Skip to main content
SpringerLink
Log in

Pankreaskarzinom

  • Chapter
Pankreaschirurgie

Part of the book series: Die Praxis der Chirurgie ((PRAXCHIR))

  • 17 Accesses

Zusammenfassung

Als Pankreaskarzinom im engeren anatomopatho-logischen Sinne wird das duktale Adenokarzinom des exokrinen Pankreas bezeichnet. Es ist zu trennen vom Papillenkarzinom, von dem distalen Cho-ledochuskarzinom und dem seltenen Zystadeno-karzinom sowie vom Azinuszellkarzinom, welche global auch als periampulläre Karzinome zusammengefaßt werden. Entsprechend der Lokalisation unterscheidet man die Pankreaskopfkarzinome (72%) von den Korpus- und Schwanzkarzinomen (18%) (Abb. 15.1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 44.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Aarimaa M, Makela P (1980) The diagnosis of pancreatic and biliary malignancy by endoscopy and retrograde cholangiopancreatography. Scand J Gastroenterol 15:205–211

    Article  PubMed  CAS  Google Scholar 

  2. Abe M, Takahashi M (1981) Intraoperative radiotherapy: The Japanese experience. Int J Radiat Oncol Biol Phys 7:863–868

    Article  PubMed  CAS  Google Scholar 

  3. Abelev Gl (1971) Alpha-fetoprotein in oncogenesis and its association with malignant tumors. Adv Cancer Res 14:295–358

    Article  PubMed  CAS  Google Scholar 

  4. Allan BJ, White TT (1977) Bile: pancreatic cancer and the activation of pancreatic juice. Biochem Biophys Res Commun 79:485 90

    Google Scholar 

  5. Anderson A, Bergdhal L (1976) Carcinoma of the pancreas. Am Surg 42:173

    Google Scholar 

  6. Appelquist P, Viven M, Minkkinen Z, Kayanti M, Kostianainen S, Rissanen P (1973) Operative finding, treatment and prognosis of carcinoma of the pancreas: An analysis of 267 cases. Z Surg Oncol 23:143

    Article  Google Scholar 

  7. Ashton MG, Axon ATR, Lintott DJ (1978) Lundh test and ERCP in pancreatic disease. Gut 99:910–915

    Article  Google Scholar 

  8. Aston SJ, Longmire WP (1976) Pancreatico-duodenal resection. Arch Surg 106:813

    Google Scholar 

  9. Audigier JC, Euvrard P, Tuyns AJ, Lambert R (1976) Mortalité par cancer du pancréas en France. Arch Mal App Dig 65:107

    CAS  Google Scholar 

  10. Banwo O, Versey J, Hobbs JT (1974) New oncofetal antigen for human pancreas. Lancet 1/7859:643–645

    Google Scholar 

  11. Batsakis JG, Kremers BJ, Thiessen MM et al. (1968) Biliary tract enzymology: A clinical comparison of serum alkaline phosphatase, leucine aminopeptidase and 5’ nuclotidase. Am J Clin Pathol 50:485–490

    PubMed  CAS  Google Scholar 

  12. Beazley RM (1981) Needle biopsy diagnosis of pancreatic cancer. Cancer 47:1685–1687

    Article  PubMed  CAS  Google Scholar 

  13. Beger HG, Bittner R (1986) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Book  Google Scholar 

  14. Benarde AM, Weiss W (1977) A cohort analysis of pancreatic cancer 1939-1969. Cancer 39:1260–1263

    CAS  Google Scholar 

  15. Bender RA, Brennan MF (1978) The role of percutaneous liver biopsy in the pretreatment evaluation of pancreatic adenocarcinoma. Am J Surg 135:207

    Article  PubMed  CAS  Google Scholar 

  16. Bergstran DO, Ahlberg JA, Ewerth S, Hellers G, Holmstrom B (1978) A retrospective study of carcinoma of the pancreas with special reference to the results of surgical treatment. Acta Chir Scand 482:26

    Google Scholar 

  17. Björck S, Svensson JO, MacPherson S, Edlund Y (1981) Cancer of the head of the pancreas and chole-doco-jéjunal junction. A clinical study of 88 Whipple resections. Acta Chir Scand 147:353–359

    PubMed  Google Scholar 

  18. Bloom P, Steez ML (1975) Pancreato-duodenectomy results when the operation is performed infrequently. Arch Surg 110:1455–1457

    Article  PubMed  CAS  Google Scholar 

  19. Bowers RF (1964) What can be done for carcinoma of the pancreas? Clin Med 71:59

    PubMed  CAS  Google Scholar 

  20. Braach JW, Gray BN (1977) Considerations that lower pancreato-duodenectomy mortality. Am J Surg 133:480–484

    Article  Google Scholar 

  21. Brooks JR, Culebras JM (1976) Cancer of the pancreas: Palliative operation, Whipple procedure or total pancreatectomy. Am J Surg 131:516

    Article  PubMed  CAS  Google Scholar 

  22. Brunschwig A (1937) Resection of the head of pancreas and duodenum for carcinoma — Pancreato duo-denectomy. Surg Gynecol Obstet 65:681

    Google Scholar 

  23. Buckwalter JA, Lawton RL, Tridick RT (1965) Bypass operations for neoplastic biliary tract obstruction. Am J Surg 109:100

    Article  PubMed  CAS  Google Scholar 

  24. Burtin P, Bara J (1982) Les antigènes des tumeurs digestives. Actualités Chirurgicales de l’A.F.C, tome 2. Masson, Paris

    Google Scholar 

  25. Carey LC (1985) The alimentary tract. New York City, May 14-15, 1985

    Google Scholar 

  26. Castellanos J, Manifacio G, Lillehei RC étal. (1976) Total pancreatectomy for ductal carcinoma of the head of the pancreas. Current status. Am J Surg 131:595

    Article  PubMed  CAS  Google Scholar 

  27. Champault G, Altmann JJ, Boutelier PH (1982) Le cancer du pancreas — Perspectives d’avenir. Actual Dig 4:107–109

    Google Scholar 

  28. Chapuis Y, Catala M, Piece S, Bronnette P (1983) Réflexions sur le traitement des cancers du pancréas. Chirurgie 109:357–358

    PubMed  CAS  Google Scholar 

  29. Chatal JF (1983) Détection des tumeurs par des anticorps monoclonaux radio-marqués en tomoscintigra-phie. Presse Méd 12/38:2361–2363

    Google Scholar 

  30. Chigot JP, Riguet M, Ahualli C, Clot JP, Mercadier M (1982) Les résultats des exérèses dans les cancers de la tête du pancréas. J Chir (Paris) 119/6-7:411 14

    Google Scholar 

  31. Child CG, Ellis JJ (1951) Radical duodenopancreatec-tomy. Ann Surg 134:80–86

    Article  PubMed  Google Scholar 

  32. Child CG, Holswade GR, McClure RD Jr, Gore AL, O’Neill EA (1952) Pancreaticoduodenectomy with resection of the portal vein in the macaka mulata monkey and in man. Surg Gynecol Obstet 94:31 5

    Google Scholar 

  33. Clemens M, Meyer J, Bunte H, Sasse W (1986) Perioperatives staging und Münsteraner TNM Klassifikation beim Papillen und Pankreaskarzinom. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer Berlin Heidelberg New York Tokyo, S 107–113

    Google Scholar 

  34. Cohen ZR, Kuchta N, Geller N, Shires T, Dineen P (1982) Pancreaticoduodenectomy: A 40 year experience. Ann Surg 195:608

    Article  PubMed  CAS  Google Scholar 

  35. Collins JJ, Craighead JE, Brooks JR (1966) Rational for total pancreatectomy for carcinoma of the pancreatic head. N Engl J Med 274:599

    Article  PubMed  Google Scholar 

  36. Collure DWD, Burns GP, Schenk WG Jr (1974) Clinical, pathological and therapeutic aspects of carcinoma of the pancreas. Am J Surg 128:683

    Article  PubMed  CAS  Google Scholar 

  37. Connely RR, Levin DL (1986) Epidemiologie des Pankreaskarzioms. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  38. Cooperman AM, Hester FP, Marboe CA, Helmreich ZV, Peszin KH (1981) Pancreatoduodenal resection and total pancreatectomy. An institutional review. Surgery 90:707

    PubMed  CAS  Google Scholar 

  39. Cotton PB (1984) Endoscopic methods for relief of malignant obstructive jaundice. World J Surg 8:854–861

    Article  PubMed  CAS  Google Scholar 

  40. Coutsofides T, Macdonald J, Shibata HR (1977) Carcinoma of the pancreas and periampullary region: A 41 year experience. Ann Surg 186:730

    Article  Google Scholar 

  41. Crile G (1970) The advantages of bypass operations over radical pancreatoduodenectomy in the treatment of pancreatic carcinoma. Surg Gynecol Obstet 130:1049

    PubMed  Google Scholar 

  42. Crollari S, Bernardoni A, Covello E, Palumbo P, Ma-ceratini R (1984) Valutazione del CEA nel cancro del pancreas. Atti delle Giornate di Chirurgia Oncologica. Casa del libro, Roma, pp 459–462

    Google Scholar 

  43. Cubilla AL, Fitzgerald PJ (1976) Morphologic lesions associated with human primary invasive non-endocrine pancreas cancer. Cancer Res 36:2690

    PubMed  CAS  Google Scholar 

  44. Cuschieri A, Hall AW, Clark J (1978) Value of lapa-roscopy in the diagnosis and management of pancreatic carcinoma. Gut 19:672

