A Method for Local Evaluation of the Volume of Rapidly Exchangeable Water in the Human Brain

  • J. C. Depresseux


The quest for optimal accuracy, precision, sensitivity, and spatial and temporal resolution of the measurements, combined with considerations of feasibility and noninvasiveness has led physiologists and biomathematicians to design many different methodological approaches to the determination of regional cerebral blood flow (rCBF) in man by means of externally detected radioactive inert indicators. Those methods are all based upon variants of the model initially designed by Kety and Schmidt (1948) to describe the kinetics of nitrous oxide in the whole brain.


Positron Emission Tomography Cerebral Blood Flow Input Function Regional Cerebral Blood Flow Cereb Blood Flow 
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© Springer-Verlag Berlin Heidelberg 1983

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  • J. C. Depresseux

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