizures are, with few exceptions, easily controlled with medication. The syndrome has not been observed in adults.

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References

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© 1989 Springer-Verlag Berlin Heidelberg

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Blom, S., Heijbel, J. (1989). Benign Epilepsy of Childhood with Centro-temporal Spikes. In: Beck-Mannagetta, G., Anderson, V.E., Doose, H., Janz, D. (eds) Genetics of the Epilepsies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95553-2_10

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  • DOI: https://doi.org/10.1007/978-3-642-95553-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-95555-6

  • Online ISBN: 978-3-642-95553-2

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