    Article  PubMed  CAS  Google Scholar 

  45. Czernichow P, Lerebours E, Hecketsweiler P, Colin R (1985) Epidemiologie temporo-spatiale du cancer du pancréas. Etude de mortalité internationale et française. Gastroenterol Clin Biol 9:767–775

    PubMed  CAS  Google Scholar 

  46. Dekker A, Lloyd JC (1979) Fine-needle aspiration biopsy in ampullary and pancreatic carcinoma. Arch Surg 114:592–596

    Article  PubMed  CAS  Google Scholar 

  47. Diamond D, Fisher B (1975) Pancreatic cancer. Surg Clin North Am 55:363

    PubMed  CAS  Google Scholar 

  48. Die Goyänes A, Pack GT, Bowden L (1971) Cancer of the body and tail of the pancreas. Rev Surg 26:153

    Google Scholar 

  49. Di Magno EP, Malagelada JR, Taylor WF, Co VL (1977) A prospective comparison of current diagnostic tests for pancreatic cancer. N Engl J Med 297:737

    Article  Google Scholar 

  50. Dooley JS, Olney J, Dick R, Sherlock S (1979) Non surgical treatment of biliary obstruction. Lancet 11:1040

    Article  Google Scholar 

  51. Douglass HO Jr (1974) Carcinoma of the head of the pancreas and periampullary region. Surg Ann 6:161

    Google Scholar 

  52. Douglass HO, Holyoke ED (1974) Pancreatic cancer: Initial treatment as the determinant of survival. JAMA 229:793

    Article  PubMed  Google Scholar 

  53. Doutre LP, Perissat J, Bobois JP, Grenet J (1975) La survie post-opératoire des cancers ictérigènes du pancréas. A propos de 172 interventions faites en 8 ans. Chirurgie 101:836

    PubMed  CAS  Google Scholar 

  54. Drapanas TH (1973) Regional resection for pancreatic carcinoma. Surgery 73:321–322

    PubMed  CAS  Google Scholar 

  55. Du Plessis DJ (1970) The palliative operation for obstructive jaundice due to carcinoma of the pancreas. S Afr J Surg 8:11

    PubMed  CAS  Google Scholar 

  56. Edis AJ, Kiernan PD, Taylor WF (1980) Attempted curative resection of ductal carcinoma of the pancreas. Mayo Clin Proc 55:531–536

    PubMed  CAS  Google Scholar 

  57. Ellison EC, Van Aman ME, Carey LC (1984) Preoperative transhepatic biliary decompression in pancreatic and periampullary cancer. World J Surg 8:862–871

    Article  PubMed  CAS  Google Scholar 

  58. Elmslie RG, Slavotineck AH (1972) Surgical objectives in unresected cancer of the head of the pancreas. Br J Surg 69:508

    Article  Google Scholar 

  59. Evans BP, Ochsner A (1957) The gross anatomy of the lymphatics of the human pancreas. Surgery 36:177

    Google Scholar 

  60. Forrest JF, Longmire WP (1979) Carcinoma of the pancreas and periampullary region. A study of 279 patients. Ann Surg 189:129

    Article  PubMed  CAS  Google Scholar 

  61. Fortner JG (1973) Regional resection of cancer of pancreas. A new surgical approach. Surgery 73:307–320

    PubMed  CAS  Google Scholar 

  62. Fortner JG (1973) Regional resection of cancer of the pancreas. A new surgical approach. Surgery 73:307–320

    PubMed  CAS  Google Scholar 

  63. Fortner JG (1974) Recent advances in pancreatic cancer. Surg Clin North Am 54:859–863

    PubMed  CAS  Google Scholar 

  64. Fortner JG (1980) Cancer of the pancreas. Letter to the editor. N Engl J Med 302:232

    Article  PubMed  CAS  Google Scholar 

  65. Fortner JG (1981) Median arcuate ligament abstruc-tion of celiac axis and pancreatic cancer. Ann Surg 194:698–700

    Article  PubMed  CAS  Google Scholar 

  66. Fortner JG (1981) Surgical principles for pancreatic cancer. Regional total and subtotal pancreatectomy. Cancer 47:1712–1718

    Article  PubMed  CAS  Google Scholar 

  67. Fortner JG (1984) Regional pancreatectomy for cancer of the pancreas, ampulla and other related sites. Tumor staging and results. Ann Surg 199:418–426

    Article  PubMed  CAS  Google Scholar 

  68. Fortner JG, Dong KK, Cubilla A, Turnbull A, Pahnke LD, Shills ME (1977) Regional pancreatectomy: En bloc pancreatic portal vein and lymph node resection. Ann Surg 186:42

    Article  PubMed  CAS  Google Scholar 

  69. Funovics ZM, Fritsch A (1986) Determination und Langzeitsüberlebensraten nach Radikaloperation beim Pankreaskarzinom. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  70. Gall FP (1986) Die subtotale Duodenopankreatekto-mie (DP) für Therapie des Pankreaskarzinoms. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  71. Gallitano A, Fransen H, Martin RG (1968) Carcinoma of the pancreas. Cancer 22:939

    Article  PubMed  CAS  Google Scholar 

  72. Gilsdorf RB, Spanos P (1973) Factors influencing morbidity and mortality in pancreatico-duodenec-tomy. Ann Surg 177:332–337

    Article  PubMed  CAS  Google Scholar 

  73. Glantz G, Ozeran RS (1966) Role of gastroenterostomy in management of pancreatic carcinoma. Am Surg 32:670

    PubMed  CAS  Google Scholar 

  74. Glassmann WS, Johnston PW (1955) Palliative surgery in carcinoma of the pancreas. Geriatrics 10:4560

    Google Scholar 

  75. Glenn F, Thorbjarnarson B (1964) Carcinoma of the pancreas. Ann Surg 159:945

    Article  PubMed  CAS  Google Scholar 

  76. Gögler H, Bittner R, Beger HG (1986) Überlebenszeiten und partielle Duodenopankreatektomie in Ab-läufigkeit von der Tumorgrösse. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  77. Gold P, Freedman SO (1965) Specific carcino-embryo-nic antigens of the human digestive system. J Exp Med 122:467–481

    Article  PubMed  CAS  Google Scholar 

  78. Goldenberg DM, Deland F, Kim E et al. (1978) Use of radiolabeled antibodies to carcino-embryonic antigen for the detection and localization of diverse cancers by external photoscanning. N Engl J Med 298/25:1384–1386

    Google Scholar 

  79. Goldman RD, Kaplan NO, Hall TC (1964) Lactic des-hydrogenese in human neoplastic tissues. Cancer Res 24:389–399

    PubMed  CAS  Google Scholar 

  80. Grözinger KH (1970) Chronische Pankreas — Erkrankungen und Pankreaskarzinom. Münch Med Wo-chenschr 24:1148–1151

    Google Scholar 

  81. Gudjonsson B, Livstone EM, Spiro HM (1978) Cancer of the pancreas: Diagnostic accuracy and survival statistics. Cancer 42:2494

    Article  PubMed  CAS  Google Scholar 

  82. Gunderson LL, Martin JK, Byer DE et al. (1984) Intraoperative and external beam irradiation with or without resection: Mayo pilot experience. Mayo Clin Proc 59:691–699

    PubMed  CAS  Google Scholar 

  83. Hancke S, Holm H, Koch F (1973) Ultrasonically guided percutaneous fine-needle biopsy of the pancreas. Surg Gynecol Obstet 140:361

    Google Scholar 

  84. Hansen HJ, Snyder JJ, Miller E et al. (1974) Carcino-embryonic antigen (C.E.A.) assay: A laboratory adjunct in the diagnosis and management of cancer. Hum Pathol 5:139–147

    Article  PubMed  CAS  Google Scholar 

  85. Hatfield ARW, Terblanche J, Fataaz S et al. (1982) Preoperative external biliary drainage in obstructive jaundice. Lancet XXIII: 896–898

    Google Scholar 

  86. Hermanek P, Giedl Z (1986) Lymphogene Metastasierung des Pankreas und periampullären Karzinoms. Häufigkeit, Topographie. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo, S 114–119

    Chapter  Google Scholar 

  87. Hermreck AS, Thomas CJ, Friesen SR (1974) Importance of pathologie staging in the surgical management of adenocarcinoma of the exocrine pancreas. Am J Surg 127:653–657

    Article  PubMed  CAS  Google Scholar 

  88. Hertzberg J (1974) Pancreatico-duodenal resection and bypass operation in patients with carcinoma of the head of the pancreas, ampulla and distal end of the common duct. Acta Chir Scand 140/7:523–527

    Google Scholar 

  89. Hicks RE, Brooks JR (1971) Total pancreatectomy for ductal carcinoma. Surg Gynecol Obstet 133:16

    PubMed  CAS  Google Scholar 

  90. Hilden J, Aspelin P, Vehlin R (1979) Gray scale ultrasound and endoscopic ductography in the diagnosis of pancreatic disease. Acta Chir Scand 145: 239

    Google Scholar 

  91. Hillon MC, Faivre J, Milan C, Klepping C (1982) Epidemiologie du cancer du pancreas. Actual Dig 2:90–94

    Google Scholar 

  92. Hines LH, Burns RP (1976) Ten years experience treating pancreatic and periampullary cancer. Am Surg 42:441

    PubMed  CAS  Google Scholar 

  93. Hiraoka T, Wetanake E, Mochinaya M, Tashiro S, Miyanchi Y, Nakamura I, Yokoyama I (1984) Intraoperative irradiation combined with radical resection for cancer of the head of the pancreas. World J Surg 8:766–771

    Article  PubMed  CAS  Google Scholar 

  94. Hobbs JR, Knapp MC, Branfoot AC (1980) Pancreatic onco-foetal antigen (P.O.A.): Its frequency and localisation in humans. Oncodev Biol Med 1:37–48

    PubMed  CAS  Google Scholar 

  95. Hoffmann RE, Donegan WL (1975) Experience with pancreato-duodenectomy in a cancer hospital. Am J Surg 129:292–297

    Article  PubMed  CAS  Google Scholar 

  96. Höjer H (1978) Routine systemic prophylaxis with doxycycline in elective intestinal surgery. Acta Chir Scand 144:387–394

    PubMed  Google Scholar 

  97. Höhender LF, Meyer C, Marrie A, Alexiou D (1973) Les pancreatectomies subtotales: Le point de vue du chirurgien. Gastroenterol Med Hyg Genève 1070:5

    Google Scholar 

  98. Höhender LF, Marrie AJ (1976) Chirurgie des Pankreas — Chirurgische Operationslehre. Urban & Schwarzenberg, München

    Google Scholar 

  99. Höhender LF, Meyer CH, Marrie A, Pierrard TH, Calderoli H (1980) Le cancer du pancreas. Reflexions a propos de 147 cas. Ann Chir 34:775

    Google Scholar 

  100. Höhender LF, Bahnini J, Marrie A (1985) Cancer de la tête du pancréas. Encycl Méd Chir, Paris Foie-Pancréas. 7106 A10-5

    Google Scholar 

  101. Howard JM (1968) Pancreaticoduodenectomy: 41 consecutive Whipple resections without operative mortality. Ann Surg 168:629–640

    Article  PubMed  CAS  Google Scholar 

  102. Howard JM, Jordan GL Jr (1960) Surgical diseases of the pancreas. Lippincott, Philadelphia

    Google Scholar 

  103. Huguet CL, Tussiot J (1982) Ictère par obstruction. La chirurgie doit elle être précédée d’un drainage biliaire externe? Gastroenterol Biol Clin 5:219

    Google Scholar 

  104. Ihse I, Lilja P, Arnesjo B, Bengmark S (1977) Total pancreatectomy for cancer appraisal of 65 cases. Ann Surg 186:675–680

    Article  PubMed  CAS  Google Scholar 

  105. Kaiser MH, Barkin J, Redlhammer D (1978) Circulating carcinoembyonic antigen in pancreatic cancer. Cancer 42:1453

    Google Scholar 

  106. Kawanishi H, Scil JE, Pillard HM (1975) CEA and cytology of pancreatic fluid. Gastroenterology 68:923

    Google Scholar 

  107. Kern E (1976) Die Behandlung der kranken Bauchspeicheldrüse. Problematik der Whipple’schen Operation. In: Bartelheimer H, Classen M, Ossenberg FW (Hrsg) II Hamburger Med Symp, S 171

    Google Scholar 

  108. Kern E, Creutzwald W, Kümmerle F, Granier HP (1963) Radikale, palliative oder konservative Behandlung des Pankreaskarzinoms? Langenbecks Arch Chir 303:456–479

    Article  PubMed  CAS  Google Scholar 

  109. Knight RW, Carbourough ZP, Gross JC (1978) Adenocarcinoma of the pancreas. A ten year experience. Arch Surg 113:1401

    Article  PubMed  CAS  Google Scholar 

  110. Krön B (1977) Remplacement de la voie biliaire principale extra hépatique chez le chien par une prothèse en elastomère de silicone. J Chir (Paris) 114:237–256

    Google Scholar 

  111. Kron B (1977) Remplacement segmentaire de la voie biliaire extra hépatique chez le chien par une prothèse en elastomère de silicone. Application possible en chirurgie biliaire. Chirurgie 103:470–474

    PubMed  CAS  Google Scholar 

  112. Kron B, Régnier J (1981) Prothèse cholédocienne en elastomère de silicone. Technique opératoire. Nouv Presse Med 10:1933–1935

    PubMed  CAS  Google Scholar 

  113. Kümmerle F, Ruckert K (1984) Surgical treatment of pancreatic cancer. World J Surg 8:889–894

    Article  PubMed  Google Scholar 

  114. Kümmerle F, Kirschner P, Mangold G (1976) Zur Klinik und Chirurgie des Pankreaskarzinoms. Dtsch Wo-chenschr 101:729–734

    Google Scholar 

  115. Lansing PB, Blalock JB, Ochsner JL (1972) Pancreato-duodenectomy a retrospective revue 1949-1969. Am Surg 38:79

    CAS  Google Scholar 

  116. Launois B (1984) La chirurgie du pancréas pour cancer. Bordeaux Med 17:115–118

    Google Scholar 

  117. Lea AJ (1967) Neoplasm and environment factors. Ann R Coll Surg Engl 41:432 37

    Google Scholar 

  118. Leadbetter A, Foster RS, Haines CR (1975) Carcinoma of the pancreas. Am J Surg 129:356

    Article  PubMed  CAS  Google Scholar 

  119. Léger L (1969) Exploration radiochirurgicale des voies excrétrices du pancreas. Patel-Leger Tech Chir 12:339

    Google Scholar 

  120. Léger L, Bréhant J (1949) Le traitement radical du cancer de la tête du pancreas. Rapport au congrès de l’Association française de chirurgie, Paris

    Google Scholar 

  121. Levin DL, Conelly RR, Devesa SS (1981) Demographic characteristics of cancer of the pancreas. Mortality, incidence and survival. Cancer 47:1456–1458

    Article  PubMed  CAS  Google Scholar 

  122. Levin OL, Conelly RR (1981) Cancer of the pancreas. Available epidemiologic information and its implications. Cancer 47:1456–1458

    Article  PubMed  CAS  Google Scholar 

  123. Lin RS, Kessler H (1981) A multifocal model for pancreatic cancer in man epidemiologic evidence. JAMA 245:147–152

    Article  PubMed  CAS  Google Scholar 

  124. Linn BS, Goldstein HS (1969) Judgement in palliation of pancreatic carcinoma with an assist by the compu-tor. South Med J 62:116

    Article  PubMed  CAS  Google Scholar 

  125. Litwin MS (1979) In discussion Tryka AF. Ann Surg 190:381

    Google Scholar 

  126. Locke B, King H (1980) Cancer mortality risk among Japanese in the United States. J Natl Cancer Inst 65:1149–1156

    PubMed  CAS  Google Scholar 

  127. Longmire WP Jr ( 1984) Cancer of the pancreas: Palliative operation, Whipple-procedure, or total pancreatectomy. World J Surg 8:872–879

    Article  PubMed  Google Scholar 

  128. Longmire WP, Shafey OA (1966) Certain factors influencing survival after pancreaticoduodenal resection for carcinoma. Am J Surg 111:8

    Article  PubMed  Google Scholar 

  129. Ludwig K, Hilbert K, Schuste R (1984) Ist eine Palliativoperation beim inoperablen Pankreaskarzinom sinnvoll? Zentralbl Chir 109:550–553

    PubMed  CAS  Google Scholar 

  130. MacMahon B, Yen S, Trichopoulos D, Warren K, Nardi G (1981) Coffee and cancer of the pancreas. N Engl J Med 304/11:630

    Google Scholar 

  131. MacMahon B (1982) Risk factors for cancer of the pancreas. Cancer 50:2676

    PubMed  CAS  Google Scholar 

  132. Mahvi David M, Meyers WC, Bast RC, Scigier HJ, Metzgar RS (1985) Carcinoma of the pancreas. Therapeutic efficacy as defined by a sérodiagnostic test utilizing a monoclonal antibody. Ann Surg 202:440–445

    Article  Google Scholar 

  133. Maki T, Sato T, Kakizak G (1966) Pancreatoduodenectomy of periampullary carcinomas. Arch Surg 92:825–833

    Article  PubMed  CAS  Google Scholar 

  134. Malagelada JR (1979) Pancreatic cancer. An overview of epidemiology, clinical presentation and diagnosis. Mayo Clin Proc 54:459

    PubMed  CAS  Google Scholar 

  135. Marchai G, Bernette M (1974) Total pancreatectomy. An experimental study of 21 cases. Collegium International Chirurgicae Digestivae. Ill World Congress, Chicago

    Google Scholar 

  136. Marchai G, Bertrand L, Ciurena A, Marty R (1975) Duodeno-pancréatectomie totale isolée pour syndrome de Zollinger-Ellison-malin. Chirurgie 101:152–156

    Google Scholar 

  137. Martin EW, James KK, Hurtubise PE, Catalano P, Minton JP (1977) The use of CE.A. as an early indicator for gastro-intestinal tumor recurrence and second-look procedures. Cancer 39/2:440–446

    Google Scholar 

  138. McDevitt JB (1969) Parenchymatous carcinoma of the head of the pancreas. J Ir Med Assoc 62:390

    PubMed  CAS  Google Scholar 

  139. Meinke WB, Twomey PL, Guernsey JM, Frey CF, Higgins G, Keehn R (1983) Gastric outlet obstruction after palliative surgery for cancer of the head of the pancreas. Arch Surg 118:550

    Article  PubMed  CAS  Google Scholar 

  140. Mendoza CB, Easley GW (1974) Bypass procedure for palliation in obstructive jaundice. W Va Med J 70:27

    Google Scholar 

  141. Mercadier M, Clot JP, Mellieres D (1967) Accidents de la duodénopancréatectomie cephalique — incidence sur la technique. Mem Acad Chir 93:197

    Google Scholar 

  142. Mercadier M, Clot JP, Mellieres D, Campiez PH (1967) Technique des duodénopancréatectomies cé-phaliques. Ann Chir 21:672

    PubMed  CAS  Google Scholar 

  143. Mercadier M, Bacourt F, Chigot JP (1972) Résultats à 5 ans de la chirurgie des tumeurs pancréatiques. Arch Fr Mal App Dig 61:3590

    Google Scholar 

  144. Milan C, Faivre J, Hillon MC, Kleppmg C (1982) Le cancer du pancréas dans le département de la Côte d’Or. Gastroenterol Clin Biol 6:623–627

    PubMed  CAS  Google Scholar 

  145. Monge JJ (1967) Survival of patients with small carcinomas of the head of the pancreas; biliary intestinal bypass vs pancreaticoduodenectomy. Am Surg 166:908

    CAS  Google Scholar 

  146. Moossa AR (1982) Pancreatic cancer: Approach to diagnosis, selection for surgery and choice of operation. Cancer 50:2689

    PubMed  CAS  Google Scholar 

  147. Moossa AR, Lewis MH, Mackie CR (1979) Surgical treatment of pancreatic cancer. Mayo Clin Proc 54:468

    PubMed  CAS  Google Scholar 

  148. Moossa AR, Scott MH, Lavelle-Jones M (1984) The place of total and extended total pancreatectomy in pancreatic cancer. World J Surg 8:895–899

    Article  PubMed  CAS  Google Scholar 

  149. Moreaux J, Catale M, Merzano L (1984) Les résultats du traitement chirurgical du cancer du pancréas. Etude d’une série de 96 opérés. Gastroenterol Clin Biol 8/1:11–16

    Google Scholar 

  150. Morris PJ, Nardi GL (1966) Pancreaticaduodenal cancer experience from 1951 to 1980 with a look ahead and behind. Arch Surg 92:834

    Article  PubMed  CAS  Google Scholar 

  151. Morrow M, Hiloris B, Brennen MF (1984) Comparison of conventional surgical resection, radioactive implantation, and bypass procedures for exocrine carcinoma of the pancreas 1975-1980. Ann Surg 199:1–5

    CAS  Google Scholar 

  152. Nakase A, Matsumoto U, Uchida H, Honjo I (1977) Surgical treatment of cancer of the pancreas and the periampullary region: Cumulative results in 57 institutions in Japan. Ann Surg 183:52

    Article  Google Scholar 

  153. Nishimura A, Nakano M, Otsu H et al. (1984) Intraoperative radiotherapy for advanced carcinoma of the pancreas. Cancer 54:2375–2384

    Article  PubMed  CAS  Google Scholar 

  154. Norlander A, Kalin B, Sundblad R (1982) Effect of percutaneous transhepatic drainage upon liver function and post-operative mortality. Surg Gynecol Obstet 155:161–166

    PubMed  CAS  Google Scholar 

  155. Obertop M, Bruining HA, Schattenkerk ME, Eggink WF, Jaekel J, van Houten H, Operative approach to cancer of the head of the pancreas and the periampullary region. Br J Surg 1982, oct. 69 (10) 573–576

    Google Scholar 

  156. Otto R, Deyhle P, Pedio L (1983) Biopsia percutanea dei tumori del pancreas per aspirazione con ago sottile guidata ecograficamente sotto controllo visivo permanente. Minerva Dietol Gastroenterol 29:71

    PubMed  CAS  Google Scholar 

  157. Park R, Sivar M, Talbert W Jr (1977) Pancreatitis with coexistent pancreatic duct stone and carcinoma. Early diagnosis by endoscopic retrograde pancreatography. Arch Intern Med 137:924–926

    Article  Google Scholar 

  158. Peiper H J (1977) Die chirurgische Therapie des Pan-kreaskarcinoms. Vortrag Gastroenterologisches Seminar, Hannover

    Google Scholar 

  159. Pichlmayr R, Rumpf KD (1986) Resektionstherapie beim Pankreaskarzinom: Chirurgische Technik, postoperative Komplikationen, Spätergebnisse. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  160. Pietri H, Sahel J, Sarles H (1977) Diagnosis of cancer of the pancreas by echotomography, endoscopic wir-sungography, arteriography and other means. Prog Gastroenterol 3:617

    Google Scholar 

  161. Pipes KE, Pareira MD (1958) Duodenal obstruction appearing after palliative biliary diversion for pancreatic carcinoma. Surgery 44:636

    PubMed  CAS  Google Scholar 

  162. Pistolesi GF, Marzoli GP, Colosso PQ, Peduzoli P, Proceed C (1978) Computed tomography in surgical pancreatic emergencies. J Comput Assist Tomogr 2:165–169

    Article  PubMed  CAS  Google Scholar 

  163. Pistolesi GF, Proceed C, Fugazzole C (1982) Approche radiologique des maladies du pancréas exocrine. Radiol J CEPUR 2:149–219

    Google Scholar 

  164. Pliam BM, Remine WH (1977) Further evaluation of total pancreatectomy. Arch Surg 110:506

    Google Scholar 

  165. Poilleux J, Rigot J (1978) Résultats comparés des différents traitements chirurgicaux des cancers du pancréas. Ann Gastroenterol 14/6:399–404

    Google Scholar 

  166. Pollard HM, Anderson WAD, Brooks FP et al. (1981) Staging of cancer of the pancreas. Cancer 47:1631–1637

    Article  Google Scholar 

  167. Porter EA (1970) Carcinoma of the pancreas. NZ Med J 71:288

    CAS  Google Scholar 

  168. Priestley JT, Camfort MW, Radchiffe J Jr (1944) Total pancreatectomy for hyperinsulinism due to an islet cell adenoma, survival and cure at 16 months after operation presentation of metabolic studies. Ann Surg 119:211

    Article  PubMed  CAS  Google Scholar 

  169. Priestley JT, Comfort MW, Spragne EG (1949) Total pancreatectomy for hyperinsulinism due to an islet cell adenoma, following report Five and one half years after operation, including metabolic studies. Ann Surg 130:211

    Article  PubMed  CAS  Google Scholar 

  170. Reed K, Vose P, Jarstfer B (1976) Pancreatic cancer diagnosis: Preliminary evaluation of a prospective study. J Surg Res 21:113

    Article  Google Scholar 

  171. Reed K, Vose PC, Jartsfer BS (1979) Pancreatic cancer — 30 year review (1947-1977). Am J Surg 138:929

    CAS  Google Scholar 

  172. Remine WH, Priestley JT, Judd ES, King JN (1970) Total pancreatectomy. Ann Surg 172:596–604

    Article  Google Scholar 

  173. Richards AB, Chir M, Sosin H (1973) Cancer of the pancreas, the value of radical and palliative surgery. Ann Surg 177:325

    Article  PubMed  CAS  Google Scholar 

  174. Rosalki SB, Tarlow D, Rau D (1971) Plasma glutamyl transpeptidase elevation in patients receiving enzyme inducing drugs. Lancet 11/7720:376–377

    Google Scholar 

  175. Rückert K, Kümmerle F (1986) Ergebnisse der totalen Duodenopankreatektomie als Regeloperation beim Pankreaskarzinom. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  176. Ruillova LA, Herhey CD (1976) Experience with 21 pancreaticoduodenectomies. Arch Surg 111:27-30

    Google Scholar 

  177. Safi F, Bittner R, Büchler M, Malfertheimer F, Beger HG (1986) Die Wertigkeit des monoklonalen Antikörpers CA 19-9 in der Differentialdiagnose der Pankreas-erkrankungen. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo, S 145–153

    Chapter  Google Scholar 

  178. Safrany L, Tari J, Barna L, Torok I (1973) Endoscopie retrograde cholangiography experience of 168 examinations. Gastrointest Endosc 19:163–168

    Article  PubMed  CAS  Google Scholar 

  179. Sarr MG, Cameron JL (1982) Surgical management of unresectable carcinoma of the pancreas. Surgery 91/2:123

    Google Scholar 

  180. Sarr MG, Cameron JL (1984) Surgical palliation of unresectable carcinoma of the pancreas. World J Surg 8:906–918

    Article  PubMed  CAS  Google Scholar 

  181. Sato T, Saitoh Y, Noto N, Matsuno S (1978) Factors influencing the late results of operation for carcinoma of the pancreas. Am J Surg 136:582

    Article  PubMed  CAS  Google Scholar 

  182. Shapiro IM (1975) Adenocarcinoma of the pancreas. A statistical analysis of biliary bypass versus Whipple resection in good risk patients. Ann Surg 182:715–721

    Article  PubMed  CAS  Google Scholar 

  183. Sheedy PF, Stephens DH, Hattery RR, Maccarty RL (1977) Computed tomography in the evaluation of patients with suspected carcinoma of the pancreas. Radiology 124:731

    PubMed  Google Scholar 

  184. Shipley WU, Tepper JE, Warshaw AL, Orlow EL (1984) Intraoperative radiation therapy for patients with pancreatic carcinoma. World J Surg 8:929–934

    Article  PubMed  CAS  Google Scholar 

  185. Shipley WU, Wood WC, Tepper JE et al. (1984) Intraoperative electron beam irradiation for patients with unresectable pancreatic carcinoma. Am Surg 200:289–294

    CAS  Google Scholar 

  186. Sindelar WF, Kinsella T, Tepper JE, Travis EL, Rosenberg SA, Glatstein E (1983) Experimental and clinical studies with intraoperative radiotherapy. Surg Gynecol Obstet 157:205–209

    PubMed  CAS  Google Scholar 

  187. Smith PE, Krementz ET, Reed RJ, Bufkin WJ (1967) An analysis of 600 patients with carcinoma of the pancreas. Surg Gynecol Obstet 124:1288

    PubMed  CAS  Google Scholar 

  188. Solassol CL, Joyeux H, Solassol CH, Pujol H, Romieu CL (1978) Chirurgie régionale des cancers du pancréas à propos de 23 cas. Chirurgie 104:131–140

    PubMed  CAS  Google Scholar 

  189. Solassol C, Joyeux H, Yakoun M, Blanc F, Bories P (1984) La pancréatectomie régionale dans le traitement de l’adéno-carcinome du pancréas. A propos de 41 cas. Gastroenterol Clin Biol 8:17–21

    PubMed  CAS  Google Scholar 

  190. Spohn K, Fux HD, Tewes G, Hahn K (1975) Das Pankreas Carcinom Palliative Operationen. Langen-becks Arch Chir 330:267

    Article  Google Scholar 

  191. Stuart M, Keo T, Hermann RE, Hoeu SO (1971) Palliation of malignant obstruction of the common bile duct by side to side choledocoduodenostomy. Am J Surg 121:505

    Article  PubMed  CAS  Google Scholar 

  192. Suzuki T, Imamura M, Tamura K (1979) Correlative evaluation of angiography and pancreatoductography in relation to surgery for cancer of the pancreas. Surgery 85:642

    Google Scholar 

  193. Tepper J, Nardi G, Snit H (1976) Carcinoma of the pancreas experience from 1963-1973. Cancer 37:1519–1524

    CAS  Google Scholar 

  194. Traverso LW, Longmire WP Jr (1978) Preservation of the pylorus during pancreaticoduodenectomy. Surg Gynecol Obstet 146:959–962

    PubMed  CAS  Google Scholar 

  195. Trede M (1985) The surgical treatment of pancreatic carcinoma. Surgery 97:28–35

    PubMed  CAS  Google Scholar 

  196. Trede M, Hoffmeister A (1981) Chirurgische Therapie des Pankreaskarzinoms. Therapiewoche 32:918

    Google Scholar 

  197. Trede M, Hoffmeister AW (1986) Die partielle Duodenopankreatektomie beim Pankreaskarzinom: Indikation, Technik, Ergebnisse. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo, S 269–282

    Chapter  Google Scholar 

  198. Trede M, Kersting KH, Hoffmeister A (1977) Das Pankreaskopfkarzinom. Münch Med Wochenschr 119/18:617

    Google Scholar 

  199. Tryka AF, Brooks JR (1979) Histopathology in the evaluation of total pancreatectomy for ductal carcinoma. Ann Surg 190:373

    Article  PubMed  CAS  Google Scholar 

  200. Van Heerden JA (1984) Pancreatic resection for carcinoma of the pancreas: Whipple versus total pancreatectomy — An institutional perspective. World J Surg 8:880–888

    Article  PubMed  Google Scholar 

  201. Van Heerden JA, Remine WH, Weiland LH, Mclll-rath DC, Ilstrup DM (1981) Total pancreatectomy for ductal adenocarcinoma of the pancreas. Am J Surg 142:308–311

    Article  PubMed  Google Scholar 

  202. Van Kemmel M, Rwamasirabo E, Lagache G (1983) 152 cancers du pancréas. Classification sectorielle et options thérapeutiques. Chirurgie 109:260–267

    Google Scholar 

  203. Van Waes L, Van Maele V, Demeulamaere L, Mlams-sens C (1977) Carcinoma of the pancreas presenting as relapsing pancreatitis. Am J Gastroenterol 68:88

    PubMed  Google Scholar 

  204. Venot J, Vincent D, Clement MN, Beck C (1984) Evaluation d’un marqueur tumoral du cancer du pancréas. Résultats préliminaires. Presse Méd 13/7:440–441

    Google Scholar 

  205. Warren K, Christophi C, Armendariz H (1983) Current trends in the diagnosis and treatment of carcinoma of the pancreas. Am J Surg 145:813

    Article  PubMed  CAS  Google Scholar 

  206. Warshaw AL, Torchiana DL (1985) Delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy. Surg Gynecol Obstet 160:1 4

    Google Scholar 

  207. Warshaw AL, Tepper JE, Shipley WU (1986) Laparos-copy in the staging and planning of therapy for pancreatic cancer. Am J Surg 151:76–80

    Article  PubMed  CAS  Google Scholar 

  208. Webster DJT (1975) Carcinoma of the pancreas and periampullary region — A clinical study in a district general hospital. Br J Surg 62:130

    Article  PubMed  CAS  Google Scholar 

  209. White TT (1973) Long term follow-up of fifty patients with pancreaticojejunostomy. Surg Gynecol Obstet 136:353

    PubMed  CAS  Google Scholar 

  210. Weill F, Marmier A, Peroneau L, Zeltner F, Bonegoin A (1979) Fiabilité de l’exploration ultrasonore du pancréas. Résultat du 266 observations contrôlées. J Radiol 60:9–11

    CAS  Google Scholar 

  211. White TT, Murât J, Morgan A (1968) The immediate surgical management of a mass on the head of the pancreas. Northwest Med 67:731

    PubMed  CAS  Google Scholar 

  212. Wijayanagar R, Tobins SH (1970) Evaluation of palliative operation for carcinoma of the head of the pancreas. A ten year study. Mt Sinai J Med (NY) 37:115

    Google Scholar 

  213. Williams RD, Elliott DW, Zollinger RM (1960) Surgery for malignant jaundice. Arch Surg 80:992

    Article  PubMed  CAS  Google Scholar 

  214. Winegarner FG, Hague WH, Elliott DW (1966) Tissue diagnosis and surgical management of malignant jaundice. Am J Surg 111:5

    Article  PubMed  CAS  Google Scholar 

  215. Wood R, Hall A, Moossa AH, Levin B, Skinner D (1976) Pancreatic cancer diagnosis: Preliminary evaluation of a prospective study. J Surg Res 21:113

    Article  PubMed  CAS  Google Scholar 

  216. Wynder EL, Mabuchi K, Maruchi N, Fortner JG (1973) Epidemiology of cancer of the pancreas. J Natl Cancer Inst 50:645–667

    PubMed  CAS  Google Scholar 

  217. Zamcheck N, Martin EW (1981) Factors controlling the circulating CEA levels in pancreatic cancer. Cancer 47:1620

    Article  PubMed  CAS  Google Scholar 

  218. Akwari OE, Van Heerden JA, Adson MA, Baggenstoss AH (1977) Radical pancreatoduodenectomy for cancer of the papilla of Vater. Arch Surg 112:451–456

    Article  PubMed  CAS  Google Scholar 

  219. Aston SJ, Longmire WP Jr (1973) Pancreaticoduodenal resection. Twenty years experience. Arch Surg 106:813–817

    Article  PubMed  CAS  Google Scholar 

  220. Baker RR, Pioroda CL, Lee JM (1873) Carcinoma of the head of the pancreas and periampullary region. John Hopkins Med 132:212–221

    Google Scholar 

  221. Bartels P (1909) Das Lymphgefäßsystem. Fischer, Jena

    Google Scholar 

  222. Blievernicht SW, Neifeld JP, Terz JJ, Lawrence W Jr (1980) The rôle of prophylactic gastrojejunostomy for unresectable periampullary carcinoma. Surg Gynecol Obstet 151:794

    PubMed  CAS  Google Scholar 

  223. Blumgart LH, Kennedy A (1973) Carcinoma of the ampulla of Vater and duodenum. Br J Surg 60:33–40

    Article  PubMed  CAS  Google Scholar 

  224. Brooks JR (1983) Choices in the surgical treatment of the head and ampulla of the pancreas. 69th Annual Clinical Congress American College of Surgeons. Postgrad Course 3:45–48

    Google Scholar 

  225. Büchler M, Bittner R, Beger HG (1986) Resektionstherapie des Papillenkarzinoms: Chirurgische Technik, postoperative Komplikationen, Spätergebnisse. In: Beger HG, Bittner B (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  226. Clemens M, Meyer Z, Bunte H, Sasse W (1986) Perioperatives staging und Klassifikation beim Papillenpan-kreaskarzinom. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  227. Colton T (1976) Life table method in statistica in mediana. Piccin, Padova, pp 48–53

    Google Scholar 

  228. Couinaud C (1963) Anatomie de l’abdomen. Doin, Paris

    Google Scholar 

  229. Couinaud C, Huguet C (1966) Le temps d’exerese dans la duodeno-pancreatectomie totale. J Chir (Paris) 91/2:181–190

    Google Scholar 

  230. Coutsofides T, MacDonald J, Shibata HR (1977) Carcinoma of the pancreas and periampullary region. A 41 year experience. Ann Surg 186:730–733

    Article  Google Scholar 

  231. Crane M J, Gobbel WG Jr, Scott WH (1973) Surgical experience with malignant tumours of the ampulla of Vater and duodenum. Surg Gynecol Obstet 137:56

    Google Scholar 

  232. Crile G Jr (1970) The advantages of bypass operations over radical pancreatoduodenectomy in the treatment of pancreas cancer. Surg Gynecol Obstet 130:1049

    PubMed  Google Scholar 

  233. Dabstein P, Simmonet P, Perarnan JM, Raabe JJ, Courrier A, Arbogast J, Hennequin J (1984) L’endoscopie thérapeutique pour cancer de l’ampoule de Vater. Sem Hop Paris 60:2963–2970

    Google Scholar 

  234. Dencker H (1972) Pancreaticoduodenectomy for periampullary tumours. Acta Chir Scand 138/3:293–300

    Google Scholar 

  235. Denker H (1972) Symptomatology of resectable periampullary carcinoma. Acta Chir Scand 138:613

    Google Scholar 

  236. Edmondson JA (1967) Tumour of the gallbladder and extrahepatic bile ducts. In: Letter of the tumour pathology, Section 3, fasc 26. Armed Forces Institute of Pathology, Washington

    Google Scholar 

  237. Fisch JC, Cleveland BR (1964) Pancreatoduodenectomy for periampullary carcinoma. Analysis of 38 cases. Ann Surg 159:469

    Article  Google Scholar 

  238. Gilsdorf RB, Spanos B (1973) Factors influencing morbidity and mortality in pancreaticoduodenectomy. Ann Surg 177/3:332–337

    Google Scholar 

  239. Hall TJ, Blackstone MO, Cooper MJ, Hughes RG, Moossa AR (1978) Prospective evaluation of endoscopic retrograde cholangiopancreatography in the diagnosis of periampullary cancers. Ann Surg 187:313

    Article  PubMed  CAS  Google Scholar 

  240. Huguet C (1981) La duodeno-pancreatectomie céphali-que et ses résultats dans le cancer du pancreas. Mallet, Paris, pp 69–71

    Google Scholar 

  241. Longmire WP Jr, Shafey OA (1966) Certains factors influencing survival after pancreatico-duodenal resection for carcinoma. Am J Surg 111:8–12

    Article  PubMed  Google Scholar 

  242. Makipour H, Coopermann A, Danzi JT, Famer RG (1976) Carcinoma of the ampulla of Vater. Review of 38 cases with emphasis on treatment and prognostic factors. Ann Surg 183/4:341–344

    Google Scholar 

  243. Marchai G, Hureau J (1978) Les tumeurs oddiennes. Monographie de l’Association Française de Chirurgie. Masson Paris

    Google Scholar 

  244. Michels NA (1966) Newer anatomy of the liver and its variant blood supply and collateral circulation. Am J Surg 112:337–347

    Article  PubMed  CAS  Google Scholar 

  245. Mongé JJ, Judd ES, Gage RP (1964) Radical pancreatoduodenectomy: A 22 year experience with the complications, mortality rate and survival rate. Ann Surg 160:711–722

    Article  PubMed  Google Scholar 

  246. Okuda K, Tanikawa E, Emura T et al. (1974) Nonsurgical percutaneous trans-hepatic cholangiography: Diagnostic significance in medical problems. Am J Dig Dis 19:21–36

    Article  PubMed  CAS  Google Scholar 

  247. Pezzuoli G, Spina GP (1980) I tumori della regione vate-riana. In: Beretta A (ed) Medicina clinica. Med Scient., Torino, pp 527–544

    Google Scholar 

  248. Ponka JL, Uthapa NS (1971) Carcinoma of the ampulla of Vater. Am J Surg 121/3:263–270

    Google Scholar 

  249. Puglionisi A, Nuzzo P, Costamana P, Masetti R, Mapi-strelle P, Coppola R (1982) Carcinoma of the ampulla of Vater: A plea for pancreato-duodenectomy. Ital J Surg Sci 12:23–27

    Google Scholar 

  250. Rumpf KD, Ostertag O, Pichlmayr R (1986) Das peripapilläre Karzinom. Ein fragwürdiger Terminus. In: Beger HG, Bittner B (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  251. Salmon PA (1966) Carcinoma of the pancreas and extra-hepatic biliary system. Surgery 60/3:554–565

    Google Scholar 

  252. Schlippert W, Lucke D, Anuras S, Christensen J (1978) Carcinoma of the papilla of Vater: A review of Fifty-seven cases. Am J Surg 135:763

    Article  PubMed  CAS  Google Scholar 

  253. Shalimov AA (1972) Pancreato-duodenal resection and treatment of periampullar zone cancer. Bull Soc Int Chir 31/2:100–102

    Google Scholar 

  254. Stephenson LW, Blackstone EH, Aldrete JS (1977) Radical resection for periampullary carcinomas. Results in 53 patients. Arch Surg 112:245–249

    Article  PubMed  CAS  Google Scholar 

  255. Toussaint J, De Toeuf J, Dunham F, Cremer M (1981) Les tumeurs oddiennes: étude clinique et résultats du traitement palliatif ou préopératoire par sphincteroto-mie endoscopique. Acta Gastroenterol Belg 44:250

    PubMed  CAS  Google Scholar 

  256. Treadwell TA, Jimenez-Chapa JF, White RR III (1978) Carcinoma of the ampulla of Vater. South Med J 71:365

    Article  PubMed  CAS  Google Scholar 

  257. Vankemmel M. Laurent JC, Salembier Y (1975) Cancers de l’ampoule de Vater et de la voie biliaire principale intrapancréatique. Modalités thérapeutiques et résultats. Ann Chir 29:254

    Google Scholar 

  258. Warren KW, Cattell RB, Blackburn JP, Nora PF (1962) Long term appraisal of pancreatico-duodenal resection for periampullary carcinoma. Ann Surg 155:653–662

    Article  PubMed  CAS  Google Scholar 

  259. Warren KW, Dai Du Choe Plaza J, Relihan M (1975) Results of radical resection for periampullary cancer. Ann Surg 181/5:534–540

    Google Scholar 

  260. Warshaw AL (1986) Therapie des periampullären Karzinoms. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  261. Waugh JM, Giberson RG (1957) Radical resection of the head of the pancreas and of the duodenum for malignant lesions: Some factors in operative technique and preoperative and postoperative care, with an analysis of 85 cases. Surg Clin North Am 37:965

    PubMed  CAS  Google Scholar 

  262. Whipple AO, Parsons WW, Mullins CR (1935) Treatment of carcinoma of the ampulla of Vater. Ann Surg 102:763

    Article  PubMed  CAS  Google Scholar 

  263. Williams JA, Cubilla A, MacLean BJ, Fortner JG (1979) Twenty two year experience with periampullary carcinoma at Memorial Sloan — Kettering Cancer Center. Ann Surg 138:662–665

    Article  CAS  Google Scholar 

  264. Wilson SN, Block GE (1974) Periampullary carcinoma. Arch Surg 108:539

    Article  PubMed  CAS  Google Scholar 

  265. Al-Abdulla SM, Hussey DH, Olson MH, Wright AE (1981) Experience with fast neutron therapy for unresectable carcinoma of the pancreas. Int J Radiat Oncol Biol Phys 7:165–172

    Article  PubMed  CAS  Google Scholar 

  266. Allen CV, Fletcher WS (1972) A pilot study on preoperative irradiation of recto sigmoid carcinoma. AJR 114:504–508

    CAS  Google Scholar 

  267. Biggs PJ, Epp ER, Ling CC, Novack DH, Michaelis HB (1981) Dosimetry, field shaping and other considerations for intra-operative electron therapy. Int J Radiat Oncol Biol Phys 7:875–884

    Article  PubMed  CAS  Google Scholar 

  268. Castro JR, Saunders WM, Quivery JM et al. (1982) Clinical problems in radiotherapy of carcinoma of the pancreas. Am J Clin Oncol 5:579–587

    Article  PubMed  CAS  Google Scholar 

  269. Cohen L, Awschalom M, Hendrickson F, Mansell J, Rosenberg I (1981) Neutron irradiation for pancreatic cancer. The Fermilab experience. Newsletter Nat Pancreas Cancer Project 6:16

    Google Scholar 

  270. Cubilla AL, Fortner J, Fitzgerald P (1978) Lymph node involvement in carcinoma of the head of the pancreas area. Cancer 41:880–887

    Article  PubMed  CAS  Google Scholar 

  271. Dobelbower RR Jr, Borgelt BB, Strubler KA, Kutcher GJ, Suntharalingam N (1980) Precision radiotherapy for cancer of the pancreas: Technique and results. Int J Radiat Oncol Biol Phys 6:1127–1133

    Article  PubMed  Google Scholar 

  272. Goldson AL, Ashaveri E, Espinoza MC et al. (1981) Single high dose intraoperative electrons for advances stage pancreatic cancer: Phase I pilot study. Int J Radiat Oncol Biol Phys 7:869–874

    Article  PubMed  CAS  Google Scholar 

  273. Handley WS (1934) Pancreatic cancer and its treatment by implanted radium. Am Surg 100:215–233

    CAS  Google Scholar 

  274. Haslam JB, Cavanaugh PJ, Stroup SL (1973) Radiation therapy in the treatment of irresectable adenocarcinoma of the pancreas. Cancer 32:1341–1345

    Article  PubMed  CAS  Google Scholar 

  275. Henschke UK (1956) Interstitial implantation with radioisotopes. In: Hahn PF (ed) Therapeutic use of artificial radioisotopes. Wiley, New York, pp 375–397

    Google Scholar 

  276. Hilaris BS, Roussis K (1975) Cancer of the pancreas. In: Hilaris BS, Acton MA (eds) Handbook of interstitial br achy therapy. Publishing Sciences Group, Acton, Massachusetts, pp 251-262

    Google Scholar 

  277. Hilaris BS, Andersson LL, Torita N (1978) Interstitial implantation of pancreatic cancer. Front Radiat Ther Oncol 12:62–71

    Google Scholar 

  278. Hohenberg G, Heckenthaler WH, Kogelnik HD, Kär-cher KH (1981) Rolle der Strahlentherapie in der Behandlung des Pankreaskarzinoms. Strahlentherapie 157:437–441

    PubMed  CAS  Google Scholar 

  279. Holm HH, Stroyer I, Hansen H, Stadil F (1981) Ultra-sonically guided percutaneous interstitial implantation of iodine 125 seeds in cancer therapy. Br J Radiol 54:665–670

    Article  PubMed  CAS  Google Scholar 

  280. Kaiser M, Ellenberg S, Levin B et al. (1983) Pancreatic cancer: Adjuvant combined radiation and chemotherapy following potentially curative resection (Meeting abstract). Proc Am Soc Clin Oncol 2:C-474

    Google Scholar 

  281. Kaul R, Cohen L, Hendrikson F, Awschalom M, Hrejsa AF, Rosenberg I (1981) Pancreatic carcinoma: Results with fast neutron therapy. Int J Radiat Oncol Biol Phys 7:173–178

    Article  PubMed  CAS  Google Scholar 

  282. Khandekar JD, Scanlon EF, Garces RM, Prasad G, Lawrence GA (1983) A phase II study with 5-FU and MethylCCNU (MECCNU) in carcinomas of the pancreas and stomach (Meeting abstract). Proc Am Assoc Cancer Res 23:615

    Google Scholar 

  283. Komaki R, Wilson F, Cox JD, Kline RW (1980) Carcinoma of the pancreas: Results of irradiation for unresectable lesions. Int J Radiat Oncol Biol Phys 6:209–212

    Article  PubMed  CAS  Google Scholar 

  284. Leer JW, van de Velde CJ, Vierhout PA (1981) Radiotherapie van carcinomen van gal wegen en pancreas. Ned Tijdschr Geneeskd 125:1160–1165

    PubMed  CAS  Google Scholar 

  285. Mameghan H, Karolis C (1982) The use of 125-1 interstitial implant and external beam radiotherapy in the management of inoperable pancreatic cancer. Ninth annual scientific meeting of the clinical oncological society of Australia, November 24-26, Sidney, Australia

    Google Scholar 

  286. Mortel CG, Frytak S, Hahn RG et al. (1981) Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-Fluo-rouracil), and high dose radiation + 5 Fluorouracil. The gastrointestinal tumor study group. Cancer 48:1805–1710

    Google Scholar 

  287. Nguyen TD, Bugat R, Combes PF (1982) Postoperative irradiation of carcinoma of the head of the pancreas area. Short-time tolerance and results to precision high-dose technique in 18 patients. Cancer 50:53–56

    Article  PubMed  CAS  Google Scholar 

  288. Pack GT, McNeer G (1938) Radiation treatment of pancreatic cancer. AJR 40:708–714

    Google Scholar 

  289. Quivey JM, Castro JR, Saunders WB et al. (1981) A prospective randomized (NCOG/RTOG) trial of conventional split course radiotherapy with 5-Fluorouracil (5-Fu) versus helium ion radiotherapy with 5-FU (A preliminary report). Proc Am Assoc Cancer Res 22:460

    Google Scholar 

  290. Schein PS, Smith FP, Dritschillo A, Stablein DM, Ahl-gren AD (1983) Phase I-II trial of combined modality FAM (5-Fluorouracil, Adriamycin and Mitomycin C) plus split course radiation (FAM-RT-FAM) for locally advanced gastric (LAG) and pancreatic (LAP) cancer: A midatlantic oncology program study (Meeting Abstract). Proc Am Soc Clin Oncol 2:C-491

    Google Scholar 

  291. Senter KL (1981) Implantation of 125-1 supplementing external radiation as treatment for carcinoma of the pancreas. In: George FW (ed) Modern interstitial and intracavitary radiation management, vol 6. Mason, New York, pp 132

    Google Scholar 

  292. Shipley WU, Gunderson LL, Nardi GL, Biggs PJ, Wood WC, Suit HD (1981) Intraoperative electron beam irradiation for patients with unresectable pancreatic carcinoma. Int J Radiat Oncol Biol Phys 7:1278

    Article  Google Scholar 

  293. Smith FP, Schein PS, Macdonald JS, Wooley PV, Or-nitz R, Rogers C (1981) Fast neutron irradiation for locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 7:1527–1531

    Article  PubMed  CAS  Google Scholar 

  294. Syed AM, Puthawala AA, Neblett DL (1983) Interstitial iodine-125 implant in the management of unresectable pancreatic carcinoma. Cancer 52:808–813

    Article  PubMed  CAS  Google Scholar 

  295. Tepper J, Nardi G, Suit H (1976) Carcinoma of the pancreas: Review of MGH experience from 1963-1973. Cancer 37:1519–1524

    CAS  Google Scholar 

  296. Upcott H (1912) Tumors of the ampulla of Vateri. Ann Surg 56:710–726

    Article  PubMed  CAS  Google Scholar 

  297. Wang CC, Schulz MD, Miller D (1972) Combined radiation therapy and surgery for carcinoma of the supraglottis and piriformis sinus. Am J Surg 124:551–554

    Article  PubMed  CAS  Google Scholar 

  298. Werft-Messing B van der (1973) Carcinoma of the bladder treated by preoperative irradiation followed by cystectomy. The second report. Cancer 32:1084–1088

    Article  Google Scholar 

  299. Whittington R, Bobelbower RR, Mohiuddin M, Rosato FE, Weiss SM (1981) Radiotherapy of unresectable pancreatic carcinoma: A six year experience with 104 patients. Int J Radiat Oncol Biol Phys 7:1639–1644

    Article  PubMed  CAS  Google Scholar 

  300. Wood WC, Shipley WU, Gunderson LL, Cohen AM, Nardi GL (1982) Intraoperative irradiation for unresectable pancreatic carcinoma. Cancer 49:1272–1275

    Article  PubMed  CAS  Google Scholar 

  301. Woodruff KH, Castro JR, Quivey JM et al. (1984) Postmortem examination of 22 pancreatic carcinoma patients treated with helium ion irradiation. Cancer 53:420–425

    Article  PubMed  CAS  Google Scholar 

  302. Yamada S, Ishibashi T, Sasauchi S, Takaj Y, Koyama K, Hoshino F (1984) A case of recurrent pancreatic carcinoma treated by low-dose-rate telecobalt therapy. Gan No Rinsho 30:75–80

    PubMed  CAS  Google Scholar 

  303. Al-Sarraf M, Vaughn CB, Reed ML, Vaitkevicius VK (1972) Combined 5-fluorouracil and vinblastine therapy for gastrointestinal and other solid tumors. Oncology 26:99–113

    Article  PubMed  CAS  Google Scholar 

  304. Andren-Sandberg A, Holmberg JT, Ihse I (1983) Treatment of unresectable pancreatic carcinoma with 5-fluorouracil, vincristine, and CCNU. Scand J Gastroenterol 18:609–612

    CAS  Google Scholar 

  305. Bitran JD, Desser RK, Kosloff MF, Billings AA, Shapiro CM (1979) Treatment of metastatic pancreatic and gastric adenocarcinomas with 5-fluorouracil, adriamycin and mitomycin C (FAM). Cancer Treat Rep 63:2049–2051

    CAS  Google Scholar 

  306. Broder LE, Carter SK (1973) Results of therapy with streptozotocin in 52 patients. Ann Intern Med 79:108–118

    PubMed  CAS  Google Scholar 

  307. Bruckner HW, Storch JA, Brown JC, Goldberg J, Chamberlin K (1983) Phase II trial of combination chemotherapy for pancreatic cancer with 5-fluorouracil, mitomycin C, and hexamethylmelamine. Oncology 40:165–169

    Article  PubMed  CAS  Google Scholar 

  308. Bukowski RM, Abderhalden RT, Hewlett JS, Weick JK, Groppe CW (1980) Phase II trial of streptozotocin, mitomycin C, and 5-fluorouracil in adenocarcinoma of the pancreas. Cancer Clin Trials 3:321–324

    PubMed  CAS  Google Scholar 

  309. Bukowski RM, Schacter LP, Groppe CW, Hewlett JS, Weick JK, Livingston RB (1982) Phase II trial of 5-fluorouracil, adriamycin, mitomycin C and streptozotocin (FAM-S) in pancreatic carcinoma. Cancer 50:197–200

    Article  PubMed  CAS  Google Scholar 

  310. Bukowski RM, Balcerzak SP, Bryan RM, Bonnet JD, Chen TT (1983) Randomized trial of 5-fluorouracil and mitomycin C with or without streptozotocin for advanced pancreatic cancer. A Southwest Oncology Group study. Cancer 52:1577–1582

    Article  PubMed  CAS  Google Scholar 

  311. Buroker T, Kim PN, Heilbrun L, Vaitkevicius VK (1978) 5-FU infusion with mitomycin C (MMC) vs 5-FU infusion with methyl-CCNU (Me) in the treatment of advanced upper gastrointestinal cancer. Proc Am Soc Clin Oncol 19:310

    Google Scholar 

  312. Carter SK, Comis RL (1975) Adenocarcinoma of the pancreas, prognostic variables, and criteria of response. In: Staquet MJ (ed) Cancer therapy: Prognostic factors and criteria of response. Raven, New York, pp 237–253

    Google Scholar 

  313. Frey C, Twomey P, Keehn R, Elliott D, Higgins G (1981) Randomized study of 5-fluorouracil and CCNU in pancreatic cancer: Report of the Veterans Administration Surgical Adjuvant Cancer Chemotherapy Study Group. Cancer 47:27–31

    Article  PubMed  CAS  Google Scholar 

  314. Gazet J-C, Smith R (1974) Intraarterial chemotherapy for patients with inoperable carcinoma of the pancreas. Proc R Soc Med 67:1182–1183

    PubMed  CAS  Google Scholar 

  315. Hafström L, Ihse I, Jönsson P-E, Lunderquist A, Strid-beck H (1980) Intraarterial 5-FU infusion with or without oral testolactone treatment in irresectable pancreatic cancer. Acta Chir Scand 146:445–448

    PubMed  Google Scholar 

  316. Hallengren B, Dymling J-F, Manhem P, Tennvall L, Tibblin S (1983) Unsuccessful DTIC treatment of patient with glucagonoma syndrome. Acta Med Scand 213:317–318

    Article  PubMed  CAS  Google Scholar 

  317. Herr RR, Jahnke HK, Argondelis AS (1967) Structure of streptozotocin. J Am Chem Soc 89:4808–4809

    Article  PubMed  CAS  Google Scholar 

  318. Horton J, Gelber RD, Engstrom P, Falkson G, Moertel CG, Brodovsky H, Douglass H (1981) Trials of single-agent and combination chemotherapy for advanced cancer of the pancreas. Cancer Treat Rep 65:65–68

    PubMed  CAS  Google Scholar 

  319. Junge U, Frerichs H, Creutzfeldt W (1979) Zytostatische Behandlung maligner endokriner Pankreastumo-ren und metastasierenden Karzinoiden mit Streptozotocin. Verh Dtsch Ges Inn Med 85:593–596

    Google Scholar 

  320. Kahn CR, Levy AG, Gardner JD, Miller JV, Gordon P, Schein PS (1975) Pancreatic cholera: Beneficial effects of treatment with streptozotocin. N Engl J Med 292:941–945

    Article  PubMed  CAS  Google Scholar 

  321. Kaplan RS (1978) Phase II trial of ICRF-159, ß-deoxy-thioguanosine, /?-2TGdR and galactilol in advanced measurable pancreatic carcinoma. A study of the GITSG. Proc Am Soc Clin Oncol 19:335

    Google Scholar 

  322. Kent RB, Van Heerden JA, Weiland LH (1981) Nonfunctioning islet cell tumors. Ann Surg 193:185–190

    Article  PubMed  Google Scholar 

  323. Kessinger A, Lemon HM, Foley JF (1977) The glucagonoma syndrome and its management. J Surg Oncol 9:419–424

    Article  PubMed  CAS  Google Scholar 

  324. Kessinger A, Foley J, Lemon HM (1983) Therapy of malignant apud cell tumors. Effectiveness of DTIC. Cancer 51:790–794

    CAS  Google Scholar 

  325. Klapdor R (1980) Ergebnisse und Überlegungen zur Chemotherapie des Pankreaskarzinoms. Med Welt 31:1853–1858

    PubMed  CAS  Google Scholar 

  326. Kurose T, Scino Y, Ishida H, Fujita J, Taminato T, Matsukura M, Imura H (1984) Successful treatment of metastastic glucagonoma with dacarbazine. Lancet 1:621–622

    Article  PubMed  CAS  Google Scholar 

  327. Macdonald JS, Widerlite L, Schein PS (1977) Biopsy, diagnosis, and chemotherapeutic management of pancreatic malignancy. Adv Pharmacol Chemother 14:107–141

    Article  PubMed  CAS  Google Scholar 

  328. Mallinson CN, Rake MO, Cocking JB et al. (1980) Chemotherapy in pancreatic cancer: Results of a controlled, prospective, randomized, multicenter trial. Br Med J 281:1589–1591

    Article  PubMed  CAS  Google Scholar 

  329. Marynick SP, Fagadan WR, Duncan LA (1980) Malignant glucagonoma syndrome: Response to chemotherapy. Ann Intern Med 93:453–454

    PubMed  CAS  Google Scholar 

  330. Moertel CG (1973) Exocrine pancreas. In: Holland JF, Frei E III (eds) Cancer medicine. Lea & Febiger, Philadelphia 1559

    Google Scholar 

  331. Moertel CG (1975) Clinical management of advanced gastrointestinal cancer. Cancer 36:675–682

    Article  PubMed  CAS  Google Scholar 

  332. Moertel CG, Lavin PT (1977) An evaluation of 5-FU, nitrosurea, and lactone combinations in the therapy of upper gastrointestinal cancer. Proc Am Soc Clin Oncol 18:344

    Google Scholar 

  333. Moertel CG, Reitemeier RJ, Schutt AJ (1971) Phase II study of streptozotocin (NSC-85998) in the treatment of advanced gastrointestinal cancer. Cancer Chemother Rep 55:303–307

    PubMed  CAS  Google Scholar 

  334. Moertel CC, Mittelman JA, Bakemeier RF, Engstrom P, Hanley J (1976) Sequential and combination chemotherapy of advanced gastric cancer. Cancer 38:678–682

    Article  PubMed  CAS  Google Scholar 

  335. Moertel CG, Douglass HO, Hanley JA, Carbone PP (1977) Treatment of advanced adenocarcinoma of the pancreas with combinations of streptozotocin plus 5-fluorouracil and streptozotocin plus cyclophosphamide. Cancer 40:605–608

    Article  PubMed  CAS  Google Scholar 

  336. Moertel CG, Hanley JA, Johnson LA (1980) Streptozotocin alone compared with streptozotocin plus 5-fluorouracil in the treatment of advanced islet cell carcinoma. N Engl J Med 303:1189–1194

    Article  PubMed  CAS  Google Scholar 

  337. Prinz RA, Badrinath K, Chejfec G, Freeark RJ, Greenlee HB (1983) „Nonfunctioning" islet cell carcinoma of the pancreas. Am Surg 49:345–349

    PubMed  CAS  Google Scholar 

  338. Rakieten N, Rakieten ML, Nadkarni MV (1969) Studies on the diabetogenic action of streptozotocin (NSC-37917). Cancer Chemother Rep 29:91–98

    Google Scholar 

  339. Van Rymenant M, Keymolen P, Procheret J, DeSchut-ter A, Kram R (1971) Action of testosterone and testolactone on isocitric dehydrogenase, aspartate transcar-bamylase and gluconate. Acta Endocrinol 66:498–501

    PubMed  Google Scholar 

  340. Schein PS (1976) Chemotherapy of gastrointestinal endocrine tumors. Excerpta Medica International Congress Series, No. 403. Proc. of the V. International Congress of Endocrinology. Endocrinology 2:453 57

    Google Scholar 

  341. Schein PS, De Lillis RA, Kahn CR, Gordon P, Kraft AR (1973) Islet cell tumors: Current concepts and management. Ann Intern Med 79:239–257

    PubMed  CAS  Google Scholar 

  342. Schein PS, Lavin PT, Moertel CG (1978) Randomized phase II clinical trial of adriamycin in advanced measurable pancreatic carcinoma: A Gastrointestinal Tumor Study Group report. Cancer 42:19–22

    Article  PubMed  CAS  Google Scholar 

  343. Smith FP, Schein PS (1979) Chemotherapy of pancreatic cancer. Semin Oncol 6:368–377

    PubMed  CAS  Google Scholar 

  344. Smith FP, Macdonald JS, Wooley PV et al. (1979) Phase II evaluation of FAM, 5-fluorouracil (F), adriamycin (A) and mitomycin-C (M) in advanced pancreatic cancer. Proc Am Soc Clin Oncol 20:415

    Google Scholar 

  345. Smith FP, Hoth DF, Levin B, Karlin DA, Macdonald JS, Wooley PV, Schein PS (1980) 5-Fluorouracil, adriamycin and mitomycin C (FAM) chemotherapy for advanced adenocarcinoma of the pancreas. Cancer 46:2014 2018

    Google Scholar 

  346. Sordillo PP, Magill GB (1982) Phase II trial of methyl-CCNU, vincristine, 5-fluorouracil, and streptozotocin (MOF-Strep) in patients with disseminated pancreatic carcinoma. Am J Clin Oncol 5:277–279

    Article  PubMed  CAS  Google Scholar 

  347. Stadil F, Stage G, Rehfeld JF, Efsen F, Fisherman K (1976) Treatment of Zollinger-Ellison syndrome with streptozotocin. N Engl J Med 294:1440–1442

    Article  PubMed  CAS  Google Scholar 

  348. Stolinsky DC, Sadoff L, Braunwald J, Bateman JR (1972) Streptozotocin in the treatment of cancer: Phase II study. Cancer 30:61–67

    Article  Google Scholar 

  349. Strauss GM, Weitzmann SA, Aoki TT (1979) Dimethyl-triazenoimidazole carboxamide therapy of malignant glucagonoma. Ann Intern Med 90:57–58

    PubMed  CAS  Google Scholar 

  350. Waddell WR (1973) Chemotherapy for carcinoma of the pancreas. Surgery 74:420–429

    PubMed  CAS  Google Scholar 

  351. Wiggans G, Schein PS, Macdonald JS, Schellinger D, Harbert J (1976) Computerized axial tomography for diagnosis of pancreatic cancer. Lancet 11:233–235

    Article  Google Scholar 

  352. Zelen M (1973) Keynote address of biostatistics and data retrieval. Cancer Chemother Rep 4:31–39

    CAS  Google Scholar 

Download references

Authors
  1. L. F. Hollender
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H.-J. Peiper
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Marchal
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. G. Fortner
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. Notter
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J.-H. Beyer
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Centre Hospitalier, Universitaire de Hautepierre, 1, Avenue Molière, F-67098, Strasbourg Cedex, France

    L. F. Hollender

  2. Klinik und Poliklinik für Allgemeinchirurgie, Georg-August-Universität, Robert-Koch-Str. 40, D-3400, Göttingen, Deutschland

    H.-J. Peiper

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hollender, L.F., Peiper, HJ., Marchal, J., Fortner, J.G., Notter, G., Beyer, JH. (1988). Pankreaskarzinom. In: Hollender, L.F., Peiper, HJ. (eds) Pankreaschirurgie. Die Praxis der Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95476-4_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-95476-4_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-95477-1

  • Online ISBN: 978-3-642-95476-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation